Full Text - Int J Endocrinol Metab
... the vast majority of patients in this series (95.6%) received MMI. The majority of cases developed during the first few weeks of initiation of antithyroid therapy. Thionamideassociated agranulocytosis occurred irrespective of patient age and sex and duration of treatment. Low-dose methimazole seemed ...
... the vast majority of patients in this series (95.6%) received MMI. The majority of cases developed during the first few weeks of initiation of antithyroid therapy. Thionamideassociated agranulocytosis occurred irrespective of patient age and sex and duration of treatment. Low-dose methimazole seemed ...
XinpengBai (169
... oxidation of linoleic acid with both FTC and TBA methods, and the antioxidant activity of EEAD-Bu was highest among allextracts (p < 0.01). Furthermore, the results also demonstrate that this natural product contains antioxidant activity. Table 2 shows the activities of serum ALT and AST in differen ...
... oxidation of linoleic acid with both FTC and TBA methods, and the antioxidant activity of EEAD-Bu was highest among allextracts (p < 0.01). Furthermore, the results also demonstrate that this natural product contains antioxidant activity. Table 2 shows the activities of serum ALT and AST in differen ...
CELEBREX Cardiovascular Risk celecoxib capsules
... anti-inflammatory, analgesic, and antipyretic activities in animal models. The mechanism of action of CELEBREX is believed to be due to inhibition of prostaglandin synthesis, primarily via inhibition of cyclooxygenase-2 (COX-2), and at therapeutic concentrations in humans, CELEBREX does not inhibit ...
... anti-inflammatory, analgesic, and antipyretic activities in animal models. The mechanism of action of CELEBREX is believed to be due to inhibition of prostaglandin synthesis, primarily via inhibition of cyclooxygenase-2 (COX-2), and at therapeutic concentrations in humans, CELEBREX does not inhibit ...
Administration of eye preparations
... Bacterial blepharitis is treated with an antibacterial eye ointment or drops. Although most cases of acute bacterial conjunctivitis may resolve spontaneously, anti-infective treatment shortens the infectious process and prevents complications. Acute infective conjunctivitis is treated with antibacte ...
... Bacterial blepharitis is treated with an antibacterial eye ointment or drops. Although most cases of acute bacterial conjunctivitis may resolve spontaneously, anti-infective treatment shortens the infectious process and prevents complications. Acute infective conjunctivitis is treated with antibacte ...
Differin - Galderma
... For external use only. Avoid contact with the eyes, lips, angles of the nose, mucous membranes and open wounds. Certain cutaneous signs and symptoms such as erythema, dryness, scaling, burning or pruritus are associated with the topical application of retinoids and can also be expected with the use ...
... For external use only. Avoid contact with the eyes, lips, angles of the nose, mucous membranes and open wounds. Certain cutaneous signs and symptoms such as erythema, dryness, scaling, burning or pruritus are associated with the topical application of retinoids and can also be expected with the use ...
Fluoxetine Accord capsule, hard ENG SmPC
... (see section 5.1). Dosage adjustments should be made carefully on an individual patient basis, to maintain the patients at the lowest effective dose. Patients with depression should be treated for a sufficient period of at least 6 months to ensure that they are free from symptoms. Obsessive-compulsi ...
... (see section 5.1). Dosage adjustments should be made carefully on an individual patient basis, to maintain the patients at the lowest effective dose. Patients with depression should be treated for a sufficient period of at least 6 months to ensure that they are free from symptoms. Obsessive-compulsi ...
![phenytoin [see Drug Interactions (7)].](http://s1.studyres.com/store/data/000752461_1-e2f2c2eeaa79c174a4cc28c1e1447438-300x300.png)
phenytoin [see Drug Interactions (7)].
... interactions must be considered prior to and during therapy with KALETRA. Review of other medications taken by patients and monitoring of patients for adverse effects is recommended during therapy with KALETRA. See Tables 3 and 9 for listing of drugs that are contraindicated for use with KALETRA du ...
... interactions must be considered prior to and during therapy with KALETRA. Review of other medications taken by patients and monitoring of patients for adverse effects is recommended during therapy with KALETRA. See Tables 3 and 9 for listing of drugs that are contraindicated for use with KALETRA du ...
Australian Public Assessment Report for Fampridine
... data compiled by Judge and Bever (2006) showed a wide range of values (647-13,000 µM), with the sponsor-determined value just outside this range. The data from Gutman et al. (2005)/IUPHAR and Judge and Bever (2006) reveal that fampridine is a broad spectrum potassium channel blocker, inhibiting a nu ...
