Prescribing Information
... R-enantiomer of modafinil). Although the pharmacology of modafinil is not identical to that of the sympathomimetic amines, it does share some pharmacologic properties with this class. Certain of these drugs have been associated with intrauterine growth restriction and spontaneous abortions. Whether ...
... R-enantiomer of modafinil). Although the pharmacology of modafinil is not identical to that of the sympathomimetic amines, it does share some pharmacologic properties with this class. Certain of these drugs have been associated with intrauterine growth restriction and spontaneous abortions. Whether ...
Lupaneta Pack
... because of the physiologic effect of the drug. Therefore, an increase in symptoms associated with endometriosis may be observed during the initial days of therapy, but these should dissipate with continued therapy. 5.8 Fluid Retention Because norethindrone acetate may cause some degree of fluid rete ...
... because of the physiologic effect of the drug. Therefore, an increase in symptoms associated with endometriosis may be observed during the initial days of therapy, but these should dissipate with continued therapy. 5.8 Fluid Retention Because norethindrone acetate may cause some degree of fluid rete ...
L-Carnitine Monograph - Alternative Medicine Review
... Synthesis of carnitine begins with methylation of the amino acid L-lysine by S-adenosylmethionine (SAMe). Magnesium, vitamin C, iron, vitamins B3 and B6, and alpha-ketoglutarate – along with the cofactors responsible for creating SAMe (methionine, folic acid, vitamin B12, and betaine) – are all requ ...
... Synthesis of carnitine begins with methylation of the amino acid L-lysine by S-adenosylmethionine (SAMe). Magnesium, vitamin C, iron, vitamins B3 and B6, and alpha-ketoglutarate – along with the cofactors responsible for creating SAMe (methionine, folic acid, vitamin B12, and betaine) – are all requ ...
BOTOX COSMETIC
... administration in pregnant women. Studies in animals have shown reproductive toxicity. The potential risk for humans is unknown. BOTOX COSMETIC® should not be used during pregnancy. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should b ...
... administration in pregnant women. Studies in animals have shown reproductive toxicity. The potential risk for humans is unknown. BOTOX COSMETIC® should not be used during pregnancy. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should b ...
Therapeutic and pharmacological potential of Foeniculum vulgare Mill
... treating diseases (1,2). Nowadays medicinal herbs are good alternative to chemical drugs, one of the major reason for this is low side effect compared to chemical drugs (3,4). Plants have always played an important role in the health and treatment of human society (5). Medicinal herbs have fewer sid ...
... treating diseases (1,2). Nowadays medicinal herbs are good alternative to chemical drugs, one of the major reason for this is low side effect compared to chemical drugs (3,4). Plants have always played an important role in the health and treatment of human society (5). Medicinal herbs have fewer sid ...
product monograph isoptin sr
... not seen in a second study.) No similar changes have been observed in long-term prospective human ophthalmological trials. Renal Renal Insufficiency About 70% of an administered dose of verapamil hydrochloride is excreted as metabolites in the urine. In one study in healthy volunteers, the total bod ...
... not seen in a second study.) No similar changes have been observed in long-term prospective human ophthalmological trials. Renal Renal Insufficiency About 70% of an administered dose of verapamil hydrochloride is excreted as metabolites in the urine. In one study in healthy volunteers, the total bod ...
PRODUCT MONOGRAPH PrDEPO-MEDROL* WITH LIDOCAINE
... Literature reports suggest an apparent association between the use of corticosteroids and left ventricular free wall rupture after a recent myocardial infarction; therefore, therapy with corticosteroids should be used with great caution in these patients. As sodium retention with resultant edema and ...
... Literature reports suggest an apparent association between the use of corticosteroids and left ventricular free wall rupture after a recent myocardial infarction; therefore, therapy with corticosteroids should be used with great caution in these patients. As sodium retention with resultant edema and ...
LUPANETA PACK
... because of the physiologic effect of the drug. Therefore, an increase in symptoms associated with endometriosis may be observed during the initial days of therapy, but these should dissipate with continued therapy. 5.8 Fluid Retention Because norethindrone acetate may cause some degree of fluid rete ...
