Evidence-Based Pharmacological Treatment of Geriatric Bipolar Disorder Robert C. Young, MD *
... LI has been widely prescribed in the elderly [14,15]. Among communitybased BP patients from Western Pennsylvania in the late 1990s, close to two thirds of those over the age of 65 were treated with LI, and only 31% were receiving anticonvulsants; the proportion of older patients treated with LI was ...
... LI has been widely prescribed in the elderly [14,15]. Among communitybased BP patients from Western Pennsylvania in the late 1990s, close to two thirds of those over the age of 65 were treated with LI, and only 31% were receiving anticonvulsants; the proportion of older patients treated with LI was ...
Epidemiology of Idiopathic Pulmonary Fibrosis: The
... nintedanib. Monitor ALT, AST, and bilirubin before and during treatment. Temporary dosage reductions or discontinuations may be required. GI disorders: Diarrhea, nausea, and vomiting have occurred with nintedanib. Treat patients at first signs with adequate hydration and antidiarrheal medicine (e.g. ...
... nintedanib. Monitor ALT, AST, and bilirubin before and during treatment. Temporary dosage reductions or discontinuations may be required. GI disorders: Diarrhea, nausea, and vomiting have occurred with nintedanib. Treat patients at first signs with adequate hydration and antidiarrheal medicine (e.g. ...
Product Monograph - Paladin Labs Inc.
... whether Antizol can cause fetal harm when administered to pregnant women or can affect reproduction capacity. Antizol should be given to pregnant women only if clearly needed. ...
... whether Antizol can cause fetal harm when administered to pregnant women or can affect reproduction capacity. Antizol should be given to pregnant women only if clearly needed. ...
SLCO1B1 - PGXL Laboratories
... fold. Risk of myopathy with the *5 variant is most closely associated with simvastatin and to a lesser extent, atorvastatin. Patients with the *5 variant may need the lowest doses of simvastatin or an alternative statin to reduce risk of myopathy. SLC6A4 SLC6A4 is the gene that makes the serotonin t ...
... fold. Risk of myopathy with the *5 variant is most closely associated with simvastatin and to a lesser extent, atorvastatin. Patients with the *5 variant may need the lowest doses of simvastatin or an alternative statin to reduce risk of myopathy. SLC6A4 SLC6A4 is the gene that makes the serotonin t ...
LYRICA® Hard Capsule 75mg, 150mg, 300mg
... 2.3 Adjunctive therapy for adult patients with partial onset seizures LYRICA at doses of 150 to 600 mg/day has been shown to be effective as adjunctive therapy in the treatment of partial onset seizures in adults. Both the efficacy and adverse event profiles of LYRICA have been shown to be dose-rela ...
... 2.3 Adjunctive therapy for adult patients with partial onset seizures LYRICA at doses of 150 to 600 mg/day has been shown to be effective as adjunctive therapy in the treatment of partial onset seizures in adults. Both the efficacy and adverse event profiles of LYRICA have been shown to be dose-rela ...
Relenza inhalation powder pre
... been treated, it has not been possible to demonstrate the efficacy and safety of Relenza in these groups. Due to limited and inconclusive data, the efficacy of Relenza in the prevention of influenza in the nursing home setting has not been demonstrated. The efficacy of zanamivir for the treatment of ...
... been treated, it has not been possible to demonstrate the efficacy and safety of Relenza in these groups. Due to limited and inconclusive data, the efficacy of Relenza in the prevention of influenza in the nursing home setting has not been demonstrated. The efficacy of zanamivir for the treatment of ...
Trazodone (Desyrel)
... aggression in patients with Alzheimer’s disease and other brain disorders. Also, at low doses, trazodone has antianxiety effects and may be effective in treating generalized anxiety disorder. These uses for trazodone, however, are outside their indication; trazodone was approved only for the treatme ...
... aggression in patients with Alzheimer’s disease and other brain disorders. Also, at low doses, trazodone has antianxiety effects and may be effective in treating generalized anxiety disorder. These uses for trazodone, however, are outside their indication; trazodone was approved only for the treatme ...
morphine sulfate
... Nonteratogenic Effects: Narcotic analgesics cross the placental barrier; hence, newborn infants whose mothers have been administered such analgesics during labor should be closely observed for signs of respiratory depression and treated for narcotic overdosage if necessary. ADVERSE REACTIONS The maj ...
... Nonteratogenic Effects: Narcotic analgesics cross the placental barrier; hence, newborn infants whose mothers have been administered such analgesics during labor should be closely observed for signs of respiratory depression and treated for narcotic overdosage if necessary. ADVERSE REACTIONS The maj ...
