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origin al ar ticle
origin al ar ticle

... adiponectin levels indicate a higher risk for hyperinsulinemia, insulin resistance and diabetes mellitus. Patients with low serotonin circulation levels produced cor-respondingly low adiponectin serum levels in our investigation with a higher risk for hyperinsulinism and the metabolic syndrome. This ...
Medullary carcinoma
Medullary carcinoma

... • 10%~15% of the pancreatic substance • Each islet contains 1000 cells beta cells alpha cells delta cells PP (pancreatic polypeptide) cells ...
Dear Notetaker:
Dear Notetaker:

... LDL particles, LDL gets to adipose tissue, fatty acids can be taken up o Insulin increases utilization of glucose for energy, thus sparing fats o Insulin increases the production of fatty acids by the liver  Enhances triglyceride synthesis Describe the effects of insulin on fat and protein metaboli ...
Interacting Epidemics * Diabetes Obstructive Sleep Apnea and Type 2
Interacting Epidemics * Diabetes Obstructive Sleep Apnea and Type 2

... revealing an increased risk of developing diabetes in men14 and women13 with habitual snoring at a 10-year follow-up. The increase in the risk of diabetes developing was sevenfold for men, but only twofold for women. Of note, two large cross-sectional studies from Korea17,18 involved only subjects w ...
Efficacy of Troglitazone on Body Fat Distribution in
Efficacy of Troglitazone on Body Fat Distribution in

... We investigated the relationship between efficacy of the drug and body fat distribution. Changes in body fat distribution were also investigated by long-term administration of the drug. RESEARCH DESIGN AND METHODS — Troglitazone was given at a dose of 400 mg/day to 20 patients with type 2 diabetes w ...
Seasonal variation in basal metabolic rates among
Seasonal variation in basal metabolic rates among

... Methods: Anthropometric dimensions, BMR, and thyroid hormone levels (free triiodothyronine [fT3], free thyroxine [fT4], thyroid-stimulating hormone [TSH]) were measured on two occasions (July/August, 2009 and January 2011) on a sample of 94 Yakut (Sakha) adults (35 men, 59 women) from the rural vill ...
Atypical or typical adrenocorticotropic hormone-producing pulmonary carcinoids and the usefulness of 11C-5-hydroxytryptophan
Atypical or typical adrenocorticotropic hormone-producing pulmonary carcinoids and the usefulness of 11C-5-hydroxytryptophan

... 8.00 a.m. (reference <46) and 140ng/L at 7.30 p.m. Sampling of 24-hour urinary free cortisol showed increased values, >3000nmol/24 hour (reference <183). He did not suppress his cortisol or ACTH levels at all on 1mg dexamethasone suppression testing. His chromogranin A levels and blood sugar levels ...
Endoscopic Duodenal Mucosal Resurfacing for the
Endoscopic Duodenal Mucosal Resurfacing for the

... pharmacological interventions, many patients do not achieve adequate control of hyperglycemia (1). Poor compliance with complex medical regimens (2) and the fact that most available pharmaceutical approaches do not adequately address underlying pathophysiological defects may explain the limited effic ...
irritable bowel syndrome – ibs - University of California, Berkeley
irritable bowel syndrome – ibs - University of California, Berkeley

... Add fiber to your diet to help your intestines function normally. Fiber increases intestinal motility to reduce constipation by creating a bulkier bowel movement, and fiber decreases intestinal motility in diarrhea by absorbing excess water from the stool. Dietary fiber includes complex carbohydrate ...
انواع آنزیم دیدیناز و وظیفه اش و محل انجام کار : In most
انواع آنزیم دیدیناز و وظیفه اش و محل انجام کار : In most

... (114,115,164,265), injury (266), chronic infection (261,262) or cancer (267-269) — will have a decreased T4 to T3 conversion in the body and a relative tissue hypothyroidism. The inflammatory cytokines will, however, increase the activity of D2 and suppress the TSH despite reduced peripheral T3 leve ...
Int J Obes (Lond). 2013 - Universidad de Navarra
Int J Obes (Lond). 2013 - Universidad de Navarra

... OBJECTIVE: Thyroid hormone receptor-beta resistance has been associated with metabolic traits. THRA gene sequencing of an obese woman (index case) who presented as empirical thyroid hormone receptor-a (THRA) resistance, disclosed a polymorphism (rs12939700) in a critical region involved in TRa alter ...
endocrinology
endocrinology

... Progression to sxs is 4%/year... Higher if thyroid peroxide antibody positive. Management: Treat with T4. (Progression likely. Q104, MKSAP 12). Treatment of hypothyroidism and monitoring levothyroxine therapy: Bottom line: measure and treat the TSH. Free T4 is insensitive to overtreatment: E.G.: T4 ...
Fasting Plasma Glucose Levels and Endogenous
Fasting Plasma Glucose Levels and Endogenous

