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BIOCHEMISTRY 2.1
BIOCHEMISTRY 2.1

... •Include meat, fish, nuts; provide 4 Cal/gram •Most complex organic molecules •made of CHON Some also contain S, P, Fe, or Cu •COMPOSED OF SMALLER MOLECULES/SUBUNITS CALLED AMINO ...
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Protein Information Tutorial

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CHEM523 Protein Assignment Review Article Grading Rubric

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Project Abstract (150 words max): Scientific Inquiry: The protein

... structure of a cell. Mutations associated within the Ig4 domain of palladin have been observed in pancreatic cancer. In the hydrophobic core of the mutated Ig4 domain the amino acid tryptophan has been replaced with the amino acid cysteine, and we hypothesize that the mutation will affect the struct ...
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Protein–protein interaction



Protein–protein interactions (PPIs) refer to physical contacts established between two or more proteins as a result of biochemical events and/or electrostatic forces.In fact, proteins are vital macromolecules, at both cellular and systemic levels, but they rarely act alone. Diverse essential molecular processes within a cell are carried out by molecular machines that are built from a large number of protein components organized by their PPIs. Indeed, these interactions are at the core of the entire interactomics system of any living cell and so, unsurprisingly, aberrant PPIs are on the basis of multiple diseases, such as Creutzfeld-Jacob, Alzheimer's disease, and cancer.PPIs have been studied from different perspectives: biochemistry, quantum chemistry, molecular dynamics, signal transduction, among others. All this information enables the creation of large protein interaction networks – similar to metabolic or genetic/epigenetic networks – that empower the current knowledge on biochemical cascades and disease pathogenesis, as well as provide putative new therapeutic targets.
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