Multiple Sequence Alignments and Sequence Profiles
... (structural alignments) – See course website for many more listings… ...
... (structural alignments) – See course website for many more listings… ...
the simple quad method - New Moon Family Acupuncture
... Carbohydrate, and a small amount of Fat. Your serving size for the entire meal should be about the size of your two hands cupped together. This is the amount that your stomach can comfortably handle at each meal. An example would be baked chicken, cooked carrots, salad and a small baked potato. Or g ...
... Carbohydrate, and a small amount of Fat. Your serving size for the entire meal should be about the size of your two hands cupped together. This is the amount that your stomach can comfortably handle at each meal. An example would be baked chicken, cooked carrots, salad and a small baked potato. Or g ...
report on HMM
... other to resemble a twisted ladder whose sides, made of sugar and phosphate molecules, are connected by rungs of nitrogen containing chemicals called bases. Four different bases are present in DNA: adenine (A), thymine (T), cytosine (C), and guanine (G). The particular order of the bases arranged al ...
... other to resemble a twisted ladder whose sides, made of sugar and phosphate molecules, are connected by rungs of nitrogen containing chemicals called bases. Four different bases are present in DNA: adenine (A), thymine (T), cytosine (C), and guanine (G). The particular order of the bases arranged al ...
G5. Strategies for Stabilization of Enzymes in Organic
... Enzymes are used in the industrial biocatalysis in wide variety of applications. These vary from synthesis of pharmaceuticals to large-scale production of biofuels. Most important biocatalysts are hydrolases, particularly lipases, since they are able to convert wide variety of substances. They have ...
... Enzymes are used in the industrial biocatalysis in wide variety of applications. These vary from synthesis of pharmaceuticals to large-scale production of biofuels. Most important biocatalysts are hydrolases, particularly lipases, since they are able to convert wide variety of substances. They have ...
Nutritional Impact on Protein Metabolism of Muscle and
... The word protein was coined by Jons J. Berzselius, The famous Swedish chemist in 1838 and derived from the Greek work Proteios (meaning of the first rank). Proteins include several important cell constituents such as enzymes, peptide hormones, antibodies, transport molecules and components of cell s ...
... The word protein was coined by Jons J. Berzselius, The famous Swedish chemist in 1838 and derived from the Greek work Proteios (meaning of the first rank). Proteins include several important cell constituents such as enzymes, peptide hormones, antibodies, transport molecules and components of cell s ...
Role of protein methylation in chromatin remodeling and
... post-translational histone modi®cation to regulate chromatin structure and gene transcription. Proteins that methylate histones on arginine residues can collaborate with other coactivators to enhance the activity of speci®c transcriptional activators such as nuclear receptors. Lysine methylation of ...
... post-translational histone modi®cation to regulate chromatin structure and gene transcription. Proteins that methylate histones on arginine residues can collaborate with other coactivators to enhance the activity of speci®c transcriptional activators such as nuclear receptors. Lysine methylation of ...
Biogenesis of the Protein Storage Vacuole Crystalloid
... (for DIP; Culianez-Macia and Martin, 1993) and are predominantly located in the cytoplasm. As seed development proceeds, these organelles are taken up by PSVs and aggregate such that they form the crystalloid in mature seeds. These organelles also represent an intermediate for vesicular traffic from ...
... (for DIP; Culianez-Macia and Martin, 1993) and are predominantly located in the cytoplasm. As seed development proceeds, these organelles are taken up by PSVs and aggregate such that they form the crystalloid in mature seeds. These organelles also represent an intermediate for vesicular traffic from ...
A system in mouse liver for the repair of O6
... Legend: These results are representative of many experiments performed with different mouse liver preparations. ...
... Legend: These results are representative of many experiments performed with different mouse liver preparations. ...
Caveolin-3 and SAP97 form a scaffolding protein complex that
... to hypothesize that SAP97 and Cav-3 form a scaffolding complex capable of recruiting Kv1.5 and regulating its function. We first carried out coimmunoprecipitation and pulldown experiments to test whether SAP97 and Cav-3 form a complex in the mouse heart. After SAP97 was immunoprecipitated from mouse ...
... to hypothesize that SAP97 and Cav-3 form a scaffolding complex capable of recruiting Kv1.5 and regulating its function. We first carried out coimmunoprecipitation and pulldown experiments to test whether SAP97 and Cav-3 form a complex in the mouse heart. After SAP97 was immunoprecipitated from mouse ...
Struct Bio 101
... "Within a single subunit [polypeptide chain], contiguous portions of the polypeptide chain frequently fold into compact, local semiindependent units called domains." - Richardson, 1981 Domains are: • can be built from structural motifs; • independently folding elements; • functional units; • separab ...
