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HIGHLIGHTS OF PRESCRIBING INFORMATION These
... diabetes, in patients with diabetic nerve disease, in patients using medications that block the sympathetic nervous system (e.g., beta-blockers) [see Drug Interactions (7)], or in patients who experience recurrent hypoglycemia. Risk Factors for Hypoglycemia The risk of hypoglycemia after an injectio ...
... diabetes, in patients with diabetic nerve disease, in patients using medications that block the sympathetic nervous system (e.g., beta-blockers) [see Drug Interactions (7)], or in patients who experience recurrent hypoglycemia. Risk Factors for Hypoglycemia The risk of hypoglycemia after an injectio ...
zoloft - Medsafe
... the generally lower body weights of children compared to those of adults should be taken into consideration in advancing the dose from 50 mg, in order to avoid excessive dosing. The efficacy of sertraline in children with depression or panic disorder has not been demonstrated in controlled trials. S ...
... the generally lower body weights of children compared to those of adults should be taken into consideration in advancing the dose from 50 mg, in order to avoid excessive dosing. The efficacy of sertraline in children with depression or panic disorder has not been demonstrated in controlled trials. S ...
Product Monograph Template - Standard
... During inhalation, children should be assisted or supervised by an adult who knows the proper use of the device. Rarely, in children, hyperactivity occurs and occasionally, sleep disturbances, hallucination or atypical psychosis have been reported. Pediatrics (< 4 years of age): The safety and effic ...
... During inhalation, children should be assisted or supervised by an adult who knows the proper use of the device. Rarely, in children, hyperactivity occurs and occasionally, sleep disturbances, hallucination or atypical psychosis have been reported. Pediatrics (< 4 years of age): The safety and effic ...
Symbyax - Eli Lilly and Company
... Hyperprolactinemia: May elevate prolactin levels (5.21) Long Elimination Half-Life of Fluoxetine: Changes in dose will not be fully reflected in plasma for several weeks (5.23) ...
... Hyperprolactinemia: May elevate prolactin levels (5.21) Long Elimination Half-Life of Fluoxetine: Changes in dose will not be fully reflected in plasma for several weeks (5.23) ...
PDF Edition - Review of Ophthalmology
... senior management teams of both companies, with integration planning to begin immediately in order to transition rapidly to a single company. The combined company will provide a strong commitment to R&D, with an annual investment of approximately $1.7 billion, focused on the strategic development of ...
... senior management teams of both companies, with integration planning to begin immediately in order to transition rapidly to a single company. The combined company will provide a strong commitment to R&D, with an annual investment of approximately $1.7 billion, focused on the strategic development of ...
Effects of ciclesonide and fluticasone on cortisol secretion in patients with
... prescribing [9]. ...
... prescribing [9]. ...
Thiazide and Thiazide
... •is a thiazide like drug • It is primarily used to treat congestive hear failure and HTN • Metolazone indirectly decreases the amount of water reabsorbed into the bloodstream by the kidney, so that blood volume decreases and urine volume increases. This lowers blood pressure and prevents excess flui ...
... •is a thiazide like drug • It is primarily used to treat congestive hear failure and HTN • Metolazone indirectly decreases the amount of water reabsorbed into the bloodstream by the kidney, so that blood volume decreases and urine volume increases. This lowers blood pressure and prevents excess flui ...
Atrovent® HFA - Boehringer Ingelheim
... There is potential for an additive interaction with concomitantly used anticholinergic medications. Therefore, avoid coadministration of ATROVENT HFA with other anticholinergic-containing drugs as this may lead to an increase in anticholinergic adverse effects [see Warnings and Precautions (5.4, 5.5 ...
... There is potential for an additive interaction with concomitantly used anticholinergic medications. Therefore, avoid coadministration of ATROVENT HFA with other anticholinergic-containing drugs as this may lead to an increase in anticholinergic adverse effects [see Warnings and Precautions (5.4, 5.5 ...
Compare and Contrast: IBS/IBD
... Restricted Use/Precautions • Adverse effects (dose related) – Constipation – GI discomfort/pain ...
... Restricted Use/Precautions • Adverse effects (dose related) – Constipation – GI discomfort/pain ...
Salmeson Inhalation powder pre
... Clinically significant effects were not seen on blood pressure, heart rate, blood glucose and blood potassium levels. Co-administration with ketoconazole did not increase the elimination half-life of salmeterol or increase salmeterol accumulation with repeat dosing. The concomitant administration of ...
