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Topic 1 – Classification, variation and inheritance
Topic 1 – Classification, variation and inheritance

... Female gametes – egg cells in both animals and plants Gametes are different from other body cells because they only have one copy of each chromosome (i.e 23 chromosomes in their nucleus…not 46) Gametes only have one allele for each gene In sexual reproduction the male and female gametes fuse togeth ...
No Slide Title
No Slide Title

... (Y chromosome -carries the information which produces maleness in humans. A hormone (TDF) is released in human males at 6/7th weeks gestation. The presence or absence of this protein determines the sex of the child. Disjunction disorders - Sex chromosomes do not separate properly during meiosis. Spe ...
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File

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< 1 ... 369 370 371 372 373 374 375 376 377 ... 619 >

Dominance (genetics)



Dominance in genetics is a relationship between alleles of one gene, in which the effect on phenotype of one allele masks the contribution of a second allele at the same locus. The first allele is dominant and the second allele is recessive. For genes on an autosome (any chromosome other than a sex chromosome), the alleles and their associated traits are autosomal dominant or autosomal recessive. Dominance is a key concept in Mendelian inheritance and classical genetics. Often the dominant allele codes for a functional protein whereas the recessive allele does not.A classic example of dominance is the inheritance of seed shape, for example a pea shape in peas. Peas may be round, associated with allele R or wrinkled, associated with allele r. In this case, three combinations of alleles (genotypes) are possible: RR, Rr, and rr. The RR individuals have round peas and the rr individuals have wrinkled peas. In Rr individuals the R allele masks the presence of the r allele, so these individuals also have round peas. Thus, allele R is dominant to allele r, and allele r is recessive to allele R. This use of upper case letters for dominant alleles and lower caseones for recessive alleles is a widely followed convention.More generally, where a gene exists in two allelic versions (designated A and a), three combinations of alleles are possible: AA, Aa, and aa. If AA and aa individuals (homozygotes) show different forms of some trait (phenotypes), and Aa individuals (heterozygotes) show the same phenotype as AA individuals, then allele A is said to dominate or be dominant to or show dominance to allele a, and a is said to be recessive to A.Dominance is not inherent to an allele. It is a relationship between alleles; one allele can be dominant over a second allele, recessive to a third allele, and codominant to a fourth. Also, an allele may be dominant for a particular aspect of phenotype but not for other aspects influenced by the same gene. Dominance differs from epistasis, a relationship in which an allele of one gene affects the expression of another allele at a different gene.
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