Conjunctivitis (Red Eye) - Boston Health Care for the Homeless
... or NSAID ketorolac (AcularTM). A third line is available in more potent mast cell stabilizers, e.g. cromolyn sodium (CrocomTM) or ledoxamide tromethamune (AlomideTM). Many patients with allergic conjunctivitis suffer from concurrent rhinitis or dermatitis, for which they will often take systemic ant ...
... or NSAID ketorolac (AcularTM). A third line is available in more potent mast cell stabilizers, e.g. cromolyn sodium (CrocomTM) or ledoxamide tromethamune (AlomideTM). Many patients with allergic conjunctivitis suffer from concurrent rhinitis or dermatitis, for which they will often take systemic ant ...
GLUCAGON FOR INJECTION (rDNA ORIGIN)
... Pregnancy Category B — Reproduction studies have not been performed with recombinant glucagon. However, studies with animal-sourced glucagon were performed in rats at doses up to 2 mg/kg glucagon administered two times a day (up to 40 times the human dose based on body surface area, mg/m2), and have ...
... Pregnancy Category B — Reproduction studies have not been performed with recombinant glucagon. However, studies with animal-sourced glucagon were performed in rats at doses up to 2 mg/kg glucagon administered two times a day (up to 40 times the human dose based on body surface area, mg/m2), and have ...
HYZAAR® HYZAAR® DS
... The possibility of exacerbation or activation of systemic lupus erythematosus has been reported in patients treated with hydrochlorothiazide. Special Populations Pregnant Women: Drugs that act directly on the renin-angiotensin-aldosterone-system (RAAS) can cause fetal and neonatal morbidity and deat ...
... The possibility of exacerbation or activation of systemic lupus erythematosus has been reported in patients treated with hydrochlorothiazide. Special Populations Pregnant Women: Drugs that act directly on the renin-angiotensin-aldosterone-system (RAAS) can cause fetal and neonatal morbidity and deat ...
product information
... clinical trial in which 408 patients were randomised, angiograms were evaluated at baseline and at three years in 264 patients. No statistically significant difference between pravastatin and placebo was seen for the primary endpoint (per patient change in mean coronary artery diameter), or for one ...
... clinical trial in which 408 patients were randomised, angiograms were evaluated at baseline and at three years in 264 patients. No statistically significant difference between pravastatin and placebo was seen for the primary endpoint (per patient change in mean coronary artery diameter), or for one ...
TRIDURAL Product Monograph
... The safety and use of TRIDURAL® in patients under 18 years of age has not been established. The use of TRIDURAL® in the pediatric population is not recommended. Geriatrics (> 65 years of age): In general, caution should be used when selecting the dose for an elderly patient. The elimination half-lif ...
... The safety and use of TRIDURAL® in patients under 18 years of age has not been established. The use of TRIDURAL® in the pediatric population is not recommended. Geriatrics (> 65 years of age): In general, caution should be used when selecting the dose for an elderly patient. The elimination half-lif ...
Drug-induced acute angle closure glaucoma
... antiepileptic agent. Since it was approved in 1995, several case reports have been published addressing its ocular side effects, including AACG, transient myopia and uveal effusion [38–42,43,44,45]. The majority of adverse cases have occurred in females (89%), in paediatric patients as well as ad ...
... antiepileptic agent. Since it was approved in 1995, several case reports have been published addressing its ocular side effects, including AACG, transient myopia and uveal effusion [38–42,43,44,45]. The majority of adverse cases have occurred in females (89%), in paediatric patients as well as ad ...
Abilify ® (Aripiprazole Tablets) - Bristol
... Because ABILIFY was not marketed at the time these studies were performed, it is not known if ABILIFY is associated with this increased risk. Precise risk estimates for hyperglycemia-related adverse events in patients treated with atypical antipsychotics are not available. Patients should have basel ...
... Because ABILIFY was not marketed at the time these studies were performed, it is not known if ABILIFY is associated with this increased risk. Precise risk estimates for hyperglycemia-related adverse events in patients treated with atypical antipsychotics are not available. Patients should have basel ...
Reyataz - Products - Bristol
... PPIs and H2RAs in adults also apply to pediatric patients. See Drug Interactions (7) for instructions concerning coadministration of acid reducing medications (eg, H2RA or PPIs), and other antiretroviral drugs (eg, efavirenz, tenofovir, and didanosine). b For pediatric patients at least 25 kg who ca ...
... PPIs and H2RAs in adults also apply to pediatric patients. See Drug Interactions (7) for instructions concerning coadministration of acid reducing medications (eg, H2RA or PPIs), and other antiretroviral drugs (eg, efavirenz, tenofovir, and didanosine). b For pediatric patients at least 25 kg who ca ...
abnormalities, coronary artery disease, or other serious heart problems. (5.1)
... Doses may be increased in 18 mg increments at weekly intervals for patients who have not achieved an optimal response at a lower dose. Daily dosages above 54 mg in children and 72 mg in adolescents have not been studied and are not recommended. Daily dosages above 72 mg in adults are not recommended ...
... Doses may be increased in 18 mg increments at weekly intervals for patients who have not achieved an optimal response at a lower dose. Daily dosages above 54 mg in children and 72 mg in adolescents have not been studied and are not recommended. Daily dosages above 72 mg in adults are not recommended ...
