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Comparison of the separation of Candida albicans chromosome
Comparison of the separation of Candida albicans chromosome

... To test if bands F/G and E/H of Figure 3 were doublets, we attempted to separate by FIGE the chromosome components in the doublets by increasing the switching interval from 100 seconds forward and 25 seconds backwards to 125 seconds forward and 31.3 seconds backwards. Six ethidium bromide staining b ...
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... too many. The body will adjust to this extra chromosome by randomly switching one X chromosome off when it is not in need.  These switched off X chromosomes will form a dense region in the nucleus known as a Barr Body. These are generally only found in females since males need the one X chromosome ...
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X-inactivation



X-inactivation (also called lyonization) is a process by which one of the two copies of the X chromosome present in female mammals is inactivated. The inactive X chromosome is silenced by its being packaged in such a way that it has a transcriptionally inactive structure called heterochromatin. As nearly all female mammals have two X chromosomes, X-inactivation prevents them from having twice as many X chromosome gene products as males, who only possess a single copy of the X chromosome (see dosage compensation). The choice of which X chromosome will be inactivated is random in placental mammals such as humans, but once an X chromosome is inactivated it will remain inactive throughout the lifetime of the cell and its descendants in the organism. Unlike the random X-inactivation in placental mammals, inactivation in marsupials applies exclusively to the paternally derived X chromosome.
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