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With a Heart Murmur - McGraw-Hill Education
With a Heart Murmur - McGraw-Hill Education

... or “acute on chronic” severe MR. MVP may occur as an isolated phenomenon, or the lesion may be part of a more generalized connective tissue disorder as seen, for example, in patients with Marfan syndrome. Acute, severe MR as a consequence of infective endocarditis results from destruction of leaflet ...
The index of suspicion of RV infarction should be particularly high in
The index of suspicion of RV infarction should be particularly high in

... Echocardiography enables assessment of the patient’s volume status which is complementary to, and may be more reliable than measurements performed by traditional invasive hemodynamic monitoring[22-24]. In the ICU, when images are sub-optimal, TEE may allow for a more accurate assessment of intracard ...
Complete Article - Journal of Morphological Science
Complete Article - Journal of Morphological Science

... Mitral orifice is a well-defined zone between the atrial wall and bases of the leaflets. Mitral valve consists of an orifice with its supporting annulus, leaflets, chordae tendinae and papillary muscles (LAWRENCE, BERRY, COLLINS et al., 1992). Mitral annulus is an area where muscular fibres of atriu ...
Outcomes of Minimally Invasive Mitral Valve
Outcomes of Minimally Invasive Mitral Valve

... Whether to perform mitral valve surgery in patients with severe mitral regurgitation and advanced heart failure is controversial. The functional, or secondary, mitral insufficiency noted in these cases is usually a result of annular dilatation, papillary muscle displacement, and chordal tethering, wi ...
Guidelines on the management of valvular heart disease (version 2012)
Guidelines on the management of valvular heart disease (version 2012)

... tricuspid annular plane systolic excursion transcatheter aortic valve implantation transoesophageal echocardiography tricuspid regurgitation tricuspid stenosis transthoracic echocardiography unfractionated heparin valvular heart disease three-dimensional echocardiography ...
Cardiac Anatomy and Physiologic Correlates
Cardiac Anatomy and Physiologic Correlates

... anterior (anterolateral) and posterior (posterior lateral) based upon the consistent relationship that each papillary muscle bears with its respective commissural area (Carpentier Ac, Pc). The anterior papillary muscle is located on the anterior-lateral free wall of the left ventricle. The posterior ...
Guidelines on the management of valvular heart disease (version 2012)
Guidelines on the management of valvular heart disease (version 2012)

... tricuspid annular plane systolic excursion transcatheter aortic valve implantation transoesophageal echocardiography tricuspid regurgitation tricuspid stenosis transthoracic echocardiography unfractionated heparin valvular heart disease three-dimensional echocardiography ...
ESC/EACTS Guidelines on valvular heart disease
ESC/EACTS Guidelines on valvular heart disease

... tricuspid annular plane systolic excursion transcatheter aortic valve implantation transoesophageal echocardiography tricuspid regurgitation tricuspid stenosis transthoracic echocardiography unfractionated heparin valvular heart disease three-dimensional echocardiography ...
Full Text:PDF - The Turkish Journal of Pediatrics
Full Text:PDF - The Turkish Journal of Pediatrics

... wheezing and stridor. Cardiovascular system examination revealed a grade 3/6 systolic murmur maximal at upper left sternal border. The second heart sound was single. The electrocardiogram revealed QRS axis of 100°, and right ventricle hypertrophy. The chest X-ray showed normal-sized cardiac silhouet ...
Mitral valve anatomy for Transcatheter techniques
Mitral valve anatomy for Transcatheter techniques

... mal area that has insertions of basal cords to its v surface. Being distant from the ventricular wall, leaflet does not have attachments to basal cords. I Figure 3 A dissection showing the left (L) and right (R) fibrous valve closure, the two leaflets meet each other snugly trigones revealed by remo ...
Left ventricular filling in hypertrophic cardiomyopathy - Heart
Left ventricular filling in hypertrophic cardiomyopathy - Heart

... size on chest radiography, the degree of left ventricular hypertrophy on electrocardiogram, left ventricular end-diastolic pressure, the degree of outflow tract obstruction, and the presence or absence of significant mitral regurgitation. Only 1 patient had been taking propranolol, which was stopped ...
Positive jugular pulse
Positive jugular pulse

... Peripheral circulatory failure is brought about by reduction in blood volume, or by pooling of blood in the peripheral vessels as for example in splanchnic vasodilatation. The end results are similar to those of congestive heart failure although there is no primary defect of the heart itself, the v ...
Asynchronous Atrioventricular Valve Opening as it Relates
Asynchronous Atrioventricular Valve Opening as it Relates

... Early and late diastolic filling waves: role of heart rate. At relatively slow heart rates, <120 beats/min, mitral and tricuspid diastolic flow recordings showed distinct early and late diastolic filling waves (Fig. IA). The onset of the early mitral filling wave preceded the onset of the early tric ...
Impact of Atrioventricular Compliance on Pulmonary Artery Pressure
Impact of Atrioventricular Compliance on Pulmonary Artery Pressure

... a true gold standard.8 Stress echocardiography offered the ideal instrument to test the hypotheses stated in the introduction, because it allows us to relate Cn to an independent parameter of disease severity such as PAP and its response to exercise.17 We found that Cn was closely related to PAP, pa ...
Muscular Subaortic Stenosis: The Temporal
Muscular Subaortic Stenosis: The Temporal

... recorded using a transseptal catheter advanced through the mitral valve orifice into the left ventricular inflow tract and a retrograde catheter in the aortic root. In each case, care was taken to ensure that the recorded intraventricular pressure gradient indicated true outflow tract obstruction, a ...
CURRICULUM VITAE John Alex Elefteriades, M.D. Date of Revision
CURRICULUM VITAE John Alex Elefteriades, M.D. Date of Revision

