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Imam - TU Delft
Imam - TU Delft

... • Many approaches generate TRNs based on the assumption: expression is directly related to cognate transcription factors (TFs). • Drawback: Compromised by indirect effects such as co-expressed ...
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Genetics
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UNIT 4: DNA and Genetics
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Concept Check Questions with answers
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NMPDRposter - Edwards @ SDSU
NMPDRposter - Edwards @ SDSU

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Genetics Slides - The Adapa Project

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Child Psychology, Second Canadian Edition
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... – The bases form pairs such as adenosinethymine or guaninecytosine – The DNA strand is in the form of a double helix made up of a series of base pairs ...
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Genomic imprinting

Genomic imprinting is the epigenetic phenomenon by which certain genes are expressed in a parent-of-origin-specific manner. If the allele inherited from the father is imprinted, it is thereby silenced, and only the allele from the mother is expressed. If the allele from the mother is imprinted, then only the allele from the father is expressed. Forms of genomic imprinting have been demonstrated in fungi, plants and animals. Genomic imprinting is a fairly rare phenomenon in mammals; most genes are not imprinted.In insects, imprinting affects entire chromosomes. In some insects the entire paternal genome is silenced in male offspring, and thus is involved in sex determination. The imprinting produces effects similar to the mechanisms in other insects that eliminate paternally inherited chromosomes in male offspring, including arrhenotoky.Genomic imprinting is an inheritance process independent of the classical Mendelian inheritance. It is an epigenetic process that involves DNA methylation and histone methylation without altering the genetic sequence. These epigenetic marks are established (""imprinted"") in the germline (sperm or egg cells) of the parents and are maintained through mitotic cell divisions in the somatic cells of an organism.Appropriate imprinting of certain genes is important for normal development. Human diseases involving genomic imprinting include Angelman syndrome and Prader–Willi syndrome.
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