New Developments in Tay-Sachs Disease
... Several therapeutic interventions have been attempted, and some have recently undergone clinical trials. In the past, therapeutic enzyme replacement7 and bone marrow transplantation performed on individual patients has shown no benefit in Tay-Sachs infants. While intravenous administration of enzyme ...
... Several therapeutic interventions have been attempted, and some have recently undergone clinical trials. In the past, therapeutic enzyme replacement7 and bone marrow transplantation performed on individual patients has shown no benefit in Tay-Sachs infants. While intravenous administration of enzyme ...
Seizure Disorders
... Hyperexcitation of glutamate neurons. Many causes: Seizures are symptoms, not a disease. Presence of sensory or cognitive dysfunction is dependent on affected area(s) Prevalence: 0.6% of the population Incidence: 15,500 new cases per year (Epilepsy Canada) PSYC4080 ...
... Hyperexcitation of glutamate neurons. Many causes: Seizures are symptoms, not a disease. Presence of sensory or cognitive dysfunction is dependent on affected area(s) Prevalence: 0.6% of the population Incidence: 15,500 new cases per year (Epilepsy Canada) PSYC4080 ...
pupillae and ciliary muscle following third-nerve
... Bender and Fulton (1939) showed that in monkeys, following regeneration of the sectioned third cranial nerve, a mass innervation of the muscles supplied by the third nerve develops. This resulted in limitation of upward and downward movement of the eye owing to synkinesis of the antagontist muscle. ...
... Bender and Fulton (1939) showed that in monkeys, following regeneration of the sectioned third cranial nerve, a mass innervation of the muscles supplied by the third nerve develops. This resulted in limitation of upward and downward movement of the eye owing to synkinesis of the antagontist muscle. ...
up-regulation - Bakersfield College
... Drugs suggest a role for serotonin and GABA Amygdala, due to its role in fear and defensive behavior, thought to be involved No pathology yet identified Difficult to study neural basis of anxiety Diversity and subtlety of symptoms Abnormal breathing in anxious patients complicates functional b ...
... Drugs suggest a role for serotonin and GABA Amygdala, due to its role in fear and defensive behavior, thought to be involved No pathology yet identified Difficult to study neural basis of anxiety Diversity and subtlety of symptoms Abnormal breathing in anxious patients complicates functional b ...
Hikosaka O - Laboratory of Sensorimotor Research Bibliographies
... Abstract: Using GABAergic outputs from the SNr or GPi, the basal ganglia exert inhibitory control over several motor areas in the brainstem which in turn control the central pattern generators for the basic motor repertoire including eye–head orientation, locomotion, mouth movements, and vocalizatio ...
... Abstract: Using GABAergic outputs from the SNr or GPi, the basal ganglia exert inhibitory control over several motor areas in the brainstem which in turn control the central pattern generators for the basic motor repertoire including eye–head orientation, locomotion, mouth movements, and vocalizatio ...
efficacy of levetiracetam in a case of stiff-person syndrome
... In spite of being almost impossible to forget its classical clinical features, SPS is a rare entity and it can be underdiagnosed by other medical areas. An important diagnostic criterion is the presence of continuous motor unit activity on electromyography despite attempted relaxation.(2) Continuous ...
... In spite of being almost impossible to forget its classical clinical features, SPS is a rare entity and it can be underdiagnosed by other medical areas. An important diagnostic criterion is the presence of continuous motor unit activity on electromyography despite attempted relaxation.(2) Continuous ...
Deep Brain Stimulation
... Primary Dystonia DBS for the treatment of primary dystonia received FDA approval through the Humanitarian Device Exemption (HDE) process.[20] The HDE approval process is available for those conditions that affect less than 4,000 Americans per year. According to this approval process, the manufacture ...
... Primary Dystonia DBS for the treatment of primary dystonia received FDA approval through the Humanitarian Device Exemption (HDE) process.[20] The HDE approval process is available for those conditions that affect less than 4,000 Americans per year. According to this approval process, the manufacture ...
EMG Blind Spots Disorders of the NMJ
... 45 year old man with progressive ptosis, dysphagia FH: mother with “seronegative myasthenia gravis” Examination: bilateral ptosis and extraocular muscle weakness without clear fatigability; mild proximal limb weakness Antibody testing: AChR and MuSK Antibodies (-) EMG and NCS: decrement on repetitiv ...
... 45 year old man with progressive ptosis, dysphagia FH: mother with “seronegative myasthenia gravis” Examination: bilateral ptosis and extraocular muscle weakness without clear fatigability; mild proximal limb weakness Antibody testing: AChR and MuSK Antibodies (-) EMG and NCS: decrement on repetitiv ...
Parkinsonism and multiple sclerosis-Is there association? Clinical
... striatum, with normal findings on the left side (Fig. 3). These findings were consistent with unilateral Parkinson's disease (PD). The diagnosis was relapsing remitting multiple sclerosis and PD. Case 2. In August 2000, a 53-year-old woman developed resting tremor and clumsiness in the right arm and ...
