BHF Factfile: The Use of Digoxin
... randomized trial, showed that digoxin had no effect on mortality and only led to a small reduction in the number of hospital admissions. Since digoxin is hard to use without avoiding toxicity, its minimal efficacy in heart failure in sinus rhythm does not justify its use as a first-line drug. It sho ...
... randomized trial, showed that digoxin had no effect on mortality and only led to a small reduction in the number of hospital admissions. Since digoxin is hard to use without avoiding toxicity, its minimal efficacy in heart failure in sinus rhythm does not justify its use as a first-line drug. It sho ...
الشريحة 1
... disorder. Several NSAIDs (including aspirin) appear to reduce the incidence of colon cancer when taken chronically. Several large epidemiologic studies have shown a 50% reduction in relative risk when the drugs are taken for 5 years or longer. The mechanism for this protective effect is unclear. ...
... disorder. Several NSAIDs (including aspirin) appear to reduce the incidence of colon cancer when taken chronically. Several large epidemiologic studies have shown a 50% reduction in relative risk when the drugs are taken for 5 years or longer. The mechanism for this protective effect is unclear. ...
Preliminary, Open-Label, Pilot Study of Add-On Oral D
... Many patients with post-traumatic stress disorder (PTSD) do not achieve remission with currently available treatment [1] and some turn to alcohol and substance abuse [2]. Among other substances, marijuana is often used to alleviate PTSD symptoms of avoidance/numbing and hyperarousal [2]. Following r ...
... Many patients with post-traumatic stress disorder (PTSD) do not achieve remission with currently available treatment [1] and some turn to alcohol and substance abuse [2]. Among other substances, marijuana is often used to alleviate PTSD symptoms of avoidance/numbing and hyperarousal [2]. Following r ...
R Sams - National Thoroughbred Racing Association
... Samples are checked for adherence to furosemide dosing restrictions – evidence for compliance is good Adjunct medications are readily detected and do not interfere with test procedures ...
... Samples are checked for adherence to furosemide dosing restrictions – evidence for compliance is good Adjunct medications are readily detected and do not interfere with test procedures ...
Current Therapy in Ocular Disease -The Vision Institute of Canada-
... • Either animal studies show risk, human studies do not; or if no human studies, animal studies negative • C- Risk cannot be ruled out. • Human studies lacking, and animal studies positive for fetal risk or lacking. Potential benefits may justify potential risks • D- Positive evidence of risk post-m ...
... • Either animal studies show risk, human studies do not; or if no human studies, animal studies negative • C- Risk cannot be ruled out. • Human studies lacking, and animal studies positive for fetal risk or lacking. Potential benefits may justify potential risks • D- Positive evidence of risk post-m ...
voltaren - GuildLink
... in general have more serious consequences in the elderly. They can occur at any time during treatment with or without warning symptoms or a previous history. In instances where gastrointestinal bleeding or ulcerations occur in patients receiving Voltaren, the drug should be withdrawn immediately. Ph ...
... in general have more serious consequences in the elderly. They can occur at any time during treatment with or without warning symptoms or a previous history. In instances where gastrointestinal bleeding or ulcerations occur in patients receiving Voltaren, the drug should be withdrawn immediately. Ph ...
Conversions of Strong Opiates
... Useful in renal failure Compliance Slow to titrate Not good for acute or unstable pain ...
... Useful in renal failure Compliance Slow to titrate Not good for acute or unstable pain ...
(Oxycodone HCl and Ibuprofen) Tablets FOREST LABORATORIES CII Rx only
... Combunox was investigated in three clinical studies. Two studies involving a total of 949 patients following dental surgery (removal of ipsilateral molars) and a third study of 456 patients following abdominal/pelvic surgery were conducted. In the three studies patients were administered a single do ...
... Combunox was investigated in three clinical studies. Two studies involving a total of 949 patients following dental surgery (removal of ipsilateral molars) and a third study of 456 patients following abdominal/pelvic surgery were conducted. In the three studies patients were administered a single do ...
Lansoprazole/C02-039 A Phase 2, Open-Label Multicenter
... without prior approval from the sponsor. Patients should consult their health care professional for advice about their specific situation. ...
... without prior approval from the sponsor. Patients should consult their health care professional for advice about their specific situation. ...
Caffeine Drug Protocol
... IV: Infuse loading dose over at least 30 minutes and maintenance over 10 minutes. ORAL: Solution may be administered without regard to feeds, however consider giving with feeds to reduce gastric irritation. ...
... IV: Infuse loading dose over at least 30 minutes and maintenance over 10 minutes. ORAL: Solution may be administered without regard to feeds, however consider giving with feeds to reduce gastric irritation. ...
