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... • states that genes for different traits segregate independently during the formation of gametes • Independent assortment accounts for the many genetic variations observed in plants animals, & other organisms. ...
national unit specification: general information
national unit specification: general information

... Describe DNA structure and its replication. Describe the stages of the cell cycle. Explain the stages involved in protein synthesis. Describe how genes are expressed. Describe the applications of DNA technology. ...
ª2010 Elsevier Ltd All rights reserved DOI 10.1016/j.cub.2010.06.022
ª2010 Elsevier Ltd All rights reserved DOI 10.1016/j.cub.2010.06.022

... that evolved from a single progenitor (P) in either a high-salt (S) or a low-glucose (M) environment [2]. These populations were propagated as batch-transferred cultures, with population size fluctuating daily between 106 (‘‘bottleneck size’’) and 108 individuals. We then demonstrated that fitness r ...
Neema Bhukhan
Neema Bhukhan

... identical patterns of non-coding sequence conservation in human, dog, and mouse DNA. Of the 14 conserved non-coding sequences found, 2 were determined to be gene regulatory elements. The results they obtained suggest that a large fraction of non-coding elements identified are conserved because of fu ...
Chapter 21 Nucleic Acids and Protein Synthesis
Chapter 21 Nucleic Acids and Protein Synthesis

...  While in the nucleus, the introns are removed from the pre-RNA.  The exons that remain are joined to form the mRNA that leaves the nucleus with the information for the synthesis of protein. ...
Ewens` sampling formula and related formulae: combinatorial proofs
Ewens` sampling formula and related formulae: combinatorial proofs

... where lineages have a common ancestor (Kingman, 1982). Mutations occur along the edges of the coalescent tree according to a Poisson process of intensity y=2. Many discrete population models are in the domain of attraction of the coalescent when time is measured appropriately. In a Wright–Fisher mod ...
Identification of the Missing Links in Prokaryotic Pentose Oxidation
Identification of the Missing Links in Prokaryotic Pentose Oxidation

... THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL. 281, NO. 37, pp. 27378 –27388, September 15, 2006 © 2006 by The American Society for Biochemistry and Molecular Biology, Inc. Printed in the U.S.A. ...
Complete Sequence of the Mitochondrial DNA of
Complete Sequence of the Mitochondrial DNA of

... is unusually variable. Complete mitochondrial gene organizations have been determined for five molluscan species (representing three different classes): the blue mussel Mytilus edulis, of the class Bivalvia (Hoffmann, Boore, and Brown 1992); the black chiton Katharina tunicata, of the class Polyplac ...
splicing
splicing

... by miRNAs - they found that the ARE of the human TNF mRNA activates translation during serum starvation, which arrests the cell cycle in the G1 phase • In particular, miR369-3, with the help of AGO2 and FXR1, activate translation of the TNF mRNA in serum-starved cells • miR369-3, with the help of ...
Identification and characterization of an early gene in the Lymantria
Identification and characterization of an early gene in the Lymantria

... immediately after the virus adsorption period and throughout the infection cycle. The early transcriptional start sites of G22 map to a sequence that resembles a subset of RNA polymerase II promoters/start sites that are found upstream of Drosophila melanogaster developmental and retrotransposon gen ...
BIO41 CH23.pptx
BIO41 CH23.pptx

... organism and its environment increases v  Because the environment can change, adaptive evolution is a continuous process v  Genetic drift and gene flow do not consistently lead to adaptive evolution as they can increase or decrease fitness, the match between an organism and its environment ...
Parasites, desiderata lists and the paradox of the organism
Parasites, desiderata lists and the paradox of the organism

... organisms, are not. Examine the logic of modern natural selection theory in sexual populations and observe that it is all about changes in frequencies of copies of things. In practice these things are genes, in the sense of Mendelian units independently assorting in gene pools, but any self-replicat ...
The meaning of systems biology
The meaning of systems biology