... "Within a single subunit [polypeptide chain], contiguous portions of the polypeptide chain frequently fold into compact, local semiindependent units called domains." - Richardson, 1981 Domains are: • can be built from structural motifs; • independently folding elements; • functional units; • separab ...
Localization of protein-binding sites within families of proteins
... PIBASE (Pieper et al. 2004; Davis and Sali 2005) and superposed them via a structural alignment of member structures. Next, we described the localization index of protein-binding sites and qualified it by three additional measures, including localization difference relative to a random localization, ...
... PIBASE (Pieper et al. 2004; Davis and Sali 2005) and superposed them via a structural alignment of member structures. Next, we described the localization index of protein-binding sites and qualified it by three additional measures, including localization difference relative to a random localization, ...
Poster
... Activation of the metabotropic GABAB receptor by GABA influences neuronal activity by coupling with G proteins to activate a signaling cascade that leads to downstream effects including the modulation of various ion channels. The GABAB receptor is a dimer composed of two different subunits (GBR1 and ...
... Activation of the metabotropic GABAB receptor by GABA influences neuronal activity by coupling with G proteins to activate a signaling cascade that leads to downstream effects including the modulation of various ion channels. The GABAB receptor is a dimer composed of two different subunits (GBR1 and ...
Biogenesis of the Protein Storage Vacuole Crystalloid
... (for DIP; Culianez-Macia and Martin, 1993) and are predominantly located in the cytoplasm. As seed development proceeds, these organelles are taken up by PSVs and aggregate such that they form the crystalloid in mature seeds. These organelles also represent an intermediate for vesicular traffic from ...
... (for DIP; Culianez-Macia and Martin, 1993) and are predominantly located in the cytoplasm. As seed development proceeds, these organelles are taken up by PSVs and aggregate such that they form the crystalloid in mature seeds. These organelles also represent an intermediate for vesicular traffic from ...
Perspectives
... ing Beadle and Tatum’s proposal of the one gene–one enzyme relationship, our understanding of the structural features of genes and enzymes was insufficient to allow formulation of a finite molecular relationship. Advances in the 1950s dealt with most of these issues and suggested a plausible experim ...
... ing Beadle and Tatum’s proposal of the one gene–one enzyme relationship, our understanding of the structural features of genes and enzymes was insufficient to allow formulation of a finite molecular relationship. Advances in the 1950s dealt with most of these issues and suggested a plausible experim ...
Cis-elements of protein transport to the plant vacuoles
... receptor-mediated accumulation in transport carrier vesicles. This model applies both to the lysosomal targeting by mannose-6-phosphate receptors and to the recycling of escaped ER-resident proteins. In the ER itself, sorting signals may contribute both to the specific concentration of secreted prot ...
... receptor-mediated accumulation in transport carrier vesicles. This model applies both to the lysosomal targeting by mannose-6-phosphate receptors and to the recycling of escaped ER-resident proteins. In the ER itself, sorting signals may contribute both to the specific concentration of secreted prot ...
Proteomic Analysis of Neisseria gonorrhoeae Biofilms
... making up the next largest group. Of the downregulated proteins, the largest groups were involved in protein synthesis and energy metabolism. These proteomics results were compared with our previously reported results from transcriptional profiling of gonococcal biofilms using microarrays. Nitrite r ...
... making up the next largest group. Of the downregulated proteins, the largest groups were involved in protein synthesis and energy metabolism. These proteomics results were compared with our previously reported results from transcriptional profiling of gonococcal biofilms using microarrays. Nitrite r ...
Mechanisms of Cellular injury
... • Increased susceptibility to respiratory infections, especially Staphylcoccus aureus, Pseudomonas and Burkholderi aeruginosa which are almost impossible to eliminate – Loss of ionic concentrations – Loss of antimicrobial peptide (defensin activity) – CFTR a receptor for Pseudomonas ...
... • Increased susceptibility to respiratory infections, especially Staphylcoccus aureus, Pseudomonas and Burkholderi aeruginosa which are almost impossible to eliminate – Loss of ionic concentrations – Loss of antimicrobial peptide (defensin activity) – CFTR a receptor for Pseudomonas ...
Principles of BIOCHEMISTRY
... • In prokaryotes, the 30S ribosome binds to a region of the mRNA (Shine-Dalgarno sequence) upstream of the initiation sequence • S-D sequence also binds to a complementary base sequence at the 3’ end of the 16S rRNA • Double-stranded RNA structure binds mRNA to the ribosome ...
