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Wound model of myocardial infarction - AJP
Wound model of myocardial infarction - AJP

... today (3). The initial event is frequently a large or recurrent myocardial infarction. Acute myocardial infarction starts with thrombotic occlusion of a coronary artery, develops during several hours, and terminates when necrosis has reached its ultimate extension, which is defined by the boundary o ...
Hypertension and Coronary Occlusion
Hypertension and Coronary Occlusion

... the age of 25 to 39 mg. per 100 cc. at the age of 30, and remains at that high level until the sixtieth year. In women, on the contrary, the rise is slow between the age of 25 and 60. Only at the age of 60, do women attain the high figure which men have at the age of 30. This, too, may account for t ...
Anginal Pectoris Refractory to Standard Medical Therapy
Anginal Pectoris Refractory to Standard Medical Therapy

... High risk co-morbidities with excessive risk ...
Angiotensin-Receptor Blockade in Acute Myocardial Infarction — A
Angiotensin-Receptor Blockade in Acute Myocardial Infarction — A

... How will the results of the study by Pfeffer et al. affect the care of high-risk patients after acute myocardial infarction? Given that valsartan was as effective as captopril in reducing the rates of death and other cardiovascular events, the ultimate question raised by this trial is whether high-r ...
PCI farahani ersali
PCI farahani ersali

... with a substantial risk of subsequent development of congestive heart failure and reduced survival of patients similar to what happens in systolic dysfunction (1). The prevalence of diastolic dysfunction is more than systolic dysfunction and is increased with aging (2). This point is more important ...
Predictors Of Depressed Left Ventricular…….
Predictors Of Depressed Left Ventricular…….

... Patient and methods: This study was done in Cardiology department, Zagazig University on 100 patients; 78 males (78%) & 22 females (22%) with first acute STEMI underwent successful primary percutaneous intervention (pPCI). Within 72 hours of admission, all of the following parameters were reported: ...
Adverse Cardiovascular Events Temporally Associated With Ma
Adverse Cardiovascular Events Temporally Associated With Ma

... related to the use of dietary supplements containing ma huang, 47% involved the cardiovascular system and 18% the central nervous system.8 The pathogenesis of ma huang toxicity remains incompletely defined. Ma huang (Ephedra) has been used in traditional Chinese medicine for more than 5 millennia.12 ...
cardiogenic shock
cardiogenic shock

... be used if patient has adequate blood pressure and adequate kidney function. Goal: Decrease preload and pulmonary congestion Mechanical-assist device placed in aorta that increases coronary artery and end organ perfusion and decreases afterload, which improves CO and decreases myocardial oxygen dema ...
Anticoagulants, Thrombolytics Agents and Antiplatelet Drugs
Anticoagulants, Thrombolytics Agents and Antiplatelet Drugs

... platelet aggregation on the first day, and inhibition reaches steady state between Day 3 and Day 7. Platelet aggregation and bleeding time gradually return to baseline values after treatment is discontinued, generally in about 5 days. ...
ION - Boston Scientific
ION - Boston Scientific

... Contents supplied STERILE using an ethylene oxide (EO) process. Do not use if sterile barrier is damaged. If damage is found, call your Boston Scientific representative. For single use only. Do not reuse, reprocess or resterilize. Reuse, reprocessing or resterilization may compromise the structural ...
Myocardial ischemia
Myocardial ischemia

... Affected by peripheral vascular resistance and arterial pressure. ...
June - North American - Congenital Cardiology Today
June - North American - Congenital Cardiology Today

... more effective than medical therapy, to date, it has not been shown to positively impact survival and in fact, may result in significant long-term sequelae.15-16 Several recent large studies have suggested that ligation is independently associated with the development of chronic lung disease and neu ...
Modified thromboelastography evaluation of platelet dysfunction in
Modified thromboelastography evaluation of platelet dysfunction in

... Objective: Anti-platelet therapy is associated with increased perioperative bleeding. Although current guidelines call for its caessation 5—10 days prior to cardiac surgery, this could constitute an increased risk of preoperative myocardial infarction. The optimal safe period from discontinuation of ...
Roles of Nuclear Cardiology, Cardiac Computed Tomography, and
Roles of Nuclear Cardiology, Cardiac Computed Tomography, and

... purposes of risk assessment of asymptomatic patients with intermediate clinical risk. There is now widespread support that third-party carriers should pay for testing in this patient group rather than having it be a test only for patients who can afford to pay for it. Although several reports have s ...
Ticagrelor versus Clopidogrel in Patients with Acute Coronary
Ticagrelor versus Clopidogrel in Patients with Acute Coronary

... population) were the composite of death from any cause, myocardial infarction, or stroke; the composite of death from vascular causes, myocardial infarction, stroke, severe recurrent cardiac ischemia, recurrent cardiac ischemia, transient ischemic attack, or other arterial thrombotic events; myocard ...
The new england journal of medicine
The new england journal of medicine

