The Biology and Evolution of Mammalian Y Chromosomes
... trigger testis formation during fetal development, setting in motion a cascade of events required for anatomic masculinization more broadly, including the production of testosterone (by testicular somatic cells known as Leydig cells). Although the Y chromosome triggers or activates the pathway of te ...
... trigger testis formation during fetal development, setting in motion a cascade of events required for anatomic masculinization more broadly, including the production of testosterone (by testicular somatic cells known as Leydig cells). Although the Y chromosome triggers or activates the pathway of te ...
Genome-wide histone modification patterns in
... bioRxiv preprint first posted online Feb. 15, 2016; doi: http://dx.doi.org/10.1101/039776. The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It is made available under a CC-BY 4.0 International license. ...
... bioRxiv preprint first posted online Feb. 15, 2016; doi: http://dx.doi.org/10.1101/039776. The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It is made available under a CC-BY 4.0 International license. ...
Ribosome profiling reveals post-transcriptional buffering of divergent
... role in divergent mRNA abundance than in divergent translation efficiency. Strikingly, most genes with aberrant transcript abundance in F1 hybrids (either over- or underexpressed compared to both parent species) did not exhibit aberrant ribosome occupancy. Our results show that interspecies differen ...
... role in divergent mRNA abundance than in divergent translation efficiency. Strikingly, most genes with aberrant transcript abundance in F1 hybrids (either over- or underexpressed compared to both parent species) did not exhibit aberrant ribosome occupancy. Our results show that interspecies differen ...
Chapter 11 Complex Inheritance and Human Heredity
... evaluated. The study of human genetics is difficult, because scien–tists are limited by time, ethics, and circumstances. For example, it takes decades for each generation to mature and then to have offspring when the study involves humans. Therefore, good record keeping, where it exists, helps scien ...
... evaluated. The study of human genetics is difficult, because scien–tists are limited by time, ethics, and circumstances. For example, it takes decades for each generation to mature and then to have offspring when the study involves humans. Therefore, good record keeping, where it exists, helps scien ...
Base excision repair
... Mutational changes in nucleotides that are outside of coding regions can also be silent. However, some noncoding sequences do have essential functions in gene regulation and, in this case, mutations in these sequences would have phenotypic effects. A nucleotide substitution that creates a new stop c ...
... Mutational changes in nucleotides that are outside of coding regions can also be silent. However, some noncoding sequences do have essential functions in gene regulation and, in this case, mutations in these sequences would have phenotypic effects. A nucleotide substitution that creates a new stop c ...
The Zebrafish Model Organism Database
... expression annotations such as ‘gene xyz is expressed in the kidney in abc mutant fish’ and phenotype annotations such as ‘the kidney is enlarged in abc mutant fish’. However, there was no way to record that the gene expression pattern of gene xyz in the kidney of abc mutant fish differed from the w ...
... expression annotations such as ‘gene xyz is expressed in the kidney in abc mutant fish’ and phenotype annotations such as ‘the kidney is enlarged in abc mutant fish’. However, there was no way to record that the gene expression pattern of gene xyz in the kidney of abc mutant fish differed from the w ...
Protein Synthesis
... DNA molecules, transfers that information to smaller RNA molecules, then assembles the proteins from amino acids. All that makes sense if you know what DNA and RNA are. I want to do the review. ...
... DNA molecules, transfers that information to smaller RNA molecules, then assembles the proteins from amino acids. All that makes sense if you know what DNA and RNA are. I want to do the review. ...
The Mechanism of Translation II
... Administration. The solution was created by the grantee and does not necessarily reflect the official position of the U.S. Department of Labor. The Department of Labor makes no guarantees, warranties, or assurances of any kind, express or implied, with respect to such information, including any info ...
... Administration. The solution was created by the grantee and does not necessarily reflect the official position of the U.S. Department of Labor. The Department of Labor makes no guarantees, warranties, or assurances of any kind, express or implied, with respect to such information, including any info ...
