Figure S2 - Development
... bozozok acts as a strong bicoid antimorph in Drosophila Given the similarity of the homeodomain of Boz to that of the Drosophila gene bicoid (bcd), we argue that Boz might be able to bind bcd sites in the Drosophila embryo (indeed, we were able to show that Boz binds Bcd-binding sites, see Fig. 5A). ...
... bozozok acts as a strong bicoid antimorph in Drosophila Given the similarity of the homeodomain of Boz to that of the Drosophila gene bicoid (bcd), we argue that Boz might be able to bind bcd sites in the Drosophila embryo (indeed, we were able to show that Boz binds Bcd-binding sites, see Fig. 5A). ...
Argonaute2 Is Essential for Mammalian
... embryonic germ layers: ectoderm, endoderm, and mesoderm. The gene Brachyury is essential for mesoderm development, and shorttail mice, which were later found to be carrying a Brachyury mutation, have been known since 1927. In this study, we found a genetic interaction between Brachyury and another g ...
... embryonic germ layers: ectoderm, endoderm, and mesoderm. The gene Brachyury is essential for mesoderm development, and shorttail mice, which were later found to be carrying a Brachyury mutation, have been known since 1927. In this study, we found a genetic interaction between Brachyury and another g ...
the kinship theory of genomic imprinting - Fischer Lab
... can be explained by subsidiary hypotheses (sex-linkage, cytoplasmic inheritance, apomixis, maternal effects) that do not challenge the basic hypothesis that the phenotypic expression of a gene is unchanged by the sex of the transmitting parent. The general validity of this hypothesis has been overwh ...
... can be explained by subsidiary hypotheses (sex-linkage, cytoplasmic inheritance, apomixis, maternal effects) that do not challenge the basic hypothesis that the phenotypic expression of a gene is unchanged by the sex of the transmitting parent. The general validity of this hypothesis has been overwh ...
Slide 1
... production of functional sperm. In individuals lacking the SRY gene, the generic embryonic gonads develop into ovaries. ...
... production of functional sperm. In individuals lacking the SRY gene, the generic embryonic gonads develop into ovaries. ...
PDF
... modern vertebrate clusters apparently arose by serial duplication of a 13 member cluster with subsequent deletions. As a result, the homologous genes in different clusters (referred to as paralogues) are more similar to each other than they are to adjacent genes in the same cluster. Paralogous genes ...
... modern vertebrate clusters apparently arose by serial duplication of a 13 member cluster with subsequent deletions. As a result, the homologous genes in different clusters (referred to as paralogues) are more similar to each other than they are to adjacent genes in the same cluster. Paralogous genes ...
Slide 1
... diagram that shows the relationships within a family, is used. In a pedigree, a circle represents a female, and a square represents a male. A filled-in circle or square shows that the individual has the trait being studied. The horizontal line that connects a circle and a square represents a marriag ...
... diagram that shows the relationships within a family, is used. In a pedigree, a circle represents a female, and a square represents a male. A filled-in circle or square shows that the individual has the trait being studied. The horizontal line that connects a circle and a square represents a marriag ...
Review
... particular linkage group (such as a Y or W chromosome) influence the probability of developing as a male or a female. Genetic control of sex need not be complete— in many organisms, environmental conditions, experimental treatments, or the genetic background, can affect the phenotypic sex of individ ...
... particular linkage group (such as a Y or W chromosome) influence the probability of developing as a male or a female. Genetic control of sex need not be complete— in many organisms, environmental conditions, experimental treatments, or the genetic background, can affect the phenotypic sex of individ ...
Lecture 35 – PDF
... inception, either because of effects of chromosome breakage or because of fertility problems in the chromosomal heterozygote (remember there is only a single chromosomal heterozygote in the population at inception). However, the occurrence of both chromosomal polymorphisms within species and chromos ...
... inception, either because of effects of chromosome breakage or because of fertility problems in the chromosomal heterozygote (remember there is only a single chromosomal heterozygote in the population at inception). However, the occurrence of both chromosomal polymorphisms within species and chromos ...
Lgi1 null mutant mice exhibit myoclonic seizures
... RT – PCR analysis of RNA derived from the hippocampus and cortex of null mutant mice, as expected, showed the absence of Lgi1 gene expression compared with wild-type and heterozygous littermates (Fig. 3). To examine temporal expression of Lgi1, we performed RT – PCR analysis on hippocampal mRNA from ...
