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Genetics
Genetics

... 1. EST-SSR discovery and validation in cowpea and genetic diversity 2. EST-SNP discovery and validation in cowpea and genetic diversity 3. SNP discovery from genotyping by sequencing in cowpea 4. Genetic diversity analysis for world-wide cowpea germplasm 5. Association analysis of low phosphorus eff ...
Molecular pathogenesis of liver adenomas and FNH - HAL
Molecular pathogenesis of liver adenomas and FNH - HAL

... these tumors. Novel markers specific to these subtypes have been developed, implicating a potential for use in clinical practice. In this review, we will focus on the recent progress in understanding of the molecular mechanisms in these two hepatocellular tumors. 1 - Focal Nodular Hyperplasia (FNH) ...
Cartesian Genetic Programming
Cartesian Genetic Programming

... Fig. 2.5 Picture produced when the program encoded in the evolved genotype shown in Fig. 2.4 is executed. It arose in the sixth generation. The user decides which genotype will be the next parent. ...
Single-copy nuclear genes resolve the phylogeny of the
Single-copy nuclear genes resolve the phylogeny of the

... often placed as sister to Mecopterida and the latter traditionally included either within, or as sister to, Coleoptera [9,10]. The consensus view is that most morphological features of Hymenoptera and Strepsiptera are too highly modified to unequivocally resolve their phylogenetic positions [11,12]. ...
Genetics
Genetics

... GENETICS ...
Bacterial plasmids - Micro-Rao
Bacterial plasmids - Micro-Rao

... Conjugation is a specialized from of the Type IV secretion system. Conjugation involves two dissimilar functions; the first one has to do with a site on plasmid called oriT or mob, which refers to origin of transfer and the second one involves functions of proteins (coded by tra genes) that are nec ...
WEREWOLF, a Regulator of Root Hair Pattern
WEREWOLF, a Regulator of Root Hair Pattern

... addition, the heterozygous lines obtained from the cross between Col and wer-1 showed similar flowering time with Col, confirming that wer is a recessive lateflowering mutant (Supplemental Fig. S1). The flowering time in Arabidopsis is regulated by four major pathways: photoperiod, vernalization, au ...
9th Grade Reading Problems of the Day
9th Grade Reading Problems of the Day

... these findings provide a road map for plant breeders to make better-tasting, evenly red tomatoes. The discovery “is one piece of the puzzle about why the modern tomato stinks,” said Harry Klee, a tomato researcher at the University of Florida in Gainesville who was not involved in the research. “Tha ...
Abdominal Aortic Aneurysms(AAA)
Abdominal Aortic Aneurysms(AAA)

... which results in an amino acid change (i.e. missense mutation) and destabilizes the mutant TGFBR2 protein structure of the aortic media, was segregated in a family with BAV and proximal aortic aneurysm . ...
Ph1
Ph1

... Incorrect pairing leads to unbalanced gametes and infertility How does wheat produce 4 haploid cells at the end of meiosis? ...
ACTIN-RELATED PROTEIN6 Regulates Female Meiosis By
ACTIN-RELATED PROTEIN6 Regulates Female Meiosis By

... of yeast. In the yeast SWR1 complex, ARP6 facilitates binding between other subunits, such as Swc2, and the ATPase domain of SWR1. In Arabidopsis, ARP6 acts in the nucleus (Deal et al., 2005; Meagher et al., 2005) to modulate gene expression in vegetative development and repression of flowering (Marc ...
Chromosomes in Saccharomyces cerevisiae
Chromosomes in Saccharomyces cerevisiae

... the products of the mating could grow. Because cells which have lost the marked chromosome III derivative can divide a small number of times on leucine-free medium, the results are expressed as the frequency of chromosome loss (chromosome loss events per cell) rather than the rate of chromosome loss ...
Supporting Information Parfenov et al. 10.1073/pnas.1416074111
Supporting Information Parfenov et al. 10.1073/pnas.1416074111

... P values (adjusted by the Benjamini–Hochberg procedure) less than 0.05 were considered as significantly differentially methylated or expressed. The sites and corresponding statistics for all CpG loci and genes can be found in Dataset S1, Tables S3 and S4. Additionally, we carried out an unsupervised ...
Methods for detecting positive selection and examples among fungi
Methods for detecting positive selection and examples among fungi

... detect particular sites subject to an increased nonsynonymous rate. The Bayesian method can be employed to infer which sites in the alignment are under positive selection. This method is used to compute the posterior probability that each site belongs to a particular v class. A site with a posterior ...
Linköping University Post Print Neuronal Subtype Specification within a Feed-Forward Loops
Linköping University Post Print Neuronal Subtype Specification within a Feed-Forward Loops

