Cytochrome P450 3A4: The Impossible Protein
... this situation the drugs will not be oxidized in the same way that they would be if there were only one bound to the protein. This makes it difficult to administer more than one drug at once because of the possible effects that occur due to 3A4. In addition to having this binding property, 3A4 is t ...
... this situation the drugs will not be oxidized in the same way that they would be if there were only one bound to the protein. This makes it difficult to administer more than one drug at once because of the possible effects that occur due to 3A4. In addition to having this binding property, 3A4 is t ...
Surveying Protein Structure and Function Using Bis
... xploration across the fields of biology, chemical biology, and medicine has led to an increasingly complex, albeit incomplete, view of the interactions that drive life's processes. The ability to monitor and track the movement, activity, and interactions of biomolecules in living cells is an essenti ...
... xploration across the fields of biology, chemical biology, and medicine has led to an increasingly complex, albeit incomplete, view of the interactions that drive life's processes. The ability to monitor and track the movement, activity, and interactions of biomolecules in living cells is an essenti ...
Important roles for novel protein phosphatases dephosphorylating
... contrast, cDNA for other protein phosphatases under the same promoter did not rescue sit4-102. Proof that PPV could perform all the in vivo functions of SIT4 came from the demonstration that PPV cDNA, when under the SIT4 promoter, could completely replace the S I T 4 gene in S. cerevisiae. The large ...
... contrast, cDNA for other protein phosphatases under the same promoter did not rescue sit4-102. Proof that PPV could perform all the in vivo functions of SIT4 came from the demonstration that PPV cDNA, when under the SIT4 promoter, could completely replace the S I T 4 gene in S. cerevisiae. The large ...
Cytochrome P450 3A4: The Impossible Protein
... this situation the drugs will not be oxidized in the same way that they would be if there were only one bound to the protein. This makes it difficult to administer more than one drug at once because of the possible effects that occur due to 3A4. In addition to having this binding property, 3A4 is t ...
... this situation the drugs will not be oxidized in the same way that they would be if there were only one bound to the protein. This makes it difficult to administer more than one drug at once because of the possible effects that occur due to 3A4. In addition to having this binding property, 3A4 is t ...
- computer science publication server
... from SwissProt not present in SCOP1 itself. The evaluation itself was only performed on pairs of SCOP1 sequences. Fig. 7 shows a very favorable performance of the method on this substantially larger data set. Again, we achieve a one-hundred percent speci city over a wide range of thresholds while ad ...
... from SwissProt not present in SCOP1 itself. The evaluation itself was only performed on pairs of SCOP1 sequences. Fig. 7 shows a very favorable performance of the method on this substantially larger data set. Again, we achieve a one-hundred percent speci city over a wide range of thresholds while ad ...
Whey to isolate - Proteinfactory
... “In comparison to other protein isolates, WPI has a distinct advantage in amino-acid profile because whey proteins are higher in essential amino acids, especially branched-chain and sulfur-containing amino acids,” says Bastain. “WPI customers should review the amino-acid profile of protein isolates ...
... “In comparison to other protein isolates, WPI has a distinct advantage in amino-acid profile because whey proteins are higher in essential amino acids, especially branched-chain and sulfur-containing amino acids,” says Bastain. “WPI customers should review the amino-acid profile of protein isolates ...
Leukaemia Section t(9;22)(q34;q11) in ALL Atlas of Genetics and Cytogenetics
... DNA / RNA Various splicings. Protein Main form: 160 kDa; N-term Serine-Threonine kinase domain, SH2 binding, and C-term domain which functions as a GTPase activating protein for p21rac; widely expressed; cytoplasmic localisation; protein kinase; probable role in signal transduction. ...
... DNA / RNA Various splicings. Protein Main form: 160 kDa; N-term Serine-Threonine kinase domain, SH2 binding, and C-term domain which functions as a GTPase activating protein for p21rac; widely expressed; cytoplasmic localisation; protein kinase; probable role in signal transduction. ...
Polyclonal Antibodies to Lamins - Edinburgh Research and Innovation
... immunofluorescence applications. Lamins are membrane proteins that provide a structural framework for the nucleus and are also essential for maintaining normal cell functions, such as cell cycle control, DNA replication and chromatin organization. Mutations in the genes encoding nuclear Lamins a ...
... immunofluorescence applications. Lamins are membrane proteins that provide a structural framework for the nucleus and are also essential for maintaining normal cell functions, such as cell cycle control, DNA replication and chromatin organization. Mutations in the genes encoding nuclear Lamins a ...
