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Telomeres: The Aglets of the Genomic World
Telomeres: The Aglets of the Genomic World

... DNA strand, leading to a slightly shorter copied fragment (for the science buffs reading this article, this occurs at the 5’ end of the lagging strand). Damage from molecules known as free radicals also reduces the ends of the DNA in chromosomes. As a result, the copied strand is about 50-200 nucleo ...
Biology Final Exam Review
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7.014 Problem Set 6 Solutions
7.014 Problem Set 6 Solutions

... homologues carrying that gene. Mendel’s First Law – Law of Segregation - In genetics, the separation of alleles, or of homologous chromosomes, from one another during meiosis so that each of the haploid daughter nuclei produced by meiosis contains one or the other member of the pair found in the dip ...
Chapter 11:
Chapter 11:

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The Chromosome Theory of Inheritance
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Ch. 12 DNA - Fort Bend ISD
Ch. 12 DNA - Fort Bend ISD

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vant 1937, dobzhansky
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Lecture Note Objectives: Cells Textbook: Chapter 3 Cells and
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Lecture Title
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... GENERATE NEW GENES For example, crossover 1 (00010) and 4 (10000) at position 1 yields 00000 which evaluates 0! Other results are: 4+5@4 = 10001 (eval: 2) 9+7@3 = 10011 (eval: 3) 8+6@1 = 11011 (eval: 4) 7+5@1 = 01011 (eval: 3) New population evaluation average: 2.4 Since 8 + 6 produces a feasible so ...
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7.27 Spring 2006 PROBLEM SET DUE MAY 12, 2006 1. A couple
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Mutations

... SO! Polyploidy may be more frequent in plants because they are monoecious more often than animals; especially vertebrates. The only case of polyploidy in animals is usually where triploid females survive and reproduce asexually. Over 50% of all flowering plants are polyploid species; many having ari ...
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Chromosome



A chromosome (chromo- + -some) is a packaged and organized structure containing most of the DNA of a living organism. It is not usually found on its own, but rather is complexed with many structural proteins called histones as well as associated transcription (copying of genetic sequences) factors and several other macromolecules. Two ""sister"" chromatids (half a chromosome) join together at a protein junction called a centromere. Chromosomes are normally visible under a light microscope only when the cell is undergoing mitosis. Even then, the full chromosome containing both joined sister chromatids becomes visible only during a sequence of mitosis known as metaphase (when chromosomes align together, attached to the mitotic spindle and prepare to divide). This DNA and its associated proteins and macromolecules is collectively known as chromatin, which is further packaged along with its associated molecules into a discrete structure called a nucleosome. Chromatin is present in most cells, with a few exceptions - erythrocytes for example. Occurring only in the nucleus of eukaryotic cells, chromatin composes the vast majority of all DNA, except for a small amount inherited maternally which is found in mitochondria. In prokaryotic cells, chromatin occurs free-floating in cytoplasm, as these cells lack organelles and a defined nucleus. The main information-carrying macromolecule is a single piece of coiled double-stranded DNA, containing many genes, regulatory elements and other noncoding DNA. The DNA-bound macromolecules are proteins, which serve to package the DNA and control its functions. Chromosomes vary widely between different organisms. Some species such as certain bacteria also contain plasmids or other extrachromosomal DNA. These are circular structures in the cytoplasm which contain cellular DNA and play a role in horizontal gene transfer.Compaction of the duplicated chromosomes during cell division (mitosis or meiosis) results either in a four-arm structure (pictured to the right) if the centromere is located in the middle of the chromosome or a two-arm structure if the centromere is located near one of the ends. Chromosomal recombination during meiosis and subsequent sexual reproduction plays a vital role in genetic diversity. If these structures are manipulated incorrectly, through processes known as chromosomal instability and translocation, the cell may undergo mitotic catastrophe and die, or it may unexpectedly evade apoptosis leading to the progression of cancer.In prokaryotes (see nucleoids) and viruses, the DNA is often densely packed and organized. In the case of archaea by homologs to eukaryotic histones, in the case of bacteria by histone-like proteins. Small circular genomes called plasmids are often found in bacteria and also in mitochondria and chloroplasts, reflecting their bacterial origins.
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