Longitudinal association of C-reactive protein and Haemoglobin A1c
... had a right skewed distribution and for continuous analysis was log-transformed to obtain a normal distribution. For categorical analyses CRP was divided into 4 clinically relevant categories using cut-points 1, 3, and 10 mg/l. In cross-sectional analysis using baseline data, multiple linear regress ...
... had a right skewed distribution and for continuous analysis was log-transformed to obtain a normal distribution. For categorical analyses CRP was divided into 4 clinically relevant categories using cut-points 1, 3, and 10 mg/l. In cross-sectional analysis using baseline data, multiple linear regress ...
Neonatal Programming of Body Weight Regulation and Energetic
... The leptin resistance, which is observed in programmed offspring, may be a mechanism induced by the experience of a nutrient-deprived intrauterine environment to store large quantities of triglycerides when food is plentiful. Leptin resistance would therefore create a competitive advantage in prepar ...
... The leptin resistance, which is observed in programmed offspring, may be a mechanism induced by the experience of a nutrient-deprived intrauterine environment to store large quantities of triglycerides when food is plentiful. Leptin resistance would therefore create a competitive advantage in prepar ...
PDF - EnM :: Endocrinology and Metabolism
... Ghrelin and leptin are two hormones that may have a significant impact on energy balance [14]. Studies on ghrelin and leptin levels in human thyroid dysfunction yielded highly variable data and inconsistent results. In our study, we did not find any significant differences with respect to mean pla ...
... Ghrelin and leptin are two hormones that may have a significant impact on energy balance [14]. Studies on ghrelin and leptin levels in human thyroid dysfunction yielded highly variable data and inconsistent results. In our study, we did not find any significant differences with respect to mean pla ...
1 Goals and Objectives for sub-specialty training in Pediatric
... Know sources of glucose and basic enzyme systems that regulate storage, oxidation and production of glucose. Know the effect of insulin and counter regulatory hormones on carbohydrate, fat and protein metabolism. Know the criteria for normal blood glucose concentrations in infants, children and adul ...
... Know sources of glucose and basic enzyme systems that regulate storage, oxidation and production of glucose. Know the effect of insulin and counter regulatory hormones on carbohydrate, fat and protein metabolism. Know the criteria for normal blood glucose concentrations in infants, children and adul ...
Changes in glucose, glycogen, thyroid activity and hypothalamic
... glycogen depots, as it occurs in carp (Böhm et al. 1994) and rainbow trout (Figueroa et al. 2000). Nevertheless, the existence of indirect pathways producing glycogenogenesis during refeeding, e.g. from 3-carbon compounds via the gluconeogenic pathway (Baanante et al. 1991), can not be discarded. M ...
... glycogen depots, as it occurs in carp (Böhm et al. 1994) and rainbow trout (Figueroa et al. 2000). Nevertheless, the existence of indirect pathways producing glycogenogenesis during refeeding, e.g. from 3-carbon compounds via the gluconeogenic pathway (Baanante et al. 1991), can not be discarded. M ...
Full Title: Agouti related protein (AgRP) is upregulated in Cushing`s
... sequences in the National Centre for Biotechnology (NCBI) Blast database. ...
... sequences in the National Centre for Biotechnology (NCBI) Blast database. ...
Glucose Metabolism and Regulation: Beyond Insulin and Glucagon
... glycogenolysis is minimal due to low insulin secretion in the fasting state (3). 1B. For nondiabetic individuals in the fed state, plasma glucose is derived from ingestion of nutrients (1). In the bi-hormonal model, glucagon secretion is suppressed through the action of endogenous insulin secretion ...
... glycogenolysis is minimal due to low insulin secretion in the fasting state (3). 1B. For nondiabetic individuals in the fed state, plasma glucose is derived from ingestion of nutrients (1). In the bi-hormonal model, glucagon secretion is suppressed through the action of endogenous insulin secretion ...
Pharmacology/Therapeutics II Block III Lectures 2012
... o Has multiple polyethylene glycol (PEG) residues, which prolongs its half-life Mechanism of Action: o Pegvisomant is a competitive antagonist of GH activity o This can bind to the transmembrane GH receptor but cannot activate subsequent intracellular signaling o It decreases serum IGF1 levels ...
... o Has multiple polyethylene glycol (PEG) residues, which prolongs its half-life Mechanism of Action: o Pegvisomant is a competitive antagonist of GH activity o This can bind to the transmembrane GH receptor but cannot activate subsequent intracellular signaling o It decreases serum IGF1 levels ...
Recurring Acute Abdomen, Ovarian Cyst
... tests in young girls with above clinical profile. Surgery is indicated if there is a complication or failure to medical treatment. We conclude that severe hypothyroidism was probably responsible for various ovarian disorders that might have resulted from the effects of an excess amount of TSH on imm ...