RESTLESS LEG SYNDROME
... dose was 0.25 mg PO daily, doubling Q5days for the first 2 weeks until symptom relief, then up to a maximum of 2 mg/day (mean dose was 1.45 mg/day). Levodopa SR dose was 100/25 mg PO daily, then doubling after 2 weeks until symptom relief (mean levodopa dose 190 mg/day). Vomiting reported in one lev ...
... dose was 0.25 mg PO daily, doubling Q5days for the first 2 weeks until symptom relief, then up to a maximum of 2 mg/day (mean dose was 1.45 mg/day). Levodopa SR dose was 100/25 mg PO daily, then doubling after 2 weeks until symptom relief (mean levodopa dose 190 mg/day). Vomiting reported in one lev ...
Opioid Dosing - San Francisco Health Plan
... Start with lower methadone doses for older patients, those with renal, liver or lung disease, or those on high doses of opiates. ...
... Start with lower methadone doses for older patients, those with renal, liver or lung disease, or those on high doses of opiates. ...
Phase I and Pharmacokinetic Study of Farnesyl Protein Transferase
... Table 1. The starting dose was 50 mg daily, less than 1/10th of the lethal dose in dogs. This conservative starting dose was chosen because of the wide interspecies variability in the bioavailability of R115777 (data on file) and the importance of the ras signal transduction pathway for normal cellu ...
... Table 1. The starting dose was 50 mg daily, less than 1/10th of the lethal dose in dogs. This conservative starting dose was chosen because of the wide interspecies variability in the bioavailability of R115777 (data on file) and the importance of the ras signal transduction pathway for normal cellu ...
Zyvox - Blue Cross Blue Shield of Arizona
... organisms. MRSA has become a common cause of ABSSSI infections and pneumonia in the hospital setting. Infections in individuals who lack the usual risk factors for MRSA have also emerged in the community. As a result, community associated MRSA (CA-MRSA) are now a common cause of ABSSSI. Over relianc ...
... organisms. MRSA has become a common cause of ABSSSI infections and pneumonia in the hospital setting. Infections in individuals who lack the usual risk factors for MRSA have also emerged in the community. As a result, community associated MRSA (CA-MRSA) are now a common cause of ABSSSI. Over relianc ...
voltaren - GuildLink
... in general have more serious consequences in the elderly. They can occur at any time during treatment with or without warning symptoms or a previous history. In instances where gastrointestinal bleeding or ulcerations occur in patients receiving Voltaren, the drug should be withdrawn immediately. Ph ...
... in general have more serious consequences in the elderly. They can occur at any time during treatment with or without warning symptoms or a previous history. In instances where gastrointestinal bleeding or ulcerations occur in patients receiving Voltaren, the drug should be withdrawn immediately. Ph ...
Summary of RLS treatment recommendations FINAL
... lower than 75 μg/mL, supplementation with orally administered iron is recommended unless poorly tolerated or contraindicated. ...
... lower than 75 μg/mL, supplementation with orally administered iron is recommended unless poorly tolerated or contraindicated. ...
Ipratropium use in COPD
... - Inhalation solutions for nebulization should be protected from light - solutions containing ipratropium bromide stable for 1 hour when mixed in a nebulizer prior to administration. ...
... - Inhalation solutions for nebulization should be protected from light - solutions containing ipratropium bromide stable for 1 hour when mixed in a nebulizer prior to administration. ...
Guideline on the management of bleeding in patients on
... ratios of anti-Xa to anti-IIa activities vary between products depending on LMWH chain length. However the half-life of the anticoagulant activity of LMWH lasts approximately 4 h. The mechanism of action of LMWH and differences from UFH were recently reviewed (Gray et al, 2008). LMWH activity may be ...
... ratios of anti-Xa to anti-IIa activities vary between products depending on LMWH chain length. However the half-life of the anticoagulant activity of LMWH lasts approximately 4 h. The mechanism of action of LMWH and differences from UFH were recently reviewed (Gray et al, 2008). LMWH activity may be ...
Remeron® Tablets 15 mg Remeron® Tablets 30 mg Remeron
... - When the depressive phase of bipolar disorder is being treated, it can transform into the manic phase. Patients with a history of mania/hypomania should be closely monitored. Mirtazapine should be discontinued in any patient entering a manic phase. - Although Remeron is not addictive, post-marketi ...
... - When the depressive phase of bipolar disorder is being treated, it can transform into the manic phase. Patients with a history of mania/hypomania should be closely monitored. Mirtazapine should be discontinued in any patient entering a manic phase. - Although Remeron is not addictive, post-marketi ...
Hypotension - Acorda Therapeutics
... Because clinical studies are conducted under widely varying conditions, adverse reaction rates observed in the clinical studies of a drug cannot be directly compared to rates in the clinical studies of another drug and may not reflect the rates observed in clinical practice. Three double-blind, rand ...
... Because clinical studies are conducted under widely varying conditions, adverse reaction rates observed in the clinical studies of a drug cannot be directly compared to rates in the clinical studies of another drug and may not reflect the rates observed in clinical practice. Three double-blind, rand ...