... • In prokaryotes, the 30S ribosome binds to a region of the mRNA (Shine-Dalgarno sequence) upstream of the initiation sequence • S-D sequence also binds to a complementary base sequence at the 3’ end of the 16S rRNA • Double-stranded RNA structure binds mRNA to the ribosome ...
Telomerase Is a True Reverse Transcriptase
... who use retroviral reverse transcriptases as tools for copying RNA in the laboratory think of the enzyme as being only transiently associated with its RNA template, a number of reverse transcriptases are found as stable ribonucleoprotein complexes [29, 30]. Furthermore, even HIV reverse transcriptas ...
... who use retroviral reverse transcriptases as tools for copying RNA in the laboratory think of the enzyme as being only transiently associated with its RNA template, a number of reverse transcriptases are found as stable ribonucleoprotein complexes [29, 30]. Furthermore, even HIV reverse transcriptas ...
Protein performance in emulsion stability
... of bowl chopper or cutters allows a greater freedom to manipulate emulsion properties and characteristics. The use of this equipment allows for staged addition and varying the chopping time and speed in order to optimise quality. In a country like Germany known for its premium quality sausage, opera ...
... of bowl chopper or cutters allows a greater freedom to manipulate emulsion properties and characteristics. The use of this equipment allows for staged addition and varying the chopping time and speed in order to optimise quality. In a country like Germany known for its premium quality sausage, opera ...
metabolism of amino acids
... • Positive nitrogen balance- an excess of ingested over excreted nitrogen- during growth and pregnancy • Negative nitrogen balance – output exceeds intakeduring surgery, advanced cancer or malnutrition ...
... • Positive nitrogen balance- an excess of ingested over excreted nitrogen- during growth and pregnancy • Negative nitrogen balance – output exceeds intakeduring surgery, advanced cancer or malnutrition ...
Slow Protein Conformational Change, Allostery and
... consideration of the biochemical/biophysical properties of each composing macromolecule. One of the reasons that account for the current state of affair is due to a lack of experimental data and theoretical understanding in the "intermediate regime" between single-molecule studies of individual enzy ...
... consideration of the biochemical/biophysical properties of each composing macromolecule. One of the reasons that account for the current state of affair is due to a lack of experimental data and theoretical understanding in the "intermediate regime" between single-molecule studies of individual enzy ...
Affinity Chromatography
... the partner as a template on which to model a biomimetic ligand (40); second, construction of a molecule which displays complementarity to exposed residues in the target site (41–44); and third, direct mimicking of natural biological recognition interactions (45). Peptidal templates comprising two o ...
... the partner as a template on which to model a biomimetic ligand (40); second, construction of a molecule which displays complementarity to exposed residues in the target site (41–44); and third, direct mimicking of natural biological recognition interactions (45). Peptidal templates comprising two o ...
Amino Acids
... main-chain atoms of glycine are highlighted in yellow and its side chain (H) is highlighted in green. All amino acids have the same main-chain ...
... main-chain atoms of glycine are highlighted in yellow and its side chain (H) is highlighted in green. All amino acids have the same main-chain ...
Conclusion Presynaptic Neuron Postsynaptic Neuron
... neurotransmitters from nerve cells resulting in changes in synaptic transmission. Disorders result when levels of AEA and 2-AG are either too high or too low. While 2-AG is synthesized at the plasma membrane (PM) AEA is produced in the ER and may require an intracellular, carrier protein to move thr ...
... neurotransmitters from nerve cells resulting in changes in synaptic transmission. Disorders result when levels of AEA and 2-AG are either too high or too low. While 2-AG is synthesized at the plasma membrane (PM) AEA is produced in the ER and may require an intracellular, carrier protein to move thr ...
Protein–protein interaction
Protein–protein interactions (PPIs) refer to physical contacts established between two or more proteins as a result of biochemical events and/or electrostatic forces.In fact, proteins are vital macromolecules, at both cellular and systemic levels, but they rarely act alone. Diverse essential molecular processes within a cell are carried out by molecular machines that are built from a large number of protein components organized by their PPIs. Indeed, these interactions are at the core of the entire interactomics system of any living cell and so, unsurprisingly, aberrant PPIs are on the basis of multiple diseases, such as Creutzfeld-Jacob, Alzheimer's disease, and cancer.PPIs have been studied from different perspectives: biochemistry, quantum chemistry, molecular dynamics, signal transduction, among others. All this information enables the creation of large protein interaction networks – similar to metabolic or genetic/epigenetic networks – that empower the current knowledge on biochemical cascades and disease pathogenesis, as well as provide putative new therapeutic targets.