Biosynthesis of the Antibiotic Nonribosomal Peptide Penicillin in
... represent a particularly attractive class of enzymes for engineering efforts as they are inherently modular with each module region recognising one amino acid and incorporating it into the Nrp product15, 23. NRPS modules incorporate both the standard 20 amino acids, as well as hundreds of non-protei ...
... represent a particularly attractive class of enzymes for engineering efforts as they are inherently modular with each module region recognising one amino acid and incorporating it into the Nrp product15, 23. NRPS modules incorporate both the standard 20 amino acids, as well as hundreds of non-protei ...
RNA-guided gene drives can efficiently bias inheritance in wild yeast
... wild populations. As 'selfish' genetic elements, they spread not by improving the reproductive fitness of the organism, but by increasing the odds that they themselves will be inherited. Because this inheritance advantage can counteract the fitness costs associated with the drive itself or with adja ...
... wild populations. As 'selfish' genetic elements, they spread not by improving the reproductive fitness of the organism, but by increasing the odds that they themselves will be inherited. Because this inheritance advantage can counteract the fitness costs associated with the drive itself or with adja ...
The Nucleotide Sequence Determination of Catalases of Three
... amplified showed that those fragments contained sequences homologous with the known Candida catalases, indicating the usefulness of the designed primers. We determined the nucleotide sequences of the open reading frames and respective 5’ untranscribed regions of these yeasts and compared each sequen ...
... amplified showed that those fragments contained sequences homologous with the known Candida catalases, indicating the usefulness of the designed primers. We determined the nucleotide sequences of the open reading frames and respective 5’ untranscribed regions of these yeasts and compared each sequen ...
RNA-guided gene drives can efficiently bias inheritance in wild yeast
... wild populations. As 'selfish' genetic elements, they spread not by improving the reproductive fitness of the organism, but by increasing the odds that they themselves will be inherited. Because this inheritance advantage can counteract the fitness costs associated with the drive itself or with adja ...
... wild populations. As 'selfish' genetic elements, they spread not by improving the reproductive fitness of the organism, but by increasing the odds that they themselves will be inherited. Because this inheritance advantage can counteract the fitness costs associated with the drive itself or with adja ...
Reduced penetrance in human inherited disease
... (MYH7-mRNA) and mutated B-myosin transcript and proteins in familial hypertrophic cardiomyopathy. This is characteristic for each mutation, implying cis-acting regulatory mechanisms. [30]. Different degrees of expression in different individuals may also be due to variation in allelic constitution o ...
... (MYH7-mRNA) and mutated B-myosin transcript and proteins in familial hypertrophic cardiomyopathy. This is characteristic for each mutation, implying cis-acting regulatory mechanisms. [30]. Different degrees of expression in different individuals may also be due to variation in allelic constitution o ...
The dystrophin / utrophin homologues in Drosophila and in sea urchin
... products, we have searched for genes encoding dystrophin-like proteins in sea urchin and in Drosophila. We previously reported on the characterization of a sea urchin gene encoding a protein which is an evolutionary homologue of Dp116, one of the small products of the mammalian DMD gene, and on the ...
... products, we have searched for genes encoding dystrophin-like proteins in sea urchin and in Drosophila. We previously reported on the characterization of a sea urchin gene encoding a protein which is an evolutionary homologue of Dp116, one of the small products of the mammalian DMD gene, and on the ...
Genes - Mount Carmel Academy
... Assuming that you expect 5 heads and 5 tails in 10 tosses, how do the results of your tosses compare? How about the results of your partner’s tosses? How close was each set of results to what was expected? ...
... Assuming that you expect 5 heads and 5 tails in 10 tosses, how do the results of your tosses compare? How about the results of your partner’s tosses? How close was each set of results to what was expected? ...
Chapter 11: Complex Inheritance and Human Heredity
... Huntington’s disease The dominant genetic disorder Huntington’s disease affects the nervous system and occurs in one out of 10,000 people in the U.S. The symptoms of this disorder first appear in affected individuals between the ages of 30 and 50 years old. The symptoms include a gradual loss of bra ...
... Huntington’s disease The dominant genetic disorder Huntington’s disease affects the nervous system and occurs in one out of 10,000 people in the U.S. The symptoms of this disorder first appear in affected individuals between the ages of 30 and 50 years old. The symptoms include a gradual loss of bra ...
