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Basic Biochemistry Powerpoint
Basic Biochemistry Powerpoint

... Inorganic Molecules do not contain carbon but do have other important roles (water, salts, and many acids and bases) ...
Gene Ontology Annotation (UniProt-GOA) - EMBL-EBI
Gene Ontology Annotation (UniProt-GOA) - EMBL-EBI

... created by groups such as HAMAP, InterPro, Ensembl Compara, etc. using sequence and structure similarity as well as phylogenetic relationships. As shown in Figure 2, in October 2013 there were ~196,000,000 GO annotations to ~ 30,000,000 proteins, covering ~ 431,000 taxonomic groups. Fig. 2 Number of ...
amino acids
amino acids

... groups are headed to the outer surface. ...
Leukaemia Section t(3;3)(q27;q28) Atlas of Genetics and Cytogenetics in Oncology and Haematology
Leukaemia Section t(3;3)(q27;q28) Atlas of Genetics and Cytogenetics in Oncology and Haematology

... domain (amino acids 1-130 (32-99 according to SwissProt) which mediates homo-dimerization and proteinprotein interactions with other corepressors (including HDAC1 and NCOR2/SMRT ) to constitute a large repressing complex, another transcription repression domain (191-386), PEST sequences (300-417) wi ...
Preview Sample 2
Preview Sample 2

... The side chain represented by the R group Hydrophobic groups are C-H and C-S; Hydrophilic groups are C-OH and ionized amino and carboxyl groups. The L form is found in proteins A carboxyl and amino group. The primary structure The secondary structure which is determined by the primary structure Heat ...
Exam 1
Exam 1

... In nature horses and donkeys will interbreed and produce sterile mules as offspring. Thus by definition, horses and donkeys are members of the different species. ...
Membranlar - mustafaaltinisik.org.uk
Membranlar - mustafaaltinisik.org.uk

... • Lateral Asymmetry of Proteins: – Proteins can associate and cluster in the plane of the membrane - they are not ...
Protein folding
Protein folding

... Suppose that he has to produce, not the complete works of Shakespeare but just the short sentence 'Methinks it is like a weasel', and we shall make it relatively easy by giving him a typewriter with a restricted keyboard, one with just the 26 (capital) letters, and a space bar. How long will he take ...
M4434 Applied Microbiology - Universität Düsseldorf: Biologie
M4434 Applied Microbiology - Universität Düsseldorf: Biologie

PDF - Bioinformation
PDF - Bioinformation

... structural and functional analyses of the gene responsible of their degradation are an important aspect for environmental studies and are important to human well-being. It has been shown that some haloacids are toxic and mutagenic. Microorganisms capable of degrading these haloacids can be found in ...
Arabidopsis is a facultative long day plant which flowers earlier in
Arabidopsis is a facultative long day plant which flowers earlier in

... normal flowering response to photoperiod. The DNF gene is only expressed at a very precise time of the day (4-6h after dawn) and this is critical for the photoperiodic response. The DNF gene encodes a small protein of unknown function but has a domain showing some homology to a RING H-2 finger domai ...
Mutation analysis of a recombinant NS replicon shows that influenza
Mutation analysis of a recombinant NS replicon shows that influenza

... Tandem Affinity Tag Purification based proteomic approach and identified 20 possible NEP interacting cellular partners that may have functional relevance in RNP trafficking, Pol-II transcriptional control, Janus kinase signaling, and the mitochondria ATP homeostasis. We report here that NEP interact ...
GPCR and G Proteins
GPCR and G Proteins

... Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. In mammals, G protein, and subunits are encoded by at least 21, 6 and 12 different genes, respectively. The α subunit binds and can slowly hydrolyze GTP. 4 G protein classes (Gi/Go, Gq, Gs ...
IDENTIFICATION OF A BACTERIO
IDENTIFICATION OF A BACTERIO

