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Lecture 10 and lecture 11(70 slides) - Dr-Manar-KSU
Lecture 10 and lecture 11(70 slides) - Dr-Manar-KSU

... It is common ‫ شائع‬in meiosis and includes: a) Chromosomal deletions/translocations  Homologous chromatids may break ‫ تـَنكسر‬and rejoin at incorrect places, thus, one chromatid will loose more genes than it receives. ...
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BL 414 Genetics Spring 2006 Study Guide for Test 3
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... A) Inactivation of X and Y linked genes occurs during meiosis in male germ cells. 1) This is the result of pairing and condensation of the sex chromosomes into a “sex vesicle.” 2) Following meiosis, some X and Y linked genes are once again expressed. B) X chromosome reactivation in oocytes. 1) For o ...
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Genomic imprinting

Genomic imprinting is the epigenetic phenomenon by which certain genes are expressed in a parent-of-origin-specific manner. If the allele inherited from the father is imprinted, it is thereby silenced, and only the allele from the mother is expressed. If the allele from the mother is imprinted, then only the allele from the father is expressed. Forms of genomic imprinting have been demonstrated in fungi, plants and animals. Genomic imprinting is a fairly rare phenomenon in mammals; most genes are not imprinted.In insects, imprinting affects entire chromosomes. In some insects the entire paternal genome is silenced in male offspring, and thus is involved in sex determination. The imprinting produces effects similar to the mechanisms in other insects that eliminate paternally inherited chromosomes in male offspring, including arrhenotoky.Genomic imprinting is an inheritance process independent of the classical Mendelian inheritance. It is an epigenetic process that involves DNA methylation and histone methylation without altering the genetic sequence. These epigenetic marks are established (""imprinted"") in the germline (sperm or egg cells) of the parents and are maintained through mitotic cell divisions in the somatic cells of an organism.Appropriate imprinting of certain genes is important for normal development. Human diseases involving genomic imprinting include Angelman syndrome and Prader–Willi syndrome.
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