FOI 204-1314 document 1 - Therapeutic Goods Administration (TGA)
... The mechanism of action of sertraline is presumed to be linked to its inhibition of CNS neuronal uptake of serotonin (5HT). Studies at clinically relevant doses in man have demonstrated that sertraline blocks the uptake of serotonin into human platelets. In vitro studies in animals also suggest that ...
... The mechanism of action of sertraline is presumed to be linked to its inhibition of CNS neuronal uptake of serotonin (5HT). Studies at clinically relevant doses in man have demonstrated that sertraline blocks the uptake of serotonin into human platelets. In vitro studies in animals also suggest that ...
Bacterial keratitis
... corneal biopsy – when an infection fails to resolve in spite of antimicrobial treatment initial treatment with concentrated antibiotic eyedrops is based on the result of Gram stain; after the isolation of te causative organism may indicate specific therapy. Gram – organisms are treated with aminogly ...
... corneal biopsy – when an infection fails to resolve in spite of antimicrobial treatment initial treatment with concentrated antibiotic eyedrops is based on the result of Gram stain; after the isolation of te causative organism may indicate specific therapy. Gram – organisms are treated with aminogly ...
P-RMS
... some statins. The risk of myopathy and rhabdomyolysis due to statins metabolised by CYP3A4 may be increased with concomitant use of diltiazem. When possible, a non CYP3A4-metabolised statin should be used together with diltiazem, otherwise close monitoring for signs and symptoms of a potential stati ...
... some statins. The risk of myopathy and rhabdomyolysis due to statins metabolised by CYP3A4 may be increased with concomitant use of diltiazem. When possible, a non CYP3A4-metabolised statin should be used together with diltiazem, otherwise close monitoring for signs and symptoms of a potential stati ...
Full Product Information
... development of increased iris pigmentation. Therefore, treatment with latanoprost can be continued in patients who develop increased iris pigmentation. These patients should be examined regularly and, depending on the clinical situation, treatment may be stopped. Onset of increased iris pigmentation ...
... development of increased iris pigmentation. Therefore, treatment with latanoprost can be continued in patients who develop increased iris pigmentation. These patients should be examined regularly and, depending on the clinical situation, treatment may be stopped. Onset of increased iris pigmentation ...
Atropine
... apparent volume of distribution (2 to 4 L/kg). It is metabolised in the liver to several metabolites and excreted mainly in the urine. Atropine has a plasma half-life of 2–3 hours. Following intramuscular administration, elimination appears to be biphasic with an initial phase of about 2 hours and a ...
... apparent volume of distribution (2 to 4 L/kg). It is metabolised in the liver to several metabolites and excreted mainly in the urine. Atropine has a plasma half-life of 2–3 hours. Following intramuscular administration, elimination appears to be biphasic with an initial phase of about 2 hours and a ...
Dabigatran versus Warfarin in Patients with Atrial Fibrillation
... lism in those treated with 150 mg of dabigratran twice daily. In this trial, the incidence of both thrombotic and hemorrhagic events in patients treated with warfarin far exceeds the incidence of these events in patients in the European Action on Anticoagulation (EAA) study1 (Table 1); the inci den ...
... lism in those treated with 150 mg of dabigratran twice daily. In this trial, the incidence of both thrombotic and hemorrhagic events in patients treated with warfarin far exceeds the incidence of these events in patients in the European Action on Anticoagulation (EAA) study1 (Table 1); the inci den ...
Top 300 Drug List
... Finish course as prescribed. Avoid ETOH and "hidden" ETOH during therapy and for 72 hours after. May discolor urine reddish-brown. Most likely can cause nausea, headache, dizziness and metallic taste. Take with food to decrease nausea. Monitor for peripheral neuropathy, seizure activity and mental s ...
... Finish course as prescribed. Avoid ETOH and "hidden" ETOH during therapy and for 72 hours after. May discolor urine reddish-brown. Most likely can cause nausea, headache, dizziness and metallic taste. Take with food to decrease nausea. Monitor for peripheral neuropathy, seizure activity and mental s ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
... rats, cats etc. The mechanism of the convulsant action of the PTZ seems to be related to the inhibition of the inhibitory function of the GABA neurotransmitter. PTZ is used for the screening of the absence seizures. 5 Seizures are adequately controlled with the presently available antiepileptic drug ...
... rats, cats etc. The mechanism of the convulsant action of the PTZ seems to be related to the inhibition of the inhibitory function of the GABA neurotransmitter. PTZ is used for the screening of the absence seizures. 5 Seizures are adequately controlled with the presently available antiepileptic drug ...
clavamox amoxicillin and clavulanate potassium tablets usp
... From animal studies there is no evidence for significant tissue retention of drug-derived material for either component. Amoxicillin,like most penicillins, can be detected in breast milk. Trace quantities of clavulanic acid can also be detected in breast milk. Both amoxicillin and clavulanic acid ha ...