... data compiled by Judge and Bever (2006) showed a wide range of values (647-13,000 µM), with the sponsor-determined value just outside this range. The data from Gutman et al. (2005)/IUPHAR and Judge and Bever (2006) reveal that fampridine is a broad spectrum potassium channel blocker, inhibiting a nu ...
product monograph
... occupying positions 25 to 33 varies among species and it is this part of the molecule which is most antigenic when ACTH of foreign origin is administered to man. In contrast, the N-terminal 24 amino-acid sequence is common to all species and is relatively non-antigenic, and it is only these amino-ac ...
... occupying positions 25 to 33 varies among species and it is this part of the molecule which is most antigenic when ACTH of foreign origin is administered to man. In contrast, the N-terminal 24 amino-acid sequence is common to all species and is relatively non-antigenic, and it is only these amino-ac ...
March 2016
... response (HiSCR) which was defined as a greater than or equal to 50% decrease from baseline in inflammatory abscesses and nodules and no increase in the numbers of abscesses or draining fistulae. The PBAC noted that the pooled result from all three trials indicated that for every 100 patients treate ...
... response (HiSCR) which was defined as a greater than or equal to 50% decrease from baseline in inflammatory abscesses and nodules and no increase in the numbers of abscesses or draining fistulae. The PBAC noted that the pooled result from all three trials indicated that for every 100 patients treate ...
PegIntron - Merck.com
... The recommended dose of REBETOL for use with PegIntron is 800 to 1400 mg orally based on patient body weight. REBETOL should be taken with food. REBETOL should not be used in patients with creatinine clearance less than 50 mL/min. See labeling of the specific HCV NS3/4A protease inhibitor for inform ...
... The recommended dose of REBETOL for use with PegIntron is 800 to 1400 mg orally based on patient body weight. REBETOL should be taken with food. REBETOL should not be used in patients with creatinine clearance less than 50 mL/min. See labeling of the specific HCV NS3/4A protease inhibitor for inform ...
Slides - Clinical Trial Results
... • Cerebrovascular accident (CVA) • Re-infarction • Unplanned target lesion revascularisation (TLR) ...
... • Cerebrovascular accident (CVA) • Re-infarction • Unplanned target lesion revascularisation (TLR) ...
TRETN MEDICINES INFORMATION CENTRE
... Patches containing buprenorphine (Transtec®, Butrans®) are an alternative to oral opioid analgesics. The two brands are not interchangeable as they deliver different amounts of buprenorphine (Butrans is the weaker) and the time each patch is applied is different – 7 days for Butrans® and 4 days for ...
... Patches containing buprenorphine (Transtec®, Butrans®) are an alternative to oral opioid analgesics. The two brands are not interchangeable as they deliver different amounts of buprenorphine (Butrans is the weaker) and the time each patch is applied is different – 7 days for Butrans® and 4 days for ...
PRODUCT INFORMATION ZOLOFT (sertraline hydrochloride) NAME OF THE MEDICINE
... emerged, but OCD symptoms were worsened by meta-chlorophenylpiperazine (mCPP), a mixed agonist at serotonin receptors in untreated OCD patients in comparison to healthy controls, but not after patients had been treated with the non-selective 5HT reuptake inhibitor clomipramine. Tricyclic antidepress ...
... emerged, but OCD symptoms were worsened by meta-chlorophenylpiperazine (mCPP), a mixed agonist at serotonin receptors in untreated OCD patients in comparison to healthy controls, but not after patients had been treated with the non-selective 5HT reuptake inhibitor clomipramine. Tricyclic antidepress ...
1158-1161 Lovelyn Joseph 317 - International Journal of Bioassays
... over the world licensing them as dietary supplements without enough toxicological and interaction analysis data, there was drastic increase in use of herbal preparations which raise concern about their toxic and interactive propensity. This study analyzes the interaction of Valeriana wallichii (Indi ...
... over the world licensing them as dietary supplements without enough toxicological and interaction analysis data, there was drastic increase in use of herbal preparations which raise concern about their toxic and interactive propensity. This study analyzes the interaction of Valeriana wallichii (Indi ...
44 la. , F lle
... If a classic-looking bacterial ulcer isn’t responding to fluoroquinolones, when is it reasonable to suspect antibiotic resistance, in particular, methicillin-resistant Staphylococcus aureus (MRSA)? MRSA should be considered if a patient develops infectious keratitis in a hospital or nursing home, is ...
... If a classic-looking bacterial ulcer isn’t responding to fluoroquinolones, when is it reasonable to suspect antibiotic resistance, in particular, methicillin-resistant Staphylococcus aureus (MRSA)? MRSA should be considered if a patient develops infectious keratitis in a hospital or nursing home, is ...
