Technical Targets
... Probing Hydrogenase Maturation Machinery in CBS The overarching goal is to construct a cyanobacterial recombinant harboring the O2-tolerant hydrogenase from Rubrivivax gelatinosus CBS using Synechocystis sp. PCC 6803 as a model host for sustained photolytic H2 production. A prerequisite for success ...
... Probing Hydrogenase Maturation Machinery in CBS The overarching goal is to construct a cyanobacterial recombinant harboring the O2-tolerant hydrogenase from Rubrivivax gelatinosus CBS using Synechocystis sp. PCC 6803 as a model host for sustained photolytic H2 production. A prerequisite for success ...
Evolution of synonymous codon usage in metazoans Laurent Duret
... codon bias and gene expression is due to a transcriptioncoupled mutational process [8•] and thus shows directly that synonymous codon usage is shaped by natural selection in these two invertebrates. Few experimental data on the cellular abundances of tRNA in metazoans are available. But it is possib ...
... codon bias and gene expression is due to a transcriptioncoupled mutational process [8•] and thus shows directly that synonymous codon usage is shaped by natural selection in these two invertebrates. Few experimental data on the cellular abundances of tRNA in metazoans are available. But it is possib ...
Transgenic Tobacco Plants with Bacillus thuringiensis 8
... which leads to osmotic imbalance and cell lysis (Hofmann et ai., 1988; Slatin et ai., 1990; English et al., 1991; English and Slatin, 1992). Among insecticidal protein genes, lepidopteran specific genes, cryJA class, are mostly well characterized (Adang et al., 1985; Thorne et al., 1986; Schnepf et ...
... which leads to osmotic imbalance and cell lysis (Hofmann et ai., 1988; Slatin et ai., 1990; English et al., 1991; English and Slatin, 1992). Among insecticidal protein genes, lepidopteran specific genes, cryJA class, are mostly well characterized (Adang et al., 1985; Thorne et al., 1986; Schnepf et ...
SGD: Saccharomyces Genome Database.
... Sequence Similarity View and Stripe View. Pattern Matching, Sequence Similarity View and Stripe View are all programs created by SGD staff. Pattern Matching allows users to perform a variety of motif searches, using degenerate search sequences. Sequence Similarity View and Stripe View provide a visu ...
... Sequence Similarity View and Stripe View. Pattern Matching, Sequence Similarity View and Stripe View are all programs created by SGD staff. Pattern Matching allows users to perform a variety of motif searches, using degenerate search sequences. Sequence Similarity View and Stripe View provide a visu ...
Gene Flow - nslc.wustl.edu
... fst and Molecule Genetic Distance • When you survey for genetic variation at the DNA sequence level, there is often so much variation that the probability of two randomly chosen genes being identical, even within the same deme, is very small and therefore hard to estimate reliably. “Heterozygosit ...
... fst and Molecule Genetic Distance • When you survey for genetic variation at the DNA sequence level, there is often so much variation that the probability of two randomly chosen genes being identical, even within the same deme, is very small and therefore hard to estimate reliably. “Heterozygosit ...
YEAST GENETICS AND MOLECULAR BIOLOGY
... In order to do yeast genetics and to grow haploid cells in the laboratory, mating type switch must be prevented: all laboratory strains are HO mutants and can not switch So how does this mysterious switch of sex work? ...
... In order to do yeast genetics and to grow haploid cells in the laboratory, mating type switch must be prevented: all laboratory strains are HO mutants and can not switch So how does this mysterious switch of sex work? ...
Phylogeny, taxonomy, and evolution of the endothelin receptor gene
... along the basal internode that interconnects the two most recent common ancestors of the two groups. The most obvious example of a type II position is one that is fixed for radically different amino acids between therians and non-therians. In contrast, a conserved position is one with a constant site ...
... along the basal internode that interconnects the two most recent common ancestors of the two groups. The most obvious example of a type II position is one that is fixed for radically different amino acids between therians and non-therians. In contrast, a conserved position is one with a constant site ...
CDKN2 (p16/MTS1) Gene Deletion or CDK4
... CDKN2, MTS2, and surrounding loci in a series of 70 human glioma tissue samples. The findings support a role for the CDKN2 gene as a tumor suppressor gene in glioblastomas and anaplastic astrocytomas; furthermore we have found that CDK4 gene amplification is a com mon abnormality in tumors not showi ...