... RT – PCR analysis of RNA derived from the hippocampus and cortex of null mutant mice, as expected, showed the absence of Lgi1 gene expression compared with wild-type and heterozygous littermates (Fig. 3). To examine temporal expression of Lgi1, we performed RT – PCR analysis on hippocampal mRNA from ...
Transcription factories are nuclear subcompartments that remain in
... Transcription is a fundamental, life-essential process, yet we lack a clear picture of how and where it occurs in vivo. Textbooks tell us that RNA polymerase II (RNAPII) is recruited to the promoters of genes when they become active, suggesting that transcription sites form de novo on individual gen ...
... Transcription is a fundamental, life-essential process, yet we lack a clear picture of how and where it occurs in vivo. Textbooks tell us that RNA polymerase II (RNAPII) is recruited to the promoters of genes when they become active, suggesting that transcription sites form de novo on individual gen ...
S2 File.
... were harvested after 1 day of incubation, while wells with NaCl addition were harvested after 2 days, to ensure that cells in both conditions would be in their exponential growth phase. The pictures underneath the data bars show the corresponding stained biofilms, before extraction with methanol. Re ...
... were harvested after 1 day of incubation, while wells with NaCl addition were harvested after 2 days, to ensure that cells in both conditions would be in their exponential growth phase. The pictures underneath the data bars show the corresponding stained biofilms, before extraction with methanol. Re ...
publication
... the shuffling of exons during protein evolution. Allied with this hypothesis was the notion that exons encoded structural and/or functional domains of proteins. Although several notable examples of the latter have been demonstrated, and indeed the presence of introns in such cases could reasonably m ...
... the shuffling of exons during protein evolution. Allied with this hypothesis was the notion that exons encoded structural and/or functional domains of proteins. Although several notable examples of the latter have been demonstrated, and indeed the presence of introns in such cases could reasonably m ...
Lecture9_10_extra2 - Welcome to people.pharmacy.purdue.edu!
... HLA-DPAP, HLA-DPBP HLA-DQAP, HLA-DQBP HLA-DRAP, HLA-DRBP ...
... HLA-DPAP, HLA-DPBP HLA-DQAP, HLA-DQBP HLA-DRAP, HLA-DRBP ...
Powerpoint template for scientific posters (Swarthmore College)
... manipulation of runt activity in all cells of the blastoderm stage Drosophila embryo. Central to this work is the observation that the engrailed expression correlates with embryo lethality. If the females used to generate these embryos had reduced dosage of a factor that worked with runt to repress ...
... manipulation of runt activity in all cells of the blastoderm stage Drosophila embryo. Central to this work is the observation that the engrailed expression correlates with embryo lethality. If the females used to generate these embryos had reduced dosage of a factor that worked with runt to repress ...
Medical Genetics
... derived from intracellular proteins are generated by proteolytic degradation by a large multifunctional protease (LMP); the peptides are then transported to the cell surface and held in a cleft formed in the class I molecule to display the peptide antigen to cytotoxic T cells. ...
... derived from intracellular proteins are generated by proteolytic degradation by a large multifunctional protease (LMP); the peptides are then transported to the cell surface and held in a cleft formed in the class I molecule to display the peptide antigen to cytotoxic T cells. ...
Monoallelic Expression and Dominance
... which SCRa was “silent” showed that SCRa was expressed in SaSa progeny and “silenced” in their SaSb sibs. Thus, the low-expression state of SCRa is not heritable and is probably not due to an unlinked modifier gene influencing SCRa transcription or the stability of its transcripts. Why is expression ...
... which SCRa was “silent” showed that SCRa was expressed in SaSa progeny and “silenced” in their SaSb sibs. Thus, the low-expression state of SCRa is not heritable and is probably not due to an unlinked modifier gene influencing SCRa transcription or the stability of its transcripts. Why is expression ...
Ch.14 - Study Guide
... Explain how observations by Mendel and others and Mendel's hypothesis of inheritance differed from the blending theory of inheritance. List several features of Mendel's methods that contributed to his success. Define true breeding, hybridization, monohybrid cross, P generation, F 1 generation, and F ...
... Explain how observations by Mendel and others and Mendel's hypothesis of inheritance differed from the blending theory of inheritance. List several features of Mendel's methods that contributed to his success. Define true breeding, hybridization, monohybrid cross, P generation, F 1 generation, and F ...
Integration of the Classical and Molecular Linkage Maps of Tomato
... the species L. esculentum and mapped using intraspecific crosses. As the number of DNA polymorphisms detectable between genotypes of L. esculentum is very 1990; VAN DER BEEKet low (MILLERand TANKSLEY al. 1992), construction of an integrated mapof an entire chromosome is only attainable through linka ...
