Cloning and expression of the phosphotriesterase
... fusion when cultures were grown in the absence of phosphate, suggesting that it might be part of the Pho regulon, but the phosphate-regulated promoter was not cloned in this study. This is believed to be the first study in which a gene required for an organism to grow with OP pesticides as a phospho ...
... fusion when cultures were grown in the absence of phosphate, suggesting that it might be part of the Pho regulon, but the phosphate-regulated promoter was not cloned in this study. This is believed to be the first study in which a gene required for an organism to grow with OP pesticides as a phospho ...
Genomic Analysis of Hox Clusters in the Sea Lamprey
... genes to Hox cognate groups, the complete homeodomain amino acid sequences from P. marinus were aligned with those from mouse and amphioxus. This alignment was then used in a neighbor-joining analysis resulting in the bootstrapped tree of Figure 3. The known mouse Hox gene cognates cluster together ...
... genes to Hox cognate groups, the complete homeodomain amino acid sequences from P. marinus were aligned with those from mouse and amphioxus. This alignment was then used in a neighbor-joining analysis resulting in the bootstrapped tree of Figure 3. The known mouse Hox gene cognates cluster together ...
Genetic Polymorphisms Underlying Lung Cancer - J
... Three chromosomal loci, 15q24-25.1, 5p15.33 and 6p21, were found to be associated with lung cancer risk in GWASs of European/American populations (2–4), while locus 3q28 was associated with lung ADC risk in a GWAS of Japanese/Korean populations (7). The chromosomal 15q24-25.1 region contains nicotin ...
... Three chromosomal loci, 15q24-25.1, 5p15.33 and 6p21, were found to be associated with lung cancer risk in GWASs of European/American populations (2–4), while locus 3q28 was associated with lung ADC risk in a GWAS of Japanese/Korean populations (7). The chromosomal 15q24-25.1 region contains nicotin ...
Development of an internally controlled real-time PCR
... primers targeting the ompA gene were developed. The IC DNA contained the same primer-binding sites and had the same length and nucleotide content as the C. psittaci DNA amplicon, but had a shuffled probe-binding region. The lower limit of detection was 80 target copies ⁄ PCR, corresponding to 6250 c ...
... primers targeting the ompA gene were developed. The IC DNA contained the same primer-binding sites and had the same length and nucleotide content as the C. psittaci DNA amplicon, but had a shuffled probe-binding region. The lower limit of detection was 80 target copies ⁄ PCR, corresponding to 6250 c ...
Musil et al - Merit Research Journals
... genetic analysis of two human renal agenesis causing candidate genes encoding the RET receptor thyrosin kinase and GDNF neutrophic factor. The mutational analysis of twenty RET exons and three GDNF exons in twenty patients diagnosed with unilateral renal agenesis was carried out. Furthermore, copy n ...
... genetic analysis of two human renal agenesis causing candidate genes encoding the RET receptor thyrosin kinase and GDNF neutrophic factor. The mutational analysis of twenty RET exons and three GDNF exons in twenty patients diagnosed with unilateral renal agenesis was carried out. Furthermore, copy n ...
MS26/CYP704B is required for anther and pollen wall
... homozygous TaMs26 mutation. Utilizing the above mentioned five deletions in A-, B- and Dgenomes, three sets of triple mutants were generated i) A-4 bp Δ, B-23 bp Δ, D-90 bp Δ; ii) A-4 bp Δ, B-81 bp Δ, D-90 bp Δ; iii) A-4 bp Δ, B-23 bp Δ, D-96 bp Δ + 2 bp I. Plants heterozygous for triple mutations ( ...
... homozygous TaMs26 mutation. Utilizing the above mentioned five deletions in A-, B- and Dgenomes, three sets of triple mutants were generated i) A-4 bp Δ, B-23 bp Δ, D-90 bp Δ; ii) A-4 bp Δ, B-81 bp Δ, D-90 bp Δ; iii) A-4 bp Δ, B-23 bp Δ, D-96 bp Δ + 2 bp I. Plants heterozygous for triple mutations ( ...