Crystal Structures of Two Viral IRES RNA Domains Bound to the
... synthesize their viral proteins. During viral infections, host cells down-regulate capdependent initiation as a defense, but some viruses utilize a structural feature in their RNA called an internal ribosome entry site (IRES) to bypass the requirement for a capped structure and for some of the initi ...
... synthesize their viral proteins. During viral infections, host cells down-regulate capdependent initiation as a defense, but some viruses utilize a structural feature in their RNA called an internal ribosome entry site (IRES) to bypass the requirement for a capped structure and for some of the initi ...
Leishmania Flagellum
... Bin/Amphiphysin/Rvs (BAR) domains are 200-amino-acid modular elements found in many eukaryotic multi-domain proteins [14]. Although their amino acid sequence may be poorly conserved and therefore difficult to identify, their structure is well conserved throughout evolution [15]. The archetype BAR do ...
... Bin/Amphiphysin/Rvs (BAR) domains are 200-amino-acid modular elements found in many eukaryotic multi-domain proteins [14]. Although their amino acid sequence may be poorly conserved and therefore difficult to identify, their structure is well conserved throughout evolution [15]. The archetype BAR do ...
IOSR Journal Of Environmental Science, Toxicology And Food Technology (IOSR-JESTFT)
... like rice, wheat, ragi (Finger Millet) and oats was chosen. All the food stuffs were locally available, less expensive and also nutritive. Soy protein is considered nutritional equivalent of meat, eggs, and casein for human growth and health. The US Food and Drug Administration, propagates soy prote ...
... like rice, wheat, ragi (Finger Millet) and oats was chosen. All the food stuffs were locally available, less expensive and also nutritive. Soy protein is considered nutritional equivalent of meat, eggs, and casein for human growth and health. The US Food and Drug Administration, propagates soy prote ...
Parallel Geometric Hashing Algorithm for Protein Tertiary Structure
... classification and structure alignment [2]. In this paper, we ...
... classification and structure alignment [2]. In this paper, we ...
Labeling Proteins with Small Molecules by Site
... that were expressed as intein fusions. The intein domain was subsequently replaced by a small-molecule cysteine conjugate upon elution from a chitin column.3 Similarly, human O6-alkylguanine-DNA alkyltransferase (hGAT) has been used for site-specific protein labeling by irreversibly transferring the ...
... that were expressed as intein fusions. The intein domain was subsequently replaced by a small-molecule cysteine conjugate upon elution from a chitin column.3 Similarly, human O6-alkylguanine-DNA alkyltransferase (hGAT) has been used for site-specific protein labeling by irreversibly transferring the ...
Poster
... According to the American Cancer Society, one in eight U.S. women will develop breast cancer in their lifetime. Strikingly, many of these women share a significant genetic commonality. It has been shown that many breast cancer patients test positive for high levels of Estrogen Receptor (ERa), a prot ...
... According to the American Cancer Society, one in eight U.S. women will develop breast cancer in their lifetime. Strikingly, many of these women share a significant genetic commonality. It has been shown that many breast cancer patients test positive for high levels of Estrogen Receptor (ERa), a prot ...
1. Inter-chain disulfide bonds
... Both ends of support medium is immersed in alkaline buffer (pH 8.6), so proteins in this pH will be negatively charged. ...
... Both ends of support medium is immersed in alkaline buffer (pH 8.6), so proteins in this pH will be negatively charged. ...
Definition of Protein Superfamily
... the published literature to refer to a group of structurally or functionally related proteins not necessarily of common evolutionary origin. The term domain has been employed in the Protein Sequence Database to mean a region of special biological interest within a single protein chain. This term als ...
... the published literature to refer to a group of structurally or functionally related proteins not necessarily of common evolutionary origin. The term domain has been employed in the Protein Sequence Database to mean a region of special biological interest within a single protein chain. This term als ...
Protein domain
A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain. Each domain forms a compact three-dimensional structure and often can be independently stable and folded. Many proteins consist of several structural domains. One domain may appear in a variety of different proteins. Molecular evolution uses domains as building blocks and these may be recombined in different arrangements to create proteins with different functions. Domains vary in length from between about 25 amino acids up to 500 amino acids in length. The shortest domains such as zinc fingers are stabilized by metal ions or disulfide bridges. Domains often form functional units, such as the calcium-binding EF hand domain of calmodulin. Because they are independently stable, domains can be ""swapped"" by genetic engineering between one protein and another to make chimeric proteins.