Slide 1
... DNA replication is amazing error-free – 1 error per billion bases copied; – This is comparable to copying 2400 “Life in the Universe” books with only one word spelled wrong. ...
... DNA replication is amazing error-free – 1 error per billion bases copied; – This is comparable to copying 2400 “Life in the Universe” books with only one word spelled wrong. ...
Mutations - ScienceGeek.net Homepage
... – Mutations that occur in germ cells (sperm, eggs) are passed on to offspring – Mutations in somatic (body) cells may be harmless, or may result in disease such as cancer ...
... – Mutations that occur in germ cells (sperm, eggs) are passed on to offspring – Mutations in somatic (body) cells may be harmless, or may result in disease such as cancer ...
Multidimensional Analysis
... • Feature selection: a selected group of genes may be optimal (t-test) • Independent validation: you must test the classifier on samples that were not used for feature selection or for building the classifier (training set - test set or leave-oneout crossvalidation) ...
... • Feature selection: a selected group of genes may be optimal (t-test) • Independent validation: you must test the classifier on samples that were not used for feature selection or for building the classifier (training set - test set or leave-oneout crossvalidation) ...
EGAN - iPlant Pods
... Key focus- interactive analysis of sets of genes – User identifies the sets interactively – Enrichment -- uses Fishers exact test to see whether genes in a pathway are “overrepresented” relative to chance selection. Based on hypergeometric distribution, an n choose k sampling distribution – Gene set ...
... Key focus- interactive analysis of sets of genes – User identifies the sets interactively – Enrichment -- uses Fishers exact test to see whether genes in a pathway are “overrepresented” relative to chance selection. Based on hypergeometric distribution, an n choose k sampling distribution – Gene set ...
Human Genetics
... Why Focus on Disorders? • Humans have thousands of traits that are common to all individuals. – List some examples ...
... Why Focus on Disorders? • Humans have thousands of traits that are common to all individuals. – List some examples ...
Genetics
... • Transposons are small pieces of DNA that move readily from one site on bacterial chromosome to another or from bacterial chromosome to plasmid. • They carry antibiotic resistance genes. • Transfer of transposons on plasmids to other bacteria by conjugation contributes to antibiotic resistance. ...
... • Transposons are small pieces of DNA that move readily from one site on bacterial chromosome to another or from bacterial chromosome to plasmid. • They carry antibiotic resistance genes. • Transfer of transposons on plasmids to other bacteria by conjugation contributes to antibiotic resistance. ...
cladogram analysis
... 1. (__________________________)- one organism is harmed while the other benefits 2. (__________________________)- both organisms benefit 3. (__________________________)- flea and a cat. 4. (__________________________)- buffalo and an insect eating bird 5. (__________________________)- organisms livi ...
... 1. (__________________________)- one organism is harmed while the other benefits 2. (__________________________)- both organisms benefit 3. (__________________________)- flea and a cat. 4. (__________________________)- buffalo and an insect eating bird 5. (__________________________)- organisms livi ...
genetic sleuths unmask secrets of big tomatoes
... A true wild tomato may have only two to four of these. "Somehow, something made the plant start making these compartments, and by making more compartments, you can get larger fruit." GENE TROLL To understand this process, Tanksley first mapped the tomato's roughly 30,000 genes, looking for differenc ...
... A true wild tomato may have only two to four of these. "Somehow, something made the plant start making these compartments, and by making more compartments, you can get larger fruit." GENE TROLL To understand this process, Tanksley first mapped the tomato's roughly 30,000 genes, looking for differenc ...
leaflet - University of Nottingham
... identify changes in DNA which predispose to pre-eclampsia. It’s called the InterPregGen study because it’s international, it’s about pregnancy, and it’s studying genes. There is good evidence for inherited factors – a woman whose mother had preeclampsia is three times more likely than other women to ...