... because of the physiologic effect of the drug. Therefore, an increase in symptoms associated with endometriosis may be observed during the initial days of therapy, but these should dissipate with continued therapy. 5.8 Fluid Retention Because norethindrone acetate may cause some degree of fluid rete ...
Martindale: The Complete Drug Reference
... Date of monograph revision: 15-Sep-1997; 15-Jul-1998; 09-Mar-2000; 06-Nov-2001; 20-Aug-2003; 31-May-2006; 22-Nov-2007; 10-Sep-2008; ...
... Date of monograph revision: 15-Sep-1997; 15-Jul-1998; 09-Mar-2000; 06-Nov-2001; 20-Aug-2003; 31-May-2006; 22-Nov-2007; 10-Sep-2008; ...
Stability considerations in liquid dosage forms extemporaneously
... who are unable to swallow solid dosage forms such as tablets or capsules; (iii) patients who must receive medications via nasogastric or gastrostomy tubes; and (iv) patients who require non-standard doses that are more easily and accurately measured by using a liquid formulation (1-10). It is common ...
... who are unable to swallow solid dosage forms such as tablets or capsules; (iii) patients who must receive medications via nasogastric or gastrostomy tubes; and (iv) patients who require non-standard doses that are more easily and accurately measured by using a liquid formulation (1-10). It is common ...
ENCLOSURE 1
... analysis of the combined data from grapefruit and orange juices studies with the data from a bioequivalence study, the bioavailability' of fexofenadine was reduced by 36%. Therefore, to maximize the effects of fexofenadine, it is recommended that fexofenadine hydrochloride should be taken with water ...
... analysis of the combined data from grapefruit and orange juices studies with the data from a bioequivalence study, the bioavailability' of fexofenadine was reduced by 36%. Therefore, to maximize the effects of fexofenadine, it is recommended that fexofenadine hydrochloride should be taken with water ...
Oxycodone - Thblack.com
... active metabolite of oxycodone, has a significantly higher µ-opioid receptor binding affinity. Intramuscular oxymorphone and morphine were compared in patients with chronic pain due to cancer. Intramuscular oxymorphone proved to be 8.7 times as potent as morphine in terms of total analgesic effect a ...
... active metabolite of oxycodone, has a significantly higher µ-opioid receptor binding affinity. Intramuscular oxymorphone and morphine were compared in patients with chronic pain due to cancer. Intramuscular oxymorphone proved to be 8.7 times as potent as morphine in terms of total analgesic effect a ...
2nd Quarter Conference Call
... Eligen® B12 – Summary All research indicates that Eligen® B12 presents a significant improvement to help approach the problem of B12 supplementation, regardless of level of supplementation that may be required Emisphere is committed to commercializing Eligen® B12 as an opportunity for all defin ...
... Eligen® B12 – Summary All research indicates that Eligen® B12 presents a significant improvement to help approach the problem of B12 supplementation, regardless of level of supplementation that may be required Emisphere is committed to commercializing Eligen® B12 as an opportunity for all defin ...
The effective study of aqueous extract of Crocus sativus Linn
... Company, were analyzed by using an HPLC photodiode array detection method. This analysis quantified the 10 major saffron compounds in each sample and their concentration was analyzed at three different wavelengths. Result indicated that the Greek Indian, New Zealand, and Spanish saffron extracts pos ...
... Company, were analyzed by using an HPLC photodiode array detection method. This analysis quantified the 10 major saffron compounds in each sample and their concentration was analyzed at three different wavelengths. Result indicated that the Greek Indian, New Zealand, and Spanish saffron extracts pos ...
PRODUCT MONOGRAPH Cipralex Escitalopram Oxalate
... (suicide-related events). This risk persists until significant remission occurs. As improvement may not occur during the first few weeks or more of treatment, patients should be closely monitored until such improvement occurs. It is general clinical experience that the risk of suicide may increase i ...
