Characterization of the first cultured representative of
... using the ‘RS_HGAP_Assembly.1’ protocol included in SMRTPortal version 2.1.1 including all five SMRT cells applying parameters described previously (Ben Hania et al., 2015), but not allowing partial alignments. Finally, one chromosomal contig could be obtained, which was trimmed, circularized and ad ...
... using the ‘RS_HGAP_Assembly.1’ protocol included in SMRTPortal version 2.1.1 including all five SMRT cells applying parameters described previously (Ben Hania et al., 2015), but not allowing partial alignments. Finally, one chromosomal contig could be obtained, which was trimmed, circularized and ad ...
Accounting for Non-Genetic Factors Improves the Power of eQTL
... large sets of genes, jointly promoting or inhibiting their expression. An alternative approach used by (2) is to ignore those genes whose measured expression level may be due to environmental factors (a heuristic score is used to represent the heritability component of a gene probe). However, this a ...
... large sets of genes, jointly promoting or inhibiting their expression. An alternative approach used by (2) is to ignore those genes whose measured expression level may be due to environmental factors (a heuristic score is used to represent the heritability component of a gene probe). However, this a ...
Genetic data indicate that proteins containing the GGDEF domain
... pYhcK £occulated heavily (Fig. 3B,C). Strong £uorescence was observed in and around these aggregates in the microscope after staining with Calco£uor (data not shown). Plasmid pYhcK caused the strongest aggregation in the liquid culture (Fig. 3C). These results support the data presented by Amikam an ...
... pYhcK £occulated heavily (Fig. 3B,C). Strong £uorescence was observed in and around these aggregates in the microscope after staining with Calco£uor (data not shown). Plasmid pYhcK caused the strongest aggregation in the liquid culture (Fig. 3C). These results support the data presented by Amikam an ...
Mutation Types - CK
... There are a variety of types of mutations. Two major categories of mutations are germline mutations and somatic mutations. • Germline mutations occur in gametes. These mutations are especially significant because they can be transmitted to offspring and every cell in the offspring will have the muta ...
... There are a variety of types of mutations. Two major categories of mutations are germline mutations and somatic mutations. • Germline mutations occur in gametes. These mutations are especially significant because they can be transmitted to offspring and every cell in the offspring will have the muta ...
Independent assortment - Merrillville Community School
... red eyes, normal bristles X brown eyes, stubble bristles all red eye, normal bristle red eyes, normal bristles X red eyes, normal bristles 28 red eyes, normal bristles 0 red eyes, stubble bristles 0 brown eye, normal bristles 9 brown eye, stubble bristle ...
... red eyes, normal bristles X brown eyes, stubble bristles all red eye, normal bristle red eyes, normal bristles X red eyes, normal bristles 28 red eyes, normal bristles 0 red eyes, stubble bristles 0 brown eye, normal bristles 9 brown eye, stubble bristle ...
Legal Liability for Genetic Injuries From Radiation
... from man-made sources, may cause genetic damage. This scientific knowledge has already acquired legal significance by serving as a basis for governmental recommendations and regulations controlling radiation exposure of workers and the general public. 1 In addition, a personal injury case in which a ...
... from man-made sources, may cause genetic damage. This scientific knowledge has already acquired legal significance by serving as a basis for governmental recommendations and regulations controlling radiation exposure of workers and the general public. 1 In addition, a personal injury case in which a ...
Bayesian Partition Models for Identifying Expression Quantitative
... epistasis association mapping (BEAM) model to detect epistatic interactions in genome-wide casecontrol studies, where response Y is a binary variable indicating disease status. The BEAM model can be viewed as a generalization of the naïve Bayes (NB) model, which models Pr(X|Y) instead of Pr(Y|X). Mo ...
... epistasis association mapping (BEAM) model to detect epistatic interactions in genome-wide casecontrol studies, where response Y is a binary variable indicating disease status. The BEAM model can be viewed as a generalization of the naïve Bayes (NB) model, which models Pr(X|Y) instead of Pr(Y|X). Mo ...