... the species L. esculentum and mapped using intraspecific crosses. As the number of DNA polymorphisms detectable between genotypes of L. esculentum is very 1990; VAN DER BEEKet low (MILLERand TANKSLEY al. 1992), construction of an integrated mapof an entire chromosome is only attainable through linka ...
! Mendel`s Law of Independent Assortment
... these patterns, to a single child. (If there are more children, they are placed off a horizontal line.) Which pattern of inheritance (I or II) do you suppose represents an autosomal dominant characteristic, and which represents an autosomal recessive characteristic? In pattern I, the child is affect ...
... these patterns, to a single child. (If there are more children, they are placed off a horizontal line.) Which pattern of inheritance (I or II) do you suppose represents an autosomal dominant characteristic, and which represents an autosomal recessive characteristic? In pattern I, the child is affect ...
The silence of genes
... he first molecular evidence for imprinting in mammals came in the mid-1980s, when two studies showed that functional differences between maternal and paternal gametes are carried through to the embryo and survive activation of the embryonic genome in the twocell phase (McGrath & Solter, 1985; Surani ...
... he first molecular evidence for imprinting in mammals came in the mid-1980s, when two studies showed that functional differences between maternal and paternal gametes are carried through to the embryo and survive activation of the embryonic genome in the twocell phase (McGrath & Solter, 1985; Surani ...
Principles of Inheritance: Mendel`s Laws and Genetic
... pods or green pods); underlying the experiments was the implicit assumption that there were two genetic variants, say A and a, one for each of the two forms of each trait. The use of pure parental forms assured that the experiments always started with the mating of two homozygous parents, either AA ...
... pods or green pods); underlying the experiments was the implicit assumption that there were two genetic variants, say A and a, one for each of the two forms of each trait. The use of pure parental forms assured that the experiments always started with the mating of two homozygous parents, either AA ...
Hemolytic anemias - Hemoglobinopathies
... overload; Gene therapy? – +2, or 3 homozygous = thalassemia intermedia – Heterozygosity of 0, or + = thalassemia minor » Mild hypochromic, microcytic anemia » Patients are usually asymptomatic with symptoms occurring under stressful conditions such as pregnancy – thalassemia may also be found ...
... overload; Gene therapy? – +2, or 3 homozygous = thalassemia intermedia – Heterozygosity of 0, or + = thalassemia minor » Mild hypochromic, microcytic anemia » Patients are usually asymptomatic with symptoms occurring under stressful conditions such as pregnancy – thalassemia may also be found ...
Nitrogen fixation:
... Acetobacter species (Caballero-Mellado et al., 1999; Fuentes-Ramírez et al, this volume) or Paenibacillus among aerobic endospore-forming Firmicutes (Achouak et al., 1999). In Archea, Nfixation is a general property of the methanogen group and nif genes are found in halophiles, but no fixers have be ...
... Acetobacter species (Caballero-Mellado et al., 1999; Fuentes-Ramírez et al, this volume) or Paenibacillus among aerobic endospore-forming Firmicutes (Achouak et al., 1999). In Archea, Nfixation is a general property of the methanogen group and nif genes are found in halophiles, but no fixers have be ...
Effective Gene Selection Method Using Bayesian Discriminant
... the maximal generation reaches. (a) (Selection) the fitter chromosomes are selected from the N individuals in the population for evolution. The fitness of a chromosome C is defined as fitness (C) = BD(XC),the selection of the fitter chromosomes is based on the fitness value. (b) (Crossover) choose o ...
... the maximal generation reaches. (a) (Selection) the fitter chromosomes are selected from the N individuals in the population for evolution. The fitness of a chromosome C is defined as fitness (C) = BD(XC),the selection of the fitter chromosomes is based on the fitness value. (b) (Crossover) choose o ...
X-inactivation
X-inactivation (also called lyonization) is a process by which one of the two copies of the X chromosome present in female mammals is inactivated. The inactive X chromosome is silenced by its being packaged in such a way that it has a transcriptionally inactive structure called heterochromatin. As nearly all female mammals have two X chromosomes, X-inactivation prevents them from having twice as many X chromosome gene products as males, who only possess a single copy of the X chromosome (see dosage compensation). The choice of which X chromosome will be inactivated is random in placental mammals such as humans, but once an X chromosome is inactivated it will remain inactive throughout the lifetime of the cell and its descendants in the organism. Unlike the random X-inactivation in placental mammals, inactivation in marsupials applies exclusively to the paternally derived X chromosome.