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Function and Control of the Spx-Family of Proteins Within
Function and Control of the Spx-Family of Proteins Within

... the Firmicutes. In B. subtilis, the gene, yjbD (now known as spx), encoding an ArsC-like protein, was observed to be activated by several stress-inducing conditions, including phosphate starvation and elevated temperature (Antelmann et al. 2000; Petersohn et al. 2001). The spx gene resides within a ...
The landscape of Neandertal ancestry in present
The landscape of Neandertal ancestry in present

... ρSpearman=0.176, P = 0.02 for East Asians) (Fig. 2, SI 8). Studies in many species have shown that genes responsible for reduced male fertility disproportionally map to chromosome X20–22. We hypothesized that this “Large X Effect” 23 could explain why chromosome X was more resistant to introgression ...
Genetic Analysis of Variation in Human Meiotic Recombination
Genetic Analysis of Variation in Human Meiotic Recombination

... genome-wide association study to identify genetic variants that influence the number of meiotic recombination events per gamete. We found three loci that influence female recombination and three different loci that influence male recombination. Our results suggest that gender differences in recombin ...
Expression and function of decapentaplegic and thick veins during
Expression and function of decapentaplegic and thick veins during

... carried out using the same protocols, but the hybridisation step and washes were at 55°C. The following DNA probes were used: 2 kb EcoRI fragment from a dpp cDNA clone (St. Johnston et al., 1990), 1.4 kb EcoRI/ClaI from a tkv cDNA clone (Nellen et al., 1994), 3 kb EcoRI from a Dl cDNA clone (Vassin ...
Virulence factors of Salmonella enterica serovar Enteritidis
Virulence factors of Salmonella enterica serovar Enteritidis

... humans, the infection can manifest as a non-bloody diarrhea with abdominal pain, nausea, vomiting and fever. The disease (non-typhoidal fever) is usually self-limiting and recovery follows within a few days to a week but, occasionally, systemic infection may occur in vulnerable human patients such a ...
"RNA Interference in Caenorhabditis elegans".
"RNA Interference in Caenorhabditis elegans".

... just over 550 cells. Newly hatched larvae progress through four larval molts to reach adulthood in 3 days, and adult hermaphrodites produce 300 self-progeny over the next 3 days. Both larval and adult worms have remarkably simple anatomies, consisting of an inner tube comprising the pharynx and in ...
Tapanes-Castillo A, Weaver EJ, Smith RP, Kamei Y, Caspary T, Hamilton-Nelson KL, Slifer SH, Martin ER, Bixby JL, Lemmon VP. Neurogenetics. 2012 Feb;11(1):53-71. A modifier locus on chromosome 5 contributes to L1 cell adhesion molecule X-linked hydrocephalus in mice.
Tapanes-Castillo A, Weaver EJ, Smith RP, Kamei Y, Caspary T, Hamilton-Nelson KL, Slifer SH, Martin ER, Bixby JL, Lemmon VP. Neurogenetics. 2012 Feb;11(1):53-71. A modifier locus on chromosome 5 contributes to L1 cell adhesion molecule X-linked hydrocephalus in mice.

... on the reason for the defect in CSF flow. Communicating hydrocephalus arises from problems with CSF secretion or resorption; CSF flows freely between the ventricles and the subarachnoid space. On the other hand, noncommunicating hydrocephalus develops when a physical obstruction blocks CSF flow betw ...
Coffee B, Ikeda M, Budimirovic DB, Hjelm LN, Kaufmann WE and Warren ST: Mosaic FMR1 Deletion Causes Fragile X Syndrome and Can Lead to Molecular Misdiagnosis: A Case Report and Review of the Literature. American J of Medical Genetics Part A 146A:1358-1367 (2008).
Coffee B, Ikeda M, Budimirovic DB, Hjelm LN, Kaufmann WE and Warren ST: Mosaic FMR1 Deletion Causes Fragile X Syndrome and Can Lead to Molecular Misdiagnosis: A Case Report and Review of the Literature. American J of Medical Genetics Part A 146A:1358-1367 (2008).

... However, other mutational mechanisms, such as deletions of FMR1, also cause fragile X syndrome. The result is the same for both the expansion mediated silencing and deletion, absence of the gene product, FMRP. We report here on an 11-year-old boy with a cognitive and behavioral profile with features ...
Applying Mendel`s Principles
Applying Mendel`s Principles

... A Summary of Mendel’s Principles Before long, Morgan and other biologists had tested every one of Mendel’s principles and learned that they applied not just to pea plants but to other organisms as well. The basic principles of Mendelian genetics can be used to study the inheritance of human traits a ...
3 Citrate metabolism and aroma compound production in lactic acid
3 Citrate metabolism and aroma compound production in lactic acid

... the end products. Therefore, the interest of the dairy industry in controlling citrate utilization by LAB has promoted research into the proteins and effectors controlling its metabolic pathway. In this chapter we summarize the current knowledge of citrate utilization by LAB. The transport of citrat ...
Bacillus subtilis antibiotics: structures, syntheses and specific functions
Bacillus subtilis antibiotics: structures, syntheses and specific functions

... 2002). The BdbB paralogue BdbC protein is at least partially able to replace BdbB in sublancin production, but contrariwise BdbB cannot complement the function of BdbC (competence development), showing that these two closely related thiol-disulphide oxidoreductases have different, but partly overlap ...
Cellular Biology
Cellular Biology

... If two alleles are found together, the allele that is observable is dominant, and the one whose effects are hidden is recessive In genetics, the dominant allele is represented by a capital letter, and the recessive by a lowercase letter Alleles can be co-dominant ...
Standard PDF - Wiley Online Library
Standard PDF - Wiley Online Library