VUMC team pinpoints genes that dictate five fingers
... its precise role was not clear,” Chiang said. “We show that it’s not important for skeletal formation; where it’s really important is in determining digit number and identity.” Sonic hedgehog and Gli3 work together to pattern the pentadactyl — five-fingered — limb. Gli3 is a protein that turns other ...
... its precise role was not clear,” Chiang said. “We show that it’s not important for skeletal formation; where it’s really important is in determining digit number and identity.” Sonic hedgehog and Gli3 work together to pattern the pentadactyl — five-fingered — limb. Gli3 is a protein that turns other ...
Population genetics and the modern synthesis of evolutionary theory
... − and eventually, a small number of cells in that part of the body “inherit” the mutation − when the organism dies, the mutation is eliminated, too − if the mutation causes the cell to grow and divide wildly - as in a cancer - then the abnormal growth of tissue may be harmful to the organism, even k ...
... − and eventually, a small number of cells in that part of the body “inherit” the mutation − when the organism dies, the mutation is eliminated, too − if the mutation causes the cell to grow and divide wildly - as in a cancer - then the abnormal growth of tissue may be harmful to the organism, even k ...
ABO Blood Group System
... present in the sera of people who have had no exposure to human red cells ...
... present in the sera of people who have had no exposure to human red cells ...
Foundations of Biology
... bulge appears in images of polytene chromosomes In situ hybridization using cosmid clones mapped to that region show hybridization on the outside of this structure, but not in the middle Figure from http://www.helsinki.fi/~saura/EM/xdiv2.html ...
... bulge appears in images of polytene chromosomes In situ hybridization using cosmid clones mapped to that region show hybridization on the outside of this structure, but not in the middle Figure from http://www.helsinki.fi/~saura/EM/xdiv2.html ...
Genetic mapping of aphicarus – a sex-linked locus
... mechanisms controlling the production of such alternative phenotypes. Most importantly, we do not know which genes play a direct role in causing divergence of alternative developmental pathways. In general, it is difficult to identify such critical genes in a polyphenic ...
... mechanisms controlling the production of such alternative phenotypes. Most importantly, we do not know which genes play a direct role in causing divergence of alternative developmental pathways. In general, it is difficult to identify such critical genes in a polyphenic ...
The zebrafish as a model for muscular dystrophy and congenital
... Thus, despite sharing the phenotype of muscle degeneration at the whole organism level at the cellular level, the pathology of sap mutant zebrafish is apparently different to that of human muscular dystrophies, where membrane damage occurs along the length of the fibre. The DAPC is localized embryon ...
... Thus, despite sharing the phenotype of muscle degeneration at the whole organism level at the cellular level, the pathology of sap mutant zebrafish is apparently different to that of human muscular dystrophies, where membrane damage occurs along the length of the fibre. The DAPC is localized embryon ...
Книжечка
... Resolution is defined as the minimum distance that two points can be separated and still be distinguished as two separate points. One way to increase resolution is to increase magnification – to make small objects seem larger. Robert Hooke and Antonie van Leeuwenhoek were able to see very small cel ...
... Resolution is defined as the minimum distance that two points can be separated and still be distinguished as two separate points. One way to increase resolution is to increase magnification – to make small objects seem larger. Robert Hooke and Antonie van Leeuwenhoek were able to see very small cel ...
Genetic, psychosocial, and demographic factors associated with
... indicators of behavioral disinhibition: nicotine, alcohol consumption, alcohol dependence, illicit drugs, and nonsubstance-related behavioral disinhibition. This study found only one SNP (rs1868152) that attained genomewide significance (P = 5 9 10 8), for the indicator of illicit drug use, but auth ...
... indicators of behavioral disinhibition: nicotine, alcohol consumption, alcohol dependence, illicit drugs, and nonsubstance-related behavioral disinhibition. This study found only one SNP (rs1868152) that attained genomewide significance (P = 5 9 10 8), for the indicator of illicit drug use, but auth ...
Fragile X Syndrome
... types of alleles are defined with different clinical manifestations3,13: Normal alleles, up to 44 CGG repeats; premutation (PM) alleles, between 55 and 200 and full mutation alleles (FM) with more than 200 repeats. The fourth type of allele is named “grey zone” or intermediate allele and contains be ...