Efficacy and safety of a 12-week course of therapy with a new
... Fluticasone distinguishes itself from other inhaled glycocorticosteroids by its high affinity with intracellular glycocorticosteroid receptor (18 times higher than dexamethasone), and its high lipophilic nature, which results in strong and long-lasting activity of the drug in the bronchi. Simultaneo ...
... Fluticasone distinguishes itself from other inhaled glycocorticosteroids by its high affinity with intracellular glycocorticosteroid receptor (18 times higher than dexamethasone), and its high lipophilic nature, which results in strong and long-lasting activity of the drug in the bronchi. Simultaneo ...
Antidepressant Drugs - Vendor Drug Program
... severe depression, treatment-resistant depression (TRD), and moderate anxiety/agitation/depression. Maximum recommended daily doses for antidepressant drugs in adults, including the elderly population, are summarized in Tables 1 and 2. Maximum recommended dosages for antidepressant combination thera ...
... severe depression, treatment-resistant depression (TRD), and moderate anxiety/agitation/depression. Maximum recommended daily doses for antidepressant drugs in adults, including the elderly population, are summarized in Tables 1 and 2. Maximum recommended dosages for antidepressant combination thera ...
Update and trends on pharmacokinetic studies in patients
... and simulation techniques may be useful to guide dosing recommendations in the target population with comorbid renal impairment. Common modeling and simulation methods can be broadly classified as top-down or bottom-up methods. Top-down methods rely on modeling of some available data, whereas bottom ...
... and simulation techniques may be useful to guide dosing recommendations in the target population with comorbid renal impairment. Common modeling and simulation methods can be broadly classified as top-down or bottom-up methods. Top-down methods rely on modeling of some available data, whereas bottom ...
Seretide PI - GSK Australia
... salmeterol xinafoate is slow (mean t½ is 67 hours). Excretion is predominantly through the faeces and to a lesser extent urine. Aliphatic hydroxylation appears to be the major route of metabolism in humans. After regular dosing with salmeterol xinafoate, the xinafoate moiety, hydroxynaphthoic acid, ...
... salmeterol xinafoate is slow (mean t½ is 67 hours). Excretion is predominantly through the faeces and to a lesser extent urine. Aliphatic hydroxylation appears to be the major route of metabolism in humans. After regular dosing with salmeterol xinafoate, the xinafoate moiety, hydroxynaphthoic acid, ...
PDF - Glaucoma Today
... crossed the placenta and entered into the fetal circulation to a limited extent. There are no adequate and well-controlled studies in pregnant women. SIMBRINZA® Suspension should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Nursing Mothers - In a ...
... crossed the placenta and entered into the fetal circulation to a limited extent. There are no adequate and well-controlled studies in pregnant women. SIMBRINZA® Suspension should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Nursing Mothers - In a ...
CH3 N N CF3 S NH O O
... CELEBRA has demonstrated significant reduction in joint tenderness/pain and joint swelling compared to placebo. CELEBRA was evaluated for treatment of the signs and symptoms of RA in approximately 2,100 patients in placebo- and active-controlled clinical trials of up to 24 weeks in duration. CELEBRA ...
... CELEBRA has demonstrated significant reduction in joint tenderness/pain and joint swelling compared to placebo. CELEBRA was evaluated for treatment of the signs and symptoms of RA in approximately 2,100 patients in placebo- and active-controlled clinical trials of up to 24 weeks in duration. CELEBRA ...
Liver Enzymes and Bilirubin Levels During
... ttention Deficit Hyperactivity Disorder (ADHD) is the most common psychiatric disorder among children and adolescents. Atomoxetine is the first non stimulant medication that has been FDA approved for the treatment of ADHD. Several placebo-controlled trials showed good efficacy and tolerability of at ...
... ttention Deficit Hyperactivity Disorder (ADHD) is the most common psychiatric disorder among children and adolescents. Atomoxetine is the first non stimulant medication that has been FDA approved for the treatment of ADHD. Several placebo-controlled trials showed good efficacy and tolerability of at ...
Pregnancy
... they do not point to an increased risk of congenital defects. Experience with the use of sumatriptan in the second and third trimester is limited. Evaluation of experimental animal studies does not indicate direct teratogenic effects or harmful effects on peri-and postnatal development. However, emb ...
... they do not point to an increased risk of congenital defects. Experience with the use of sumatriptan in the second and third trimester is limited. Evaluation of experimental animal studies does not indicate direct teratogenic effects or harmful effects on peri-and postnatal development. However, emb ...
DRUG NAME: Sorafenib
... Fertility: Animal studies indicate that sorafenib may impair male and female fertility. ...
... Fertility: Animal studies indicate that sorafenib may impair male and female fertility. ...
Ofloxacin
Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.