... population) were the composite of death from any cause, myocardial infarction, or stroke; the composite of death from vascular causes, myocardial infarction, stroke, severe recurrent cardiac ischemia, recurrent cardiac ischemia, transient ischemic attack, or other arterial thrombotic events; myocard ...
biodiversity of the coronary arteries in cattle
biodiversity of the coronary arteries in cattle

... *Corresponding author: [email protected] Abstract Lately, experimental medicine used the ruminants as experimental animals. On the sheep were achieved even heart experimental surgery. However, the literature about the vascularization of the heart is not very numerous especially regarding l ...
S1936878X15002648_mmc1 - JACC: Cardiovascular Imaging
S1936878X15002648_mmc1 - JACC: Cardiovascular Imaging

... MR image analyses The images were analyzed on a Siemens work-station by observers with at least 3 years CMR experience (N.A., D.C., I.M, S.R.). All of the images were reviewed by experienced CMR cardiologists (C.B., N.T.). LV dimensions, volumes and ejection fraction were quantified using computer a ...
The J-Curve Between Blood Pressure and Coronary Artery
The J-Curve Between Blood Pressure and Coronary Artery

... almost a century ago by stating “Because in this disease the increase in tone of the small arteries in the whole body (which leads to an increase in blood pressure) is the primary event . . . I will, in the following, name this disease, essential hypertension (essentielle Hypertonie).” The concept o ...
107660-0101 NIACOR® (Niacin Tablets, USP) 500 mg - Upsher
107660-0101 NIACOR® (Niacin Tablets, USP) 500 mg - Upsher

... The Cholesterol-Lowering Atherosclerosis Study (CLAS) was a randomized, placebo-controlled, angiographic trial testing combined colestipol and nicotinic acid therapy in 162 non-smoking males with previous coronary bypass surgery3. The primary, per subject cardiac endpoint was global coronary artery ...
High prevalence of acute myocardial damage in a hospital necropsy
High prevalence of acute myocardial damage in a hospital necropsy

... availability of a histological block of left ventricle. This meant that the technique of necropsy examination, the necropsy report, and the part of the myocardium we studied were not uniform between cases, because several pathologists performed and recorded the necropsies and chose the blocks. There ...
Downloaded - UNM Hospitalist Wiki
Downloaded - UNM Hospitalist Wiki

... overall extent and severity of coronary atheroscleosis.8 Studies such as CORE 64 (Coronary Artery Evaluation Using 64Row Multidetector Computed Tomographic Angiography) have demonstrated a high correlation between CCTA and invasive coronary angiography in the determination of CAD extent and severity ...
Community of 30,000
Community of 30,000

... of all the necropsies; perhaps more meaningful than this would be the 32 per cent incidence of such disease for all persons 20 years of age or older examined at necropsy. Coronary heart disease was the cause of death in 151 (41 per cent) of the 373 adult males and 70 (22 per cent ) of the 318 adult ...
Effects of Polyunsaturated Omega-3 Fatty Acids on
Effects of Polyunsaturated Omega-3 Fatty Acids on

... independent investigator on a double-blind basis to receive 75 mg clopidogrel once daily, 75 mg aspirin once daily, and 1,000 mg omega-3 PUFAs once daily (Omacor, Pronova Biocare AS/Solvay Pharma, Warsaw, Poland) or 75 mg clopidogrel once daily, 75 mg aspirin once daily, and placebo for 4 weeks (Fig ...
Open-chest Models of Acute Myocardial Ischemia and Reperfusion
Open-chest Models of Acute Myocardial Ischemia and Reperfusion

... The surgical occlusion of a coronary artery (see Figs. 1 and 2) with consequent myocardial infarction has been performed in many species during the past 50 years, including dogs, pigs, cats and rabbits. Since the use of small rodents is less expensive and keeps drug consumption low, models of corona ...
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Drug-eluting stent



A drug-eluting stent (DES) is a peripheral or coronary stent (a scaffold) placed into narrowed, diseased peripheral or coronary arteries that slowly releases a drug to block cell proliferation. This prevents fibrosis that, together with clots (thrombi), could otherwise block the stented artery, a process called restenosis. The stent is usually placed within the peripheral or coronary artery by an interventional cardiologist or interventional radiologist during an angioplasty procedure.Drug-eluting stents in current clinical use were approved by the FDA after clinical trials showed they were statistically superior to bare-metal stents for the treatment of native coronary artery narrowings, having lower rates of major adverse cardiac events (usually defined as a composite clinical endpoint of death + myocardial infarction + repeat intervention because of restenosis). The first drug-eluting stents to be approved in Europe and the U.S. were coated with paclitaxel or an mTOR inhibitor, such as sirolimus.
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