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The dystrophin / utrophin homologues in Drosophila and in sea urchin
The dystrophin / utrophin homologues in Drosophila and in sea urchin

... proteins transcribed from internal promoters located further downstream, and lack important domains of dystrophin. Several other genes, encoding evolutionarily related proteins, have been identi®ed. To study the evolution of the DMD gene and the signi®cance of its various products, we have searched ...
Congenital hereditary cataracts
Congenital hereditary cataracts

... published recently for a mild pulverulent cataract mutant in mouse (opaque flecks in the lens, Opj; Lyon et al., 2003). The point mutation affects the basic region of the DNA-binding domain. In general, Maf binds as homo- or heterodimer to two known Maf responsive elements (MAREs), with varying affi ...
Statistic and Analytical Strategies for HLA Data
Statistic and Analytical Strategies for HLA Data

... For example, if we want to understand the distribution of HLA-B*27 in healthy residents of a certain region and the frequency of the HLA-B*27 gene in patients with ankylosing arthritis, how many individuals should be included in the sample? According to the principle of the hypothesis test, if the s ...
CAIcal: A combined set of tools to assess codon usage adaptation
CAIcal: A combined set of tools to assess codon usage adaptation

... used for translation. The query sequences must be DNA or RNA sequences in fasta format. The server first checks whether the query sequences are a DNA or RNA region that codifies a protein. The reference set required to calculate the CAI can be introduced in a variety of formats, including that of th ...
View PDF - G3: Genes | Genomes | Genetics
View PDF - G3: Genes | Genomes | Genetics

... colonies remain unstained. Likewise, the sporulated colonies of the S. japonicus var. versatilis stock that we employed for our cell differentiation study stained with iodine vapors (Yu et al. 2013). By exploiting this procedure, we recently described isolation of switching-incapable (designated “he ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... Association of Genetic Polymorphism in cyp19a Gene in Patients with Polycystic Ovarian… Diamati-kandarakis et al (2009)12 described the same gene CYP19a polymorphism in Greek population with 50 PCOS subjects and reported 58% were heterozygous carriers of the polymorphic allele and 8% carried A2 all ...
S4O3 Pretest 2015-2016
S4O3 Pretest 2015-2016

... of damage to the bacterium, what type of mutation would you choose? Would you locate it in the repressor, the promoter, or somewhere else? Give reasons for your answer. Agrobacterium tumefaciens is a bacterium that causes crown gall disease, a tumorous growth on the growing tip of certain plants. Th ...
Expression of p53 Target Genes in the Early Phase of Long
Expression of p53 Target Genes in the Early Phase of Long

... Thus, which functional consequences might the brief activation of p53 have? The control of the transcriptional activity of p53 is considered crucial for determining which p53 response is activated [5]. In this paper, we describe the expression of p53-related genes in the rat hippocampal CA1 area in ...
A Fitness-Independent Evolvability Measure for Evolutionary
A Fitness-Independent Evolvability Measure for Evolutionary

... For our developmental model for cellular growth, more than one system property can be chosen as the phenotype of the system. For instance, the morphology (shape) of the cellular structure when the growing process is complete can be seen as the phenotype. Another option is the cellular behaviors resu ...
Efficient Ends-Out Gene Targeting In Drosophila
Efficient Ends-Out Gene Targeting In Drosophila

... marker with a GFP marker, or replacing wild type loxP sites with other lox site variants. pRK2 was generated by adding GMR enhancer into the BsiWI site of pRK1. In addition, enzyme sites in 5' MCS are ordered similarly to the popular pUAST vector. Thus, when pRK1 or pRK2 is used for making knock-in ...
What stay-green mutants tell us about nitrogen remobilization in leaf
What stay-green mutants tell us about nitrogen remobilization in leaf

... are reported to have been isolated. The gene responsible for the stay-green phenotype in grasses and legumes has not yet been cloned but a fair amount is known about it. Pigment metabolism in senescing leaves of the Festuca–Lolium stay-green mutant is clearly disturbed and is consistent with a block ...
Introduction
Introduction