... androgens DHEAS and androstenedione, cortisol, oestrone, total and free oestradiol and SHBG were significantly negatively related to age; total testosterone was positively related to age. Only androstenedione, cortisol and SHBG were significantly negatively related to body mass index after adjusting ...
Sex Hormone Bind ing Globulin: The Connection between
Sex Hormone Bind ing Globulin: The Connection between

... The androgen sex hormone, testosterone, by itself or relative to estrogen levels, may be a relative risk factor for CVD in women.11 Exogenous testosterone may negate the benefits of ERT12, and metabolic states with high testosterone or testosterone precursors are associated with increased cardiovasc ...
Thyroid stimulating hormone
Thyroid stimulating hormone

...  Since insulin ↑ utilization of glucose by most cells, causes ↓ utilization of fat, leading to fat storage  In liver cells excess glycogen prevents the further formation of glycogen & the glucose thus entering gets converted to pyruvate by glycolysis & forms ...
Adrenal Cortex
Adrenal Cortex

... Dexamethazone 1 mg is given at 11 PM (should suppress early morning cortisol high secretion). Then, 8-9 AM: serum free cortisol is measured. ...
Insulin and oral hypoglycemic drugs
Insulin and oral hypoglycemic drugs

... Answer to Case 1 ( A newly diagnosed type 2 DM patient with obesity)  Lifestyle intervention  Metformin 500mg q.d.-t.i.d ...
Endocrine System Chart
Endocrine System Chart

... Hypopituitarism any number of causes. Adenomas, tumors sof urrounding pituitary cause the mass effect and obliterate secreting cells. Trauma can also affect secretion. Radiotherapy may cause problems, so too can infarction. Sudden infarction associated with pregnancySheehan’s syndrome. Various inf ...
Faculty Profile - New York Obesity Nutrition Research Center
Faculty Profile - New York Obesity Nutrition Research Center

... I am a Professor of Pediatrics and have been Division Director of Pediatric Endocrinology, Diabetes, and Metabolism at Columbia University Medical Center since 2004. Since 1998, I have been the Program Director of the Fellowship Training program in Pediatric Endocrinology and the PI of a T32 trainin ...
corticosteroids - LaGuardia ePortfolio
corticosteroids - LaGuardia ePortfolio

... healthy also prevent lipodystrophy (a medical condition characterized by abnormal or degenerative conditions of the body's adipose tissue). ...
Diagnosing, Managing Cushing`s Disease: A
Diagnosing, Managing Cushing`s Disease: A

... and 9 AM). A morning plasma cortisol level <1.8 µg/dL effectively rules out Cushing’s syndrome.1 Reducing the cut off from 5 to 1.8 µg/dL improved the sensitivity of this test for Cushing’s syndrome from 82% to 95%. There are reports of occasional patients with Cushing’s syndrome who have demonstrat ...
Insulin resistance index versus glycerol and free
Insulin resistance index versus glycerol and free

... documented that disturbed ovarian hormone secretion and subsequent hyperandrogenism brings about insulin resistance [10,42]. Moreover, insulin sensitivity in females decrease with age and HRT during menopause is known to improve whole-body insulin action [6]. However, lifestyle factors are also know ...
Anterior Segment Findings in Women with Polycystic Ovary Syndrome
Anterior Segment Findings in Women with Polycystic Ovary Syndrome

... Conclusion: PCOS leads to physiological and structural changes in the eye. Dry eye symptoms were more severe and central corneal thickness measurements were greater in patients with PCOS. Those are correlated serum testosterone and estradiol levels. Keywords: Polycystic ovary syndrome, dry eye, corn ...
Pituitary gland disorder by Dr Rubina Mansoor
Pituitary gland disorder by Dr Rubina Mansoor

... Can result from hypothalamic or pituitary disease  Tumours are most common cause  GH and gonadotrophins affected before that of ACTH  May be accompanied by hypofunction of posterior pituitary ...
1. dia
1. dia

... syndrome, delayed sleep-phase syndrome) • non-dipper BP pattern (night-time BP is higher and not lower than day-time value) ...
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Metabolic syndrome



Metabolic syndrome is a clustering of at least three of five of the following medical conditions: abdominal (central) obesity, elevated blood pressure, elevated fasting plasma glucose, high serum triglycerides, and low high-density lipoprotein (HDL) levels. Metabolic syndrome is associated with the risk of developing cardiovascular disease and diabetes. Some studies have shown the prevalence in the USA to be an estimated 34% of the adult population, and the prevalence increases with age.Metabolic syndrome is also known as metabolic syndrome X, cardiometabolic syndrome, syndrome X, insulin resistance syndrome, Reaven's syndrome (named for Gerald Reaven), and CHAOS (in Australia).Metabolic syndrome and prediabetes may be the same disorder, just diagnosed by a different set of biomarkers.The syndrome is thought to be caused by an underlying disorder of energy utilization and storage. The cause of the syndrome is an area of on-going medical research.
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