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L6 Proteins of cereals and legumes - e
L6 Proteins of cereals and legumes - e

... charge of proteins as well as that of the phytic acid is negative – direct interaction would be impossible, however, interaction may occur through the formation of complexes with divalent such as Ca2+ or Mg2+. ...
Calliphorin, a Protein Involved in the Cuticle Formation
Calliphorin, a Protein Involved in the Cuticle Formation

... blowflies, its physiological significance is still un­ known. It is generally thought that calliphorin may be a storage protein which functions as a source of nutrients for adult proteins. It may also play a role in providing haemolymph with amino acids to sustain osmotic pressure. Considering the f ...
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CARBOXYL GROUPS The δ- and ε-carboxyl
CARBOXYL GROUPS The δ- and ε-carboxyl

... 1.33 M glycine methyl ester, and 7.5 M urea is kept at 25° in a water-jacketed vessel attached to a pH-stat. A solution of 0.40 M carbodiimide [i.e., l-benzyl-3-(3dimethylaminopropyl) carbodiimide or l-ethyl-3-(3-dimethylaminopropyl) carbodiimide] in 7.5 M urea is then added to a concentration of re ...
The Exocytic/Lysosomal Transport Pathway
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ORGANELLE-SPECIFIC PROTEIN QUALITY CONTROL SYSTEMS

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ERC funds Polish research into genetic material repair pathways

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... positions showing little coevolution (Gloor, 2005). Coevolving positions fall into two general categories. One set is composed of positions that coevolve with only one or two other positions. These positions often display direct amino acid side-chain interactions with their coevolving partner. The o ...
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Essential Cell Biology

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Instructor: Brendan Leezer

... Nucleic Acids = A complex macromolecule that stores cellular information in the form of a code.  They are also necessary for life.  They are polymers made of smaller subunits called nucleotides. o Nucleotides consist of carbon, hydrogen, oxygen, nitrogen, and phosphorus atoms arranged in three gro ...
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Protein–protein interaction



Protein–protein interactions (PPIs) refer to physical contacts established between two or more proteins as a result of biochemical events and/or electrostatic forces.In fact, proteins are vital macromolecules, at both cellular and systemic levels, but they rarely act alone. Diverse essential molecular processes within a cell are carried out by molecular machines that are built from a large number of protein components organized by their PPIs. Indeed, these interactions are at the core of the entire interactomics system of any living cell and so, unsurprisingly, aberrant PPIs are on the basis of multiple diseases, such as Creutzfeld-Jacob, Alzheimer's disease, and cancer.PPIs have been studied from different perspectives: biochemistry, quantum chemistry, molecular dynamics, signal transduction, among others. All this information enables the creation of large protein interaction networks – similar to metabolic or genetic/epigenetic networks – that empower the current knowledge on biochemical cascades and disease pathogenesis, as well as provide putative new therapeutic targets.
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