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PRESCRIBING INFORMATION AND CONSUMER
... Animal studies do not indicate direct or indirect harmful effects with respect to reproductive toxicity. There is insufficient information on the excretion of hyoscine butylbromide and its metabolites in human milk. As a precautionary measure, it is preferable to avoid the use of hyoscine butylbromi ...
... Animal studies do not indicate direct or indirect harmful effects with respect to reproductive toxicity. There is insufficient information on the excretion of hyoscine butylbromide and its metabolites in human milk. As a precautionary measure, it is preferable to avoid the use of hyoscine butylbromi ...
PRODUCT MONOGRAPH
... 100 mg/kg/day, and no evidence of harm to the fetus was observed in rats and rabbits at doses up to 300 mg/kg/day and 40 mg/kg/day, respectively. These doses are approximately 100, 300, and 40 times that which would result from a person ingesting 30 mL (2 capfuls) of PERICHLOR (0.12% chlorhexidine g ...
... 100 mg/kg/day, and no evidence of harm to the fetus was observed in rats and rabbits at doses up to 300 mg/kg/day and 40 mg/kg/day, respectively. These doses are approximately 100, 300, and 40 times that which would result from a person ingesting 30 mL (2 capfuls) of PERICHLOR (0.12% chlorhexidine g ...
HIGHLIGHTS OF PRESCRIBING INFORMATION --------------------------WARNINGS AND PRECAUTIONS---------------------------
... years, mean weight loss from baseline to endpoint was -2.7, -4.3, and -4.8 lbs., respectively, for patients receiving 30 mg, 50 mg, and 70 mg of Vyvanse, compared to a 2.0 pound weight gain for patients receiving placebo. Careful follow-up of weight and height in children ages 7 to 10 years who were ...
... years, mean weight loss from baseline to endpoint was -2.7, -4.3, and -4.8 lbs., respectively, for patients receiving 30 mg, 50 mg, and 70 mg of Vyvanse, compared to a 2.0 pound weight gain for patients receiving placebo. Careful follow-up of weight and height in children ages 7 to 10 years who were ...
Effects on upper gastrointestinal motility
... Metoclopramide influences various aspects of the motility of the upper digestive tract. The pressure in the lower esophageal sphincter is increased after intravenous or oral administration of the drug (3,4), the magnitude of the effect being dose-dependent, directly proportional to the basal pressur ...
... Metoclopramide influences various aspects of the motility of the upper digestive tract. The pressure in the lower esophageal sphincter is increased after intravenous or oral administration of the drug (3,4), the magnitude of the effect being dose-dependent, directly proportional to the basal pressur ...
Percocet® (oxycodone hydrochloride 5 mg / acetaminophen 325 mg)
... PERCOCET (oxycodone hydrochloride and acetaminophen) is indicated for relief of moderate to moderately severe pain, including conditions accompanied by fever. PERCOCET is not indicated as an as-needed (prn) analgesic. Geriatrics (> 65 years of age) In general, dose selection for an elderly patient s ...
... PERCOCET (oxycodone hydrochloride and acetaminophen) is indicated for relief of moderate to moderately severe pain, including conditions accompanied by fever. PERCOCET is not indicated as an as-needed (prn) analgesic. Geriatrics (> 65 years of age) In general, dose selection for an elderly patient s ...
High plasma linezolid concentration and impaired renal function
... P¼0.039). Although these studies were not aimed at investigating plasma linezolid concentrations, their data regarding the possible association between thrombocytopenia and renal insufficiency were in agreement with our study results. Brier et al.22 demonstrated that renal function had little effect ...
... P¼0.039). Although these studies were not aimed at investigating plasma linezolid concentrations, their data regarding the possible association between thrombocytopenia and renal insufficiency were in agreement with our study results. Brier et al.22 demonstrated that renal function had little effect ...
Adenosine
... Repeat administration: If conversion of PSVT does not occur within 1-2 minutes, additional bolus injections of adenosine can be administered at incrementally higher doses, increasing the amount given by 0.05 to 0.1 mg/kg. Follow each bolus with a saline flush. This process should continue until sinu ...
... Repeat administration: If conversion of PSVT does not occur within 1-2 minutes, additional bolus injections of adenosine can be administered at incrementally higher doses, increasing the amount given by 0.05 to 0.1 mg/kg. Follow each bolus with a saline flush. This process should continue until sinu ...
Product Monograph Template - Standard
... or threatened death or serious injury, or threat to the physical integrity of self or others, and a response which involves intense fear, helplessness, or horror. Symptoms that occur as a result of exposure to the traumatic event include reexperiencing of the event in the form of intrusive thoughts, ...
