Solid Tumour Section Angiomatoid fibrous histiocytoma (AFH) Atlas of Genetics and Cytogenetics
... Clinically, the tumor is often mistaken for hematoma or hemangioma. The diagnosis of angiomatoid fibrous histiocytoma is made on the basis of histopathology and immunohistochemical studies. Three microscopic findings are characteristic of AFH: (1) solid arrays or nests of histiocyte-like cells, (2) ...
... Clinically, the tumor is often mistaken for hematoma or hemangioma. The diagnosis of angiomatoid fibrous histiocytoma is made on the basis of histopathology and immunohistochemical studies. Three microscopic findings are characteristic of AFH: (1) solid arrays or nests of histiocyte-like cells, (2) ...
The quantitative genetics of sexual dimorphism
... 1987; Arnold, 1985; Bonduriansky and Rowe, 2005), but this latter expectation is somewhat more tenuous because rAmf depends on the additive genetic variances in each sex in addition to the covariance and may not change in parallel with COVAmf (Reeve and Fairbairn, 2001). These predictions are derive ...
... 1987; Arnold, 1985; Bonduriansky and Rowe, 2005), but this latter expectation is somewhat more tenuous because rAmf depends on the additive genetic variances in each sex in addition to the covariance and may not change in parallel with COVAmf (Reeve and Fairbairn, 2001). These predictions are derive ...
chapter 3 transmission genetics – chromosomes, recombination and
... Statistical Tests for Mendelian Inheritance What if Mendel had observed only a small number of F2’s instead of several hundred or even thousands of offspring? Would he have observed the 3:1 and 9:3:3:1 ratios that led him to formulate the laws of inheritance? Genetic segregation is a random process ...
... Statistical Tests for Mendelian Inheritance What if Mendel had observed only a small number of F2’s instead of several hundred or even thousands of offspring? Would he have observed the 3:1 and 9:3:3:1 ratios that led him to formulate the laws of inheritance? Genetic segregation is a random process ...
HOMOLOGY IN BIOLOGY: A Problem for Naturalistic Science
... or the post-Darwinian phylogenetic definition. If similar genes can "determine" such radically different structures, then those genes aren't really determining structure at all. Instead, they appear to be functioning as binary switches between alternate developmental fates, with the information for ...
... or the post-Darwinian phylogenetic definition. If similar genes can "determine" such radically different structures, then those genes aren't really determining structure at all. Instead, they appear to be functioning as binary switches between alternate developmental fates, with the information for ...
Improved Efficacy of a Gene Optimised Adenovirus
... The genes encoding the structural proteins, E3-E2-6K, were optimised using GeneOptimizer™ (Geneart GmbH, Regensburg). This included codon usage adaptation, optimal for mammalian expression. One measure of codon quality is the Codon Adaptation Index (CAI), a measurement for the relative adaptiveness ...
... The genes encoding the structural proteins, E3-E2-6K, were optimised using GeneOptimizer™ (Geneart GmbH, Regensburg). This included codon usage adaptation, optimal for mammalian expression. One measure of codon quality is the Codon Adaptation Index (CAI), a measurement for the relative adaptiveness ...
2002-11-14: Quantitative Traits IV
... be added to explain the observed phenotype? If not, there are significant nonlinear interactions exist. Is the inheritance and distribution of genes at one contributing locus independent of another contributing locus? How might this not be true? Does gene expression vary with environmental conte ...
... be added to explain the observed phenotype? If not, there are significant nonlinear interactions exist. Is the inheritance and distribution of genes at one contributing locus independent of another contributing locus? How might this not be true? Does gene expression vary with environmental conte ...
Mechanisms of Evolution
... random chance. It occurs if a population is not infinite in size. In populations that are not infinitely large, there will be random error in which alleles are passed from generation, and allele frequencies will change at random. Since no population is really infinitely large, there is always some g ...
... random chance. It occurs if a population is not infinite in size. In populations that are not infinitely large, there will be random error in which alleles are passed from generation, and allele frequencies will change at random. Since no population is really infinitely large, there is always some g ...
Role of microRNA in Skeleton Development
... complex that contains the RNaseIII-containing protein Drosha, with cofactors such as DGCR8 and p68. The microprocessor is a prerequisite for the biosynthesis of most miRNAs [3, 8, 25, 67J.After microprocessing, the pre-miRNA hairpin is exported from the nucleus by Exportin-5 [47, 86J and is subject ...
