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2. In vivo Maternal Haploid Induction in Maize
2. In vivo Maternal Haploid Induction in Maize

... Mechanism  of  in  vivo  maternal  haploid  induction     The  exact  sequence  of  events  underlying  maternal  haploid  induction  has  not  been  clearly  understood.   Several  hypotheses  were  proposed   to   explain  in  vivo  mater ...
Rearrangements in the Human T-Cell-Receptor Â
Rearrangements in the Human T-Cell-Receptor Â

... disease in a very small proportion (0.01-0.02%) of HTLV-Iinfected individuals (1) imply that additional genetic changes may be required for the onset of the disease. Nonrandom chromosome translocations are a nearly constant feature of human leukemias and lymphomas. In 1985, we reported re arrangemen ...
On the maintenance of allozyme and inversion polymorphisms in
On the maintenance of allozyme and inversion polymorphisms in

... If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim. Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons ...
in the Budding Yeast, Saccharomyces cer isiae
in the Budding Yeast, Saccharomyces cer isiae

... (Palmer et al., 1989). In these cells, chromosomes migrated as a group within the lumen of the nucleus that extended between the mother cell and bud. This bulk chromosome migration was referred to as nuclear DNA transits. Nuclear DNA transits were observed frequently, were rapid and bidirectional, a ...
Campbell`s Biology: Concepts and Connections, 7e (Reece et al
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6.3 Mendel and Heredity
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lecture 1 File
lecture 1 File

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A selfish origin for recombination

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1: Genetics Worksheet

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Fundamentals of Genetics
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Extrapolation to the whole human genome
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Drosophila rhino Encodes a Female-Specific Chromo
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... but five distinct chromosome arms are still visible in the nurse cells. Prior to degeneration, several consecutive S5 egg chambers are present within each ovariole, leading to the name string of pearls (Cramton and Laski 1994). sop encodes a ribosomal protein, but how this gene product affects chrom ...
The entrapment and characterization of single spermatozoa in a
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Families of SMA - Children with Spinal Muscular Atrophy

... Because each cell contains two of each kind of chromosome, each cell contains two copies of all the human genes, except the genes on the X and Y chromosomes in males There are ~25,000 human genes ...
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Characterisation of interstitial duplications and triplications of

... showed that, in all cases, the duplications and triplications involved the PWACR and were not pseudogene expansions. Retrospective cytogenetic analysis in families 7 and 13 did not identify these duplications clearly. The size of the pericentromeric area of 15q varies greatly within the normal popul ...
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Genetics of Male Infertility - the Infertility Center of St. Louis
Genetics of Male Infertility - the Infertility Center of St. Louis

... and elsewhere, but the repetitive nucleotide sequences which characterize much of the Y chromosome made it very difficult with standard STS markers to define smaller deletions (104). The unusually repetitive sequence structure of the AZFc region of the Y plagued even the first attempts at constructi ...
Wood - 2010 - Nat Rev Genet
Wood - 2010 - Nat Rev Genet

... associate with the nucleolus. Condensin binds all yeast tDNA genes24,25, and disruption of any condensin subunit causes the dispersal of tDNA clusters and infrequent association with the nucleolus. Chemical inhibition of RNAPIII transcription has little effect on condensin binding to tDNA loci, show ...
Teacher Guide - Science Take-Out
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... collected during autopsies. Supplies of this “cadaver” growth hormone were so limited and so expensive that only a few children could be treated. Some of the “cadaver” growth hormone was contaminated with pathogens that caused brain damage. ...
The β-Globin LCR is Not Necessary for an Open Chromatin
The β-Globin LCR is Not Necessary for an Open Chromatin

... Hispanic thalassemia removes ~35 kb of DNA upstream resulting in failure to activate the β-globin locus at the level of transcription All five HSs form when chromosome 11 is transferred to an erythroid environment 5’HSs increase expression of β-globin genes in transfection and transgenic analyses Al ...
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Chromosome



A chromosome (chromo- + -some) is a packaged and organized structure containing most of the DNA of a living organism. It is not usually found on its own, but rather is complexed with many structural proteins called histones as well as associated transcription (copying of genetic sequences) factors and several other macromolecules. Two ""sister"" chromatids (half a chromosome) join together at a protein junction called a centromere. Chromosomes are normally visible under a light microscope only when the cell is undergoing mitosis. Even then, the full chromosome containing both joined sister chromatids becomes visible only during a sequence of mitosis known as metaphase (when chromosomes align together, attached to the mitotic spindle and prepare to divide). This DNA and its associated proteins and macromolecules is collectively known as chromatin, which is further packaged along with its associated molecules into a discrete structure called a nucleosome. Chromatin is present in most cells, with a few exceptions - erythrocytes for example. Occurring only in the nucleus of eukaryotic cells, chromatin composes the vast majority of all DNA, except for a small amount inherited maternally which is found in mitochondria. In prokaryotic cells, chromatin occurs free-floating in cytoplasm, as these cells lack organelles and a defined nucleus. The main information-carrying macromolecule is a single piece of coiled double-stranded DNA, containing many genes, regulatory elements and other noncoding DNA. The DNA-bound macromolecules are proteins, which serve to package the DNA and control its functions. Chromosomes vary widely between different organisms. Some species such as certain bacteria also contain plasmids or other extrachromosomal DNA. These are circular structures in the cytoplasm which contain cellular DNA and play a role in horizontal gene transfer.Compaction of the duplicated chromosomes during cell division (mitosis or meiosis) results either in a four-arm structure (pictured to the right) if the centromere is located in the middle of the chromosome or a two-arm structure if the centromere is located near one of the ends. Chromosomal recombination during meiosis and subsequent sexual reproduction plays a vital role in genetic diversity. If these structures are manipulated incorrectly, through processes known as chromosomal instability and translocation, the cell may undergo mitotic catastrophe and die, or it may unexpectedly evade apoptosis leading to the progression of cancer.In prokaryotes (see nucleoids) and viruses, the DNA is often densely packed and organized. In the case of archaea by homologs to eukaryotic histones, in the case of bacteria by histone-like proteins. Small circular genomes called plasmids are often found in bacteria and also in mitochondria and chloroplasts, reflecting their bacterial origins.
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