... CDKN2, MTS2, and surrounding loci in a series of 70 human glioma tissue samples. The findings support a role for the CDKN2 gene as a tumor suppressor gene in glioblastomas and anaplastic astrocytomas; furthermore we have found that CDK4 gene amplification is a com mon abnormality in tumors not showi ...
application of next generation sequencing in the diagnosis
... found 9. The most common form of AS, with approximately 4 in every 5 cases, is inherited in an X-linked fashion. X linked carrier females usually show variable intermediate phenotype. Due to imbalances in random X inactivation the phenotype can vary even between family members. In case of FBH, the m ...
... found 9. The most common form of AS, with approximately 4 in every 5 cases, is inherited in an X-linked fashion. X linked carrier females usually show variable intermediate phenotype. Due to imbalances in random X inactivation the phenotype can vary even between family members. In case of FBH, the m ...
ABSTRACT Using a bioinformatics approach to identify genes that
... categorizations. While public users can enter a gene set into GeneWeaver, most gene sets are derived directly from experimentation (GWAS, Microarray, etc.) or publications. For example, PubMed, a database for scientific literature, can be used to find articles that describe gene sets, and these gene ...
... categorizations. While public users can enter a gene set into GeneWeaver, most gene sets are derived directly from experimentation (GWAS, Microarray, etc.) or publications. For example, PubMed, a database for scientific literature, can be used to find articles that describe gene sets, and these gene ...
Gene Duplication, Gene Conversion and the Evolution of
... Nonrecombining chromosomes, such as the Y, are expected to degenerate over time due to reduced efficacy of natural selection compared to chromosomes that recombine. However, gene duplication, coupled with gene conversion between duplicate pairs, can potentially counteract forces of evolutionary deca ...
... Nonrecombining chromosomes, such as the Y, are expected to degenerate over time due to reduced efficacy of natural selection compared to chromosomes that recombine. However, gene duplication, coupled with gene conversion between duplicate pairs, can potentially counteract forces of evolutionary deca ...
Warren, ST and Nelson, DL: Trinucleotide repeat expansions in neurological disease. Current Opinion in Neurobiology 3:752-759 (1993).
... are born to affected mothers rather than to affected fathers may be explained by this paternal size reduction, as congenital DM is always associated with very large CTG-repeat expansions [49*]. O’Hoy et al. [ 50**] showed that some apparent reductions in repeat length are due to gene conversion even ...
... are born to affected mothers rather than to affected fathers may be explained by this paternal size reduction, as congenital DM is always associated with very large CTG-repeat expansions [49*]. O’Hoy et al. [ 50**] showed that some apparent reductions in repeat length are due to gene conversion even ...
Evidence for Mito-Nuclear and Sex-Linked Reproductive Barriers
... can be difficult to study in hybrid species due to lack of geographical contact between taxa. However, the Italian sparrow lives parapatrically with the house sparrow and both sympatrically and parapatrically with the Spanish sparrow. Through whole-transcriptome sequencing of six individuals of each ...
... can be difficult to study in hybrid species due to lack of geographical contact between taxa. However, the Italian sparrow lives parapatrically with the house sparrow and both sympatrically and parapatrically with the Spanish sparrow. Through whole-transcriptome sequencing of six individuals of each ...
- Haematopoietic Stem Cell Lab
... CD41 and VE-cadherin expression were analysed by flow cytometry between E7.0 and E8.25 of mouse embryonic development. Seven distinct developmental stages between E7.0 and E8.5 were analysed. A distinct CD41 bright population only becomes clearly separable by FACS at the ES stage. LS = late streak s ...
... CD41 and VE-cadherin expression were analysed by flow cytometry between E7.0 and E8.25 of mouse embryonic development. Seven distinct developmental stages between E7.0 and E8.5 were analysed. A distinct CD41 bright population only becomes clearly separable by FACS at the ES stage. LS = late streak s ...
reviews - Department of Genetics
... radiation-induced mutations. In laboratory animals, modifier effects are usually attributed to genetic background and can be inherited as Mendelian or polygenic traits. In most cases, the genetic basis for modification is unknown; in some cases, modifier genes have been mapped; in several cases, can ...
... radiation-induced mutations. In laboratory animals, modifier effects are usually attributed to genetic background and can be inherited as Mendelian or polygenic traits. In most cases, the genetic basis for modification is unknown; in some cases, modifier genes have been mapped; in several cases, can ...
Supplementary Information
... DNA and RNA fractions were isolated from the tissue using an AllPrep DNA/RNA mini kit (Qiagen) per the manufacturer’s procedure. Approximately 120 mg of frozen GBM tissue was lysed in a buffer containing guanidine-isothiocyanate to inactivate DNases and RNases and to ensure isolation of intact DNA a ...