Acanthamoeba mitochondrial 16S rDNA sequences: inferred
... with the large majority of AK cases. This genotype encompasses at least five species that have been differentiated largely on the basis of morphology. However, because it is generally agreed that morphology alone is unreliable for classification of this organism, there is a need for other markers th ...
... with the large majority of AK cases. This genotype encompasses at least five species that have been differentiated largely on the basis of morphology. However, because it is generally agreed that morphology alone is unreliable for classification of this organism, there is a need for other markers th ...
Document
... Concept 14.3: Inheritance patterns are often more complex than predicted by simple Mendelian genetics • The relationship between genotype and phenotype is rarely as simple as in the pea plant characters Mendel studied • Many heritable characters are not determined by only one gene with two alleles ...
... Concept 14.3: Inheritance patterns are often more complex than predicted by simple Mendelian genetics • The relationship between genotype and phenotype is rarely as simple as in the pea plant characters Mendel studied • Many heritable characters are not determined by only one gene with two alleles ...
Linear and non-linear dependencies between copy number
... NDRG1 was negative, suggesting a mechanism for suppressing expression despite amplification; on the other hand, the positive coefficient for ERBB2 suggested the existence of further enhancement of expression. Consequently, the different shapes of non-linearity may suggest different molecular mechani ...
... NDRG1 was negative, suggesting a mechanism for suppressing expression despite amplification; on the other hand, the positive coefficient for ERBB2 suggested the existence of further enhancement of expression. Consequently, the different shapes of non-linearity may suggest different molecular mechani ...
Types of variation in DNA-A among isolates of East African cassava
... Inspection of the nucleotide sequences of the AC2 and AC3 genes showed that substitutions are scattered along them, and that several do not change the amino acid encoded. This pattern of variation is therefore typical of that produced as the result of the accumulation of point mutations in different ...
... Inspection of the nucleotide sequences of the AC2 and AC3 genes showed that substitutions are scattered along them, and that several do not change the amino acid encoded. This pattern of variation is therefore typical of that produced as the result of the accumulation of point mutations in different ...
Cloning and expression of proteins from Mycobacterium smegmatis
... . According to the United States National Institute of Allergy and Infectious Diseases (NIAID) some two billion people are believed to be infected with M. tuberculosis [14]. An infected host with a fully functional immune system can carry latent TB for a very long time. Not only the developing count ...
... . According to the United States National Institute of Allergy and Infectious Diseases (NIAID) some two billion people are believed to be infected with M. tuberculosis [14]. An infected host with a fully functional immune system can carry latent TB for a very long time. Not only the developing count ...
References - Plant Developmental Biology
... progenitors in the embryo and apical meristems. Our primary goal is to gain experience in the interpretation of the mature structure of wild-type Arabidopsis plants (and the developmental basis for that structure) as a baseline for future comparison with mutant phenotypes. In this lab we will use se ...
... progenitors in the embryo and apical meristems. Our primary goal is to gain experience in the interpretation of the mature structure of wild-type Arabidopsis plants (and the developmental basis for that structure) as a baseline for future comparison with mutant phenotypes. In this lab we will use se ...
The Answer Is Fifteen Percent - CHEST Journal
... respiratory illness. These studies have not been conclusive. Because inflammatory processes are likely to be important in the pathogenesis of COPD, genetic polymorphisms that effect inflammatory mediators or the immune response may be of interest. Candidate genes that are involved with inflammatory ...
... respiratory illness. These studies have not been conclusive. Because inflammatory processes are likely to be important in the pathogenesis of COPD, genetic polymorphisms that effect inflammatory mediators or the immune response may be of interest. Candidate genes that are involved with inflammatory ...
Molecular Cloning of Clostridium Perfringens Type B Vaccine Strain
... Figure 4. pJETβ plasmid extraction result. Lane 1: uncut recombinant pJETβ with 3 kb size; lane 2: 100 bp plus DNA ladder; lane 3: digested pJETβ with 1 kb insert size. ...