... (suicide-related events). This risk persists until significant remission occurs. As improvement may not occur during the first few weeks or more of treatment, patients should be closely monitored until such improvement occurs. It is general clinical experience that the risk of suicide may increase i ...
London 2012 Paralympic Games Pharmacy Guide
... including the specific requirements for controlled drugs, is contained in the London 2012 Customs and Freight Forwarding Guide. The guide may be accessed through The Exchange, LOCOG’s secure extranet for NPCs, at https://theexchange.london2012.com. In most situations, UK medicines legislation does n ...
... including the specific requirements for controlled drugs, is contained in the London 2012 Customs and Freight Forwarding Guide. The guide may be accessed through The Exchange, LOCOG’s secure extranet for NPCs, at https://theexchange.london2012.com. In most situations, UK medicines legislation does n ...
FLUOROQUINOLONES - American Academy of Veterinary
... mutation (gyr-A). Less commonly, but perhaps more importantly for gram-positive bacteria, mutation occurs at the topoisomeraseIV target (parC).{R-9; 21; 86} Other mechanisms of resistance occur when bacteria decrease the ability of the drug to enter the cell or increase active transport out of the c ...
... mutation (gyr-A). Less commonly, but perhaps more importantly for gram-positive bacteria, mutation occurs at the topoisomeraseIV target (parC).{R-9; 21; 86} Other mechanisms of resistance occur when bacteria decrease the ability of the drug to enter the cell or increase active transport out of the c ...
Prescribing Information - PI
... three times daily have been administered. 1. Most patients heal within 4 weeks; some patients may require an additional 4 weeks of therapy to achieve healing 2. The efficacy of PRILOSEC used for longer than 8 weeks in patients with EE has not been established. If a patient does not respond to 8 week ...
... three times daily have been administered. 1. Most patients heal within 4 weeks; some patients may require an additional 4 weeks of therapy to achieve healing 2. The efficacy of PRILOSEC used for longer than 8 weeks in patients with EE has not been established. If a patient does not respond to 8 week ...
annexure – ii
... antibacterial, hepatoprotective etc. It is also known that process of inflammation has been shown to play a major role in most chronic illnesses, including neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases thus curcumin is also used in the treatment of these ...
... antibacterial, hepatoprotective etc. It is also known that process of inflammation has been shown to play a major role in most chronic illnesses, including neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases thus curcumin is also used in the treatment of these ...
Ceftriaxone-AFT
... reported with virtually all broad-spectrum antibiotics. It is important to consider this diagnosis in patients who develop diarrhoea in association with the use of ceftriaxone. Drugs which delay peristalsis may prolong and/or worsen the condition and should not be used. Prothrombin time-Prolonged pr ...
... reported with virtually all broad-spectrum antibiotics. It is important to consider this diagnosis in patients who develop diarrhoea in association with the use of ceftriaxone. Drugs which delay peristalsis may prolong and/or worsen the condition and should not be used. Prothrombin time-Prolonged pr ...
Activated Charcoal - Paramedic Advantage
... Adult: 2.5 mg in 3cc NS (0.5% solution) over 5-15 minutes utilizing 6-8 LPM of oxygen, prn (for hyperkalemia: 10-20mg over 15 minutes) Pediatric: 0.1 – 0.3 mg/kg of a 0.5% solution, prn LA Co: Respiratory - 5 mg in 3 cc of NS with hand held nebulizer/mask over 5-15 minutes, repeat as needed. Crush S ...
... Adult: 2.5 mg in 3cc NS (0.5% solution) over 5-15 minutes utilizing 6-8 LPM of oxygen, prn (for hyperkalemia: 10-20mg over 15 minutes) Pediatric: 0.1 – 0.3 mg/kg of a 0.5% solution, prn LA Co: Respiratory - 5 mg in 3 cc of NS with hand held nebulizer/mask over 5-15 minutes, repeat as needed. Crush S ...
Title
... water tail flick and formalin pain tests. The extract (100-400mg/kg) and acetylsalicylic acid (100mg/kg) produced significant (P<0.05) inhibition of the second phase response in the formalin pain model, while only the high dose (400mg/kg) of the extract showed an antinociceptive effect in the first ...