George Wells - International Society of Evidence
... – Orally administered – Do not require monitoring of the anticoagulant effect – Few drug interactions and no food interactions – Can be applied at a fixed dose; – Do not have an antidote in case of bleeding and need to discontinue the medication in an urgent situation ...
... – Orally administered – Do not require monitoring of the anticoagulant effect – Few drug interactions and no food interactions – Can be applied at a fixed dose; – Do not have an antidote in case of bleeding and need to discontinue the medication in an urgent situation ...
5 Intranasal Ciclesonide for Treatment of Allergic Rhinitis in Children
... In a 6-week study conducted in children 2 to 5 years of age, ciclesonide use was associated with a small decline in morning plasma cortisol values, with a mean change from baseline -0.12, 0.36, and -1.04 mcg/dL for the 25 mcg, 100 mcg, and 200 mcg doses, respectively. Additional long-term studies, u ...
... In a 6-week study conducted in children 2 to 5 years of age, ciclesonide use was associated with a small decline in morning plasma cortisol values, with a mean change from baseline -0.12, 0.36, and -1.04 mcg/dL for the 25 mcg, 100 mcg, and 200 mcg doses, respectively. Additional long-term studies, u ...
product monograph
... While syncope is the most severe orthostatic effect of CARDURA, other symptoms of lowered blood pressure such as dizziness, lightheadedness or vertigo can occur. These were common in clinical trials in hypertension, occurring in up to 23% of all patients treated and causing discontinuation of therap ...
... While syncope is the most severe orthostatic effect of CARDURA, other symptoms of lowered blood pressure such as dizziness, lightheadedness or vertigo can occur. These were common in clinical trials in hypertension, occurring in up to 23% of all patients treated and causing discontinuation of therap ...
ketorolac tromethamine utilization management criteria
... 1. Gastrointestinal effects: Ketorolac may cause peptic ulcers, GI bleeding and/or perforation. 2. Renal effects: Ketorolac is contraindicated in patients with advanced renal impairment and in patients at risk for renal failure due to volume depletion. 3. Risk of bleeding: Ketorolac inhibits platele ...
... 1. Gastrointestinal effects: Ketorolac may cause peptic ulcers, GI bleeding and/or perforation. 2. Renal effects: Ketorolac is contraindicated in patients with advanced renal impairment and in patients at risk for renal failure due to volume depletion. 3. Risk of bleeding: Ketorolac inhibits platele ...
Atropine Sulfate Ampoule Product Sheet (PDF
... Administration of this product under strict medical supervision. ...
... Administration of this product under strict medical supervision. ...
Dydrogesterone
Dydrogesterone (INN, USAN, BAN), is also chemically known as 9β,10α-pregna-4,6-diene-3,20-dione. Dydrogesterone (6-dehydro-retroprogesterone) is a hormonally active, non-androgenic steroid that was developed in the 1950s.Dydrogesterone has selective progestational activity and does not inhibit ovulation. The greater rigidity of dydrogesterone also positively affects its selectivity, while natural progesterone is less selective, existing in different conformations that more easily bind to different receptors. As a consequence of its better bioavailability and the progestational activity of its main metabolites (20-, 21- and 16-hydroxy derivatives), the equivalent dose of dydrogesterone is 10–20 times lower than that of oral micronized progesterone.Dydrogesterone is used as an effective, orally active progestogen for gynaecological conditions related to a wide variety of progesterone deficiencies in pregnant women. The molecular structure and pharmacological effects are somewhat similar to endogenous progesterone, although in smaller amounts it is found to be orally active. Its freedom from hormonal effects like those related to corticoid, androgenic, estrogenic, anabolic, and other effects gives dydrogesterone an advantage over other synthesized progestogens.Dydrogesterone when used therapeutically is closely related to its physiological action on the neuro-endocrine control of ovarian function, as well as on the endometrium. This is an indication in all cases of endogeneous progesterone deficiency - relative or absolute. The molecule was licensed for use in several indications, including threatened or recurrent miscarriage, dysfunctional bleeding, infertility due to luteal insufficiency, dysmenorrhea, endometriosis, secondary amenorrhoea, irregular cycles, pre-menstrual syndrome and also as a hormone replacement therapy.Dydrogesterone has proven effective in the following conditions associated with progesterone deficiency: Infertility due to luteal insufficiency Threatened miscarriage Habitual or recurrent miscarriage. Menstrual disorders Premenstrual syndrome Endometriosis Dydrogesterone has also been registered as hormone replacement therapy (HRT) to counter-check the negative effects of unopposed estrogen on the endometrium in women with an intact uterus. Dydrogesterone is relatively safe and well tolerated, and does not exhibit the androgenic side effects that are common with some other progestins, like medroxyprogesterone acetate.