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... 45. Some diseases, such as cystic fibrosis, can be inherited even if neither parent has the disease. What is the most likely cause of this? (A) dominant alleles (B) environment (C) recessive alleles (D) weakened immune system 49. Skin color in humans is an example of what type of inheritance? (A) in ...
Deciphering the role of DNA methylation in multiple sclerosis
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The Chromosomes of a Frimpanzee
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Gene prediction and Genome Annotation

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The Differential Killing of Genes by Inversions in Prokaryotic Genomes

... lying on the leading strand is stronger. But if we assume that selection is responsible for the more conserved character of the genes on the leading strand, we should ask: why are these genes located preferentially on the leading strand? It seems reasonable to answer that it is because the mutation ...
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Epigenetics of human development

Development before birth, including gametogenesis, embryogenesis, and fetal development, is the process of body development from the gametes are formed to eventually combine into a zygote to when the fully developed organism exits the uterus. Epigenetic processes are vital to fetal development due to the need to differentiate from a single cell to a variety of cell types that are arranged in such a way to produce cohesive tissues, organs, and systems.Epigenetic modifications such as methylation of CpGs (a dinucleotide composed of a 2'-deoxycytosine and a 2' deoxyguanosine) and histone tail modifications allow activation or repression of certain genes within a cell, in order to create cell memory either in favor of using a gene or not using a gene. These modifications can either originate from the parental DNA, or can be added to the gene by various proteins and can contribute to differentiation. Processes that alter the epigenetic profile of a gene include production of activating or repressing protein complexes, usage of non-coding RNAs to guide proteins capable of modification, and the proliferation of a signal by having protein complexes attract either another protein complex or more DNA in order to modify other locations in the gene.
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