Investigation of Four Genes Responsible for Autosomal Recessive
... a consanguineous Pakistani family. GALK1 found to be highly expressed in many human organs from foetuses to adults; brain, heart, kidney, liver, lung, muscle and spleen ...
... a consanguineous Pakistani family. GALK1 found to be highly expressed in many human organs from foetuses to adults; brain, heart, kidney, liver, lung, muscle and spleen ...
Pol Is a Candidate for the Mouse Pulmonary
... in adenoma susceptibility between A/J mice and BALB/cJ mice (7). Par2 is mapped to the mouse chromosome 18 and accounts for 60% phenotype variance (7–9). The resistance of BALB/cJ mice appears due to the interaction between the Pas1 QTL and Par2 QTL in the BALB/cJ mouse genome (10). We previously us ...
... in adenoma susceptibility between A/J mice and BALB/cJ mice (7). Par2 is mapped to the mouse chromosome 18 and accounts for 60% phenotype variance (7–9). The resistance of BALB/cJ mice appears due to the interaction between the Pas1 QTL and Par2 QTL in the BALB/cJ mouse genome (10). We previously us ...
MONOHYBRID PROBLEMS
... Before genetic problems may be adequately understood and solved, you must first understand the process of meiosis and also know how to apply the following. Homologous Chromosomes: chromosomes that are similar in size, shape and carry similar genetic information. One comes from the mother and one fro ...
... Before genetic problems may be adequately understood and solved, you must first understand the process of meiosis and also know how to apply the following. Homologous Chromosomes: chromosomes that are similar in size, shape and carry similar genetic information. One comes from the mother and one fro ...
gene_expression
... It is very difficult to partition data into an “unknown” number of clusters Most algorithms assume that K (number of clusters) is known Try different values of K, find the one that results in best clustering Very expensive ...
... It is very difficult to partition data into an “unknown” number of clusters Most algorithms assume that K (number of clusters) is known Try different values of K, find the one that results in best clustering Very expensive ...
Chapter 8: Variation in Chromosome Structure and Number
... single chromosome (or sometimes two), and how this may influence the expression of genes and the phenotype of the organism. Typically, student difficulties with this chapter rest primarily in the terminology associated with each form of variation. One of the best mechanisms of studying this material ...
... single chromosome (or sometimes two), and how this may influence the expression of genes and the phenotype of the organism. Typically, student difficulties with this chapter rest primarily in the terminology associated with each form of variation. One of the best mechanisms of studying this material ...
Genetics Part I
... We will begin by looking at a special kind of cell division called meiosis. Meiosis is from the Greek word for "diminution," which means to make smaller. This is the process that results in egg and sperm cells with one half of the normal number of chromosomes. Egg and sperm unite to form a new indiv ...
... We will begin by looking at a special kind of cell division called meiosis. Meiosis is from the Greek word for "diminution," which means to make smaller. This is the process that results in egg and sperm cells with one half of the normal number of chromosomes. Egg and sperm unite to form a new indiv ...
Nucleotide Sequence Preservation of Human
... humans (5, 21). Three additional between-individual differences outside the Dloop region of mtDNA were identified in this study. Substitution of cytidine for thymidine at L-strand positions 9698 and 9725 was found in all clones containing these regions from Patient CML/BC. Both of these base substit ...
... humans (5, 21). Three additional between-individual differences outside the Dloop region of mtDNA were identified in this study. Substitution of cytidine for thymidine at L-strand positions 9698 and 9725 was found in all clones containing these regions from Patient CML/BC. Both of these base substit ...
Harnessing gene expression to identify the genetic basis of drug
... Box 1 (A) Growth in the presence of a subset of drugs is represented by the heat map on the left (blue corresponds to low growth yield and yellow to high growth yield). Each row represents the data for a single drug (SMP10 is 1,9-pyrazoloanthone, DFI is diphenyliodonium and SK&F is SK&F 96365) and e ...