... identify changes in DNA which predispose to pre-eclampsia. It’s called the InterPregGen study because it’s international, it’s about pregnancy, and it’s studying genes. There is good evidence for inherited factors – a woman whose mother had preeclampsia is three times more likely than other women to ...
View Ch. 13 PowerPoint here.
... • Based on genetic recombination (crossing over) between genes • If crossover occurs, parental alleles are recombined producing recombinant gametes • Genes close together on a single chromosome are said to be linked. • As physical distance on a chromosome increases, so does the probability of recomb ...
... • Based on genetic recombination (crossing over) between genes • If crossover occurs, parental alleles are recombined producing recombinant gametes • Genes close together on a single chromosome are said to be linked. • As physical distance on a chromosome increases, so does the probability of recomb ...
Pizzly Analysis: Directions: Read this article. You will then need to
... species or different genera generally don't have the same bad recessive alleles, and so there's not a high chance of a pair turning up. (Alleles are different versions of the same gene.) But over time, as the hybrids mate randomly, those harmful genes will come out of hiding and make the offspring l ...
... species or different genera generally don't have the same bad recessive alleles, and so there's not a high chance of a pair turning up. (Alleles are different versions of the same gene.) But over time, as the hybrids mate randomly, those harmful genes will come out of hiding and make the offspring l ...
Mayr, mathematics and the study of evolution
... an input or output of genes, as the adding of certain beans to a beanbag and the withdrawing of others.” [1]. Mayr was, however, criticizing textbook simplifications, rather than the actual work of the three pioneers. Far from treating gene frequency changes as analogous to the consequence of beans ...
... an input or output of genes, as the adding of certain beans to a beanbag and the withdrawing of others.” [1]. Mayr was, however, criticizing textbook simplifications, rather than the actual work of the three pioneers. Far from treating gene frequency changes as analogous to the consequence of beans ...
Population Genetics 5: Mutation pressure Mutation pressure
... • if mutation rates change the equilibrium state will change • if island has non-equilibrium GC content mutation pressure will cause it to evolve to a new equilibrium. • process of evolution to a new GC equilibrium is called mutational amelioration • amelioration is much slower than in our model ...
... • if mutation rates change the equilibrium state will change • if island has non-equilibrium GC content mutation pressure will cause it to evolve to a new equilibrium. • process of evolution to a new GC equilibrium is called mutational amelioration • amelioration is much slower than in our model ...
NonMendelian Inheritance Patterns
... yellow. But what happens when they appear mottled/streaked? ...
... yellow. But what happens when they appear mottled/streaked? ...
CHAPTER 1 Genetics An Introduction
... Sources of Genetic Variation Genetic differences between organisms arise from mutations, recombination and selection. All three are necessary for the process of evolution. a. Mutations (heritable changes in the genetic material) may be spontaneous or induced. Only those that escape the cell’s DNA r ...
... Sources of Genetic Variation Genetic differences between organisms arise from mutations, recombination and selection. All three are necessary for the process of evolution. a. Mutations (heritable changes in the genetic material) may be spontaneous or induced. Only those that escape the cell’s DNA r ...
CFA 03- Review Notes
... Tennessee SPI Objective: Analyze data on levels of variation within a population to make predictions about survival under particular environmental conditions. Variation refers to a variety or diversity of traits (different kinds) within any given population. Three causes of variation 1) Diversity ...
... Tennessee SPI Objective: Analyze data on levels of variation within a population to make predictions about survival under particular environmental conditions. Variation refers to a variety or diversity of traits (different kinds) within any given population. Three causes of variation 1) Diversity ...
CP Biology
... We know that males have XY sex chromosomes, and they seem to function just fine, so they must be able to survive with only 1 X chromosome. Females, however, have XX as sex chromosomes, two of them! So, do we really need two, or do females have an extra? The answer was discovered in 1961 by Mary Lyon ...