ZytoLight ® CLL I Probe SPEC TP53/ATM Dual Color Probe
... genes TP53 and ATM, and the ZytoLight ® CLL II Probe is designed for the detection of D13S319 deletions as well as for the enumeration of chromosome 12. CLL (chronic lymphocytic leukemia) is the most common form of leukemia in Western population. About 80% of the cases comprise genetic abnormalities ...
... genes TP53 and ATM, and the ZytoLight ® CLL II Probe is designed for the detection of D13S319 deletions as well as for the enumeration of chromosome 12. CLL (chronic lymphocytic leukemia) is the most common form of leukemia in Western population. About 80% of the cases comprise genetic abnormalities ...
December 2013 Newsletter - Wynnum Redlands Budgerigar Society
... Chromosomes come in pairs and have finite numbers in an organism. These chromosomes are partitioned into sites called loci (singular form: locus). The loci are very important, they are particular to characteristics. A gene not on the correct locus will simply not be expressed (in terms of the given ...
... Chromosomes come in pairs and have finite numbers in an organism. These chromosomes are partitioned into sites called loci (singular form: locus). The loci are very important, they are particular to characteristics. A gene not on the correct locus will simply not be expressed (in terms of the given ...
A method to detect single-nucleotide
... of –log(p-values) from the family-based association analysis is presented with a dashed line for comparison. From the ordered mean LodDiff values of SNPs, five causal SNPs (C4S4935, C6S2981, C10S3109, C4S1878, and C8S442) are included in the top 5% (Table 1). Among these five causal SNPs, the top th ...
... of –log(p-values) from the family-based association analysis is presented with a dashed line for comparison. From the ordered mean LodDiff values of SNPs, five causal SNPs (C4S4935, C6S2981, C10S3109, C4S1878, and C8S442) are included in the top 5% (Table 1). Among these five causal SNPs, the top th ...
misinformation, misrepresentation, and misuse of human behavioral
... more prone to violent behavior are also more likely to have certain genes, or if people who tend to score highly on standardized intelligence tests also share particular genetic traits. On the other hand, researchers interested in behaviors that do not vary significantly within a population have oth ...
... more prone to violent behavior are also more likely to have certain genes, or if people who tend to score highly on standardized intelligence tests also share particular genetic traits. On the other hand, researchers interested in behaviors that do not vary significantly within a population have oth ...
NCEA Level 1 Science (90948) 2014
... If a dominant allele was present, then individual 5 would be a tongue roller. So therefore they must have only both recessive alleles present. Individual 6 is a tongue roller, and so must have at least one dominant allele present for tongue rolling to be expressed. Both of 6’s children are a nontong ...
... If a dominant allele was present, then individual 5 would be a tongue roller. So therefore they must have only both recessive alleles present. Individual 6 is a tongue roller, and so must have at least one dominant allele present for tongue rolling to be expressed. Both of 6’s children are a nontong ...
Activation of Silent Genes by Transposons Tn5 and TnlO
... in reversion of his-203. Because of strain construction problems, the strains presented in lines 7 and 8 are independent transposition mutants; the insertions are in a common genetic background (his-203) but are not at the same chromosomal position. We have shown that chromosomal position of the par ...
... in reversion of his-203. Because of strain construction problems, the strains presented in lines 7 and 8 are independent transposition mutants; the insertions are in a common genetic background (his-203) but are not at the same chromosomal position. We have shown that chromosomal position of the par ...
Journal of Bacteriology
... copper binding sites. Thus, it is possible that the CusCFBA transenvelope transporter binds and transports periplasmic copper. Since the cus determinant is also responsible for a small increase in Ag(I) resistance (5), it is likely that the transported copper species is Cu(I). CopA from “R. metallid ...
... copper binding sites. Thus, it is possible that the CusCFBA transenvelope transporter binds and transports periplasmic copper. Since the cus determinant is also responsible for a small increase in Ag(I) resistance (5), it is likely that the transported copper species is Cu(I). CopA from “R. metallid ...
Liver Effects of Clinical Drugs Differentiated in Human Liver
... TBF (100 µM) initially increased or decreased liver ATP levels by 15% at 24 h, which stabilized to control levels at 48 h, then decreased significantly in one liver by 25% and increased significantly in another liver by 30% at 72 h. CBZ (100 µM) initially decreased ATP levels up to 23% in two livers ...