... Box 1 (A) Growth in the presence of a subset of drugs is represented by the heat map on the left (blue corresponds to low growth yield and yellow to high growth yield). Each row represents the data for a single drug (SMP10 is 1,9-pyrazoloanthone, DFI is diphenyliodonium and SK&F is SK&F 96365) and e ...
Scoring Guidelines - Ohio Assessment Systems
... Life is specified by genomes. Each organism has a genome that contains all of the biological information needed to build and maintain a living example of that organism. The biological information contained in a genome is encoded in its deoxyribonucleic acid (DNA) and is divided into discrete units c ...
... Life is specified by genomes. Each organism has a genome that contains all of the biological information needed to build and maintain a living example of that organism. The biological information contained in a genome is encoded in its deoxyribonucleic acid (DNA) and is divided into discrete units c ...
- Wiley Online Library
... Griffith in 1928 (Griffith, 1928) when he studied the conditions responsible for acquisition of a capsule by unencapsulated strains of Streptococcus pneumoniae. The molecular basis of this phenomenon was not understood, however, before DNA was identified as the transforming agent by Avery and co-wor ...
... Griffith in 1928 (Griffith, 1928) when he studied the conditions responsible for acquisition of a capsule by unencapsulated strains of Streptococcus pneumoniae. The molecular basis of this phenomenon was not understood, however, before DNA was identified as the transforming agent by Avery and co-wor ...
A Study of Gene Linkage and Mapping Using Tetrad Analysis
... studies of meiosis show that this exchange, called crossing over, takes place during prophase I when double-chromatid, homologous chromosomes are in synapsis. During crossing over, breakagerefusion points called chiasmata develop between synapsed chromosomes. These chiasmata result from pieces of th ...
... studies of meiosis show that this exchange, called crossing over, takes place during prophase I when double-chromatid, homologous chromosomes are in synapsis. During crossing over, breakagerefusion points called chiasmata develop between synapsed chromosomes. These chiasmata result from pieces of th ...
Acta Biotheoretica 47: 29-40, 1999 ON THE ADAPTIVE VALUE OF
... genetic resistance to antibiotics and pesticides (Jaffe et al. 1997). In this agent based adaptive model, each individual was simulated as an autonomous agent which related to the environment and to other individuals according to the alleles it carried in its set of genes or loci as given in Table I ...
... genetic resistance to antibiotics and pesticides (Jaffe et al. 1997). In this agent based adaptive model, each individual was simulated as an autonomous agent which related to the environment and to other individuals according to the alleles it carried in its set of genes or loci as given in Table I ...
Commentary: Genotype does not determine phenotype
... Wilhelm Johannsen’s genotype theory. Journal of the History of ...
... Wilhelm Johannsen’s genotype theory. Journal of the History of ...
array CGH - Unique The Rare Chromosome Disorder Support Group
... With an array CGH test is often possible to determine how many and which genes are missing or duplicated. At present we only understand the role of a small minority of genes and their association with particular clinical features. However, where a gene’s association with a particular clinical featur ...
... With an array CGH test is often possible to determine how many and which genes are missing or duplicated. At present we only understand the role of a small minority of genes and their association with particular clinical features. However, where a gene’s association with a particular clinical featur ...
Enlis Genome Research - Release Notes
... - Gene Categories tool: Added a tissue expression section to view genes expressed in 44 different tissues. Each tissue type has a separate category for three types of expression data: High Expression, Medium/High Expression, and Non-ubiquitously Expressed. In the High and Medium/High Expression cate ...
... - Gene Categories tool: Added a tissue expression section to view genes expressed in 44 different tissues. Each tissue type has a separate category for three types of expression data: High Expression, Medium/High Expression, and Non-ubiquitously Expressed. In the High and Medium/High Expression cate ...
Gene
A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.