Precise long non-coding RNA modulation in visual maintenance
... regional variation in the thickness of the photoreceptor layer and may secondarily damage the thickness of the adjacent inner nuclear layer. lncRNA TUG1 was expressed in the developing and adult retinal tissues to promote the production of rod photoreceptors. In the newborn retina, knockdown of TUG1 ...
... regional variation in the thickness of the photoreceptor layer and may secondarily damage the thickness of the adjacent inner nuclear layer. lncRNA TUG1 was expressed in the developing and adult retinal tissues to promote the production of rod photoreceptors. In the newborn retina, knockdown of TUG1 ...
Assessment of Alleged Retinal Laser Injuries
... stabilize within a few months. These findings are consistent, stable, and well correlated with retinal findings in cooperative patients. Momentary pain may occur at the time of ocular laser injury, but only rarely. This pain does not persist, just as it does not persist after clinical retinal photoc ...
... stabilize within a few months. These findings are consistent, stable, and well correlated with retinal findings in cooperative patients. Momentary pain may occur at the time of ocular laser injury, but only rarely. This pain does not persist, just as it does not persist after clinical retinal photoc ...
Ophthalmology - University of Virginia Health System
... appropriate “unspecified” code (e.g., a diagnosis of pneumonia has been determined, but not the specific type). In fact, unspecified codes should be reported when they are the codes that most accurately reflects what is known about the patient’s condition at the time of that particular encounter. It ...
... appropriate “unspecified” code (e.g., a diagnosis of pneumonia has been determined, but not the specific type). In fact, unspecified codes should be reported when they are the codes that most accurately reflects what is known about the patient’s condition at the time of that particular encounter. It ...
PDF
... controlling eye growth in the chick embryo (Coulombre, 1956). In order to test this suggestion we studied (1) the pattern of eye growth throughout life in rats; (2) the characteristics of the cycling RPE cells during thefirst2 weeks after birth (the period found to be critical for postnatal RPE diff ...
... controlling eye growth in the chick embryo (Coulombre, 1956). In order to test this suggestion we studied (1) the pattern of eye growth throughout life in rats; (2) the characteristics of the cycling RPE cells during thefirst2 weeks after birth (the period found to be critical for postnatal RPE diff ...
Compound developmental eye disorders following inactivation of
... in transgenic mice allows monitoring of NC-cell migration and fate during development in vivo [9,14]. This approach was used in the present study to define the ocular structures originating from the NC. Rosa26 Cre reporter (Rosa26R) mice, which express -galactosidase following Cre-mediated recombin ...
... in transgenic mice allows monitoring of NC-cell migration and fate during development in vivo [9,14]. This approach was used in the present study to define the ocular structures originating from the NC. Rosa26 Cre reporter (Rosa26R) mice, which express -galactosidase following Cre-mediated recombin ...
Acquired Maculopathy
... a gas bubble into the eye and place the patient face down in order to tamponade the hemorrhage and spread the blood out. There is no great treatment for a subfoveal CNVM. Some surgeons are lasering subfoveal membranes in the thought that the laser damage will be less severe than the natural course o ...
... a gas bubble into the eye and place the patient face down in order to tamponade the hemorrhage and spread the blood out. There is no great treatment for a subfoveal CNVM. Some surgeons are lasering subfoveal membranes in the thought that the laser damage will be less severe than the natural course o ...
Hutson and Chien_2002 - Marine Biological Laboratory
... visualize encounters between Mauthner axons and their motor neuron targets. They showed that the presynaptic axon does not always play an active role; instead, synapses sometimes form after dendritic filopodia from the postsynaptic motor neuron reach out to contact a passing Mauthner axon. Ono et al ...
... visualize encounters between Mauthner axons and their motor neuron targets. They showed that the presynaptic axon does not always play an active role; instead, synapses sometimes form after dendritic filopodia from the postsynaptic motor neuron reach out to contact a passing Mauthner axon. Ono et al ...
NUTRITIONAL THERAPIES in Preventing Macular Degeneration
... VEGF signaling.74 Long-chain omega3s are highly susceptible to oxidative damage; one of the key roles of retinal xanthophyll carotenoids, present in high concentrations in photoreceptor outer segments, may be to preserve the native structure of DHA in these photoreceptors.60 In foods and in suppleme ...
... VEGF signaling.74 Long-chain omega3s are highly susceptible to oxidative damage; one of the key roles of retinal xanthophyll carotenoids, present in high concentrations in photoreceptor outer segments, may be to preserve the native structure of DHA in these photoreceptors.60 In foods and in suppleme ...
