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Extracellular matrix gene expression in the developing
Extracellular matrix gene expression in the developing

... Embryonic development requires the establishment of a functional circulatory system early in embryogenesis. The general outline of the forming vascular network is established in the absence of blood flow by endothelial cells through angiogenic or vasculogenic processes. With the initiation of blood ...
The amphioxus hairy family: differential fate after duplication.
The amphioxus hairy family: differential fate after duplication.

... Several representatives of the hairy family have been so far isolated from a range of protostome and vertebrate species. In protostomes such as Drosophila they have been implicated in segmentation, peripheral nervous system development, and in somatic sex determination. In Tribolium, only a role dur ...
Type of Leopard Gecko Picture Gene
Type of Leopard Gecko Picture Gene

... Looks like Normal, but bigger. Giant Male: 90-109g in first year of life Female: 80-89g in first year of life Supergiant Looks like Normal, but bigger. Male: More than 110g at 1 year old Female: More than 90g at 1 year old Weights for all geckos other than Giant and Supergiant: Male: 70-90g (as adul ...
Complex Inheritance of the 5-Lipoxygenase Locus
Complex Inheritance of the 5-Lipoxygenase Locus

... (Apoe/) backgrounds. However, they observed that 5LO/apoE/ mice developed fewer aneurysms than Apoe/ mice. In light of the supporting evidence favoring the role of the 5LO pathway in atherosclerosis from both mouse and human studies, we reasoned that the differing conclusions drawn from this ...
An Evolutionary Approach Towards Time Preferences∗
An Evolutionary Approach Towards Time Preferences∗

... We interpret a gene as a choice behavior. Hence, the choices an individual makes along her life time is determined solely by her gene. Since children inherit their genes from their parents, they make the same choices as their parents would have if they were in the same situation. A population is def ...
Population genetics and the modern synthesis of evolutionary theory
Population genetics and the modern synthesis of evolutionary theory

... − An individual's phenotype is the result of the interaction of both genes and environment − You can't have a phenotype without genes, and you can't have a phenotype that did not develop in some environment − both are necessarily part of the process − so the genetic processes we are looking at are n ...
A selfish origin for recombination
A selfish origin for recombination

... 1996; Paques and Haber, 1999). Throughout this discussion I will refer to the physical process of interaction and exchange between two DNA molecules as crossing over, and recombination will mean a possible outcome of crossing over (producing recombinant chromosomes), the other possible outcome being ...
Supplementary Notes S1 (doc 64K)
Supplementary Notes S1 (doc 64K)

... At least 1 probe was selected for 10,675 (97%) of the total 11,000 regions. 96% of regions have 6 or more probes. Most regions are ~1200 bp in size and typically have 25-35 probes. Larger regions may have as many as 62 probes. ...
Practice with Punnett Squares
Practice with Punnett Squares

... 10. What would the offspring phenotype and genotype probabilities be when a pea plant with constricted seed pods crossed with a plant that is heterozygous for inflated seed pods? You will need the pea plant chart on the next page to complete this problem. ...
Molecular Mechanisms of Developmental Review
Molecular Mechanisms of Developmental Review

... modulated by hormonal signaling (Antebi et al., 2000). Functions for daf-12 are discussed in more detail below. In conclusion, the heterochronic gene cascades that control developmental timing in C. elegans may involve at least three cases of negative posttranscriptional regulation. Two of these are ...
Transcription regulation of the Escherichia coli pcnB gene coding for
Transcription regulation of the Escherichia coli pcnB gene coding for

... does not introduce any long-lasting conformational alterations to this enzyme (Szalewska-Palasz 2008). The second eVector of the stringent response is the DksA protein, which was found as an indispensable factor for ppGpp-mediated eVects on ribosomal promoters in vivo (Paul et al. 2004). This protei ...
Linkage, Recombination, and the Mapping of Genes on Chromosomes
Linkage, Recombination, and the Mapping of Genes on Chromosomes

... This separation of genes on the same chromosome is the result of recombination, the occurrence in progeny of new gene combinations not seen in previous generations. (Note that recombinant progeny can result in either of two ways: from the recombination of genes on the same chromosome during gamete f ...
Presentation
Presentation

... This is when one allele of a pair isn’t fully dominant over its partner, so a heterozygous phenotype somewhere in between the two homozygous phenotypes emerges (creating a ...
[Full text/PDF]
[Full text/PDF]