... We know that males have XY sex chromosomes, and they seem to function just fine, so they must be able to survive with only 1 X chromosome. Females, however, have XX as sex chromosomes, two of them! So, do we really need two, or do females have an extra? The answer was discovered in 1961 by Mary Lyon ...
Recombinant DNA Technology (b)
... found in pairs, with A & T and G & C Double helix sequence and number of bases creates the diversity ...
... found in pairs, with A & T and G & C Double helix sequence and number of bases creates the diversity ...
DNA and RNA
... conversion of the information encoded in a gene first into messenger RNA and then to a protein gene regulation ability of an organism to control which genes are transcribed in response to the environment operon section of DNA containing genes for proteins required for a specific metabolic pathway co ...
... conversion of the information encoded in a gene first into messenger RNA and then to a protein gene regulation ability of an organism to control which genes are transcribed in response to the environment operon section of DNA containing genes for proteins required for a specific metabolic pathway co ...
Lecture ppt Slides
... Targeted insertion results in cells that confer neomycinresistance and do not harbor the tk+ gene (confers ganciclovir-resistance). Cells can be isolated selectively. ...
... Targeted insertion results in cells that confer neomycinresistance and do not harbor the tk+ gene (confers ganciclovir-resistance). Cells can be isolated selectively. ...
Chapter 6
... • Gregor Mendel was the first person to apply statistical methods to the study of inheritance. Mendel observed that heterozygotes do not express recessive traits, but can pass on these traits to their offspring. • Mendel’s law of segregation states that all individuals have two copies of each factor ...
... • Gregor Mendel was the first person to apply statistical methods to the study of inheritance. Mendel observed that heterozygotes do not express recessive traits, but can pass on these traits to their offspring. • Mendel’s law of segregation states that all individuals have two copies of each factor ...
Biol 303 levels and types of selection
... Individuals express phenotypes, ie. a gene is selected +/- because of effects on phenotype. Individuals express phenotypes, so alleles at one locus are selected for or against on the basis of the complete genetic “background” formed by all the other loci in that individual. Emphasis on bearer, in th ...
... Individuals express phenotypes, ie. a gene is selected +/- because of effects on phenotype. Individuals express phenotypes, so alleles at one locus are selected for or against on the basis of the complete genetic “background” formed by all the other loci in that individual. Emphasis on bearer, in th ...
Genetic Engineering / Recombinant DNA technology Genetic
... Genetic engineering is a broad term referring to manipulation of an organisms’ nucleic acid. Organisms whose genes have been artificially altered for a desired affect is often called genetically modified organism (GMO). Recombinant DNA technology (rDNA) is technology that is used to cut a known DNA ...
... Genetic engineering is a broad term referring to manipulation of an organisms’ nucleic acid. Organisms whose genes have been artificially altered for a desired affect is often called genetically modified organism (GMO). Recombinant DNA technology (rDNA) is technology that is used to cut a known DNA ...
L - Centre for Genomic Regulation
... There is no limit on the number of orthologs or paralogs that a given gene can have (when more than one ortholog exist, there is nothing such as “the true ortholog”) Many-to-Many orthology relationships do exist (co-orthology) No limit on how ancient/recent is the ancestral relationship of orthologs ...
... There is no limit on the number of orthologs or paralogs that a given gene can have (when more than one ortholog exist, there is nothing such as “the true ortholog”) Many-to-Many orthology relationships do exist (co-orthology) No limit on how ancient/recent is the ancestral relationship of orthologs ...
The next evolutionary synthesis: from Lamarck and Darwin to
... The book is thus situated within the general context of systems biology and bioinformatics in the sense of the informatics of biology rather than its usual meaning (computational sequence analysis), it is thus a refreshingly modern read. The heart of the book is its analysis of the diversity of gene ...
... The book is thus situated within the general context of systems biology and bioinformatics in the sense of the informatics of biology rather than its usual meaning (computational sequence analysis), it is thus a refreshingly modern read. The heart of the book is its analysis of the diversity of gene ...