The Acute Red Eye and Ocular Trauma
... World Health Organisation. Visual Impairment and Blindness. June 2012. Available from http://www.who.int/mediacentre/factsheets/fs282/en/ ...
... World Health Organisation. Visual Impairment and Blindness. June 2012. Available from http://www.who.int/mediacentre/factsheets/fs282/en/ ...
CONTROL OF CELL NUMBER IN THE DEVELOPING MAMMALIAN
... from thalamus to cortex have been studied particularly well in cats and monkeys (Sanderson, 1971; Mcllwain, 1975; Wilson and Sherman, 1976; Peichl and Wassle, 1979; Connolly and Van Essen, 1984; Schein and de Monasterio, 1987). Central to this discussion is the fact that functional "streams" (Van Es ...
... from thalamus to cortex have been studied particularly well in cats and monkeys (Sanderson, 1971; Mcllwain, 1975; Wilson and Sherman, 1976; Peichl and Wassle, 1979; Connolly and Van Essen, 1984; Schein and de Monasterio, 1987). Central to this discussion is the fact that functional "streams" (Van Es ...
Angiotensin-converting enzyme activity in ocular fluids.
... than aqueous humor. Enzyme activity was determined fluorimetrically from the rate of breakdown of the substrate, hippuryl-L-histidyl-L-leucine. The enzyme activity was further characterized by determining the effects of inhibitors. There was a significant difference in ACE levels in human tears when ...
... than aqueous humor. Enzyme activity was determined fluorimetrically from the rate of breakdown of the substrate, hippuryl-L-histidyl-L-leucine. The enzyme activity was further characterized by determining the effects of inhibitors. There was a significant difference in ACE levels in human tears when ...
Session 239 Embryology and morphogenesis of ocular
... Molecular Biology, University of Texas at Austin, Austin, TX. Purpose: Mutations in MAB21L2 result in colobomas and associated eye defects. The molecular and cellular underpinnings of these defects are unknown, and the normal cellular function of MAB21L2 is likewise enigmatic given that it possesses ...
... Molecular Biology, University of Texas at Austin, Austin, TX. Purpose: Mutations in MAB21L2 result in colobomas and associated eye defects. The molecular and cellular underpinnings of these defects are unknown, and the normal cellular function of MAB21L2 is likewise enigmatic given that it possesses ...
Progress in Measurement of Ocular Blood Flow and Age-Related Macular Degeneration
... perfusion defects in many disorders, including glaucoma and age-related macular degeneration, two of the most prevalent causes of blindness in the industrialized world. Recently it has become clear, in animal models of glaucoma, that retinal ganglion cells die via apoptosis. The factors that initiat ...
... perfusion defects in many disorders, including glaucoma and age-related macular degeneration, two of the most prevalent causes of blindness in the industrialized world. Recently it has become clear, in animal models of glaucoma, that retinal ganglion cells die via apoptosis. The factors that initiat ...
- The University of Liverpool Repository
... poor solubility of many drugs within silicone oil or the inability to control release rates. The opportunity has significant clinical relevance as the ability to control the release of antiproliferative drugs and/or anti-inflammatory agents to the posterior of the eye would present options to consid ...
... poor solubility of many drugs within silicone oil or the inability to control release rates. The opportunity has significant clinical relevance as the ability to control the release of antiproliferative drugs and/or anti-inflammatory agents to the posterior of the eye would present options to consid ...
Nonproliferative retinopathy in diabetes type 2. Initial
... of NPDR could not be examined’’ (Early Treatment Diabetic Retinopathy Study Research Group, 1991). For example, it could not determine whether presence of mild retinal hemorrhages in addition to microaneurysms was sufficiently less severe than the presence of hard or soft exudates to merit designatio ...
... of NPDR could not be examined’’ (Early Treatment Diabetic Retinopathy Study Research Group, 1991). For example, it could not determine whether presence of mild retinal hemorrhages in addition to microaneurysms was sufficiently less severe than the presence of hard or soft exudates to merit designatio ...
Retinal Pigment Epithelium as a Barrier in Drug Permeation and as
... retina. As a part of the blood-retina barrier, RPE restricts the molecules from blood flow and outer ocular layers from gaining access to the neural retina. Many retinal diseases may be relieved by delivery of neuroprotective or antiangiogenic factors to the retina. RPE is an interesting target for ...
... retina. As a part of the blood-retina barrier, RPE restricts the molecules from blood flow and outer ocular layers from gaining access to the neural retina. Many retinal diseases may be relieved by delivery of neuroprotective or antiangiogenic factors to the retina. RPE is an interesting target for ...