... In previous studies, many genes have been detected but it is hard to replicate due to different heterogeneities of population and different phenotypes for COPD[8–9]. The ratio of FEV1 (forced expiratory volume in one second) to FVC (forced vital capacity) is the most important index for doctors to d ...
Solid Tumour Section Nervous system: Astrocytic tumors Atlas of Genetics and Cytogenetics
Solid Tumour Section Nervous system: Astrocytic tumors Atlas of Genetics and Cytogenetics

... frequently altered in these tumors: in 33-68% of primary glioblastomas and 25% of anaplastic astrocytomas. The Rb gene located on13q chromosome plays an important role in the malignant progression of gliomas. The p53 gene is a tumor suppressor gene located on chromosome 17p13.1; loss or mutation of ...
Recent and ongoing selection in the human genome
Recent and ongoing selection in the human genome

... have recently taken advantage of this fact to quantify positive selection acting in the genome on the human lineage leading from the ancestor of human and chimpanzees to modern humans18–20. In general, these studies have identified genes involved in immune-related functions, spermatogenesis, olfacti ...
Coevolution of an aminoacyl-tRNA synthetase with its tRNA substrates
Coevolution of an aminoacyl-tRNA synthetase with its tRNA substrates

... (from E. coli to D. radiodurans and Corynebacterium) of the genes encoding these precisely truncated GluRS fragments suggests that these proteins may have a yet unknown function. Nonetheless, GluX was not analyzed further. Class I lysyl-tRNA synthetase (LysRS) is structurally very related (27) and d ...
Pierre MADL Div. of Material Sciences Dep
Pierre MADL Div. of Material Sciences Dep

... The idea that germline cells contain information that passes to each generation unaffected by experience and independent of the somatic (body) cells, came to be referred to as the Weismann barrier, and is frequently quoted as putting a temporary end to the theory of Lamarck and the inheritance of ac ...
Molecular and Cellular Biology, September 2000, p
Molecular and Cellular Biology, September 2000, p

... dependent activity of the histone H4 gene promoter (24, 43). All highly conserved nucleotide motifs in the consensus H4 site II sequence are absolutely conserved in the proximal promoter region of all known vertebrate H10 genes (Fig. 1B). These observations strongly suggest that at least in prolife ...
Lecture 7: Gene Finding by Computational Analysis Gene
Lecture 7: Gene Finding by Computational Analysis Gene

... human genome • For gene that encodes protein – In Prokaryotic genome, one gene corresponds to one protein – In Eukaryotic genome, one gene can corresponds to more than one protein because of the process “alternative splicing” ...
A deflationary account of information in biology - Philsci
A deflationary account of information in biology - Philsci

... genetics are mostly equiprobable, H is uninformative to biologists. Again, although Maynard Smith doesn’t mention it, there is a problem of analogues. What is the channel, for example (Oyama 2000: 76)? mRNA is generated as needed, and there appears to be no bandwidth limitations, although clearly th ...
Towards an accurate identification of mosaic genes and partial
Towards an accurate identification of mosaic genes and partial

... transferred fragments can be detected using the new method by treating the complete genomes of involved organisms on the gene-by-gene basis. The most significant among the obtained partial transfers can then be merged to form longer sequence segments affected by HGT. Furthermore, any existing method ...
Probabilistic Reconciliation Analysis for Genes and Pseudogenes
Probabilistic Reconciliation Analysis for Genes and Pseudogenes

... Mendel well known, and suggested that Mendelian traits are the heritable elements transferring along the germ line. He also reconciled the Darwin’s pangenesis theory with Weismann’s germ-soma cells distinction, by saying that pangenes according to Darwin theory are located in the nucleus of cell, wh ...
cached copy
cached copy

... complementary bases in the corresponding order— the base adenine on one strand pairs with thymine on the opposite strand, and cytosine binds with guanine. At first sight, it does not appear that DNA can lead to interesting structures. Naturally occurring DNA forms a linear chain, like a long piece of ...
NCEA Level 1 Science (90948) 2013
NCEA Level 1 Science (90948) 2013

... to reproduce, if conditions are stable could introduce variation, which may be counterproductive. • Gametes are sex cells (sperm and egg) which are formed in the testes and ovaries. During gamete formation (meiosis), the homologous chromosomes are halved and the gamete will inherit one of each pair ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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