... complex that contains the RNaseIII-containing protein Drosha, with cofactors such as DGCR8 and p68. The microprocessor is a prerequisite for the biosynthesis of most miRNAs [3, 8, 25, 67J.After microprocessing, the pre-miRNA hairpin is exported from the nucleus by Exportin-5 [47, 86J and is subject ...
Genetics
... Who is Gregor Mendel? e. Purebred refers to an organism with a pair of the same genes for a given trait (either dominant or recessive). This is known as being homozygous. f. Hybrid refers to an organism with two different genes for a trait (one dominant and one recessive). This is known as being he ...
... Who is Gregor Mendel? e. Purebred refers to an organism with a pair of the same genes for a given trait (either dominant or recessive). This is known as being homozygous. f. Hybrid refers to an organism with two different genes for a trait (one dominant and one recessive). This is known as being he ...
Meiosis forms variable gametes
... genes at the same loci. Each homologous chromosome is inherited from a different parent; therefore the alleles of the genes of homologous chromosomes may be different. • Crossing over occurs at chiasmata during meiosis I. This process shuffles sections of DNA between the homologous pairs allowing th ...
... genes at the same loci. Each homologous chromosome is inherited from a different parent; therefore the alleles of the genes of homologous chromosomes may be different. • Crossing over occurs at chiasmata during meiosis I. This process shuffles sections of DNA between the homologous pairs allowing th ...
The Evolution of Populations
... • The average is about one mutation in every 100,000 genes per generation • Mutations rates are often lower in prokaryotes and higher in viruses ...
... • The average is about one mutation in every 100,000 genes per generation • Mutations rates are often lower in prokaryotes and higher in viruses ...
Eukaryote-to-eukaryote gene transfer events revealed by the
... for the EC1118 genes flanking the region B are shown in light blue. Arrows represent ORFs and their orientation. Genes are identified by their name, and the chromosome or the scaffold to which they belong is shown by a letter or a number within the arrow. In EC1118, N refers to the scaffold N26, and ...
... for the EC1118 genes flanking the region B are shown in light blue. Arrows represent ORFs and their orientation. Genes are identified by their name, and the chromosome or the scaffold to which they belong is shown by a letter or a number within the arrow. In EC1118, N refers to the scaffold N26, and ...
The Role of the COP/DET/FUS Genes in Light
... Within the context of this genetic model, it is not surprising that all severe mutations also lead to a fusca phenotype, since anthocyanin accumulation is one of the lightinducible traits that increases quantitatively with higher light intensity. Therefore, a complete loss of function of these repre ...
... Within the context of this genetic model, it is not surprising that all severe mutations also lead to a fusca phenotype, since anthocyanin accumulation is one of the lightinducible traits that increases quantitatively with higher light intensity. Therefore, a complete loss of function of these repre ...
Status of the p53, p16, RB1, and HER
... characteristics. We found chromosomal numerical aberrations in all specimens analysed. Nevertheless, when malignant and non-malignant cells were compared, significant differences were seen only for chromosomes 7 and 17. These results, in agreement with those of Cordon-Cardo et al,8 show that the T3– ...
... characteristics. We found chromosomal numerical aberrations in all specimens analysed. Nevertheless, when malignant and non-malignant cells were compared, significant differences were seen only for chromosomes 7 and 17. These results, in agreement with those of Cordon-Cardo et al,8 show that the T3– ...
Memphis/Le Bonheur CF Family Day - The Cystic Fibrosis Center at
... Are there other mutations that we can use VX-770 (ivacaftor/Kalydeco) to treat? • Ivacaftor is being investigated for other mutations, keep in contact with you CF center about trials • Other drugs, and combinations are being studied as well – Ataluren – VX-770/809 ...
... Are there other mutations that we can use VX-770 (ivacaftor/Kalydeco) to treat? • Ivacaftor is being investigated for other mutations, keep in contact with you CF center about trials • Other drugs, and combinations are being studied as well – Ataluren – VX-770/809 ...
The global repressor FliZ antagonizes gene
... expression mediated by pS by recognizing operator sequences that resemble the 10 region of pSdependent promoters. FliZ does so with a structural element that is similar to region 3.0 of pS. Within this element, R108 in FliZ corresponds to K173 in pS, which contacts a conserved cytosine at the 13 p ...