... each probe hybridized to a single band in all electrophoretic karyotypes tested, indicating that if P. carinii are diploid, their homologous chromosomes do not exhibit length polymorphism. The possibility that chromosome length polymorphism does not occur in P. carinii seems unlikely because the DNA ...
::: Gene Set Enrichment Analysis - GSEA
::: Gene Set Enrichment Analysis - GSEA

... The heat map shows the (clustered) genes in the leading edge subsets. In a heat map, expression values are represented as colors, where the range of colors (red, pink, light blue, dark blue) shows the range of expression values (high, moderate, low, lowest). ...
children-and-their-development-second-canadian
children-and-their-development-second-canadian

... A) are more often caused by recessive alleles than by dominant alleles. B) are more often caused by dominant alleles than by recessive alleles. C) are due to dominant alleles about half the time. D) do not usually seriously impair a child’s development. Answer: A Page Reference: 50 Topic: Mechanisms ...
Genetic Determinants Differences between Vibrio cholerae Biotypes
Genetic Determinants Differences between Vibrio cholerae Biotypes

... transporter (rtxBD) genes (36). RTX gene cluster in El Tor V. cholerae encodes a cytotoxic activity for HEp-2 cells in vitro. The toxin, RtxA, resembles members of the RTX toxin family as it contains a GD-rich repeated motif. Like other RTX toxins, its activity depends on an activator, RtxC, and an ...
Visceral endoderm-restricted translation of Otx1
Visceral endoderm-restricted translation of Otx1

... dorsal telencephalon where Otx2 is not transcribed. Therefore, these findings support two hypotheses: (i) Otx1 and Otx2 functional properties might largely overlap and differences in their temporal and spatial transcriptional control might account for the highly divergent phenotypes observed in mice ...
Improvement of Aspergillus nidulans penicillin production by
Improvement of Aspergillus nidulans penicillin production by

... description of the inhibition of bacteria through Penicillium notatum cultures to the first human trials or even general application of the antibiotic, many years of research passed. One of the major problems at the time was the yield of penicillin. Even nowadays increasing the yield of penicillin pr ...
Children and Their Development, Second Canadian Edition Kail
Children and Their Development, Second Canadian Edition Kail

... A) are more often caused by recessive alleles than by dominant alleles. B) are more often caused by dominant alleles than by recessive alleles. C) are due to dominant alleles about half the time. D) do not usually seriously impair a child’s development. Answer: A Page Reference: 50 Topic: Mechanisms ...
FREE Sample Here
FREE Sample Here

... A) are more often caused by recessive alleles than by dominant alleles. B) are more often caused by dominant alleles than by recessive alleles. C) are due to dominant alleles about half the time. D) do not usually seriously impair a child’s development. Answer: A Page Reference: 50 Topic: Mechanisms ...
Here - Orrery Software
Here - Orrery Software

... Survival of the Fittest -------------------------------------------------------------------------------------------------31 PSoup and Control of Life Functions ------------------------------------------------------------------------------35 PSoup and Plant-Like Phenotypes --------------------------- ...
GSEA - Bioinformatics Unit
GSEA - Bioinformatics Unit

... The heat map shows the (clustered) genes in the leading edge subsets. In a heat map, expression values are represented as c where the range of colors (red, pink, light blue, dark blue) shows the range of expression values (high, moderate, low, lowest). ...
wmgenes2 - Cucurbit Breeding
wmgenes2 - Cucurbit Breeding

... they have dgdg genotype (Rhodes, 1986). The juvenile albino ja (Zhang et al., 1996b) gene causes reduced chlorophyll in seedling tissues, as well as leaf margins and fruit rind when plants are grown under short day conditions. The dominant gene Sp (Poole, 1944) causes round yellow spots to form on c ...
High grade B-cell lymphomas (HGBL): Altered terminology in the
High grade B-cell lymphomas (HGBL): Altered terminology in the

... HR: Enriched for markers of T-cell-mediated immune response and classical complement pathway; increased expression of an overlapping set of inflammatory mediators and connective tissue components The three consensus clusters have similar 5-yr-survivals, suggesting the clusters may be more useful for ...
Publication - The University of Texas Health Science Center at
Publication - The University of Texas Health Science Center at

... supports a strong genetic link to scleroderma. Also reviewed are the family and twin studies that suggest a genetic component in scleroderma, and recent genetic-association studies implicating specific genes in the pathogenetic triad of autoimmunity, endothelial dysfunction, and fibroblast activation. ...
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Genomic imprinting

Genomic imprinting is the epigenetic phenomenon by which certain genes are expressed in a parent-of-origin-specific manner. If the allele inherited from the father is imprinted, it is thereby silenced, and only the allele from the mother is expressed. If the allele from the mother is imprinted, then only the allele from the father is expressed. Forms of genomic imprinting have been demonstrated in fungi, plants and animals. Genomic imprinting is a fairly rare phenomenon in mammals; most genes are not imprinted.In insects, imprinting affects entire chromosomes. In some insects the entire paternal genome is silenced in male offspring, and thus is involved in sex determination. The imprinting produces effects similar to the mechanisms in other insects that eliminate paternally inherited chromosomes in male offspring, including arrhenotoky.Genomic imprinting is an inheritance process independent of the classical Mendelian inheritance. It is an epigenetic process that involves DNA methylation and histone methylation without altering the genetic sequence. These epigenetic marks are established (""imprinted"") in the germline (sperm or egg cells) of the parents and are maintained through mitotic cell divisions in the somatic cells of an organism.Appropriate imprinting of certain genes is important for normal development. Human diseases involving genomic imprinting include Angelman syndrome and Prader–Willi syndrome.
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