... Clinically significant effects were not seen on blood pressure, heart rate, blood glucose and blood potassium levels. Co-administration with ketoconazole did not increase the elimination half-life of salmeterol or increase salmeterol accumulation with repeat dosing. The concomitant administration of ...
PERCOCET - Endo Pharmaceuticals
... A high portion of oxycodone is N-dealkylated to noroxycodone during first-pass metabolism. Oxymorphone, is formed by the O-demethylation of oxycodone. The metabolism of oxycodone to oxymorphone is catalyzed by CYP2D6. Free and conjugated noroxycodone, free and conjugated oxycodone, and oxymorphone a ...
... A high portion of oxycodone is N-dealkylated to noroxycodone during first-pass metabolism. Oxymorphone, is formed by the O-demethylation of oxycodone. The metabolism of oxycodone to oxymorphone is catalyzed by CYP2D6. Free and conjugated noroxycodone, free and conjugated oxycodone, and oxymorphone a ...
Drug Information Letter New Drug Evaluation Multaq (dronedarone) Tablets
... ocular effects in the dronedarone group. The main gastrointestinal adverse effects were driven by a higher non-serious diarrheal occurrence in the dronedarone group (9.2%) versus the amiodarone group (3.1%). ...
... ocular effects in the dronedarone group. The main gastrointestinal adverse effects were driven by a higher non-serious diarrheal occurrence in the dronedarone group (9.2%) versus the amiodarone group (3.1%). ...
Calcium-Channel Blocker–Clarithromycin Drug Interactions and
... (CYP3A4; EC 1.14.13.97) enzyme. Blood concentrations of these drugs may rise to harmful levels when CYP3A4 activity is inhibited. Clarithromycin is an inhibitor of CYP3A4 and azithromycin is not, which makes comparisons between these 2 macrolide antibiotics useful in assessing clinically important d ...
... (CYP3A4; EC 1.14.13.97) enzyme. Blood concentrations of these drugs may rise to harmful levels when CYP3A4 activity is inhibited. Clarithromycin is an inhibitor of CYP3A4 and azithromycin is not, which makes comparisons between these 2 macrolide antibiotics useful in assessing clinically important d ...
Pravachol
... PRAVACHOL tablets. Approximately 50% of the circulating drug is bound to plasma proteins. The plasma elimination half-life (T1/2) of pravastatin (oral) is between 1.5 and 2 hours. Approximately 20% of a radio labelled oral dose is excreted in urine and 70% in the faeces. After intravenous administra ...
... PRAVACHOL tablets. Approximately 50% of the circulating drug is bound to plasma proteins. The plasma elimination half-life (T1/2) of pravastatin (oral) is between 1.5 and 2 hours. Approximately 20% of a radio labelled oral dose is excreted in urine and 70% in the faeces. After intravenous administra ...
Adverse Effects Of Herbs And Drug-Herbal Interactions
... Negara – personal communication). The most common adverse effects reported are hepatic and renal problems. However, it is difficult to identify the causative agent associated with the adverse reactions encountered because traditional herbal preparations often contain multiple ingredients. The above ...
... Negara – personal communication). The most common adverse effects reported are hepatic and renal problems. However, it is difficult to identify the causative agent associated with the adverse reactions encountered because traditional herbal preparations often contain multiple ingredients. The above ...
Asthma - The Rx Consultant
... tion is recommended for all asthma patients except those with mild intermittent disease. Patients with mild intermittent asthma have symptoms no more frequently than twice a week and nocturnal symptoms up to twice a month. If symptoms occur more than twice a week but less than daily, or nocturnal s ...
... tion is recommended for all asthma patients except those with mild intermittent disease. Patients with mild intermittent asthma have symptoms no more frequently than twice a week and nocturnal symptoms up to twice a month. If symptoms occur more than twice a week but less than daily, or nocturnal s ...
FIG 7: gingival index
... The serious toxic effects are uncommon; however, neurotoxic effects, such as vertigo, ataxy and leucopenia are reported. In general, short–duration therapies with metronidazole are well tolerated; however, some side effects which are completely reversible to the drug suspension might occur. The assu ...
