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doc summer 2010 lecture 1 pg. 1-27
doc summer 2010 lecture 1 pg. 1-27

... Model organisms: small number of species whose genetic mechanisms are common either to all species or to a large group of related organisms MESSAGE: most genetic studies are performed on one of a limited number of model organisms, which have features that make them especially suited for scientific s ...
Page 1
Page 1

... ignore ethical / religious arguments ...
Stem Cells, Cancer, and Human Health
Stem Cells, Cancer, and Human Health

... Sex chromosomes – they control our sex 2 of our 46 one X, one that is either X or Y XX=female, XY=male ...
Ways to get from plant genomes to phenomes: via
Ways to get from plant genomes to phenomes: via

... of the alga Chlamydomonas reinhardtii and humans (both of which have flagellate cells, despite being otherwise very different) resulted in around 4,000 proteins shared by both species. When proteins present in Arabidopsis (a non-flagellate organism) were subtracted, 688 proteins remained. This set c ...
Aspects of Genetic and Genomics in Cancer Research
Aspects of Genetic and Genomics in Cancer Research

... • The etiology of cancer is multifactorial, with genetic, environmental, medical, and lifestyle factors interacting to produce a given malignancy. • The breakthroughs in high throughput genotyping technologies have made it possible for systematically identifying genes that are responsible for diseas ...
Sex Linked Traits
Sex Linked Traits

... Sex Linked Traits • When X and Y chromosomes meet at fertilization, each sex-linked gene on the X chromosome (whether recessive or dominant) becomes expressed in the phenotype. • This is because the Y chromosome does not possess alleles of any of these genes and cannot offer dominance to them. ...
MECHANISMS OF EVOLUTION
MECHANISMS OF EVOLUTION

Sex-linked, Mitochondrial Inheritance (Learning Objectives
Sex-linked, Mitochondrial Inheritance (Learning Objectives

... corresponding to an X-linked gene is a manifesting heterozygote (calico cats) ...
Name: Chapter 11: Introduction to Genetics Exam Matching: Match
Name: Chapter 11: Introduction to Genetics Exam Matching: Match

... 11. Many genes have more than two alleles and are therefore said to have . This does not mean that an individual can have more than two alleles. It only means that more than two possible alleles exist in a population. 12. Many traits are produced by the interaction of several genes. Traits controlle ...
Epistasis is not dominance.
Epistasis is not dominance.

... Codominance ...
Exam II
Exam II

... You have recently joined a lab that is directed by a rather eccentric lead scientist who has specialized his career in creatine kinase proteins (CK). These have been well characterized are made up of two subunits, which can be of two types. M (muscle type) is located on human chromosome 19, and B (b ...
rs8362 and rs6139034 was carried out. The results showed that only
rs8362 and rs6139034 was carried out. The results showed that only

... the candidate region on chromosome (Chr.) 20 in Thai population. TB is one of the three major infectious diseases worldwide and is known to be a complex disease that both genetic and environmental factors contribute to its development. A number of genetic studies in various populations have been car ...
Behavior Genetics
Behavior Genetics

... 1883 to describe the use of genetics for social planning. Galton, in other words, believed that selective "breeding" of the human species could guarantee that the "best" traits would remain in the human population while the "worst" traits could be eliminated. ...
trp operon – a repressible system
trp operon – a repressible system

... Gene regulation in eukaryotes is more complex than it is in prokaryotes because of: – the larger amount of DNA – the organization of chromatin – larger number of chromosomes – spatial separation of transcription and translation – mRNA processing – RNA stability – cellular differentiation in eukar ...
Concept 14.4: Microevolution is a change in a population`s gene pool.
Concept 14.4: Microevolution is a change in a population`s gene pool.

... Insects evolving resistance to pesticides ...
Paternal Age Risks
Paternal Age Risks

... syndrome, and osteogenesis imperfecta (“brittle bone” disease). Because there is such a variety of dominant genetic disorders that may be related to advanced paternal age, there is no single test available for prenatal diagnosis. An ultrasound can be performed to evaluate fetal growth and developmen ...
Classification of Genetic disorders:
Classification of Genetic disorders:

... In single gene disorders, individuals in regard to the abnormal gene are one of 3 groups: a heterozygote (carrying one mutated and one normal gene and thus affected in AD and not affected in AR disorders), a homozygote for the mutated gene (and thus affected in all cases), or a homozygote normal. Th ...
Non-Mendelian Inheritance and Exceptions to Mendel`s Rules
Non-Mendelian Inheritance and Exceptions to Mendel`s Rules

... • Inheritance of both copies of a gene (or a chromosome) from the same parent • Paternal UPD: inheritance of two copies of a gene/chromosome from the father and no copies from the mother. • Maternal UPD: inheritance of two copies of a gene/chromosome from the mother and no copies from the father. • ...
Name: DUE Date: ______ ____ period Chapter 17: From Gene to
Name: DUE Date: ______ ____ period Chapter 17: From Gene to

... ___________________________________________________________________________________________________________________ ___________________________________________________________________________________________________________________ 14. What is the advantage of the 5’ cap and poly A tail? ___________ ...
Genetic factors in aggression
Genetic factors in aggression

... of a gene-environment interaction. Further support for this interaction comes from a study into the MAOA gene. The gene was found to also interact with the environment as children with high levels of MAOA were more likely to be anti-social, but only if they’d been maltreated as children. This idea o ...
Genetics_PWRPOINT
Genetics_PWRPOINT

... As the Punnett square shows, TT, Tt, and tt are all possible genotypes for the height of the offspring. The offspring with the genotypes TT and Tt will have a phenotype of tall; the offspring with the genotype of tt will have a phenotype of short. If the two alleles are the same (TT or tt), the geno ...
Fundamental Principles of Variation
Fundamental Principles of Variation

... individuals that are alike in respect. _Genotype__-the genetic constitution of an individual organism, or of a group of organisms that are alike in that respect.. _Locus__-is a site on a chromosome, or more usually, the gene that occupies that site. _Allele__-is a particular form of a gene, usually ...
Evolution and Development
Evolution and Development

...   Together these data help infer the developmental genetic origins and histories of morphological characters. ...
TOC  - Genes | Genomes | Genetics
TOC - Genes | Genomes | Genetics

... Sequential Turnovers of Sex Chromosomes in African Clawed Frogs (Xenopus) Suggest Some Genomic Regions Are Good at Sex Determination Benjamin L. S. Furman and Ben J. Evans Sex determination is crucial for reproduction and it is interesting, therefore, when control of this fundamental process evolves ...
Genetics in Epidemiology - University of Pittsburgh
Genetics in Epidemiology - University of Pittsburgh

... • Genome-wide association studies (GWAS) – Hypothesis: common genetic variants (>5%) ; common diseases (traits) • Limited number of variants, each with a small effect ...
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Genome (book)

Genome: The Autobiography of a Species in 23 Chapters is a 1999 popular science book by Matt Ridley, published by Fourth Estate.
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