... DNA and RNA fractions were isolated from the tissue using an AllPrep DNA/RNA mini kit (Qiagen) per the manufacturer’s procedure. Approximately 120 mg of frozen GBM tissue was lysed in a buffer containing guanidine-isothiocyanate to inactivate DNases and RNases and to ensure isolation of intact DNA a ...
17q12 microdeletions - Unique The Rare Chromosome Disorder
... see how well the kidneys are working. If just one kidney is affected, the other kidney (without cysts) can usually compensate. If both kidneys have cysts, replacement treatment may be needed, either by dialysis or renal transplant. Other kidney and urinary tract anomalies have also been found in peo ...
... see how well the kidneys are working. If just one kidney is affected, the other kidney (without cysts) can usually compensate. If both kidneys have cysts, replacement treatment may be needed, either by dialysis or renal transplant. Other kidney and urinary tract anomalies have also been found in peo ...
Y chromosome azoospermia factor region microdeletions and
... Int J Clin Exp Med 2015;8(9):14634-14646 ...
... Int J Clin Exp Med 2015;8(9):14634-14646 ...
The hybrid origins of three perennial Medicago species
... animal kingdom. Species formed by hybridization often have different phenotype and better fitness than either the parents (Otto 2007). However, in other cases, depending on the relatedness of the parents, the descendants may also be sterile. This is caused by chromosomal ...
... animal kingdom. Species formed by hybridization often have different phenotype and better fitness than either the parents (Otto 2007). However, in other cases, depending on the relatedness of the parents, the descendants may also be sterile. This is caused by chromosomal ...
Assembly of additional heterochromatin distinct from centromere
... artificial chromosomes (HAC) with functional centromeres that depend on type I alphoid arrays composed of highly homogenous higher-order repeating units (Harrington et al., 1997; Ikeno et al., 1998; Masumoto et al., 1998; Henning et al., 1999; Ebersole et al., 2000; Mejia et al., 2001; Grimes et al. ...
... artificial chromosomes (HAC) with functional centromeres that depend on type I alphoid arrays composed of highly homogenous higher-order repeating units (Harrington et al., 1997; Ikeno et al., 1998; Masumoto et al., 1998; Henning et al., 1999; Ebersole et al., 2000; Mejia et al., 2001; Grimes et al. ...
A Conserved Molecular Framework for Compound Leaf Development
... Figure S4. Detailed analysis of NAM genes expression in serial sections of S. lycopersicum (A,C), S. tuberosum (B) and P. sativum (D). A. SlNAM expression in an older S. lycopersicum leaf. Note that SlNAM is not expressed in the centre of the region between leaflet primordia 1 and 2 (ltp1, ltp2) but ...
... Figure S4. Detailed analysis of NAM genes expression in serial sections of S. lycopersicum (A,C), S. tuberosum (B) and P. sativum (D). A. SlNAM expression in an older S. lycopersicum leaf. Note that SlNAM is not expressed in the centre of the region between leaflet primordia 1 and 2 (ltp1, ltp2) but ...
Meiotic DSBs and the control of mammalian recombination
... ~15 000 hotspots, with very little overlap between them. This is the strongest indication yet that nearly all hotspots are PRDM9-dependent. Each allele-specific set of hotspots was characterized by a distinct DNA motif at the center of the hotspots, the extent of whose match to the PRDM9 consensus s ...
... ~15 000 hotspots, with very little overlap between them. This is the strongest indication yet that nearly all hotspots are PRDM9-dependent. Each allele-specific set of hotspots was characterized by a distinct DNA motif at the center of the hotspots, the extent of whose match to the PRDM9 consensus s ...
pSAT vectors: a modular series of plasmids for autofluorescent
... 35S terminator and producing pSAT6-nosPnosT-EGFP-C1. A DNA fragment containing three copies of the Gal4 UAS and the TATA box from the 35S promoter were cloned by triple ligation of AgeI-EcoRI and MfeI-NcoI PCR fragments, respectively, from pTA7001 (AoyamaandChua, 1997) into the AgeI-NcoI sites of pS ...
... 35S terminator and producing pSAT6-nosPnosT-EGFP-C1. A DNA fragment containing three copies of the Gal4 UAS and the TATA box from the 35S promoter were cloned by triple ligation of AgeI-EcoRI and MfeI-NcoI PCR fragments, respectively, from pTA7001 (AoyamaandChua, 1997) into the AgeI-NcoI sites of pS ...
