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Topic 5 Genetic Algorithms
Topic 5 Genetic Algorithms

... A genetic algorithm is a probabilistic search technique that computationally simulates the process of biological evolution. It mimics evolution in nature by repeatedly altering a population of candidate solutions until an optimal solution is found. In nature, each individual has characteristics dete ...
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... itrelf resistant. The morphological mutation segregates from acriflavine resistance in all Casey except one, designated au-6 mo (K19 KH160). (Since the +wo traits hove not been separated by recombination, on olternotive interpretation would be to conrider ocr-6 as a second-step mutant of m_o(KHlbO) ...
Welcome! 3/12/14
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... eyes (recessive). This gene is carried on the Xchromosome. Show the cross of a heterozygous 2-eyed female with a 4-eyed male. HOMEWORK/REMINDERS— All missing work DUE 3/28/14 END OF 3rd Quarter ...
Chapter 2: Introduction to Molecular Genetics
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... aligned in a germ cell, a cell that gives rise to eggs or sperm. Three DNA sequences are shown, labelled A, B and C. The capital letters represent the paternal alleles and the lower case letters represent the maternal alleles. The middle panel shows the physical process of recombination, which invol ...
Lecture Presentation to accompany Principles of Life
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... Mutations are changes in the nucleotide sequence of DNA that are passed on from one cell, or organism, to another. Mutations occur by a variety of processes. Errors that are not corrected by repair systems are passed on to daughter cells. Mutations are of two types: Somatic mutations occur in somati ...
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lecture_09(LP)

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... Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings ...
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... The pedigree below is for a genetic disease or abnormality. We do not yet know if it is dominant or recessive. We will determine if it is possible that the trait is autosomal recessive. If the trait were recessive, we could use the following designations for the alleles: A = not affected (dominant) ...
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... Bivalent is the structure containing all four chromatids (two representing each homologue) at the start of meiosis. Breakage and reunion describes the mode of genetic recombination, in which two DNA duplex molecules are broken at corresponding points and then rejoined crosswise (involving formation ...
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... chromosomes have been observed mostly as the sole chromosome aberration. Cells containing ring and/or giant markers varying in size or number can be observed in the same tumor sample. Telomeric associations are frequently seen. Molecular cytogenetic techniques indicate that both ring and giant marke ...
Punnet squares lecture rev 1-27
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... "forced themselves upon notice."  He saw that the traits were inherited in certain numerical ratios. ...
Educator's Resource Guide 4226  Biology 1 s 4-5
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... Segregation Mendel allowed members of the F1 generation to self-pollinate. The trait controlled by the recessive allele appeared in the next generation (F2) in about one-fourth of the offspring—even when it did not appear in the F1 generation. ▶ Separation of alleles is segregation. ▶ When gametes ( ...
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F 1 generation

...  A male receiving a single X-linked recessive allele from his mother will have the disorder.  A female must receive the allele from both parents to be affected. ...
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Chromosome



A chromosome (chromo- + -some) is a packaged and organized structure containing most of the DNA of a living organism. It is not usually found on its own, but rather is complexed with many structural proteins called histones as well as associated transcription (copying of genetic sequences) factors and several other macromolecules. Two ""sister"" chromatids (half a chromosome) join together at a protein junction called a centromere. Chromosomes are normally visible under a light microscope only when the cell is undergoing mitosis. Even then, the full chromosome containing both joined sister chromatids becomes visible only during a sequence of mitosis known as metaphase (when chromosomes align together, attached to the mitotic spindle and prepare to divide). This DNA and its associated proteins and macromolecules is collectively known as chromatin, which is further packaged along with its associated molecules into a discrete structure called a nucleosome. Chromatin is present in most cells, with a few exceptions - erythrocytes for example. Occurring only in the nucleus of eukaryotic cells, chromatin composes the vast majority of all DNA, except for a small amount inherited maternally which is found in mitochondria. In prokaryotic cells, chromatin occurs free-floating in cytoplasm, as these cells lack organelles and a defined nucleus. The main information-carrying macromolecule is a single piece of coiled double-stranded DNA, containing many genes, regulatory elements and other noncoding DNA. The DNA-bound macromolecules are proteins, which serve to package the DNA and control its functions. Chromosomes vary widely between different organisms. Some species such as certain bacteria also contain plasmids or other extrachromosomal DNA. These are circular structures in the cytoplasm which contain cellular DNA and play a role in horizontal gene transfer.Compaction of the duplicated chromosomes during cell division (mitosis or meiosis) results either in a four-arm structure (pictured to the right) if the centromere is located in the middle of the chromosome or a two-arm structure if the centromere is located near one of the ends. Chromosomal recombination during meiosis and subsequent sexual reproduction plays a vital role in genetic diversity. If these structures are manipulated incorrectly, through processes known as chromosomal instability and translocation, the cell may undergo mitotic catastrophe and die, or it may unexpectedly evade apoptosis leading to the progression of cancer.In prokaryotes (see nucleoids) and viruses, the DNA is often densely packed and organized. In the case of archaea by homologs to eukaryotic histones, in the case of bacteria by histone-like proteins. Small circular genomes called plasmids are often found in bacteria and also in mitochondria and chloroplasts, reflecting their bacterial origins.
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