... striatum, with normal findings on the left side (Fig. 3). These findings were consistent with unilateral Parkinson's disease (PD). The diagnosis was relapsing remitting multiple sclerosis and PD. Case 2. In August 2000, a 53-year-old woman developed resting tremor and clumsiness in the right arm and ...
CT and MR of MELAS Syndrome
... both cortex as well as white matter, with relative sparing of the frontal lobes and brainstem. The only drawback of MR is its inability to demonstrate basal ganglia calcification , which may be a prominent feature. Although the biochemical disorder in mitochondrial myopathies is not known exactly, v ...
... both cortex as well as white matter, with relative sparing of the frontal lobes and brainstem. The only drawback of MR is its inability to demonstrate basal ganglia calcification , which may be a prominent feature. Although the biochemical disorder in mitochondrial myopathies is not known exactly, v ...
INCREASED INTRACRANIAL PRESSURE, CERE BRAL EDEMA
... Increased intracranial pressure results from either localized or generalized cerebral edema. The types of cerebral edema are vasogenic, cytotoxic, or interstitial. Increased capillary permeability causes vasogenic edema; this occurs with brain tumor, abscess, trauma, and hemorrhage. The fluid is loc ...
... Increased intracranial pressure results from either localized or generalized cerebral edema. The types of cerebral edema are vasogenic, cytotoxic, or interstitial. Increased capillary permeability causes vasogenic edema; this occurs with brain tumor, abscess, trauma, and hemorrhage. The fluid is loc ...
Slide 1 – Bakersfield College
... Drugs suggest a role for serotonin and GABA Amygdala, due to its role in fear and defensive behavior, thought to be involved No pathology yet identified Difficult to study neural basis of anxiety Diversity and subtlety of symptoms Abnormal breathing in anxious patients complicates functional b ...
... Drugs suggest a role for serotonin and GABA Amygdala, due to its role in fear and defensive behavior, thought to be involved No pathology yet identified Difficult to study neural basis of anxiety Diversity and subtlety of symptoms Abnormal breathing in anxious patients complicates functional b ...
Mitochondrial neurogastrointestinal encephalomyopathy: imaging
... with subcortical infarcts and leukoencephalopathy (CADASIL), Krabbe disease, and Canavan’s disease have similar symptoms on brain MRI. Symmetric white matter abnormalities can occur in toxic encephalophathies (2, 4). MRI findings may show abnormally increased T2-weighted signal intensities in the pe ...
... with subcortical infarcts and leukoencephalopathy (CADASIL), Krabbe disease, and Canavan’s disease have similar symptoms on brain MRI. Symmetric white matter abnormalities can occur in toxic encephalophathies (2, 4). MRI findings may show abnormally increased T2-weighted signal intensities in the pe ...
Neurology Ch. 65 - Porterville College
... • What nursing diagnosis would be priority for a patient with Parkinson’s? • Describe the muscle tone of a patient with Parkinson’s (medical terms) • What interventions can be used to address the issue of nonintention tremors? ...
... • What nursing diagnosis would be priority for a patient with Parkinson’s? • Describe the muscle tone of a patient with Parkinson’s (medical terms) • What interventions can be used to address the issue of nonintention tremors? ...
Variations in Muscle Tone - Down Syndrome of Louisville
... high (tension athetosis) or too low (choreo athetosis). Dystonia means abnormal tone. Most abnormal muscle tone caused by brain injury is of this “mixed” type. Tone is influenced by body positions; in dystonia, tone may be too high in some positions and too low in others. Sometimes tone is low in th ...
... high (tension athetosis) or too low (choreo athetosis). Dystonia means abnormal tone. Most abnormal muscle tone caused by brain injury is of this “mixed” type. Tone is influenced by body positions; in dystonia, tone may be too high in some positions and too low in others. Sometimes tone is low in th ...
Mild TBI causes a long-lasting elevation of the
... • The similar results of the symptomatic and recovered groups imply that simple MT by itself is not sufficient as a measure of injury severity or outcome, but it can be useful in combination with other methods. • It is noteworthy that also fully recovered mTBI subjects show an abnormal MT, which sug ...
... • The similar results of the symptomatic and recovered groups imply that simple MT by itself is not sufficient as a measure of injury severity or outcome, but it can be useful in combination with other methods. • It is noteworthy that also fully recovered mTBI subjects show an abnormal MT, which sug ...
The temporal lobe is a target of output from the basal ganglia
... DIRECT, the direct pathway through the basal ganglia; E, enkephalin-positive projection; GPe, external segment of the globus pallidus; INDIRECT, the indirect pathway through the basal ganglia, that involves the STN; P, substance P-positive projection. ...