Delivering copper within plant cells Edward Himelblau* and
Delivering copper within plant cells Edward Himelblau* and

... toxic. For example, free copper will readily oxidize the thiol bonds within proteins causing a disruption of their secondary structure. Thus, cells must accumulate copper and distribute it to the cellular components that require it while preventing its toxic effects. Work in yeast, mice and humans, ...
HapTree-X: An integrative Bayesian framework for haplotype
HapTree-X: An integrative Bayesian framework for haplotype

... which contains only the exons in a gene separated by introns. Positions marked in red denote heterozygous-SNP loci. Paired-end sequencing reads are of length 2x4bp and have 3-4 bp insert lengths; reference alleles overlapping SNP loci are marked with red and alternative alleles are marked with blue. ...
LINKAGE AND MAPPING IN EUKARYOTES
LINKAGE AND MAPPING IN EUKARYOTES

... fter Sutton suggested the chromosomal theory of inheritance in 1903, evidence accumulated that genes were located on chromosomes. For example, Morgan showed by an analysis of inheritance patterns that the white-eye locus in Drosophila is located on the X chromosome. Given that any organism has many ...
Evolutionary dynamics of nematode operons
Evolutionary dynamics of nematode operons

... abundant in nematode genomes. The “one-way street” hypothesis asserts that once formed by chance, operons are very difficult to break, because the breakage would leave downstream genes in an operon without a promoter, and hence, unexpressed. To test this hypothesis, we analyzed the presence and abse ...
Hypoxia-inducible factor 1 is a new target of microphthalmia
Hypoxia-inducible factor 1 is a new target of microphthalmia

... of the melanocyte-specific form of microphthalmia-associated transcription factor (MITF) (Bertolotto et al., 1998a), a basic helix-loop-helix transcription factor that plays a key role not only in melanin synthesis, but also in melanocyte development and survival (Hodgkinson et al., 1993; Hughes et ...
Genetic Etiologies for Phenotypic Diversity in Sickle Cell Anemia
Genetic Etiologies for Phenotypic Diversity in Sickle Cell Anemia

... N12(TA)10 structure, HbF (0.9%) and F cells (8.3%) were about twice as high as found with other configurations for this region[25]. These data suggest that HbF is influenced by elements 3' to HS-2 and 5' to the HBG2 promoter. F-cell numbers in Benin haplotype sickle cell trait carriers were more str ...
1 - DORAS
1 - DORAS

... The ferrioxamines are low molecular weight, water soluble, trihydroxamate type siderophores. They were first isolated and characterised from a Streptomyces species in 1960 (Baumler and Hantke, 1992). There are many different types of ferrioxamines, classified based on their chemical structure. Strep ...
genetics - Liceocopernico.it
genetics - Liceocopernico.it

... cell pigment called hemoglobin. Some anemic individuals have an altered form of this gene, i.e., an allele, which makes a defective hemoglobin protein unable to carry the normal amount of oxygen to the body cells. Each gene occupies a specific position on a chromosome, called the gene locus (loci, p ...
My PP Genetics
My PP Genetics

... Most of the bases in the genome consist of “junk DNA” with no known function. The chromosomes differ in the number of genes they carry. ...
Conjugative plasmids: vessels of the communal gene pool
Conjugative plasmids: vessels of the communal gene pool

... many cases as ‘selfish’ operons (Lawrence 2003). These two factors, compactness and gene clustering, mean that many conferrable traits can be transferred between discrete replicating elements (chromosomes or plasmids) by the movement of relatively small fragments of DNA. Phylogenetic analyses of com ...
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Epigenetics of human development

Development before birth, including gametogenesis, embryogenesis, and fetal development, is the process of body development from the gametes are formed to eventually combine into a zygote to when the fully developed organism exits the uterus. Epigenetic processes are vital to fetal development due to the need to differentiate from a single cell to a variety of cell types that are arranged in such a way to produce cohesive tissues, organs, and systems.Epigenetic modifications such as methylation of CpGs (a dinucleotide composed of a 2'-deoxycytosine and a 2' deoxyguanosine) and histone tail modifications allow activation or repression of certain genes within a cell, in order to create cell memory either in favor of using a gene or not using a gene. These modifications can either originate from the parental DNA, or can be added to the gene by various proteins and can contribute to differentiation. Processes that alter the epigenetic profile of a gene include production of activating or repressing protein complexes, usage of non-coding RNAs to guide proteins capable of modification, and the proliferation of a signal by having protein complexes attract either another protein complex or more DNA in order to modify other locations in the gene.
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