... Figure 4. pJETβ plasmid extraction result. Lane 1: uncut recombinant pJETβ with 3 kb size; lane 2: 100 bp plus DNA ladder; lane 3: digested pJETβ with 1 kb insert size. ...
PDF
... Usually, mature 39 ends of almost all eukaryotic mRNAs are created by a two-step reaction that involves an endonucleolytic cleavage of the pre-mRNA, followed by synthesis of a polyadenylate tail onto the upstream cleavage product. Polyadenylation influences many aspects of mRNA metabolism: transcrip ...
... Usually, mature 39 ends of almost all eukaryotic mRNAs are created by a two-step reaction that involves an endonucleolytic cleavage of the pre-mRNA, followed by synthesis of a polyadenylate tail onto the upstream cleavage product. Polyadenylation influences many aspects of mRNA metabolism: transcrip ...
PDF - WashU Epigenome Browser
... Learn more about the supported numerical track formats bedGraph (http: //wiki.wubrowse.org/bedgraph) and bigWig (http://wiki.wubrowse.org/bigwig). ...
... Learn more about the supported numerical track formats bedGraph (http: //wiki.wubrowse.org/bedgraph) and bigWig (http://wiki.wubrowse.org/bigwig). ...
Guidelines for Gene Expression Patterns papers
... (1) Is this manuscript appropriate for MOD or for Gene Expression Patterns (GEP)? Does the ms. contain cloning and/or gene expression data? ...
... (1) Is this manuscript appropriate for MOD or for Gene Expression Patterns (GEP)? Does the ms. contain cloning and/or gene expression data? ...
Molecular Biology Reports
... antioxidant enzymes and low-molecular weight antioxidants. Particularly, to protect themselves against the toxic ROS that result from stress conditions including dehydration, plants possess very efficient defense mechanisms that include the expression and activation of genes related to intracellular ...
... antioxidant enzymes and low-molecular weight antioxidants. Particularly, to protect themselves against the toxic ROS that result from stress conditions including dehydration, plants possess very efficient defense mechanisms that include the expression and activation of genes related to intracellular ...
The microRNA, miR-29c, participates in muscle development
... that microRNAs can participate in cell proliferation, differentiation and apoptosis[4–6]. The miR-29 family contains three members, miR-29a, miR-29b and miR29c[7], and they have similar expression patterns and biofunctions. MiR-29 can participate in many physiological and chemical processes. It has ...
... that microRNAs can participate in cell proliferation, differentiation and apoptosis[4–6]. The miR-29 family contains three members, miR-29a, miR-29b and miR29c[7], and they have similar expression patterns and biofunctions. MiR-29 can participate in many physiological and chemical processes. It has ...
Etude Annotation
... Bxz3 for now, because these two phages have annotations in GenBank already—which means that when I look for individual genes using BLAST on the NCBI website, I should see these genes, and they will ...
... Bxz3 for now, because these two phages have annotations in GenBank already—which means that when I look for individual genes using BLAST on the NCBI website, I should see these genes, and they will ...
chapter 15 the nervous system
... 21. You studying for an upcoming biology exam. 22. You are rushing to class because you are late and almost fall on an icy patch of pavement, but manage to keep your balance. 23. You feel angry and embarrassed when you rip your pants. 24. A stroke leaves a person unable to speak, what part of the br ...
... 21. You studying for an upcoming biology exam. 22. You are rushing to class because you are late and almost fall on an icy patch of pavement, but manage to keep your balance. 23. You feel angry and embarrassed when you rip your pants. 24. A stroke leaves a person unable to speak, what part of the br ...
Indigenous Peoples - Council for Responsible Genetics
... do or make decisions for you, be they pro or con. Our intent is to present the subject and the issues so that you can make intelligent, well thought-out and informed decisions about genetic research in indigenous communities. We present a broad perspective on the concerns and potential negative aspe ...
... do or make decisions for you, be they pro or con. Our intent is to present the subject and the issues so that you can make intelligent, well thought-out and informed decisions about genetic research in indigenous communities. We present a broad perspective on the concerns and potential negative aspe ...
Gene
A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.