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Full Text  - Archives of Pediatric Infectious Diseases
Full Text - Archives of Pediatric Infectious Diseases

... to combat the spread of NDM-1. This is going to be a challenge and will require international cooperation (9). ...
the loci of evolution: how predictable is genetic
the loci of evolution: how predictable is genetic

... which alter the amino-acid sequence or the mature RNA nucleotide sequence; (2) cis-regulatory changes, which alter gene expression; and (3) genetic changes that alter both the coding and the cis-regulatory regions of one or several gene(s) (gene loss, gene duplication, gene rearrangement, etc.). Cod ...
Low chromosome number angiosperms
Low chromosome number angiosperms

... stable diploid karyotype and one cell line with 2n=5 only. Adachi et al. (1997) reported chromosomal location of 45S and 5S rDNA in all the species of B. lineariloba complex. In B. dichromosomatica each of the 5S and 45S rDNA loci occurred at two sites on chromosomes even if chromosome 2 has been su ...
Study of seven single-nucleotide polymorphisms identified in East
Study of seven single-nucleotide polymorphisms identified in East

... serious public health issue in Taiwan. Obesity is regarded as a complex multifactorial disease in which genes play a very important role. Genetic variations may predispose individuals to obesity by controlling the balance between energy intake and expenditure.3 4 ...
The Interplay of Temperature and Genotype on Patterns
The Interplay of Temperature and Genotype on Patterns

... stages (Jin et al. 2001; Wang et al. 2008; Graveley et al. 2011; Zhou et al. 2012; Smith et al. 2013; Brown et al. 2014; Etges et al. 2015). Much less is known about the influence of environmental conditions on this plasticity (Levine et al. 2011; Yampolsky et al. 2012; Telonis-Scott et al. 2013; Bro ...
Supplemental Tables
Supplemental Tables

... (http://rana.lbl.gov/drosophila/). The orthology calls made by V. Iyer and M. Eisen, which were also posted at the AAA site, were also used in this analysis. The FlyBase inferred cytological map locations were assigned to all of the orthologs called in the four species. These associations were then ...
Down syndrome: characterisation of a case with partial trisomy of
Down syndrome: characterisation of a case with partial trisomy of

... aberrations, it is difficult to evaluate the contribution of the chromosome 21 duplication to these. In fact, deletion of 1 5q26-qter, as in our patient, has been associated with both preand postnatal growth retardation, clinodactyly, microcephaly, developmental and speech delay, cafe au lait spots, ...
Mutational analysis of protein phosphatase 2C involved in abscisic
Mutational analysis of protein phosphatase 2C involved in abscisic

... protoplast transient assay. The role of PP2Cs as negative regulators in ABA signaling is supported by the identification of mutations that abolish PP2C activity and its inhibitory effect on ABA-inducible transcription. Interestingly, two types of dominant interfering mutants with greatly diminished ...
Category 2000
Category 2000

... Peroxisome proliferator-activated receptor coactivator 1 (PPARGC1A) is a versatile coactivator with many functions, but is primarily involved in fat and energy metabolism. Therefore, it is a very interesting candidate gene for meat quality, which is one of the most important criteria in pig selectio ...
Day and Night
Day and Night

... Scientists noticed that other genes in these mutated flies were less active after sleep deprivation. These genes, which produce "heat shock" proteins, were artificially stimulated prior to sleep deprivation by raising the fly's environment to human body temperature. "These 'heat shock' proteins prot ...
Phenotypic data in FlyBase
Phenotypic data in FlyBase

... allele records for D. melanogaster genes, of which 39,293 were `traditional' and 9,141 were of the `in vitro construct' type. One powerful application of genetically engineered alleles is in determining the amount of genomic DNA within and around the transcription unit that is required for full func ...
Row
Row

... Use the following information to answer the next three questions The Romanovs, the Russian royal family, were shot dead during the Russian Revolution in 1918. The family included Czar Nicholas II and his wife Alexandra; their daughters, Olga, Maria, Tatiana, and Anastasia; and their son Alexis, who ...
File - Groby Bio Page
File - Groby Bio Page

... The production of pigment in rabbit fur is controlled by two genes. One gene controls whether any pigment is made. This gene has three alleles. Allele A codes for the production of one form of the enzyme tyrosinase, which converts tyrosine into a black pigment. Allele Ah codes for the production of ...
Integrated genome sequence and linkage map of physic nut
Integrated genome sequence and linkage map of physic nut

... and 0.746 Mbp, respectively, which are approximately 1.8 and 46.8 times longer, respectively, than the reported physic nut genome (Hirakawa et al., 2012). As the result of short contigs and scaffolds, too many predicted genes in their study were fragmented. Only 17 Mbp (6%) of their assembly (but ab ...
The cell-cycle interactome: a source of growth
The cell-cycle interactome: a source of growth