Mechanical ocular trauma - IS MU
... shorter the wound, the less energy to be lost during penetration. Mechanical Intraocular Damage Little or no damage is expected if the IOFB has completely lost its kinectic energy upon entry. The primary impact may be followed by additional impaction via ricocheting. ...
... shorter the wound, the less energy to be lost during penetration. Mechanical Intraocular Damage Little or no damage is expected if the IOFB has completely lost its kinectic energy upon entry. The primary impact may be followed by additional impaction via ricocheting. ...
as a PDF
... ARMD) also nonspecifically binds to all VEGF isoforms. Pegaptamib is an aptamer, a synthetic oligonucleotide with three-dimensional conformation capable of binding to a wide range of molecular targets. Pegaptamib is capable of selective binding to VEGF165, the isoform responsible for pathologic ocul ...
... ARMD) also nonspecifically binds to all VEGF isoforms. Pegaptamib is an aptamer, a synthetic oligonucleotide with three-dimensional conformation capable of binding to a wide range of molecular targets. Pegaptamib is capable of selective binding to VEGF165, the isoform responsible for pathologic ocul ...
Mark J. Mannis, MD
... Research in the United States. In 2012, 45 UC Davis faculty, with nearly $22M in grant support, studied all aspects of visual function, from molecular biology of the cornea, to visual cognition in the brain, from nano-engineering of the trabecular meshwork, to stem cell treatment for retinal disease ...
... Research in the United States. In 2012, 45 UC Davis faculty, with nearly $22M in grant support, studied all aspects of visual function, from molecular biology of the cornea, to visual cognition in the brain, from nano-engineering of the trabecular meshwork, to stem cell treatment for retinal disease ...
Session 325 Clinical Imaging
... cases had the greatest retinal thinning and the most delayed MfERG latency compared to other dementia. Conclusions: These findings provide evidence that there is a decline in retinal structure and function in AD. We speculate this extent of decline results from a chronic process, and could have star ...
... cases had the greatest retinal thinning and the most delayed MfERG latency compared to other dementia. Conclusions: These findings provide evidence that there is a decline in retinal structure and function in AD. We speculate this extent of decline results from a chronic process, and could have star ...
Jeannerod (1979) Corollary discharge. Its possible
... three studies were very similar despite differences in data processing and elicitation of eye movements (spontaneous or of vestibular origin). In the dark, the effect of eye movements could be either excitatory or inhibitory, starting 30-40 msec after the onset of the saccade, and lasting up to 160- ...
... three studies were very similar despite differences in data processing and elicitation of eye movements (spontaneous or of vestibular origin). In the dark, the effect of eye movements could be either excitatory or inhibitory, starting 30-40 msec after the onset of the saccade, and lasting up to 160- ...
For macular edema following branch or central retinal vein occlusion
... affects the central part of the retina (the macula), it is called macular edema, which may reduce your central vision. In addition, low oxygen levels may cause fragile new blood vessels to grow, which can also cause vision problems. Untreated retinal vein occlusion can take months to heal and lead t ...
... affects the central part of the retina (the macula), it is called macular edema, which may reduce your central vision. In addition, low oxygen levels may cause fragile new blood vessels to grow, which can also cause vision problems. Untreated retinal vein occlusion can take months to heal and lead t ...
Optical Coherence Tomography in Pediatric Ophthalmology: Current
... gate whether decreased visual acuity in amblyopia can be correlated with anatomical abnormalities in macula and RNFL. Al-Haddad et al studied the macular thickness in amblyopia using SD-OCT.30 Central macular thickness was significantly increased in children with anisometropic amblyopia. Anisometropi ...
... gate whether decreased visual acuity in amblyopia can be correlated with anatomical abnormalities in macula and RNFL. Al-Haddad et al studied the macular thickness in amblyopia using SD-OCT.30 Central macular thickness was significantly increased in children with anisometropic amblyopia. Anisometropi ...
Leading 2nd version.PM
... have existed as the stable ferric ion. As a trace amount of the inert ferric ion diffused into the rats’ ONL, it was reduced by ascorbic acid to ferrous ion. The auto-oxidation of a ferrous ion to ferric ion released a single electron to form the highly toxic superoxide. A continuous turnover of fer ...
... have existed as the stable ferric ion. As a trace amount of the inert ferric ion diffused into the rats’ ONL, it was reduced by ascorbic acid to ferrous ion. The auto-oxidation of a ferrous ion to ferric ion released a single electron to form the highly toxic superoxide. A continuous turnover of fer ...