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Edges of Life
Edges of Life

... • Organisms become good at what they do: “adapted” to their environment & lifestyle • In many cases historical contingencies prevent “optimal” adaptation: “bad design” ...
Status and plans, human vs. mouse alignments
Status and plans, human vs. mouse alignments

... • Determine the biological role of each functional sequence • Elucidate the evolutionary history of each type of sequence • Provide bioinformatic tools so that anyone can easily incorporate insights from comparative genomics into their research ...
Print Name: UNR I.D. Number: BIOL 191 SPRING 2005 Midterm 1
Print Name: UNR I.D. Number: BIOL 191 SPRING 2005 Midterm 1

... heterogametic in birds and butterflies (ZW). (Note, students don’t need to include this latter statement but it could compensate partially for a poor definition (up to 2 points). ...
Document
Document

... Have focused on changes in bp sequence of genes. This can actually lead to changes in gene function if the bp sequence changes are nonsynonymous and result in changes in amino acids. But in course of evolution, more complex organisms have arisen with increased number of genes. Genes with old functio ...
Handout
Handout

... since the protein sequence is not changed. In contrast, the nonsynonymous substitutions are likely under selection. •  Ks: the number of synonymous substitutions per site Ka: the number of nonsynonymous substitutions per site •  Ka/Ks: indicator of selective constrains ...
Experimental Evolution and the Krogh Principle
Experimental Evolution and the Krogh Principle

... we use biological methodologies to create novel organisms ideally suited for particular physiological studies. Transgenics may first come to mind as the method for such transformations, but here I suggest that an alternative and complementary technique for generating biological novelty is experiment ...
Chapter 17-Human Evolution
Chapter 17-Human Evolution

... (2) The location of the foramen magnum indicates the angle at which the spinal cord exits the skull, a clear indicator of posture. (3) Fossil evidence of Neanderthals who met a violent death in areas where Cro-Magnons later flourished would constitute evidence that the Neanderthals were killed off b ...
Interaction in Metapopulations: Effects on Adaptation and Diversity
Interaction in Metapopulations: Effects on Adaptation and Diversity

... limited by the influx of genes with opposite effects from other demes. Second, if the genetic correlation is negative (Fig. 1 Upper), then G x E is a constraint when selection is uniform, i.e., the direction of selection is the same in all environments. With G x E and gene flow, selection favors ada ...
Lecture 9 - POSTED -BISC441-2012
Lecture 9 - POSTED -BISC441-2012

... (2) Studies of brain and language genes (3) Studies of food genes (lactase, amylase) (4) Studies of reproduction genes (5) Studies of disease-related genes ...
here
here

... You can determine omega for the whole dataset; however, usually not all sites in a sequence are under selection all the ...
Document
Document

... The theory of evolution by natural selection has been very successful, and has, in particular, stood up remarkably well against the findings of molecular biology and genetics.  Consistent with many experiments based on artificial selection (breeding), as Darwin noted.  Seems a natural successor to ...
Annotating ebony on the fly
Annotating ebony on the fly

... side-effects may offset otherwise adaptive changes in pigmentation genes. Mutations studied in the laboratory are not expected to capture the mutational spectrum found in the wild, and it is the latter that is needed to formulate hypotheses as to how evolution might progress. Considering what is kno ...
Types of Natural Selection
Types of Natural Selection

... with long tongues could more effectively prey on termites than those with short or average tongue length ...
Positive Darwinian Selection
Positive Darwinian Selection

... We note that the McDonald-Kreitman test requires data from many individuals from two populations or species. Let’s assume we only have one sequence from each species. ...
Evolution Lab Expectations: You will be working in groups of 2 to
Evolution Lab Expectations: You will be working in groups of 2 to

... After each on-line activity, complete the corresponding review activity. There are five review activities. Complete Post-Test upon completion of the 5 activities. Procedure w/ Blast (pages S44 to S48). Be sure to document a hypothesis (step 1 on page S45) Analyzing Data – for each of the 3 genes tha ...
Course Specifications
Course Specifications

... Case studies on population fragmentation, individual-based estimates, selection and evolution; ...
Bacteria are different: Observations, interpretations
Bacteria are different: Observations, interpretations

... sexual eukaryotes as well as bacteria, these compensatory mutations are likely to be the first to arise when, as is probable, there are more ways to improve fitness of the organism than mutation (reversion) at the deleterious locus. If recombination is common, however, these compensatory mutations a ...
Script 2
Script 2

... [33] more of them died before reproducing. But the small-beaked finches, which still had plenty of food, survived and had babies—which meant there were more genes for small beaks within the finch population. [34] Once again a change in gene frequency—or microevolution—had occurred in the finch popul ...
Topic 11 How Populations Evolve Objectives Darwin ` s Theory of
Topic 11 How Populations Evolve Objectives Darwin ` s Theory of

... Explain why individuals cannot evolve and why evolution does not lead to perfectly adapted organisms. Describe two examples of natural selection known to occur in nature. Note three key points about how natural selection works. Explain how fossils form, noting examples of each process. Explain how t ...
unnatural selection or artificial selection or selective breeding
unnatural selection or artificial selection or selective breeding

... Reproductive success is defined as the passing of genes into the next generation in a way that they too can pass on these genes. Organisms compete for food, water, space, and territory, sexual mates, (sexual selection) e.g. peacocks vs horned animals. They also compete in their resistance to disease ...
Diapositiva 1 - Curso de Sistemática IB 2010
Diapositiva 1 - Curso de Sistemática IB 2010

... Pseudogenes show an extremely high rate of nucleotide substitution. ...
Export To Word
Export To Word

... Founder Effect ...
Unit Plan Part 1
Unit Plan Part 1

... 1. Darwin’s theory of evolution  Describe Darwin’s contribution to science. 2. Evolution is a change in the relative  Identify indicators of evolution in a population. frequency of alleles in a population  Relate allele frequencies to gene pools by explaining what each term refers to and how they ...
BIOLOGY EOCT REVIEW SHEET GILES
BIOLOGY EOCT REVIEW SHEET GILES

... 6) Describe what happens in the four steps of DNA replication. 7) Why does DNA need to replicate itself? 8) Where does transcription happen? What happens during transcription? 9) Where does translation happen? What happens during translation? 10) What are the three types of RNA? What does each type ...
Print this article - PAGEPress Publications
Print this article - PAGEPress Publications

... fast running, feeding on insects, or the generation of commercially produced fruit that is popular with human consumers. These examples run counter to the general theme that there is a strong role for constraint in limiting the evolvability of species. On this last point, it has controversially been ...
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Adaptive evolution in the human genome

Adaptive evolution results from the propagation of advantageous mutations through positive selection. This is the modern synthesis of the process which Darwin and Wallace originally identified as the mechanism of evolution. However, in the last half century there has been considerable debate as to whether evolutionary changes at the molecular level are largely driven by natural selection or random genetic drift. Unsurprisingly, the forces which drive evolutionary changes in our own species’ lineage have been of particular interest. Quantifying adaptive evolution in the human genome gives insights into our own evolutionary history and helps to resolve this neutralist-selectionist debate. Identifying specific regions of the human genome that show evidence of adaptive evolution helps us find functionally significant genes, including genes important for human health, such as those associated with diseases.
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