SHORT COMMUNICATION One-step multiplex RT-PCR
... The patient who was negative for BCR/ABL had clinical features and peripheral blood film suggestive of chronic myeloproliferative disease. Her condition was complicated by carcinoma of the breast that developed later. The use of conventional cytogenetic analysis has complemented PCR at initial diagn ...
... The patient who was negative for BCR/ABL had clinical features and peripheral blood film suggestive of chronic myeloproliferative disease. Her condition was complicated by carcinoma of the breast that developed later. The use of conventional cytogenetic analysis has complemented PCR at initial diagn ...
Package `CPBayes`
... trait-specific univariate association p-value across all the traits are > 0.1. The trait-specific univariate association p-values are obtained using the beta-hat and standard error for each trait. Each of the SNPs selected in this way is either weakly or not associated with any of the phenotypes (nu ...
... trait-specific univariate association p-value across all the traits are > 0.1. The trait-specific univariate association p-values are obtained using the beta-hat and standard error for each trait. Each of the SNPs selected in this way is either weakly or not associated with any of the phenotypes (nu ...
Genomic rearrangements account for more than one
... The screening for BRCA1 mutations in breast and/or ovarian cancer families has become more and more complex due to the occurrence of different mutation types, such as major genomic rearrangements, detectable only when specific technical approaches are employed. Here we demonstrate that the informati ...
... The screening for BRCA1 mutations in breast and/or ovarian cancer families has become more and more complex due to the occurrence of different mutation types, such as major genomic rearrangements, detectable only when specific technical approaches are employed. Here we demonstrate that the informati ...
About and Key Statistics - American Cancer Society
... A great deal of research has gone into figuring out how certain DNA changes in retinal cells cause them to become cancerous. Scientists understand these changes better for retinoblastoma than for most other cancer types. Although probably still years away, researchers hope that this understanding wi ...
... A great deal of research has gone into figuring out how certain DNA changes in retinal cells cause them to become cancerous. Scientists understand these changes better for retinoblastoma than for most other cancer types. Although probably still years away, researchers hope that this understanding wi ...
A Novel Two Domain-Fusion Protein in Cyanobacteria with
... members of an extended CAB/ELIP/HLIP superfamily of distantly related polypeptides, which have between one and four transmembrane helices (TMH). This superfamily includes the single TMH, high-light-inducible proteins (Hlips), found in cyanobacteria that are induced by various stress conditions, incl ...
... members of an extended CAB/ELIP/HLIP superfamily of distantly related polypeptides, which have between one and four transmembrane helices (TMH). This superfamily includes the single TMH, high-light-inducible proteins (Hlips), found in cyanobacteria that are induced by various stress conditions, incl ...
Tibetan and Andean Patterns of Adaptation to High
... ling for environmental influences can reveal the influence of unknown genes. A shortcoming of this approach is the implicit assumption of genetic homogeneity at relevant loci in both samples and the explicit assumption that environmental sources of variation are known and uniform. Actually, many lo ...
... ling for environmental influences can reveal the influence of unknown genes. A shortcoming of this approach is the implicit assumption of genetic homogeneity at relevant loci in both samples and the explicit assumption that environmental sources of variation are known and uniform. Actually, many lo ...
PowerPoint
... PhenomeR aims to build hierarchical ontology class structures and entities of all observed PID phenotypic terms that can be further used as integrated knowledgebase query interface - SPARQL Protocol and RDF Query Language (SPARQL) for screening and implementing algorithms to compile data from multip ...
... PhenomeR aims to build hierarchical ontology class structures and entities of all observed PID phenotypic terms that can be further used as integrated knowledgebase query interface - SPARQL Protocol and RDF Query Language (SPARQL) for screening and implementing algorithms to compile data from multip ...
Argonaute2 Is Essential for Mammalian
... embryonic germ layers: ectoderm, endoderm, and mesoderm. The gene Brachyury is essential for mesoderm development, and shorttail mice, which were later found to be carrying a Brachyury mutation, have been known since 1927. In this study, we found a genetic interaction between Brachyury and another g ...
... embryonic germ layers: ectoderm, endoderm, and mesoderm. The gene Brachyury is essential for mesoderm development, and shorttail mice, which were later found to be carrying a Brachyury mutation, have been known since 1927. In this study, we found a genetic interaction between Brachyury and another g ...