... water tail flick and formalin pain tests. The extract (100-400mg/kg) and acetylsalicylic acid (100mg/kg) produced significant (P<0.05) inhibition of the second phase response in the formalin pain model, while only the high dose (400mg/kg) of the extract showed an antinociceptive effect in the first ...
overview of comments received on community - EMA
... For several of the extracts mentioned above, published data do not support a lower limit of hyperforin of 2 %. This applies to the extracts C) and G), as documented in the publications of Melzer et al. 1998, Wurglics et al. 2001a, Wurglics et al. 2001b, Volz and Zeller 2000) which mention hyperforin ...
... For several of the extracts mentioned above, published data do not support a lower limit of hyperforin of 2 %. This applies to the extracts C) and G), as documented in the publications of Melzer et al. 1998, Wurglics et al. 2001a, Wurglics et al. 2001b, Volz and Zeller 2000) which mention hyperforin ...
LOSARTAN POTASSIUM AMLODIPINE CAMSYLATE
... the effects of 20 mg and 100 mg of losartan potassium and an ACE inhibitor on responses to angiotensin I, angiotensin II and bradykinin, losartan was shown to block responses to angiotensin I and angiotensin II without affecting responses to bradykinin. This finding is consistent with losartan’s spe ...
... the effects of 20 mg and 100 mg of losartan potassium and an ACE inhibitor on responses to angiotensin I, angiotensin II and bradykinin, losartan was shown to block responses to angiotensin I and angiotensin II without affecting responses to bradykinin. This finding is consistent with losartan’s spe ...
Pharmacologically Active Drug Metabolites: Impact on Drug
... 12. Levosimendan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 612 13. Metoprolol . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...
... 12. Levosimendan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 612 13. Metoprolol . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...
Dydrogesterone
Dydrogesterone (INN, USAN, BAN), is also chemically known as 9β,10α-pregna-4,6-diene-3,20-dione. Dydrogesterone (6-dehydro-retroprogesterone) is a hormonally active, non-androgenic steroid that was developed in the 1950s.Dydrogesterone has selective progestational activity and does not inhibit ovulation. The greater rigidity of dydrogesterone also positively affects its selectivity, while natural progesterone is less selective, existing in different conformations that more easily bind to different receptors. As a consequence of its better bioavailability and the progestational activity of its main metabolites (20-, 21- and 16-hydroxy derivatives), the equivalent dose of dydrogesterone is 10–20 times lower than that of oral micronized progesterone.Dydrogesterone is used as an effective, orally active progestogen for gynaecological conditions related to a wide variety of progesterone deficiencies in pregnant women. The molecular structure and pharmacological effects are somewhat similar to endogenous progesterone, although in smaller amounts it is found to be orally active. Its freedom from hormonal effects like those related to corticoid, androgenic, estrogenic, anabolic, and other effects gives dydrogesterone an advantage over other synthesized progestogens.Dydrogesterone when used therapeutically is closely related to its physiological action on the neuro-endocrine control of ovarian function, as well as on the endometrium. This is an indication in all cases of endogeneous progesterone deficiency - relative or absolute. The molecule was licensed for use in several indications, including threatened or recurrent miscarriage, dysfunctional bleeding, infertility due to luteal insufficiency, dysmenorrhea, endometriosis, secondary amenorrhoea, irregular cycles, pre-menstrual syndrome and also as a hormone replacement therapy.Dydrogesterone has proven effective in the following conditions associated with progesterone deficiency: Infertility due to luteal insufficiency Threatened miscarriage Habitual or recurrent miscarriage. Menstrual disorders Premenstrual syndrome Endometriosis Dydrogesterone has also been registered as hormone replacement therapy (HRT) to counter-check the negative effects of unopposed estrogen on the endometrium in women with an intact uterus. Dydrogesterone is relatively safe and well tolerated, and does not exhibit the androgenic side effects that are common with some other progestins, like medroxyprogesterone acetate.