... tests in young girls with above clinical profile. Surgery is indicated if there is a complication or failure to medical treatment. We conclude that severe hypothyroidism was probably responsible for various ovarian disorders that might have resulted from the effects of an excess amount of TSH on imm ...
HYPOTHYROID, Weak Thyroid
... Sometimes even goitrous hypothyroidism can result as a deficiency of TSH or other thyroid hormones or iodine deficiency, among others. Overdosing of carotene or vitamin A can also bring on hypothyroidism. Signs of hypothyroidism include depression, drop in body temperature, eyelid droop because of d ...
... Sometimes even goitrous hypothyroidism can result as a deficiency of TSH or other thyroid hormones or iodine deficiency, among others. Overdosing of carotene or vitamin A can also bring on hypothyroidism. Signs of hypothyroidism include depression, drop in body temperature, eyelid droop because of d ...
PCOS - Hormones.gr
... presupposes the presence of at least two out of the three following features: anovulation (ANOV), clinical and/or biochemical hyperandrogenism (HA) and polycystic ovaries on ultrasonography (PCO),2 with other androgen excess disorders excluded. Subsequently, additional milder phenotypes of the syndr ...
... presupposes the presence of at least two out of the three following features: anovulation (ANOV), clinical and/or biochemical hyperandrogenism (HA) and polycystic ovaries on ultrasonography (PCO),2 with other androgen excess disorders excluded. Subsequently, additional milder phenotypes of the syndr ...
Full Text - International Journal of High Risk Behaviors and
... established. However, it has been proposed that low concentrations of serum adiponectin observed in obese subjects (10, 21, 22, 25, 26) might contribute to the development of atherosclerosis and cardiovascular diseases (8, 12, 13, 16, 17). There is evidence that adiponectin affects the regulation of ...
... established. However, it has been proposed that low concentrations of serum adiponectin observed in obese subjects (10, 21, 22, 25, 26) might contribute to the development of atherosclerosis and cardiovascular diseases (8, 12, 13, 16, 17). There is evidence that adiponectin affects the regulation of ...
Insulin Resistance of Protein Metabolism in Type 2 Diabetes
... in 17 hyperglycemic type 2 diabetic subjects and 23 subjects without diabetes matched for age and body composition, after 7 days on a inpatient, protein-controlled, isoenergetic diet. Glucose and leucine kinetics were determined using tracers. RESULTS—In type 2 diabetes, postabsorptive (baseline) gl ...
... in 17 hyperglycemic type 2 diabetic subjects and 23 subjects without diabetes matched for age and body composition, after 7 days on a inpatient, protein-controlled, isoenergetic diet. Glucose and leucine kinetics were determined using tracers. RESULTS—In type 2 diabetes, postabsorptive (baseline) gl ...
ENDOCRINOLOGY
... – May compromise optic pathways – leading to impaired visual acuity and visual field defects ...
... – May compromise optic pathways – leading to impaired visual acuity and visual field defects ...
Een 50 jarige man wordt verwezen vanwege plotseling
... At the initial presentation, all patients should undergo biochemical screening to ascertain their thyroid status, usually by checking thyroid-stimulating hormone (TSH) levels (9). When TSH levels are normal, assay of free T4 adds no further information. A suppressed TSH, implying a hyper-functioning ...
... At the initial presentation, all patients should undergo biochemical screening to ascertain their thyroid status, usually by checking thyroid-stimulating hormone (TSH) levels (9). When TSH levels are normal, assay of free T4 adds no further information. A suppressed TSH, implying a hyper-functioning ...
Defining the Ideal Injection Techniques When Using 5
... worth noting that among individuals who experience discomfort, children had higher scores than adults. Needle aversion and phobia appear to be common in children with diabetes (17), and pain associated with daily injections is said to be important in discouraging patients to adhere to treatment (18) ...
... worth noting that among individuals who experience discomfort, children had higher scores than adults. Needle aversion and phobia appear to be common in children with diabetes (17), and pain associated with daily injections is said to be important in discouraging patients to adhere to treatment (18) ...
ESPE Classification of Paediatric Endocrine Diagnoses
... individual patients in their files and registries. This can then improve patient care, because it makes information about the natural history and treatment responses available of patients that had been seen in the past. It can also be helpful for scientific research, for example in collecting data on ...
... individual patients in their files and registries. This can then improve patient care, because it makes information about the natural history and treatment responses available of patients that had been seen in the past. It can also be helpful for scientific research, for example in collecting data on ...
Diseases of the endocrine system
... mitotic activity and are designated atypical adenomas to reinforce their potential for aggressive behavior. ...
... mitotic activity and are designated atypical adenomas to reinforce their potential for aggressive behavior. ...
Computed Tomography and Magnetic Resonance Imaging
... Background: Computed tomography (CT) and magnetic resonance imaging (MRI) provide important research opportunities due to their unique capability of characterizing and quantifying tissues and organs. Ionizing radiation is a limitation using CT, and recent developments aiming to improve MRI for deter ...