... The serious toxic effects are uncommon; however, neurotoxic effects, such as vertigo, ataxy and leucopenia are reported. In general, short–duration therapies with metronidazole are well tolerated; however, some side effects which are completely reversible to the drug suspension might occur. The assu ...
1
... Fluvoxamine: May increase olanzapine levels; a lower dose of the olanzapine component of SYMBYAX should be considered (7.6) Drugs that Interfere with Hemostasis: (e.g., NSAIDs, Aspirin, Warfarin, etc.): May potentiate the risk of bleeding (7.4) Drugs Tightly Bound to Plasma Proteins: Fluoxetine may ...
... Fluvoxamine: May increase olanzapine levels; a lower dose of the olanzapine component of SYMBYAX should be considered (7.6) Drugs that Interfere with Hemostasis: (e.g., NSAIDs, Aspirin, Warfarin, etc.): May potentiate the risk of bleeding (7.4) Drugs Tightly Bound to Plasma Proteins: Fluoxetine may ...
Candesartan Aspen
... In hypertension, candesartan causes a dose-dependent, long-lasting reduction in arterial blood pressure. The antihypertensive action is due to decreased systemic peripheral resistance, while heart rate, stroke volume and cardiac output are not affected. There is no indication of serious or exaggerat ...
... In hypertension, candesartan causes a dose-dependent, long-lasting reduction in arterial blood pressure. The antihypertensive action is due to decreased systemic peripheral resistance, while heart rate, stroke volume and cardiac output are not affected. There is no indication of serious or exaggerat ...
Intravenous Anaesthesia
... • 20/123 (16%) patients had previous or existing hepatic disease (minimal – severe) • 5/123 (4%) patients had severe renal impairment (creatinine clearance 11-36 mL/min) • Adverse event rates were similar to overall population – Treatment-related AEs were similar to other patients (paresthesia 50%, ...
... • 20/123 (16%) patients had previous or existing hepatic disease (minimal – severe) • 5/123 (4%) patients had severe renal impairment (creatinine clearance 11-36 mL/min) • Adverse event rates were similar to overall population – Treatment-related AEs were similar to other patients (paresthesia 50%, ...
Clinical Actions of Specific Agents
... -Changes in liver function, plasma protein binding, blood volume and other important physiological functions influence the manner in which local anesthetics are distributed and biotransformed in the body -The half lives of amide local anesthetics are increased in the presence of decreased liver func ...
... -Changes in liver function, plasma protein binding, blood volume and other important physiological functions influence the manner in which local anesthetics are distributed and biotransformed in the body -The half lives of amide local anesthetics are increased in the presence of decreased liver func ...
Ketofol_in_the_ED
... • Lower mean propofol dose with ketofol (92.5mg vs 177.27mg) • No respiratory depression in either group ...
... • Lower mean propofol dose with ketofol (92.5mg vs 177.27mg) • No respiratory depression in either group ...
Morphine Sulphate Data sheet May 14
... dosage is escalated substantially above recommended levels because of tolerance development, convulsions may occur in individuals without a history of convulsive disorders. ...
... dosage is escalated substantially above recommended levels because of tolerance development, convulsions may occur in individuals without a history of convulsive disorders. ...
Antifungals and their use in veterinary ophthalmology - GEAC-UFV
... absorption of AMB is minimal; therefore, parenteral administration is recommended [41]. After intravenous administration, AMB is highly protein bound and redistributes from the blood to the tissues; however, central nervous system (CNS) penetration is poor. Less toxic formulations of AMB and nystati ...
... absorption of AMB is minimal; therefore, parenteral administration is recommended [41]. After intravenous administration, AMB is highly protein bound and redistributes from the blood to the tissues; however, central nervous system (CNS) penetration is poor. Less toxic formulations of AMB and nystati ...
acris combi
... concentration (Cavg) for 35 mg/week and 5 mg/day was not statistically significantly different. The 95% confidence interval for Cavg was 57.1-101.2, with a point estimate of 76.0% for the 35 mg dose compared to the 5 mg dose. Steady-state conditions in the serum are observed within 57 days of daily ...
... concentration (Cavg) for 35 mg/week and 5 mg/day was not statistically significantly different. The 95% confidence interval for Cavg was 57.1-101.2, with a point estimate of 76.0% for the 35 mg dose compared to the 5 mg dose. Steady-state conditions in the serum are observed within 57 days of daily ...
Ofloxacin
Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.