Yan D et al., 2014 - Drosophila RNAi Screening Center
... phenotypic data are available to date. For example, knockdown of CG11266 (referred to as igru thereafter (see Experimental Procedures for details)), a proposed splicing factor, resulted in an almost complete depletion of germline cells (Figure 3E) suggesting a role for igru in GSC maintenance. We se ...
... phenotypic data are available to date. For example, knockdown of CG11266 (referred to as igru thereafter (see Experimental Procedures for details)), a proposed splicing factor, resulted in an almost complete depletion of germline cells (Figure 3E) suggesting a role for igru in GSC maintenance. We se ...
inquiry into primary producer access to gene technology
... encouragement of certain externality generating activities and they highlight possible reasons why market forces alone might not result in the highest possible long-term growth”. The new growth theories also help to differentiate government expenditure on research and development compared with other ...
... encouragement of certain externality generating activities and they highlight possible reasons why market forces alone might not result in the highest possible long-term growth”. The new growth theories also help to differentiate government expenditure on research and development compared with other ...
Composite Beef Breeds - FSA3057 - University of Arkansas Division
... composites is influenced by inbreeding. If no inbreeding is practiced, the heterosis is retained in composites for several generations, as shown in research results from the Meat Animal Research Center data (Table 1). Table 2 below demonstrates the theory behind heterosis retention in composite line ...
... composites is influenced by inbreeding. If no inbreeding is practiced, the heterosis is retained in composites for several generations, as shown in research results from the Meat Animal Research Center data (Table 1). Table 2 below demonstrates the theory behind heterosis retention in composite line ...
CATARACT Michael E Bernays BVSc (Hons) FACVSc Veterinary
... A cataract is an opacity of a structure inside the eye called the lens. The lens is oval in cross section and is found behind the iris and in front of the vitreous. It is made up of living cells which replicate themselves from early embryonic life and continue to do so for the whole of an animal’s l ...
... A cataract is an opacity of a structure inside the eye called the lens. The lens is oval in cross section and is found behind the iris and in front of the vitreous. It is made up of living cells which replicate themselves from early embryonic life and continue to do so for the whole of an animal’s l ...
Genetic balancers
... Complementation between two lethal mutations can be assayed by performing a cross to construct animals heterozygous for both lethals and the same marker mutation, and scoring for marker homozygotes. Presence of these homozygotes indicates complementation, and absence indicates failure to complement. ...
... Complementation between two lethal mutations can be assayed by performing a cross to construct animals heterozygous for both lethals and the same marker mutation, and scoring for marker homozygotes. Presence of these homozygotes indicates complementation, and absence indicates failure to complement. ...
Facts about Charcot-Marie-Tooth Disease
... of CMT that manifests during infancy or early childhood. Although there's no cure for CMT, there are treatments that can be used to effectively manage its symptoms. Those treatments, described here along with a general overview of CMT, have allowed many people with the disease to lead active, produc ...
... of CMT that manifests during infancy or early childhood. Although there's no cure for CMT, there are treatments that can be used to effectively manage its symptoms. Those treatments, described here along with a general overview of CMT, have allowed many people with the disease to lead active, produc ...
M.Sc., Biotechnology - Alagappa University
... them. It is also concerned with the entire range of life forms beginning from the obligate intracellular parasites such as viruses to simplest of prokaryotic organisms to complex human beings. Biochemistry has become the fundamental language for all the biological sciences as life depends on biochem ...
... them. It is also concerned with the entire range of life forms beginning from the obligate intracellular parasites such as viruses to simplest of prokaryotic organisms to complex human beings. Biochemistry has become the fundamental language for all the biological sciences as life depends on biochem ...
PDF
... the contrasts in Table 1, specifically with c = 1 and c = 1/(1 + F ), respectively. Therefore, by implementing the effective gene content c we have actually made our model to capture the correlation between alleles that the average excesses account for. Further, using the relationship between the two ...
... the contrasts in Table 1, specifically with c = 1 and c = 1/(1 + F ), respectively. Therefore, by implementing the effective gene content c we have actually made our model to capture the correlation between alleles that the average excesses account for. Further, using the relationship between the two ...
Hereditary hemorrhagic telangiectasia: genetics and molecular
... both genes. Although less common than missense mutations in ENG and ACVRL1, the proportion of mutations causing a truncating frameshift or stop codon (i.e., indels and non-sense mutations) are more frequent in ENG than in ACVRL1 (Lesca et al., 2004 3 ). No common mutation “hotspots” have been observ ...