... DIRECT, the direct pathway through the basal ganglia; E, enkephalin-positive projection; GPe, external segment of the globus pallidus; INDIRECT, the indirect pathway through the basal ganglia, that involves the STN; P, substance P-positive projection. ...
Master Storyboard
... MRI imaging. This is done by lowering a test electrode into the brain that records neuron firing. The test electrode is not capable of electrical stimulation, but can read electrical signals throughout the brain. As the electrode is lowered past normal cells and then to the tremor cells, the electro ...
... MRI imaging. This is done by lowering a test electrode into the brain that records neuron firing. The test electrode is not capable of electrical stimulation, but can read electrical signals throughout the brain. As the electrode is lowered past normal cells and then to the tremor cells, the electro ...
Neurology (Ingram) - University of Mississippi Medical Center
... A 54 y/o man with Parkinson disease is brought by his wife, who is concerned about her husband’s recent excessive gambling. She says that in the past 6 mos, he has been spending increasing amounts of time at a casino, where he rarely enjoyed going before the diagnosis of Parkinson disease. His beha ...
... A 54 y/o man with Parkinson disease is brought by his wife, who is concerned about her husband’s recent excessive gambling. She says that in the past 6 mos, he has been spending increasing amounts of time at a casino, where he rarely enjoyed going before the diagnosis of Parkinson disease. His beha ...
MENNONITE COLLEGE OF NURSING AT ILLINOIS STATE
... Visual field defects Pupillary reactions (dilation, constriction, abnormal reactions to light) Ptosis Abnormal extraocular movements ...
... Visual field defects Pupillary reactions (dilation, constriction, abnormal reactions to light) Ptosis Abnormal extraocular movements ...
Life Raft for Neuroscience 2 Final Exam
... unpaid. Recently she is not taking usual care in dressing. The patient responded that he “was making mountains out of anthills.” The patient also thought that the house had been recently burglarized and that people were watching the house. Except for a long history for gout and an ulcer many years a ...
... unpaid. Recently she is not taking usual care in dressing. The patient responded that he “was making mountains out of anthills.” The patient also thought that the house had been recently burglarized and that people were watching the house. Except for a long history for gout and an ulcer many years a ...
- MATEC Web of Conferences
... Cerebral palsy is manifested in different ways, whether it is affecting the physical part as the intellectual part of the patient, or both simultaneously, depending on the features of disabilities, to cerebral palsy can classify it from different points of view, in various bibliographic materials ar ...
... Cerebral palsy is manifested in different ways, whether it is affecting the physical part as the intellectual part of the patient, or both simultaneously, depending on the features of disabilities, to cerebral palsy can classify it from different points of view, in various bibliographic materials ar ...
Medical Terms in Prion Disease
... muscle tone and truncal stability through the basal ganglia; injuries to this system can cause movement disorders, inability to initiate movement and/or inability to remain motionless fatal familial insomnia (FFI): Fatal familial insomnia (FFI) is a very rare autosomal dominant inherited disease of ...
... muscle tone and truncal stability through the basal ganglia; injuries to this system can cause movement disorders, inability to initiate movement and/or inability to remain motionless fatal familial insomnia (FFI): Fatal familial insomnia (FFI) is a very rare autosomal dominant inherited disease of ...
degenerative diseases module
... 1. Degenerative diseases characterized primarily by cerebral cortex lesions: For each of the following diseases, describe (as appropriate) etiology/pathogenesis of lesions, location of lesions, clinical features and course of the disease, diagnostic tests, inheritance pattern and genetic mechanism, ...
... 1. Degenerative diseases characterized primarily by cerebral cortex lesions: For each of the following diseases, describe (as appropriate) etiology/pathogenesis of lesions, location of lesions, clinical features and course of the disease, diagnostic tests, inheritance pattern and genetic mechanism, ...
Hyperkinesia
Hyperkinesia, also known as hyperkinesis, refers to an increase in muscular activity that can result in excessive abnormal movements, excessive normal movements, or a combination of both. The word hyperkinesis comes from the Greek hyper, meaning ""increased,"" and kinein, meaning ""to move."" Hyperkinesia is a state of excessive restlessness which is featured in a large variety of disorders that affect the ability to control motor movement, such as Huntington's disease. It is the opposite of hypokinesia, which refers to decreased bodily movement, as commonly manifested in Parkinson's disease. Many hyperkinetic movements are the result of improper regulation of the basal ganglia-thalamocortical circuitry. Overactivity of a direct pathway combined with decreased activity of an indirect pathway results in activation of thalamic neurons and excitation of cortical neurons, resulting in increased motor output. Often, hyperkinesia is paired with hypotonia, a decrease in muscle tone. Many hyperkinetic disorders are psychological in nature and are typically prominent in childhood. Depending on the specific type of hyperkinetic movement, there are different treatment options available to minimize the symptoms, including different medical and surgical therapies.