... or threatened death or serious injury, or threat to the physical integrity of self or others, and a response which involves intense fear, helplessness, or horror. Symptoms that occur as a result of exposure to the traumatic event include reexperiencing of the event in the form of intrusive thoughts, ...
highlights of prescribing information
... Embryofetal Toxicity (Use with Ribavirin and Peginterferon Alfa) Ribavirin may cause birth defects and/or death of the exposed fetus. Extreme care must be taken to avoid pregnancy in female patients and in female partners of male patients. Ribavirin therapy should not be started unless a report of a ...
... Embryofetal Toxicity (Use with Ribavirin and Peginterferon Alfa) Ribavirin may cause birth defects and/or death of the exposed fetus. Extreme care must be taken to avoid pregnancy in female patients and in female partners of male patients. Ribavirin therapy should not be started unless a report of a ...
Product Monograph Template - Standard - GlaxoSmithKline
... Although systemic effects have been minimal with recommended doses of FLONASE® aqueous nasal spray, potential risk increases with larger doses. Therefore, larger than recommended doses of FLONASE® aqueous nasal spray should be avoided. When intranasal steroids are used at higher than recommended dos ...
... Although systemic effects have been minimal with recommended doses of FLONASE® aqueous nasal spray, potential risk increases with larger doses. Therefore, larger than recommended doses of FLONASE® aqueous nasal spray should be avoided. When intranasal steroids are used at higher than recommended dos ...
AusPAR: Pitavastatin - Therapeutic Goods Administration
... muscle cells and hepatocytes with IC50s of 5.8, 3.4 and 24.5nM, respectively. The IC50 ratio of 1/3/6 obtained for pitavastatin, simvastatin and atorvastatin in HepG2 cells is close to the respective clinical dose ratios of 2 mg/5 mg/10 mg. In guinea pig livers, the 50% effective doses (ED50s) for i ...
... muscle cells and hepatocytes with IC50s of 5.8, 3.4 and 24.5nM, respectively. The IC50 ratio of 1/3/6 obtained for pitavastatin, simvastatin and atorvastatin in HepG2 cells is close to the respective clinical dose ratios of 2 mg/5 mg/10 mg. In guinea pig livers, the 50% effective doses (ED50s) for i ...
Gentak® (gentamicin sulfate ophthalmic ointment, USP) 0.3
... infections, including conjunctivitis, keratitis, keratoconjunctivitis, corneal ulcers, blepharitis, blepharoconjunctivitis, acute meibomianitis, and dacryocystitis caused by susceptible strains of the following microorganisms: Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes ...
... infections, including conjunctivitis, keratitis, keratoconjunctivitis, corneal ulcers, blepharitis, blepharoconjunctivitis, acute meibomianitis, and dacryocystitis caused by susceptible strains of the following microorganisms: Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes ...
Journal of Science Chemistry IMPACT OF GIVING SILDENAFIL
... disaggregatory actions of SNP both in vitro and ex vivo. The consequences of this antiplatelet action have been investigated. There was a trend to increased bleeding time in rat (60% increase not statistically significant, after 0.3 mg/kg i.v.) and bleeding time prolongation was seen in rabbits (129 ...
... disaggregatory actions of SNP both in vitro and ex vivo. The consequences of this antiplatelet action have been investigated. There was a trend to increased bleeding time in rat (60% increase not statistically significant, after 0.3 mg/kg i.v.) and bleeding time prolongation was seen in rabbits (129 ...
The Use of Midazolam in Paediatric Dentistry: A Review of the
... of child patients reported that the technique was well tolerated by children and their parents. However, some children became upset in recovery due to the numb sensation of their lip caused by local anaesthtics. Oral midazolam sedation was mentioned to be safe and effective although some patients be ...
... of child patients reported that the technique was well tolerated by children and their parents. However, some children became upset in recovery due to the numb sensation of their lip caused by local anaesthtics. Oral midazolam sedation was mentioned to be safe and effective although some patients be ...
View Prescribing Details
... other alpha-adrenergic blocking agents have not been determined. However, interactions may be expected and Maxflo-U® should not be used in combination with other alpha-adrenergic blocking agents. Warning The signs and symptoms of orthostasis (postural hypotension, dizziness and vertigo) were detecte ...
... other alpha-adrenergic blocking agents have not been determined. However, interactions may be expected and Maxflo-U® should not be used in combination with other alpha-adrenergic blocking agents. Warning The signs and symptoms of orthostasis (postural hypotension, dizziness and vertigo) were detecte ...
Management of adult acne - Toronto Dermatology Centre
... count over eight weeks to the tetracyclines. It is not a first-line antibiotic because of increased resistance and its gastrointestinal effects. Erythromycin is reserved for instances where tetracyclines are contraindicated, such as in patients younger than eight or in pregnancy.7 Trimethoprim with ...
... count over eight weeks to the tetracyclines. It is not a first-line antibiotic because of increased resistance and its gastrointestinal effects. Erythromycin is reserved for instances where tetracyclines are contraindicated, such as in patients younger than eight or in pregnancy.7 Trimethoprim with ...
