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Transposable elements: Barbara McClintock and early experiments
Transposable elements: Barbara McClintock and early experiments

... between Wx+ and the centromere, and she called this hotspot Dissociation (Ds). She predicted that breakage at Ds resulted in an acentric fragment containing the C-I, Bz+ and Wx+ genes and that this fragment was lost during development of the kernel. The variegation was heritable, and McClintock mapp ...
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By Lydia Bosman, MSc (Agric), and Rulien Grobler, BSc (Agric),
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Sex-linked Traits - Perry Local Schools
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Mendel and Inheritance - University of Missouri
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SBI 3C genetics Study Guide (SPRING 2015)
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Document
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BIO41 CH23.pptx

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1. Explain what is meant by the “modern synthesis”.

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1. The I gene determines the synthesis of a repressor molecule
1. The I gene determines the synthesis of a repressor molecule

... Another way of labeling mutants of the operator is to denote that they lead to a constitutive phenotype; lacO– (or a–) can also be written as lacOc. There are also mutations of the repressor that fail to bind inducer (allolactose) as opposed to fail to bind DNA. These two classes have quite differen ...
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Dominance (genetics)



Dominance in genetics is a relationship between alleles of one gene, in which the effect on phenotype of one allele masks the contribution of a second allele at the same locus. The first allele is dominant and the second allele is recessive. For genes on an autosome (any chromosome other than a sex chromosome), the alleles and their associated traits are autosomal dominant or autosomal recessive. Dominance is a key concept in Mendelian inheritance and classical genetics. Often the dominant allele codes for a functional protein whereas the recessive allele does not.A classic example of dominance is the inheritance of seed shape, for example a pea shape in peas. Peas may be round, associated with allele R or wrinkled, associated with allele r. In this case, three combinations of alleles (genotypes) are possible: RR, Rr, and rr. The RR individuals have round peas and the rr individuals have wrinkled peas. In Rr individuals the R allele masks the presence of the r allele, so these individuals also have round peas. Thus, allele R is dominant to allele r, and allele r is recessive to allele R. This use of upper case letters for dominant alleles and lower caseones for recessive alleles is a widely followed convention.More generally, where a gene exists in two allelic versions (designated A and a), three combinations of alleles are possible: AA, Aa, and aa. If AA and aa individuals (homozygotes) show different forms of some trait (phenotypes), and Aa individuals (heterozygotes) show the same phenotype as AA individuals, then allele A is said to dominate or be dominant to or show dominance to allele a, and a is said to be recessive to A.Dominance is not inherent to an allele. It is a relationship between alleles; one allele can be dominant over a second allele, recessive to a third allele, and codominant to a fourth. Also, an allele may be dominant for a particular aspect of phenotype but not for other aspects influenced by the same gene. Dominance differs from epistasis, a relationship in which an allele of one gene affects the expression of another allele at a different gene.
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