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WENJUN GUO, Ph.D.  Positions: Research interests:
WENJUN GUO, Ph.D. Positions: Research interests:

... important for breast cancer prevention and treatment. Distinct stem/progenitor cell populations have recently been identified in the mammary gland. It is likely that accumulation of genetic/epigenetic mutations in different cell types leads to distinct tumor subtypes. Thus we are elucidating the nor ...
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Polycomb Group Proteins and Cancer

The Polycomb-group proteins (PcGs) are a family of proteins that use epigenetic mechanisms to maintain or repress expression of their target genes. They were originally discovered in Drosophila (fruit flies), though they've been shown to be conserved in many species due to their vital roles in embryonic development. These proteins' ability to alter gene expression has made them targets of investigation for research groups seeking to understand disease pathology and oncology.
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