... Background: Computed tomography (CT) and magnetic resonance imaging (MRI) provide important research opportunities due to their unique capability of characterizing and quantifying tissues and organs. Ionizing radiation is a limitation using CT, and recent developments aiming to improve MRI for deter ...
Group A amenorrhea
... Polycystic ovary disease is a common disease resulting in secondary amenorrhea. However, Cushing's disease, a hormonal disorder that occurs when the body’s tissues are revealed to high levels of cortisol and most commonly resulting from benign pituitary adenomas, should also be considered. Therefor ...
... Polycystic ovary disease is a common disease resulting in secondary amenorrhea. However, Cushing's disease, a hormonal disorder that occurs when the body’s tissues are revealed to high levels of cortisol and most commonly resulting from benign pituitary adenomas, should also be considered. Therefor ...
Relationship between TSH, T4, T3 and Prolactin in overweight and
... common endocrinopathy of women of reproductive age, is associated with the early appearance of multiple risk factors for cardiovascular disease, such as abdominal obesity[19]. The present study revealed significantly high TSH level in PCOS patients in contrast to controls (p < 0.001). Based on Garbe ...
... common endocrinopathy of women of reproductive age, is associated with the early appearance of multiple risk factors for cardiovascular disease, such as abdominal obesity[19]. The present study revealed significantly high TSH level in PCOS patients in contrast to controls (p < 0.001). Based on Garbe ...
Managing Subclinical Hypothyroid Using Resting
... Subclinical Hypothyroid and Risk Literature reviews from searches done on MedLine until 5/1/05 revealed: Cardiovascular Risk Several investigators have shown an increase in dyslipidemia, homocysteine, C-reactive protein, coronary artery disease, hypertension, and ischemic heart disease in people wit ...
... Subclinical Hypothyroid and Risk Literature reviews from searches done on MedLine until 5/1/05 revealed: Cardiovascular Risk Several investigators have shown an increase in dyslipidemia, homocysteine, C-reactive protein, coronary artery disease, hypertension, and ischemic heart disease in people wit ...
Upregulated insulin secretion in insulin-resistant
... pmol/l, P<0.001) levels in plasma (Table 1). Furthermore, we observed impaired glucose tolerance after mixed meal challenge in the high-fat compared to control diet fed mice, as indicated by higher sAUC glucose over 60 min (347±33 versus 233±22 mmol/l x min, P=0.007) and reduced KG (0.43±0.03 versus ...
... pmol/l, P<0.001) levels in plasma (Table 1). Furthermore, we observed impaired glucose tolerance after mixed meal challenge in the high-fat compared to control diet fed mice, as indicated by higher sAUC glucose over 60 min (347±33 versus 233±22 mmol/l x min, P=0.007) and reduced KG (0.43±0.03 versus ...
Feline Diabetes Mellitis – The 2010 approach
... food, to get a slow and gradual weight loss. By reducing obesity, we improve insulin sensitivity and by switching them to a so-called diabetic diet, we actually can enhance beta cell health and, hopefully resume normal function. There is a 4x higher likelyhood to achieve remission in cats on low rat ...
... food, to get a slow and gradual weight loss. By reducing obesity, we improve insulin sensitivity and by switching them to a so-called diabetic diet, we actually can enhance beta cell health and, hopefully resume normal function. There is a 4x higher likelyhood to achieve remission in cats on low rat ...
insulin and glucagon responses in the hibernating black bear
... injection during the summer and fall active phases, and also during the late hibernationphase. In contrast, during the early hibernation phase, the glucose response was delayed and the maximum decrease was greater. The return to baseline glucose levels also took longer during the early hibernationph ...
... injection during the summer and fall active phases, and also during the late hibernationphase. In contrast, during the early hibernation phase, the glucose response was delayed and the maximum decrease was greater. The return to baseline glucose levels also took longer during the early hibernationph ...
Metabolic syndrome
Metabolic syndrome is a clustering of at least three of five of the following medical conditions: abdominal (central) obesity, elevated blood pressure, elevated fasting plasma glucose, high serum triglycerides, and low high-density lipoprotein (HDL) levels. Metabolic syndrome is associated with the risk of developing cardiovascular disease and diabetes. Some studies have shown the prevalence in the USA to be an estimated 34% of the adult population, and the prevalence increases with age.Metabolic syndrome is also known as metabolic syndrome X, cardiometabolic syndrome, syndrome X, insulin resistance syndrome, Reaven's syndrome (named for Gerald Reaven), and CHAOS (in Australia).Metabolic syndrome and prediabetes may be the same disorder, just diagnosed by a different set of biomarkers.The syndrome is thought to be caused by an underlying disorder of energy utilization and storage. The cause of the syndrome is an area of on-going medical research.