... hypothesized to be • Dosage effect of BMP-15 or GDF-9 protein • Due to a dominant negative effect of the BMP-15 pro-peptide interfering with the formation of GDF-9 homodimers, BMP-15 homodimers, and/or GDF-9/BMP-15 heterodimers. – Because antibodies directed against the mature region of the protein ...
Genetic studies of psoriasis and psoriatic arthritis
Genetic studies of psoriasis and psoriatic arthritis

... region on chromosome 3q21. Another purpose was to investigate whether several autoimmuneassociating genes and genomic regions are susceptibility factors for psoriasis/psoriatic arthritis. Association studies on a psoriatic arthritis case-control material revealed an association with a marker in the ...
RESISTANCE AS A RESPONSE TO STRESS
RESISTANCE AS A RESPONSE TO STRESS

... mutation, i.e. one nucleotide in the gene’s coding region is substituted with a different nucleotide so that a different amino acid is encoded for at a specific position and this change causes the gene product to have a different three-dimensional structure, can result in resistance in several ways. ...
You Light Up My Life
You Light Up My Life

... Earlobe Variation • Whether a person is born with attached or detached earlobes depends on a single gene • Gene has two molecular forms (alleles) ...
Darwin and the Origin of Interspecific Genetic Incompatibilities.
Darwin and the Origin of Interspecific Genetic Incompatibilities.

Sample Extra Credit Paper
Sample Extra Credit Paper

... Fatal Familial Insomnia is a complex disease, as are all prion diseases. So little is known about prion diseases and fully understanding their mechanisms will take an incredible amount of research in terms of time and money. It is important that FFI continues to be researched along with all prion di ...
lecture 20
lecture 20

Phytoalexin-Deficient Mutants of Arabidopsis Reveal That
Phytoalexin-Deficient Mutants of Arabidopsis Reveal That

... camalexin synthesis in response to PsmES4326 infection, but not in response to Cochliobolus carbonum infection, indicating that PAD4 has a regulatory function. PADI, PAD2, PAD3and PAD4 are all required for resistance to the eukaryotic biotroph Peronospora parasitica. The pad4-1 mutation caused the m ...
day one: introduction to drosophila
day one: introduction to drosophila

... To get information about how the trait is determined, individuals homozygous for different forms of the trait must be crossed. Their offspring are known as F1s and should be heterozygous (with a different form of genetic information for the trait from each parent). Seeing which form of the trait is ...
Document
Document

... • Subgroup analysis and multiple testing • Random error • Poorly matched control group • Failure to attempt study replication ...
Compound leaves: equal to the sum of their parts?
Compound leaves: equal to the sum of their parts?

... The major light gathering organ in most plants is the leaf. Evolution has produced a variety of leaves with different shapes, sizes and arrangements that reflect the diverse conditions that plants grow in. Recently, significant progress has been made in understanding the molecular mechanisms that re ...
Document
Document

... In this exercise, we will utilize the UCSC Genome Browser to view a refined whole genome alignment of orangutan, mouse, dog, and opossum genomes to human. This alignment is produced by Multiz, a program that utilizes pairwise whole genome alignments of many species and, using a phylogenetic tree, im ...
Slide 1
Slide 1

... mutations because they shift the “reading frame” of the genetic message. Frameshift mutations can change every amino acid that follows the point of the mutation and can alter a protein so much that it is unable to perform its normal functions. ...
Inheritance of the height of plants and number of leaves by hybrid
Inheritance of the height of plants and number of leaves by hybrid

... N o v e v a S . , T . L i d a n s k i , R . V a s s i l e v a , 1984, Interrelation of genes controlling quantitative characters in intercultivar tobacco hybrids. III. Inheritance of leaf width. Genet.Sel.17-5, pp369-376. Can. J. Genet. Cytol., 23-4, .585-59 N i z a m U d d i n , M . M . A . N e w a ...
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Genome (book)

Genome: The Autobiography of a Species in 23 Chapters is a 1999 popular science book by Matt Ridley, published by Fourth Estate.
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