... From animal studies there is no evidence for significant tissue retention of drug-derived material for either component. Amoxicillin,like most penicillins, can be detected in breast milk. Trace quantities of clavulanic acid can also be detected in breast milk. Both amoxicillin and clavulanic acid ha ...
Penicillin VK - The Main Line Center for the Family
... common to feel better early in the course of therapy, the medication should be taken exactly as directed. Skipping doses or not completing the full course of therapy may: (1) decrease the effectiveness of the immediate treatment, and (2) increase the likelihood that bacteria will develop resistance ...
... common to feel better early in the course of therapy, the medication should be taken exactly as directed. Skipping doses or not completing the full course of therapy may: (1) decrease the effectiveness of the immediate treatment, and (2) increase the likelihood that bacteria will develop resistance ...
A Parallel Phase I/II Clinical Trial Design for Combination Therapies
... Wei and Durham, 1978). A disadvantage of these approaches is that it does not account for the reliability of the estimated values of Pi . The difference between, say, Pi = 0.4 and Pj = 0.5 results in the same difference in assignment probabilities throughout the trial. Consequently, these designs are ...
... Wei and Durham, 1978). A disadvantage of these approaches is that it does not account for the reliability of the estimated values of Pi . The difference between, say, Pi = 0.4 and Pj = 0.5 results in the same difference in assignment probabilities throughout the trial. Consequently, these designs are ...
Methadone - Medicines Management
... sequestration, and it has a characteristically long half-life in plasma of around 24 hours (range 8-75 hours). Methadone is mainly metabolized in the liver to several inactive metabolites. It is then excreted via the intestines and kidneys. However renal and hepatic impairment do not significantly a ...
... sequestration, and it has a characteristically long half-life in plasma of around 24 hours (range 8-75 hours). Methadone is mainly metabolized in the liver to several inactive metabolites. It is then excreted via the intestines and kidneys. However renal and hepatic impairment do not significantly a ...
requip tablets
... Patients treated with REQUIP have reported falling asleep while engaged in activities of daily living, including driving or operating machinery, which sometimes resulted in accidents. Although many of these patients reported somnolence while on REQUIP, some perceived that they had no warning signs, ...
... Patients treated with REQUIP have reported falling asleep while engaged in activities of daily living, including driving or operating machinery, which sometimes resulted in accidents. Although many of these patients reported somnolence while on REQUIP, some perceived that they had no warning signs, ...
Calcium Channel Blockers 1997
... inhibitors have demonstrated greater clinical benefits.16 Adverse Effects Although generally well tolerated, CCBs side effect profiles differ according to class and dosage form. Older dihydropyridines (nifedipine, nicardipine) cause ...
... inhibitors have demonstrated greater clinical benefits.16 Adverse Effects Although generally well tolerated, CCBs side effect profiles differ according to class and dosage form. Older dihydropyridines (nifedipine, nicardipine) cause ...
Sitamet Tablet - Renata Limited
... Lactic acidosis: Lactic acidosis is a rare, but serious, metabolic complication that can occur due to metformin accumulation during treatment. Adverse reactions occurring in 3% of patients include diarrhoea, nausea, vomiting, abdominal bloating, flatulence, anorexia, unpleasant metallic taste. Drug ...
... Lactic acidosis: Lactic acidosis is a rare, but serious, metabolic complication that can occur due to metformin accumulation during treatment. Adverse reactions occurring in 3% of patients include diarrhoea, nausea, vomiting, abdominal bloating, flatulence, anorexia, unpleasant metallic taste. Drug ...
) PCH
... psoriasis, and adult rheumatoid arthritis, Methotrexate inhibits dihydrofolic acid reductase. Dihydrofolates must be reduced to tetrahydrofolates by this enzyme before they can be utilized as carriers of one-carbon groups in the synthesis of purine nucleotides and thymidylate. Therefore, methotrexat ...
... psoriasis, and adult rheumatoid arthritis, Methotrexate inhibits dihydrofolic acid reductase. Dihydrofolates must be reduced to tetrahydrofolates by this enzyme before they can be utilized as carriers of one-carbon groups in the synthesis of purine nucleotides and thymidylate. Therefore, methotrexat ...
AusPAR: Perampanel (as hemisesquihydrate)
... Antiepileptic drugs (AEDs) can often reduce the frequency and severity of seizures, producing lasting seizure-free intervals in some patients but up to 30% of patients with epilepsy are resistant to drug treatment and continue to have frequent seizures despite treatment. Most existing anticonvulsant ...
... Antiepileptic drugs (AEDs) can often reduce the frequency and severity of seizures, producing lasting seizure-free intervals in some patients but up to 30% of patients with epilepsy are resistant to drug treatment and continue to have frequent seizures despite treatment. Most existing anticonvulsant ...
Ofloxacin
Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.