... He performs all aspects of adult cardiac and thoracic surgery. He is a recognized authority in interventions for the failing left ventricle, including coronary artery bypass grafting, left ventricular aneurysmectomy, and artificial heart implantation. Dr. Elefteriades directs the Aortic Institute at ...
Right Bundle-Branch Block and Left Anterior
Right Bundle-Branch Block and Left Anterior

... Tricuspid valves are being replaced with increasing frequency for rheumatic and traumatic disease as well as for Ebstein's anomaly. 1-15 However, comprehensive studies of conduction disturbances following tricuspid valve replacement have not been reported. The purposes of this study were threefold: ...
Course Book Cardiovascular Disease 2013-2014
Course Book Cardiovascular Disease 2013-2014

... practice. The lectures will be presented by WUSM faculty members with considerable clinical experience and expertise in the topic area. Four of the lectures will deal with therapies considered currently as the standard-of-care for patients with the highlighted condition. When the therapy involves dr ...
Ch26_Disorders of Cardiac Fxn - University of Perpetual Help
Ch26_Disorders of Cardiac Fxn - University of Perpetual Help

... sac.3,4 It can occur as the result of conditions such as trauma, cardiac surgery, cancer, uremia, or cardiac rupture due to myocardial infarction. The seriousness of cardiac tamponade results from increased intracardiac pressure, progressive limitation of ventricular diastolic filling, and reduction ...
AHA Scientific Statement
AHA Scientific Statement

... Although balloon atrial septostomy is usually a safe procedure, complications have been reported. Transient rhythm disturbances are frequent67; on rare occasions they can be permanent or fatal. Premature ectopic beats are the most common, followed by supraventricular tachycardia, atrial flutter, and ...
Clinical Anatomy of the Aorta
Clinical Anatomy of the Aorta

... Tetralogy of Fallot • Four co-occurring heart defects • Pulmonary stenosis • Ventricular septal defect • Overriding aorta (dextroposition) • Right ventricular hypertrophy • Asymmetrical fusion of bulbar & truncal ridges ...
experimental fluid mechanics of pulsatile artificial blood pumps
experimental fluid mechanics of pulsatile artificial blood pumps

... found peak wall shear stresses of less than 30 dynes/cm2 . They concluded that the mean and turbulent flow in the ventricular assist device (VAD) was not high enough to damage blood elements, but that the low wall shear could contribute to thrombus deposition. The pulsed Doppler ultrasound measuremen ...
Large Caseous Mitral Annular Calcification
Large Caseous Mitral Annular Calcification

... Mustafa Aydin, MD ...
Venous Stenosis After Transvenous Lead Placement: A Study of
Venous Stenosis After Transvenous Lead Placement: A Study of

... the clinical course. Supporting this hypothesis is the finding of an increased risk of venous stenosis in patients who had multiple implant procedures. Multiple entries into the venous system causes repetitive trauma to the endothelium that may promote an inflammatory reaction and the cascade of event ...
Cardio85-CardiacMuscleMechanicsPt3
Cardio85-CardiacMuscleMechanicsPt3

... and there is no opposing force, the med school students will be able to run faster than the profs. The med students are synonymous to mm with high contractility. So high contractility results in higher velocity. X. Responses to depressed contractility a. ESV incr because of decreased ejection b. EDV ...
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Aortic stenosis



Aortic stenosis (AS) is the narrowing of the exit of the left ventricle of the heart such that problems result. It may occur at the aortic valve as well as above and below this level. It typically gets worse over time. Symptoms often come on gradually with a decreased ability to exercise often occurring first. If heart failure, loss of consciousness, or heart related chest pain occurs due to AS the outcomes are worse. Loss of consciousness typically occurs with standing or exercise. Signs of heart failure include shortness of breath especially with lying down, at night, and with exercise as well as swelling of the legs. Thickening of the valve without narrowing is known as aortic sclerosis.Causes include being born with a bicuspid aortic valve and rheumatic fever. A bicuspid aortic valve affects about one to two percent of the population while rheumatic heart disease mostly occurring in the developing world. A normal valve, however, may also harden over the decades. Risk factors are similar to those of coronary artery disease and include smoking, high blood pressure, high cholesterol, diabetes, and being male. The aortic valve usually has three leaflets and is located between the left ventricle of the heart and the aorta. AS typically results in a heart murmur. Its severity can be divided into mild, moderate, severe, and very severe based on ultrasound of the heart findings.Aortic stenosis is typically followed using repeated ultrasounds. Once it has become severe treatment primarily involves valve replacement surgery with transcatheter aortic valve replacement (TAVR) being an option in some who are at high risk from surgery. Valves may either be mechanical or bioprosthetic with each having risks and benefits. Another less invasive procedure, balloon aortic valvuloplasty (BAV) may result in benefit but this is for only for a few months. Complications like heart failure may be treated as per normal in those with mild to moderate AS. In those with severe disease a number of medications should be avoided including ACE inhibitors, nitroglycerin, and some beta blockers. Nitroprusside or phenylephrine may be used in those with decompensated heart failure depending on the blood pressure.Aortic stenosis is the most common valvular heart disease in the developed world. It affects about 2% of people who are over 65 years of age. Estimated rates are not known in most of the developing world as of 2014. In those who have symptoms, without repair, the chance of death at five years is about 50% and at 10 years is about 90%. Aortic stenosis was first described by French physician Lazare Rivière in 1663.
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