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DNA
DNA

... Explain how a mutation can cause variation (limited to changes in the protein formed, which can affect processes in which that protein is needed). Give examples of mutations in human genes that affect the phenotype, and examples of those that have little or no obvious ...
Ch12b_Heredity
Ch12b_Heredity

... Nondisjunction of the sex chromosomes is more often survivable than nondisjunctions of somatic chromosomes. As long as the fetus has at least one X chromosome, it can survive. ...
Chapter 29 DNA as the Genetic Material Recombination of DNA
Chapter 29 DNA as the Genetic Material Recombination of DNA

... • Nitrous acid (oxidative deamination) • Fig 29.28a ...
Mutation and DNA Repair
Mutation and DNA Repair

... the “p” is the connecting phosphate) gets methylated: a CH3 group is attached to the 5 position on the ring. When 5-methyl cytosine is spontaneously deaminated, it is converted to thymine, a standard DNA base. Replication leads to a base change: one daughter stays a C-G base pair while the other is ...
Chromosomal Basis of Inheritance
Chromosomal Basis of Inheritance

... – 2. Chromosomes are replicated and passed along from parent to offspring – 3. The nuclei of most eukaryotic cells contain chromosomes that are found in homologous pairs " During meiosis, each homologue segregates into one of the two ...
Chapter 14
Chapter 14

... factor was discovered in. • The positive allele (Rh+) is dominant, meaning people who are Rh+/Rh+ or Rh+/Rh- are Rh-positive. • People with two Rh- alleles are Rh- negative. ...
Genome Analysis
Genome Analysis

... Complexity apparent in metazoans is not achieved by sheer number of genes Despite the large differences between fly and worm in terms of development and morphology, they use a core proteome of similar size  Comparative analysis of the predicted proteins encoded by these genomes suggests that near ...
Methods to analyze RNA expression - RNA
Methods to analyze RNA expression - RNA

... The short reads are aligned on the reference genome if available 2) The transcript(s) from each gene are reconstructed. At that point the analysis is done with all the libraries together looking at 3) differential expression and statistical significance. ...
article 4
article 4

... their present functional differences that are expressed at Beta hemoglobin gene cluster as it occurs different stages of embryonic, fetal, and adult developin primates. ment. The times at which the various hemoglobin duplications occurred are shown in Figure 2B. Of particular The pseudogene eta (ψη) ...
Notes for The Longevity Seekers
Notes for The Longevity Seekers

... life spans, to see if aging was regulated in a controlled or a haphazard way. Tabtiang used a daf-2 hibernation gene mutant as a control group and discovered that it lived twice as long as normal worms. Another gene, daf-16, superintended the process of lengthening life. Although other researchers w ...
$doc.title

Genetics PowerPoint
Genetics PowerPoint

... trait is controlled by a “factor” 2 or more “factors” for each trait •Dominant-more powerful, always shows (R) •Recessive-weaker, sometimes shows (r) ...
Genetics Powerpoint
Genetics Powerpoint

... Genetic Concepts ...
chromosome - Rossignols.net
chromosome - Rossignols.net

... How many chromosomes do human cells have? How many pairs of chromosomes do human cells have? What are somatic cells? You have one gene for blue eyes and one gene for brown eyes. – Where did these genes come from? – What are the 2 forms of this gene called? What does diploid mean? What are the two ha ...
• Double helix -- twisted ladder shape of DNA, like spiral staircase
• Double helix -- twisted ladder shape of DNA, like spiral staircase

... Which letters bind with which? A - T, G - C ...
Genscope Project
Genscope Project

... models on the board. Some questions we might ask of the lesson might be: Do females and males have the same chromosomes? If not what is different? What types of different physical characteristics did the dragons have? How many chromosomes did they have? Were there specific genes on each chromosome o ...
CAUSE - Cloudfront.net
CAUSE - Cloudfront.net

... with this disorder can’t stop bleeding when bleed to death from minor injured; can ________________ cuts or suffer internal bleeding from bruises or bumps. ...
Chapter 7 Clusters and Repeats
Chapter 7 Clusters and Repeats

... • pseudogenes – Inactive but stable components of the genome derived by mutation of an ancestral active gene. – Usually they are inactive because of mutations that block transcription or translation or both. ...
sex-linked recessive inheritance.
sex-linked recessive inheritance.

...  Homologous chromosomes interact, then segregate from one another during meiosis ...
Lecture 11-Chap07
Lecture 11-Chap07

... • pseudogenes – Inactive but stable components of the genome derived by mutation of an ancestral active gene. – Usually they are inactive because of mutations that block transcription or translation or both. ...
Introduction to Genetics using Punnett Squares
Introduction to Genetics using Punnett Squares

... • In humans, a cell’s nucleus contains 46 individual chromosomes or 23 pairs of chromosomes. • Half of the chromosomes come from one parent and half come from the other parent. Here is the detailed structure of a chromosome ...
Chapter 5 PRINCIPLES OF INHERITANCE AND VARIATION One
Chapter 5 PRINCIPLES OF INHERITANCE AND VARIATION One

... Morgan hybridized yellow bodied, white eyed females to brown-bodied, red eyed male and intercrossed their F1 progeny. He observed that the two genes did not segregate independently of each other and the F2 ratio deviated very significantly from 9:3:3:1. Morgan found that even when genes were grouped ...
Sex Chromosomes
Sex Chromosomes

... – what percentage of male offspring will express? – what percentage of female offspring will express if, • mate is hemizygous for the recessive allele? • mate is hemizygous for the dominant allele? ...
Word file (37 KB )
Word file (37 KB )

... took one sample out and used the remaining 77 samples to define a classifier based on the set of 231 discriminating genes. Then we predicted the outcome of the one sample we left out in the first place. The prediction of the left out sample is based on its correlation coefficient to the “good progno ...
Take-Home Exam 1
Take-Home Exam 1

... b. What chromosome is the CF gene located on? Describe two different approaches that could be used to map a gene to a particular chromosome. c. What is a genomic library? Why were genomic libraries essential to isolation of the CF gene? Describe how a lambda phage or cosmid genomic library, such as ...
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Epigenetics of human development

Development before birth, including gametogenesis, embryogenesis, and fetal development, is the process of body development from the gametes are formed to eventually combine into a zygote to when the fully developed organism exits the uterus. Epigenetic processes are vital to fetal development due to the need to differentiate from a single cell to a variety of cell types that are arranged in such a way to produce cohesive tissues, organs, and systems.Epigenetic modifications such as methylation of CpGs (a dinucleotide composed of a 2'-deoxycytosine and a 2' deoxyguanosine) and histone tail modifications allow activation or repression of certain genes within a cell, in order to create cell memory either in favor of using a gene or not using a gene. These modifications can either originate from the parental DNA, or can be added to the gene by various proteins and can contribute to differentiation. Processes that alter the epigenetic profile of a gene include production of activating or repressing protein complexes, usage of non-coding RNAs to guide proteins capable of modification, and the proliferation of a signal by having protein complexes attract either another protein complex or more DNA in order to modify other locations in the gene.
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