Algorithms for Finding Gene Clusters
... Genomes of higher organisms generally consist of several linear chromosomes while bacterial, archaeal, and mitochondrial DNA is organized in one to several circular pieces. While in the first case the algorithm from [10] might report too many gene clusters if the multiple chromosomes are simply conc ...
... Genomes of higher organisms generally consist of several linear chromosomes while bacterial, archaeal, and mitochondrial DNA is organized in one to several circular pieces. While in the first case the algorithm from [10] might report too many gene clusters if the multiple chromosomes are simply conc ...
- LSHTM Research Online
... a tier 1 select agent and potential bioterrorism threat by the U.S. Centers for Disease Control and Prevention. There is no licensed vaccine available to prevent melioidosis, and because B. pseudomallei demonstrates extraordinary resistance to many antibiot- ...
... a tier 1 select agent and potential bioterrorism threat by the U.S. Centers for Disease Control and Prevention. There is no licensed vaccine available to prevent melioidosis, and because B. pseudomallei demonstrates extraordinary resistance to many antibiot- ...
Gene Section (Drosophila). Atlas of Genetics and Cytogenetics
... line PEER using three RP11 library clones located immediately centromeric (779o18, labelled red), spanning (466h21, green) and telomeric (45g21, yellow) of NKX2-5. (See below for map.) The rearrangement may be a simple insertion or, a double translocation whereby chromosome 14 material is first tran ...
... line PEER using three RP11 library clones located immediately centromeric (779o18, labelled red), spanning (466h21, green) and telomeric (45g21, yellow) of NKX2-5. (See below for map.) The rearrangement may be a simple insertion or, a double translocation whereby chromosome 14 material is first tran ...
Genetic Inversion: Relationships Among Species
... for black fur then it causes the animal to have white fur thus blending better with its environment. Disadvantageous – same as above but either the environment was different so the color change was not preferred or the inactivated gene coded for a protein that is essential for the survival of the or ...
... for black fur then it causes the animal to have white fur thus blending better with its environment. Disadvantageous – same as above but either the environment was different so the color change was not preferred or the inactivated gene coded for a protein that is essential for the survival of the or ...
VI. The relationship between genotype and phenotype is rarely simple
... – a ratio of 3:1. The inheritable factor for white flowers was not lost, so the hypothesis was rejected. Conclusions: From these types of experiments and observations, Mendel concluded that since the inheritable factor for white flowers was not lost in the F1 generation, it must have been masked by ...
... – a ratio of 3:1. The inheritable factor for white flowers was not lost, so the hypothesis was rejected. Conclusions: From these types of experiments and observations, Mendel concluded that since the inheritable factor for white flowers was not lost in the F1 generation, it must have been masked by ...
pdf - University of Pennsylvania
... In the early embryo, the hybrid nos-tub3′UTR RNA, which bears α-tubulin 3′UTR sequences in place of the nos 3′UTR, is not subject to TCE-mediated regulation and is consequently translated throughout the early embryo (Gavis and Lehmann, 1994). By contrast, nos-tub:nos+2 RNA, which contains an inserti ...
... In the early embryo, the hybrid nos-tub3′UTR RNA, which bears α-tubulin 3′UTR sequences in place of the nos 3′UTR, is not subject to TCE-mediated regulation and is consequently translated throughout the early embryo (Gavis and Lehmann, 1994). By contrast, nos-tub:nos+2 RNA, which contains an inserti ...
Teacher Guide: Gene Expression. By Ann Brokaw.
... From the Author With the pace of current research, the biological sciences change incredibly fast, particularly in the fields of molecular genetics, specifically gene expression. Therefore, as a veteran biology teacher, I am constantly looking for resources that include up-to-date research, prompt ...
... From the Author With the pace of current research, the biological sciences change incredibly fast, particularly in the fields of molecular genetics, specifically gene expression. Therefore, as a veteran biology teacher, I am constantly looking for resources that include up-to-date research, prompt ...
Functional significance of the discordance between
... in freshly isolated cardiac myocytes, as well as LV developed pressure (LVDP), LV +dP/dt and LV –dP/dt in isolated buffer–perfused Langendorff hearts. As shown by the representative sarcomere shortening curves in Figure 2A and group data shown in Figure 2B, there was a significant decrease (P < 0.05 ...
... in freshly isolated cardiac myocytes, as well as LV developed pressure (LVDP), LV +dP/dt and LV –dP/dt in isolated buffer–perfused Langendorff hearts. As shown by the representative sarcomere shortening curves in Figure 2A and group data shown in Figure 2B, there was a significant decrease (P < 0.05 ...
Genome Evolution Due to Allopolyploidization in Wheat
... et al. 2002), still share a high degree of gene synteny and DNA sequence homology. However, they differ from one another by a number of noncoding and highly repetitious DNA sequences (Flavell 1982), and many functional gene complexes (Wicker et al. 2011 and references therein). In spite of this gene ...