... cell-division phase during which mitosis (M) takes place, separated by two gap phases (G1 and G2). Progression through these different phases needs to be tightly controlled at the molecular level in order to allow correct transmission of the genetic information (De Veylder et al., 2003; Harashima et ...
Ribosome Profiling
Ribosome Profiling

... expression by analyzing entire transcripts can provide important insights into the spatial and temporal gene regulation inside a cell. Microarray and RNA sequencing (RNA-seq) are two extensively used techniques to analyze genome wide abundances of transcripts. It is pertinent to note that regulation ...
2006 - Genetics, development and evolution of adaptive
2006 - Genetics, development and evolution of adaptive

... ‘hood’ was selected to be small in some lines and large in others. Castle initially thought these size differences reflected different alleles of the major gene responsible for hooding; however, Wright showed that so-called modifier genes were responsible for variation in hood size, providing the fi ...
Evidence for Mitotic Crossing-over During the
Evidence for Mitotic Crossing-over During the

... It has been established that chromosome I1 carries the four genes: tsgD acrA whi axe2. However, when the diploids resulting from the crosses x9 x ~8 or x9 x ~ 2 were 4 plated on methanol-containing media, methanol resistant diploids as well as the methanol resistant haploids discussed previously wer ...
Creating conditional dual fluorescence labelled transgenic animals
Creating conditional dual fluorescence labelled transgenic animals

... In addition to messenger RNA that encodes proteins, non-coding RNAs, including microRNA (miRNA) and long non-coding RNA (lncRNA) have been shown to be involved in gene regulation at post-transcriptional and translational levels. For example, microRNAs, about 22 nucleotide long, are among the largest ...
Lecture 10: Reproduction II: Sexual Reproduction and Meiosis
Lecture 10: Reproduction II: Sexual Reproduction and Meiosis

... • Reshuffling of alleles during sexual reproduction produces genetic variation in gametes • It brings together alleles that were not together before ...
Germline Selection: Population Genetic Aspects of the
Germline Selection: Population Genetic Aspects of the

... arguments as to theirevolution and maintenance remain unresolved. Sexual reproduction occurs when individuals inherit genes from two parents resulting in theproduction of new combinationsof alleles. Individuals fortunateenoughtoinherit favorable combinations will flourish, leave numerous offspring, ...
Phytoalexin-Deficient Mutants of Arabidopsis Reveal That
Phytoalexin-Deficient Mutants of Arabidopsis Reveal That

... LANT resistance to microbial pathogens is often mediated by “gene-for-gene’’ interactions, in which specific pathogen genes, called avirulence genes, result in specific recognition by plants carrying corresponding resistance ( R ) genes (FLOR 1971).Gene-forgene recognition oftenleads to expression o ...
Prader-Willi and Angelman syndromes: Sister imprinted disorders
Prader-Willi and Angelman syndromes: Sister imprinted disorders

... to chromosome 15q11-q13. They both have characteristic neurologic, developmental, and behavioral phenotypes plus other structural and functional abnormalities. However, the cognitive and neurologic impairment is more severe in AS, including seizures and ataxia. The behavioral and endocrine disorders ...
A New Player in the Spermiogenesis Pathway of
A New Player in the Spermiogenesis Pathway of

... A suppressor screen of spe-27(it132ts) designed to identify additional members of the SPE-8 pathway turned up numerous mutations that suppress spe-27 mutant sterility (Muhlrad and Ward 2002). Interestingly, none of the spe-27 suppressors characterized so far are members of the SPE-8 group activation ...
Hybrid Sterility and Hybrid Breakdown
Hybrid Sterility and Hybrid Breakdown

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Epigenetics of human development

Development before birth, including gametogenesis, embryogenesis, and fetal development, is the process of body development from the gametes are formed to eventually combine into a zygote to when the fully developed organism exits the uterus. Epigenetic processes are vital to fetal development due to the need to differentiate from a single cell to a variety of cell types that are arranged in such a way to produce cohesive tissues, organs, and systems.Epigenetic modifications such as methylation of CpGs (a dinucleotide composed of a 2'-deoxycytosine and a 2' deoxyguanosine) and histone tail modifications allow activation or repression of certain genes within a cell, in order to create cell memory either in favor of using a gene or not using a gene. These modifications can either originate from the parental DNA, or can be added to the gene by various proteins and can contribute to differentiation. Processes that alter the epigenetic profile of a gene include production of activating or repressing protein complexes, usage of non-coding RNAs to guide proteins capable of modification, and the proliferation of a signal by having protein complexes attract either another protein complex or more DNA in order to modify other locations in the gene.
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