... expression mediated by pS by recognizing operator sequences that resemble the 10 region of pSdependent promoters. FliZ does so with a structural element that is similar to region 3.0 of pS. Within this element, R108 in FliZ corresponds to K173 in pS, which contacts a conserved cytosine at the 13 p ...
Epigenetic inheritance of expression states in plant development
... in Drosophila contrasts with the widespread expression of PcG proteins [4]. Similar observations were made in plants, as we pointed out for the overlapping expression patterns of the PcG proteins CLF and VRN2 and their target genes AG and FLC, respectively. This implies that highly selective mechani ...
... in Drosophila contrasts with the widespread expression of PcG proteins [4]. Similar observations were made in plants, as we pointed out for the overlapping expression patterns of the PcG proteins CLF and VRN2 and their target genes AG and FLC, respectively. This implies that highly selective mechani ...
Nucleotide Polymorphisms in the 2 Gene Define
... Fig 1. Structure of the a2 gene surrounding the 807 and 873 polymorphisms. Three a2 gene alleles, defined by eight nucleotide polymorphisms, are indicated in the figure. Exons 6 through 9 are shown in boxes; positions of the exons in the cDNA sequence and the length of each exon are indicated beneat ...
... Fig 1. Structure of the a2 gene surrounding the 807 and 873 polymorphisms. Three a2 gene alleles, defined by eight nucleotide polymorphisms, are indicated in the figure. Exons 6 through 9 are shown in boxes; positions of the exons in the cDNA sequence and the length of each exon are indicated beneat ...
Full Text - The International Journal of Developmental Biology
... neural tube, and later in the intermediate zone of the spinal cord, myelencephalon and metencephalon (Names at af., 1990; Asano and Gruss. 1992). Pax2 is also expressed in developing kidneys (Dressler af al., 1990), defined regions of otic vesicle and in the optic cup and stalk (Names et al., 1990). ...
... neural tube, and later in the intermediate zone of the spinal cord, myelencephalon and metencephalon (Names at af., 1990; Asano and Gruss. 1992). Pax2 is also expressed in developing kidneys (Dressler af al., 1990), defined regions of otic vesicle and in the optic cup and stalk (Names et al., 1990). ...
A systemic gene silencing method suitable for high throughput
... [17-20], indicating that they share a common and evolutionarily conserved mechanism that is likely to be present in all plants, including ferns. One striking feature of gene silencing is that the silencing effects are non-cell autonomous and spread to neighboring cells. For this reason, transient ex ...
... [17-20], indicating that they share a common and evolutionarily conserved mechanism that is likely to be present in all plants, including ferns. One striking feature of gene silencing is that the silencing effects are non-cell autonomous and spread to neighboring cells. For this reason, transient ex ...
Module one assignment
... the speed and ease with which you pick up new things will increase. This course is built to be like that - one which you can do at your own pace, in your own time, and progressing only when you are ready. The first four modules of this course introduce you to a wide range of genetic concepts and tec ...
... the speed and ease with which you pick up new things will increase. This course is built to be like that - one which you can do at your own pace, in your own time, and progressing only when you are ready. The first four modules of this course introduce you to a wide range of genetic concepts and tec ...
PDF
... Isolation and characterization of XRnf12 To determine whether Rnf12 plays any role in regulating the activity of Xlim-1, we isolated the Xenopus Rnf12 ortholog by degenerate PCR procedure and subsequent screening of a Xenopus gastrula cDNA library. We obtained a clone encoding a protein of 616 amino ...
... Isolation and characterization of XRnf12 To determine whether Rnf12 plays any role in regulating the activity of Xlim-1, we isolated the Xenopus Rnf12 ortholog by degenerate PCR procedure and subsequent screening of a Xenopus gastrula cDNA library. We obtained a clone encoding a protein of 616 amino ...
cluster analysis I
... : training data : testing data : K-means clustering cetroids from training data : comembership matrix ...
... : training data : testing data : K-means clustering cetroids from training data : comembership matrix ...
controversy and its implications Genetic hitchhiking versus
... alleles in recombining regions (Fay & Wu 2000). In particular, this second property has later become important in identifying hitchhiking events in chromosomal regions of normal recombination rates (Kim & Stephan 2002; see below). While a hitchhiking effect may be caused by the fixation of a single ...
... alleles in recombining regions (Fay & Wu 2000). In particular, this second property has later become important in identifying hitchhiking events in chromosomal regions of normal recombination rates (Kim & Stephan 2002; see below). While a hitchhiking effect may be caused by the fixation of a single ...