... et al. 2002), still share a high degree of gene synteny and DNA sequence homology. However, they differ from one another by a number of noncoding and highly repetitious DNA sequences (Flavell 1982), and many functional gene complexes (Wicker et al. 2011 and references therein). In spite of this gene ...
Efficient Ends-Out Gene Targeting In Drosophila
... the transmembrane domain of Crumbs, we first made a pUAST-Crumbs-intra::mEosFP construct. In brief, a gDNA of 840bp encoding the transmembrane domain, the intracellular domain and the 3'UTR of crumbs up to the XbaI site (W ODARZ et al. 1995) was PCR amplified from gDNA by YH633 and YH634, with the o ...
... the transmembrane domain of Crumbs, we first made a pUAST-Crumbs-intra::mEosFP construct. In brief, a gDNA of 840bp encoding the transmembrane domain, the intracellular domain and the 3'UTR of crumbs up to the XbaI site (W ODARZ et al. 1995) was PCR amplified from gDNA by YH633 and YH634, with the o ...
Off-target Effects: Disturbing the Silence of RNA
... generated by off-target effects represents a prominent roadblock to RNAi technologies in research, therapeutic, and diagnostic settings. As described above, pooling strategies, chemical modifications, and novel rational design filters can significantly reduce off-targets without jeopardizing on-targ ...
... generated by off-target effects represents a prominent roadblock to RNAi technologies in research, therapeutic, and diagnostic settings. As described above, pooling strategies, chemical modifications, and novel rational design filters can significantly reduce off-targets without jeopardizing on-targ ...
HED - National Foundation for Ectodermal Dysplasias
... A correct diagnosis is necessary for prognosis. To anticipate what kinds of problems an individual with ED may have or to reduce concern about what problems may or, indeed may not arise, doctors must know the natural history of the specific condition. A correct diagnosis is also important to predict ...
... A correct diagnosis is necessary for prognosis. To anticipate what kinds of problems an individual with ED may have or to reduce concern about what problems may or, indeed may not arise, doctors must know the natural history of the specific condition. A correct diagnosis is also important to predict ...
genes - McGraw Hill Higher Education
... Heterozygosity for deletions may have phenotypic consequences With some genes, an abnormal phenotype can be caused by an imbalance in gene dosage (i.e. 2 copies vs. 1 copy of an autosomal gene) In humans, deletion heterozygotes with loss of >3% of genome are not viable Fig. 13.3 Copyright © The McG ...
... Heterozygosity for deletions may have phenotypic consequences With some genes, an abnormal phenotype can be caused by an imbalance in gene dosage (i.e. 2 copies vs. 1 copy of an autosomal gene) In humans, deletion heterozygotes with loss of >3% of genome are not viable Fig. 13.3 Copyright © The McG ...
Lab #2
... • Over-representation analysis (ORA) detects surprising enrichment of gene annotations in a gene list. • Fisher’s exact test is used for ORA of gene lists for a single type of annotation, • P-value for Fisher’s exact test – is “the probability that a random draw of the same size as the gene list fro ...
... • Over-representation analysis (ORA) detects surprising enrichment of gene annotations in a gene list. • Fisher’s exact test is used for ORA of gene lists for a single type of annotation, • P-value for Fisher’s exact test – is “the probability that a random draw of the same size as the gene list fro ...
- Lab Fabiana Perocchi
... probe offset of 8 bp and a 4-bp shift between the two strands. The array also contains probes (red) complementary to the YJM789 sequence for polymorphic regions, as shown here for a SNP marked by an asterisk. (B) Modeling the hybridization intensity. Consider a two-allelic transcript with two indels ...
... probe offset of 8 bp and a 4-bp shift between the two strands. The array also contains probes (red) complementary to the YJM789 sequence for polymorphic regions, as shown here for a SNP marked by an asterisk. (B) Modeling the hybridization intensity. Consider a two-allelic transcript with two indels ...
Chapter 14: MENDEL AND THE GENE IDEA
... organism of unknown genotype with a homozygous recessive individual to determine the unknown genotype. The ratio of phenotypes in the offspring reveals the unknown genotype. Results: Matching the results to either prediction identifies the unknown parental genotype (either PP or Pp in this example). ...
... organism of unknown genotype with a homozygous recessive individual to determine the unknown genotype. The ratio of phenotypes in the offspring reveals the unknown genotype. Results: Matching the results to either prediction identifies the unknown parental genotype (either PP or Pp in this example). ...
Genetic Polymorphism and SNPs - McGill School Of Computer
... the number of base differences between two genomes over the number of bases compared. This is approximately 1/1000 (1/1350) base pairs between two equivalent chromosomes. Distribution of SNPs SNPs are not uniformly distributed over the entire human genome, neither over all chromosomes and neither wi ...