... 2. Radioactively labelled lysine, tyrosine and valine could not be ~corporated into peptide IV; the known sequence data show this peptide to lack these amino acids (as well as Ser, Phe, Asx). No other BrCN peptide lacks this combination of amino acids. 3. The amino acid analysis of purified peptide ...
Protein Synthesis -Transcription - Mr. Lesiuk
Protein Synthesis -Transcription - Mr. Lesiuk

... Before the newly made (primary) mRNA is shipped out of the nucleus it must be processed by RIBOZYMES. These Ribozymes (a bit like enzymes) cut out the useless Introns and splice back together the ...
AP Biology
AP Biology

... 14. Draw two amino acids – note the amino group, the carboxyl group and the alpha carbon, circle the water molecule to be removed and then note the peptide bond formed when the two are joined. ...
LECTURES 5, 6 Membrane protein lecture
LECTURES 5, 6 Membrane protein lecture

... –  Receptors – collect signal, pass on to the inside of cell ...
Homology Detection
Homology Detection

... Due to the relatively minor size of protein structure space, similar structures are more likely to originate by convergence However, structure diverges more slowly and therefore allows for the recognition of more distant relationships Functional residues within an active site are often the most high ...
Introduction into Cell Metabolism 1
Introduction into Cell Metabolism 1

... 53. Which of cytoskeleton fibres are longest? 54. Which cytoskeleton filaments does colchicine bind to? What is its effect? 55. What is the role of kinesin and dynein in the cell? ...
Mutation of exposed hydrophobic amino acids to arginine to
Mutation of exposed hydrophobic amino acids to arginine to

... small. This is in accordance with literature, amino acid substitution usually does not significantly affect the stability [10,19], although important improvements of stability by mutagenesis of a single solvent-exposed residue have been reported [20,21]. Several mutations stabilize the protein. A po ...
Supplementary Material Recovery of the first full
Supplementary Material Recovery of the first full

... translation products and proteins encoded by 43 RefSeq genomes of poxviridae family members. Translation products from 120 open reading frames of seal parapoxvirus (left columns) were aligned to proteins encoded by all annotated coding sequences (CDS) of 43 fully sequenced poxvirus genomes deposited ...
Protein core - Acsu.buffalo.edu
Protein core - Acsu.buffalo.edu

... Lambda repressor : binds DNA from bacteriophage Bovine pancreatic trypsin inhibitor (BPTI) ...
Signal sequence
Signal sequence

... Chloroplast stromal protein targeting • Sequence: no common motifs, generally rich in Ser, Thr, and small hydrophobic residues and poor in Glu and Asp. • Import process is similar to mitochondria matrix protein import but import proteins are different. • Chloroplast stroma does not have proton moti ...
What is a Protein?
What is a Protein?

... “R” represents the “Radical” side chain that is different for each amino acid. The “R” group can either be one atom (H) or a group of atoms. ...
HPER 334 Nutrition Exam 2
HPER 334 Nutrition Exam 2

... 43. Exercise has a very strong insulin-like effect. 44. An example of a food that contains a complete protein is peanut butter. 45. The catabolism of protein can produce ammonia, a product that is toxic to the body. 46. It has been proven that protein supplements are more effective than food protein ...
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Protein–protein interaction



Protein–protein interactions (PPIs) refer to physical contacts established between two or more proteins as a result of biochemical events and/or electrostatic forces.In fact, proteins are vital macromolecules, at both cellular and systemic levels, but they rarely act alone. Diverse essential molecular processes within a cell are carried out by molecular machines that are built from a large number of protein components organized by their PPIs. Indeed, these interactions are at the core of the entire interactomics system of any living cell and so, unsurprisingly, aberrant PPIs are on the basis of multiple diseases, such as Creutzfeld-Jacob, Alzheimer's disease, and cancer.PPIs have been studied from different perspectives: biochemistry, quantum chemistry, molecular dynamics, signal transduction, among others. All this information enables the creation of large protein interaction networks – similar to metabolic or genetic/epigenetic networks – that empower the current knowledge on biochemical cascades and disease pathogenesis, as well as provide putative new therapeutic targets.
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