... both genes. Although less common than missense mutations in ENG and ACVRL1, the proportion of mutations causing a truncating frameshift or stop codon (i.e., indels and non-sense mutations) are more frequent in ENG than in ACVRL1 (Lesca et al., 2004 3 ). No common mutation “hotspots” have been observ ...
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... better substrate for B-galactosidase than lactose (Jobe 40 The novel lacIZYA operon (Table 1) can be inserted in any plasmid, or it can be inserted into any microbial and Bourgeois, supra), and is itself rapidly converted to chromosome to improve control of heterologous gene glucose and galactose. e ...
... better substrate for B-galactosidase than lactose (Jobe 40 The novel lacIZYA operon (Table 1) can be inserted in any plasmid, or it can be inserted into any microbial and Bourgeois, supra), and is itself rapidly converted to chromosome to improve control of heterologous gene glucose and galactose. e ...
Statistical analysis of simple repeats in the human genome
... elements. Mobile elements include DNA transposons, short and long interspersed elements (SINEs and LINEs), and processed pseudogenes [4,5]. Why should we be interested in repetitive DNA? Tandem repeats with 1–3 base motif can differ in repeat number among individuals; therefore, they are used as gen ...
... elements. Mobile elements include DNA transposons, short and long interspersed elements (SINEs and LINEs), and processed pseudogenes [4,5]. Why should we be interested in repetitive DNA? Tandem repeats with 1–3 base motif can differ in repeat number among individuals; therefore, they are used as gen ...
pdf
... This is explained by crossing over between the gene pairs during meiosis in the parents. Let’s think about the general recombination shown in Fig. 8.1 in this context. The two chromosomes outlined in the figure are in a heterozygous parent, with the wild type alleles for genes A and B (A+ and B+) ar ...
... This is explained by crossing over between the gene pairs during meiosis in the parents. Let’s think about the general recombination shown in Fig. 8.1 in this context. The two chromosomes outlined in the figure are in a heterozygous parent, with the wild type alleles for genes A and B (A+ and B+) ar ...
Oakley
... co-opted. Namely, he distinguishes processes of terminal cell differentiation (e.g. the direct regulation by eyeless of eye structural genes [33]) from processes of upstream pattern formation (e.g. the control that eyeless has over early morphogenetic processes, as demonstrated by ectopic eye induct ...
... co-opted. Namely, he distinguishes processes of terminal cell differentiation (e.g. the direct regulation by eyeless of eye structural genes [33]) from processes of upstream pattern formation (e.g. the control that eyeless has over early morphogenetic processes, as demonstrated by ectopic eye induct ...
The murine homologue of HIRA, a DiGeorge
... cDNA clones 12B and 12E represent splice variants with exons 3A and 11A Two out of the seven Hira cDNAs (clones 12B and 12E) contain non-canonical sequences (Fig. 1A). To investigate whether these cDNAs represent valid transcripts, we partially characterized the genomic organization of the murine Hi ...
... cDNA clones 12B and 12E represent splice variants with exons 3A and 11A Two out of the seven Hira cDNAs (clones 12B and 12E) contain non-canonical sequences (Fig. 1A). To investigate whether these cDNAs represent valid transcripts, we partially characterized the genomic organization of the murine Hi ...
Introductory genetics for veterinary students
... and q alleles will be alternatively “fixed” in the alternate F0 lines? Hence, that the QTL genotype of all F1 animals is the same? Especially when this is not the case for the SNP or microsatellite markers. This has lead to many erroneous conclusions of imprinted QTL in animal genetics ...
... and q alleles will be alternatively “fixed” in the alternate F0 lines? Hence, that the QTL genotype of all F1 animals is the same? Especially when this is not the case for the SNP or microsatellite markers. This has lead to many erroneous conclusions of imprinted QTL in animal genetics ...
Review Article
... Construction of an in-frame deletion in the chromosomal bvgA gene in B. pertussis prevented transcription from the fhaB and ptxA promoters (Roy et al., 1989). Thus, although BvgA cannot activate theptx promoter in E. coli, it is clearly required for activation of the ptx operon in B. pertussis. This ...
... Construction of an in-frame deletion in the chromosomal bvgA gene in B. pertussis prevented transcription from the fhaB and ptxA promoters (Roy et al., 1989). Thus, although BvgA cannot activate theptx promoter in E. coli, it is clearly required for activation of the ptx operon in B. pertussis. This ...