... the number of base differences between two genomes over the number of bases compared. This is approximately 1/1000 (1/1350) base pairs between two equivalent chromosomes. Distribution of SNPs SNPs are not uniformly distributed over the entire human genome, neither over all chromosomes and neither wi ...
Hailey Spelman - Determining Cellular Fate: Pre- and Postnatal Methylation Effects on Gene Expression
... off genes that are functional and thus contribute to the final phenotype. Examples of the effect of simple measures on methylation patterns during prenatal development are clear in their ability to change phenotypic expression. Based on this idea, if scientists could target methylation of specific g ...
... off genes that are functional and thus contribute to the final phenotype. Examples of the effect of simple measures on methylation patterns during prenatal development are clear in their ability to change phenotypic expression. Based on this idea, if scientists could target methylation of specific g ...
20. Transposable Genetic Elements
... Here C allows color expression and Ds+ and Ac+ indicate the lack of the element. Most of the kernels from this cross were of the expected types (Figure 20-4), but one exceptional kernel was very interesting. In Figure 20-4, the first seed shows the normal solid pigment pattern owing to the presence ...
... Here C allows color expression and Ds+ and Ac+ indicate the lack of the element. Most of the kernels from this cross were of the expected types (Figure 20-4), but one exceptional kernel was very interesting. In Figure 20-4, the first seed shows the normal solid pigment pattern owing to the presence ...
Answer key and markscheme
... The markschemes have been developed independently by the publisher and the content is in no way connected with nor endorsed by the International Baccalaureate Organization. ...
... The markschemes have been developed independently by the publisher and the content is in no way connected with nor endorsed by the International Baccalaureate Organization. ...
Networks in leaf development
... Leaf patterning can be altered by the ectopic expression of class I KNOX genes (reviewed in [3,34]). Typically, these genes are expressed in the SAM and downregulated in leaf primordia. The myb domain transcription factors PHANTASTICA (PHAN) in Antirrhinum, rough sheath2 (rs2) in maize and ASYMMETRI ...
... Leaf patterning can be altered by the ectopic expression of class I KNOX genes (reviewed in [3,34]). Typically, these genes are expressed in the SAM and downregulated in leaf primordia. The myb domain transcription factors PHANTASTICA (PHAN) in Antirrhinum, rough sheath2 (rs2) in maize and ASYMMETRI ...
The role of Dby mRNA in early development of male mouse zygotes
... Ejaculated mammalian spermatozoa contain a complex yet specific population of mRNA. However, the possible roles that mRNA has in early zygotic and embryonic development remain unclear. We found that Dby mRNA is selectively retained in capacitated mouse spermatozoa, and is transferred into the oocyte ...
... Ejaculated mammalian spermatozoa contain a complex yet specific population of mRNA. However, the possible roles that mRNA has in early zygotic and embryonic development remain unclear. We found that Dby mRNA is selectively retained in capacitated mouse spermatozoa, and is transferred into the oocyte ...
peas? - Westgate Mennonite Collegiate
... Public Domain — Where the work or any of its elements is in the public domain under applicable law, that status is in no way affected by the license. Other Rights — In no way are any of the following rights affected by the license: Your fair dealing or fair use rights, or other applicable copyright ...
... Public Domain — Where the work or any of its elements is in the public domain under applicable law, that status is in no way affected by the license. Other Rights — In no way are any of the following rights affected by the license: Your fair dealing or fair use rights, or other applicable copyright ...
Pea Taste Slides - Evo-Ed
... Public Domain — Where the work or any of its elements is in the public domain under applicable law, that status is in no way affected by the license. Other Rights — In no way are any of the following rights affected by the license: Your fair dealing or fair use rights, or other applicable copyright ...
... Public Domain — Where the work or any of its elements is in the public domain under applicable law, that status is in no way affected by the license. Other Rights — In no way are any of the following rights affected by the license: Your fair dealing or fair use rights, or other applicable copyright ...
X-inactivation
X-inactivation (also called lyonization) is a process by which one of the two copies of the X chromosome present in female mammals is inactivated. The inactive X chromosome is silenced by its being packaged in such a way that it has a transcriptionally inactive structure called heterochromatin. As nearly all female mammals have two X chromosomes, X-inactivation prevents them from having twice as many X chromosome gene products as males, who only possess a single copy of the X chromosome (see dosage compensation). The choice of which X chromosome will be inactivated is random in placental mammals such as humans, but once an X chromosome is inactivated it will remain inactive throughout the lifetime of the cell and its descendants in the organism. Unlike the random X-inactivation in placental mammals, inactivation in marsupials applies exclusively to the paternally derived X chromosome.