... types of alleles are defined with different clinical manifestations3,13: Normal alleles, up to 44 CGG repeats; premutation (PM) alleles, between 55 and 200 and full mutation alleles (FM) with more than 200 repeats. The fourth type of allele is named “grey zone” or intermediate allele and contains be ...
Biochemical, or Molecular, Genetics
... of an organism • Phenotype is the organism’s evident biological characteristics – Natural selection only act on phenotypes – Environmental influence in this interaction extremely important – Lends great plasticity to human biology ...
... of an organism • Phenotype is the organism’s evident biological characteristics – Natural selection only act on phenotypes – Environmental influence in this interaction extremely important – Lends great plasticity to human biology ...
A dynamic deterministic model to optimize a multiple
... is an optimization technique based on an evolution of a population of artificial individuals. Each individual is a point in the research space and is characterized by its “chromosome” Ck, which determines the individual fitness h(Ck); k = 1,..., n; n is a population size. The evolution process consi ...
... is an optimization technique based on an evolution of a population of artificial individuals. Each individual is a point in the research space and is characterized by its “chromosome” Ck, which determines the individual fitness h(Ck); k = 1,..., n; n is a population size. The evolution process consi ...
Apolipoprotein E Testing for Alzheimer Disease
... Despite clarification of issues related to clinical validation,[20] information concerning the predictive value of the epsilon-4 allele for AD from some laboratories currently marketing the APOE test is being misinterpreted. It is important to distinguish between APOE and other AD susceptibility loc ...
... Despite clarification of issues related to clinical validation,[20] information concerning the predictive value of the epsilon-4 allele for AD from some laboratories currently marketing the APOE test is being misinterpreted. It is important to distinguish between APOE and other AD susceptibility loc ...
Polyploidy Enhances F Pollen Sterility Loci
... rates, limits their commercial utility. To decipher the cytological and molecular mechanisms underlying allelic interactions in autotetraploid rice, we developed an autotetraploid rice hybrid that was heterozygous (SiSj) at F1 pollen sterility loci (Sa, Sb, and Sc) using near-isogenic lines. Cytolog ...
... rates, limits their commercial utility. To decipher the cytological and molecular mechanisms underlying allelic interactions in autotetraploid rice, we developed an autotetraploid rice hybrid that was heterozygous (SiSj) at F1 pollen sterility loci (Sa, Sb, and Sc) using near-isogenic lines. Cytolog ...
rational selection of pcr-based platforms for pharmacogenomic testing
... development of neoplastic diseases and individual variations in responses to specific drugs. Costand time-effective technologies able to accurately identify genetic polymorphisms will dramatically affect routine diagnostics processes and future therapeutic developments. However, such methods need to ...
... development of neoplastic diseases and individual variations in responses to specific drugs. Costand time-effective technologies able to accurately identify genetic polymorphisms will dramatically affect routine diagnostics processes and future therapeutic developments. However, such methods need to ...
Case Report Section
... Nine previously reported cases have been identified on literature review (see references below) with a broad age of onset (7-68 years, median 39), many with monocytic differentiation, frequently aberrant immunophenotypic antigen expression (often with CD7 and/or CD56), and generally poor response to ...
... Nine previously reported cases have been identified on literature review (see references below) with a broad age of onset (7-68 years, median 39), many with monocytic differentiation, frequently aberrant immunophenotypic antigen expression (often with CD7 and/or CD56), and generally poor response to ...
Investigating sea turtle migration using DNA markers
... is provided by genetic studies at other stages of marine turtle life history. Migrational corridors and feeding grounds of sea turtles are ofien subject to human activities that result in a high mortality among feeding aggregates. Such anthropogenic factors include the direct harvesting of turtles f ...
... is provided by genetic studies at other stages of marine turtle life history. Migrational corridors and feeding grounds of sea turtles are ofien subject to human activities that result in a high mortality among feeding aggregates. Such anthropogenic factors include the direct harvesting of turtles f ...