... TBF (100 µM) initially increased or decreased liver ATP levels by 15% at 24 h, which stabilized to control levels at 48 h, then decreased significantly in one liver by 25% and increased significantly in another liver by 30% at 72 h. CBZ (100 µM) initially decreased ATP levels up to 23% in two livers ...
Replication timing as an epigenetic mark
... consistent with increased intrinsic restrictions in cellular competence as cells become canalized farther down specific lineages.50 These restrictions are presumably due to changes in the epigenetic chromatin landscape that transcription factors must act upon during the reprogramming process. Howeve ...
... consistent with increased intrinsic restrictions in cellular competence as cells become canalized farther down specific lineages.50 These restrictions are presumably due to changes in the epigenetic chromatin landscape that transcription factors must act upon during the reprogramming process. Howeve ...
Price, DK, Zhang, F, Ashley, CT and Warren, ST: The chicken FMR1 gene is highly conserved containing a CTT 5\' untranslated repeat and encodes an RNA-binding protein. Genomics 31:3-12 (1996).
... brain FMR1 RNA. Indeed, while alternative splicing of exon 12 of the mammalian FMR1 gene has been documented in multiple tissues (Ashley et al., 1993a; Verkerk et al., 1993), alternative splicing events involving exon 11 have never been observed. Consistent with these observations, the absence of th ...
... brain FMR1 RNA. Indeed, while alternative splicing of exon 12 of the mammalian FMR1 gene has been documented in multiple tissues (Ashley et al., 1993a; Verkerk et al., 1993), alternative splicing events involving exon 11 have never been observed. Consistent with these observations, the absence of th ...
Natural Selection, Infectious Transfer and the Existence Conditions
... What happens when selective conditions fluctuate? For example, what happens when  is replaced by (t) ⱖ ⫺1, a sometimes-negative function of time? Though either chromosomals or plasmid-free cells will be favored at any given time, can plasmids persist over the long-term under fluctuating selection? ...
... What happens when selective conditions fluctuate? For example, what happens when  is replaced by (t) ⱖ ⫺1, a sometimes-negative function of time? Though either chromosomals or plasmid-free cells will be favored at any given time, can plasmids persist over the long-term under fluctuating selection? ...
Document
... chromosomes sorts maternal and paternal homologues into daughter cells independently of the other pairs ...
... chromosomes sorts maternal and paternal homologues into daughter cells independently of the other pairs ...
6.1 Chromosomes and Meiosis
... Your cells have autosomes and sex chromosomes. • Your body cells have 23 pairs of chromosomes. – Homologous pairs of chromosomes have the same structure. – For each homologous pair, one chromosome comes from each parent. • Chromosome pairs 1-22 are autosomes. • Sex chromosomes, X and Y, determine ge ...
... Your cells have autosomes and sex chromosomes. • Your body cells have 23 pairs of chromosomes. – Homologous pairs of chromosomes have the same structure. – For each homologous pair, one chromosome comes from each parent. • Chromosome pairs 1-22 are autosomes. • Sex chromosomes, X and Y, determine ge ...
Aucsia Gene Silencing Causes Parthenocarpic Fruit Development in
... Figure 1. Expression of SlAucsia-1 and SlAucsia-2 genes in tomato. A, cDNA-AFLP analysis showing down-regulation of SlAucsia-1 in preanthesis flower buds from two parthenocarpic auxin-synthesis (iaaM) tomato lines (DefH9-iaaM line 3 and DefH9-RI-iaaM line s5; Pandolfini et al., 2002). B, qRT-PCR ana ...
... Figure 1. Expression of SlAucsia-1 and SlAucsia-2 genes in tomato. A, cDNA-AFLP analysis showing down-regulation of SlAucsia-1 in preanthesis flower buds from two parthenocarpic auxin-synthesis (iaaM) tomato lines (DefH9-iaaM line 3 and DefH9-RI-iaaM line s5; Pandolfini et al., 2002). B, qRT-PCR ana ...
CAIcal: A combined set of tools to assess codon usage adaptation
... The most important contribution that we aim to provide with our server is to tie together several features, previously existing but disseminated throughout the Internet, and some new features related to CAI calculation and analysis, and to implement them into a single and easy-touse web site. Descri ...
... The most important contribution that we aim to provide with our server is to tie together several features, previously existing but disseminated throughout the Internet, and some new features related to CAI calculation and analysis, and to implement them into a single and easy-touse web site. Descri ...