... part of the 20th century, most geneticists sought to understand heredity and chose to study traits in the organism that could be easily scored and could be used to reveal genetic mechanisms. This was later extended to powerful effect to use genetics to study cell biological and developmental mechani ...
The Homologous Drosophila Transcriptional Adaptors ADA2a and
The Homologous Drosophila Transcriptional Adaptors ADA2a and

... Ada2a Ada2b double mutants were constructed by recombining Ada2bd842 and Ada2ad189 into the same chromosome. The double mutants were selected on the basis of noncomplementation with either Df(3R)P14 or Df(3R)CA1. Eight independent P[Dtl⫹ Rpb4⫹] Ada2ad189 Ada2bd842/TM6C Tb Sb strains were used to tes ...
The Cell Nucleus…
The Cell Nucleus…

... – Cells contain a wide array of enzymes that can add or remove chemical groups to or from amino acid residues in the histone tails – The histone code hypothesis – 1. The state & activity of a particular region of chromatin depends upon the specific modifications, or combination of modifications, to ...
Alternative Splicing: How to Get More than One Protein from a Gene
Alternative Splicing: How to Get More than One Protein from a Gene

... Alternative Splicing: How to Get More than One Protein from a Gene Description: Use the word key from the “Protein Synthesis and Words” activity to demonstrate how eukaryotic cells may use one DNA sequence to code for multiple proteins. Eukaryotic cells might use the same gene or DNA sequence differ ...
Lecture 15
Lecture 15

... How Are Populations, Genes, and Evolution Related? • Evolutionary change occurs over time to populations • A population is a group that includes all members of a species living in a given area • Individuals live/die, reproduce/not …depending on their traits ...
Challenges of integrating conventional breeding and biotechnology
Challenges of integrating conventional breeding and biotechnology

... subjective exercise, based on the experience and subjective skill of a plant breeder to choose parents for designed crosses or populations, and to select out improved individuals or populations in the progenies of artificial or controlled natural crosses. Indeed, to date, in my experience, very few ...
outline29476
outline29476

... of complete haploid sets of chromosomes (e.g., triploidy, 3N = 69). His type of condition is incompatible with long-term survival. 2. Structural anomalies are rearrangements of genetic material within or between chromosomes. They usually result from breakage. B. Clinical example: Down syndrome, tris ...
Chromosomal
Chromosomal

... © 2011 Pearson Education, Inc. ...
Crossing over - JeongAPbiology
Crossing over - JeongAPbiology

... Types of Reproduction  Asexual ...
89 Electroporation-Mediated GFP Gene Transfer into Model
89 Electroporation-Mediated GFP Gene Transfer into Model

... as the selectable gene delivered by electroporation into the nuclear genome of unicellular C. reinhardtii. Hygromycin resistant transformants isolated by direct selection from the plates. Molecular and genetic analyses carried out on transformants revealed the nuclear genome is stably transformed, h ...
Extent of Gene Duplication in the Genomes of
Extent of Gene Duplication in the Genomes of

... the alignable region. This simple criterion does not specify the proportion of alignable regions. To reduce the chance of putting two nonhomologous proteins into the same family as a result of domain sharing, we required the alignable region between two proteins to be at least 80% of the longer prot ...
Non-coding RNAs are widely distributed in the 3 life domains
Non-coding RNAs are widely distributed in the 3 life domains

... CsrA and CsrA homolog RsmA and effect of sequestration by sRNA(A) Gene expression is controlled by CsrA binding to leader segments of target mRNAs (e.g. pgaABCD involved in PGA biosynthesis and export) affecting their translation and stability. CsrA activity is repressed via sequestration of CsrA b ...
The Molecular Basis of Inheritance
The Molecular Basis of Inheritance

...  In April 1953, Watson and Crick published a succinct, one-page paper in Nature reporting their double helix model of DNA. Concept 2: Many proteins work together in DNA replication and repair  The specific pairing of nitrogenous bases in DNA was the flash of inspiration that led Watson and Crick t ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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