PreviDent 5000 - Colgate Professional
... damage in rodents, while other studies using similar protocols report negative results. Potential adverse reproductive effects of fluoride exposure in humans has not been adequately evaluated. Adverse effects on reproduction were reported for rats, mice, fox, and cattle exposed to 100 ppm or greater ...
... damage in rodents, while other studies using similar protocols report negative results. Potential adverse reproductive effects of fluoride exposure in humans has not been adequately evaluated. Adverse effects on reproduction were reported for rats, mice, fox, and cattle exposed to 100 ppm or greater ...
Corticosteroids in the treatment of dengue shock syndrome
... distinct serotypes (DENV-1, 2, 3, 4).1 Dengue is spread between humans by mosquitoes of the Aedes genus, ie, Aedes aegypti and Aedes albopictus.2 Following infection with one of the serotypes, lifelong immunity develops, which is type specific. Serious disease occurs frequently, though not exclusive ...
... distinct serotypes (DENV-1, 2, 3, 4).1 Dengue is spread between humans by mosquitoes of the Aedes genus, ie, Aedes aegypti and Aedes albopictus.2 Following infection with one of the serotypes, lifelong immunity develops, which is type specific. Serious disease occurs frequently, though not exclusive ...
Digitalis Intoxication
... digitalis concentrations in individuals, and the so-called ‘PTQ score’ (which combines PR and QT intervals and an assessment of the T-wave) may prove useful in distinguishing toxic from non-toxic individuals 1201. The technique has not yet been proven to be valuable in routine clinical use, although ...
... digitalis concentrations in individuals, and the so-called ‘PTQ score’ (which combines PR and QT intervals and an assessment of the T-wave) may prove useful in distinguishing toxic from non-toxic individuals 1201. The technique has not yet been proven to be valuable in routine clinical use, although ...
Methadone Conversion Guideline
... • A dosage of about 26 mg per day of methadone can be given as 7.5 mg to 10 mg of methadone three times per day (total daily dose of methadone being either 22.5mg or 30mg respectively). • When ordering methadone, because of its long and variable half-life, always write “hold for sedation.” ...
... • A dosage of about 26 mg per day of methadone can be given as 7.5 mg to 10 mg of methadone three times per day (total daily dose of methadone being either 22.5mg or 30mg respectively). • When ordering methadone, because of its long and variable half-life, always write “hold for sedation.” ...
Celecoxib Pfizer, Capsule
... Long-term administration of NSAIDs has resulted in renal papillary necrosis and other renal injury. Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. In these patients, administration of a NSAID may cause a dose ...
... Long-term administration of NSAIDs has resulted in renal papillary necrosis and other renal injury. Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. In these patients, administration of a NSAID may cause a dose ...
Pharmacologic Management of Allergic Conjunctivitis
... disease they cause, divergence from these patterns occurs commonly in real life, rendering the distinction between “seasonal” and “perennial” allergies somewhat academic. Patients with “seasonal” allergies may have symptoms for the majority of the year if they are sensitive to a perennial allergen, ...
... disease they cause, divergence from these patterns occurs commonly in real life, rendering the distinction between “seasonal” and “perennial” allergies somewhat academic. Patients with “seasonal” allergies may have symptoms for the majority of the year if they are sensitive to a perennial allergen, ...
PAXIL PRODUCT MONOGRAPH
... or threatened death or serious injury, or threat to the physical integrity of self or others, and a response which involves intense fear, helplessness, or horror. Symptoms that occur as a result of exposure to the traumatic event include reexperiencing of the event in the form of intrusive thoughts, ...
... or threatened death or serious injury, or threat to the physical integrity of self or others, and a response which involves intense fear, helplessness, or horror. Symptoms that occur as a result of exposure to the traumatic event include reexperiencing of the event in the form of intrusive thoughts, ...
Paxil - GlaxoSmithKline
... or threatened death or serious injury, or threat to the physical integrity of self or others, and a response which involves intense fear, helplessness, or horror. Symptoms that occur as a result of exposure to the traumatic event include reexperiencing of the event in the form of intrusive thoughts, ...
... or threatened death or serious injury, or threat to the physical integrity of self or others, and a response which involves intense fear, helplessness, or horror. Symptoms that occur as a result of exposure to the traumatic event include reexperiencing of the event in the form of intrusive thoughts, ...
PAXIL CR™ PRODUCT MONOGRAPH
... instability with possible rapid fluctuations of vital signs, and mental status changes that include extreme agitation progressing to delirium and coma. These reactions have also been reported in patients who have recently discontinued SSRI treatment and have begun treatment on a MAO inhibitor. Some ...
... instability with possible rapid fluctuations of vital signs, and mental status changes that include extreme agitation progressing to delirium and coma. These reactions have also been reported in patients who have recently discontinued SSRI treatment and have begun treatment on a MAO inhibitor. Some ...
Ofloxacin
Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.