Paracetamol - A Review of Three Routes of Administration - e
... but the concentrations required to provide analgesia are not well defined.9 One study, in which 120 children were given oral or rectal paracetamol post tonsillectomy, concluded an effect site concentration of 10mcg.ml-1 was needed to achieve pain scores of less than 4/10.10 However, both higher and ...
... but the concentrations required to provide analgesia are not well defined.9 One study, in which 120 children were given oral or rectal paracetamol post tonsillectomy, concluded an effect site concentration of 10mcg.ml-1 was needed to achieve pain scores of less than 4/10.10 However, both higher and ...
Consensus Guidelines for Managing Postoperative - STOP-Bang
... would need to be treated with a single dose of this drug for one to develop headache who would not have done so had they all received a placebo (37). Dexamethasone. Dexamethasone, administered at a prophylactic dose of 8 –10 mg IV, effectively prevents nausea and vomiting with a NNT of approximately ...
... would need to be treated with a single dose of this drug for one to develop headache who would not have done so had they all received a placebo (37). Dexamethasone. Dexamethasone, administered at a prophylactic dose of 8 –10 mg IV, effectively prevents nausea and vomiting with a NNT of approximately ...
What’s special about methadone?
... side effects such as slowed or stopped breathing, and dangerous changes in heart beat in patients receiving methadone. These serious side effects may occur because methadone may build up in the body to a toxic level if it is taken too often, if the amount taken is too high, or if it is taken with ce ...
... side effects such as slowed or stopped breathing, and dangerous changes in heart beat in patients receiving methadone. These serious side effects may occur because methadone may build up in the body to a toxic level if it is taken too often, if the amount taken is too high, or if it is taken with ce ...
Full Prescribing Information for CONCERTA® (methylphenidate HCl)
... Doses may be increased in 18 mg increments at weekly intervals for patients who have not achieved an optimal response at a lower dose. Daily dosages above 54 mg in children and 72 mg in adolescents have not been studied and are not recommended. Daily dosages above 72 mg in adults are not recommended ...
... Doses may be increased in 18 mg increments at weekly intervals for patients who have not achieved an optimal response at a lower dose. Daily dosages above 54 mg in children and 72 mg in adolescents have not been studied and are not recommended. Daily dosages above 72 mg in adults are not recommended ...
Full Prescribing Information for CONCERTA
... Doses may be increased in 18 mg increments at weekly intervals for patients who have not achieved an optimal response at a lower dose. Daily dosages above 54 mg in children and 72 mg in adolescents have not been studied and are not recommended. Daily dosages above 72 mg in adults are not recommended ...
... Doses may be increased in 18 mg increments at weekly intervals for patients who have not achieved an optimal response at a lower dose. Daily dosages above 54 mg in children and 72 mg in adolescents have not been studied and are not recommended. Daily dosages above 72 mg in adults are not recommended ...
Minoxidil Topical Solution USP 2%
... mg per day, as tolerated, to a recommended dose of 3 mg per day. Although efficacy has been demonstrated in studies of adolescent patients with schizophrenia at doses between 1 mg to 6 mg per day, no additional benefit was observed above 3 mg per day, and higher doses were associated with more adver ...
... mg per day, as tolerated, to a recommended dose of 3 mg per day. Although efficacy has been demonstrated in studies of adolescent patients with schizophrenia at doses between 1 mg to 6 mg per day, no additional benefit was observed above 3 mg per day, and higher doses were associated with more adver ...
concerta - Janssen
... alcoholism. Chronic abusive use can lead to marked tolerance and psychological dependence with varying degrees of abnormal behaviour. Frank psychotic episodes can occur, especially with parenteral abuse (See DOSAGE AND ADMINISTRATION, Administration). Careful supervision is required during withdrawa ...
... alcoholism. Chronic abusive use can lead to marked tolerance and psychological dependence with varying degrees of abnormal behaviour. Frank psychotic episodes can occur, especially with parenteral abuse (See DOSAGE AND ADMINISTRATION, Administration). Careful supervision is required during withdrawa ...
Antihistamines in pediatric allergy
... on H1 receptors, it is clear that antiH1antihistamines are the most common drugs used to treat allergic diseases.8 H1 antihistamines are not receptor antagonists as previously thought, but are inverse agonists.9 When neither histamine nor antihistamine is present, the active and inactive states of t ...
... on H1 receptors, it is clear that antiH1antihistamines are the most common drugs used to treat allergic diseases.8 H1 antihistamines are not receptor antagonists as previously thought, but are inverse agonists.9 When neither histamine nor antihistamine is present, the active and inactive states of t ...
Optimal dosing strategies for maximising the clinical response to
... steps, or whether only two titration steps were needed. Not surprisingly, the patients requiring more than two titration steps had more severe diabetes at baseline, as indicated by a higher mean FPG (figure 4). In both groups progressive increases in antihyperglycaemic efficacy were observed with ea ...
... steps, or whether only two titration steps were needed. Not surprisingly, the patients requiring more than two titration steps had more severe diabetes at baseline, as indicated by a higher mean FPG (figure 4). In both groups progressive increases in antihyperglycaemic efficacy were observed with ea ...
A Practical Approach to the Treatment of Low
... these agents to administer if the child is distressed. This narrative literature review examines recent data on ibuprofen and paracetamol in feverish children to determine any clinically relevant differences between these agents. The data suggest that these agents have similar safety profiles in thi ...
... these agents to administer if the child is distressed. This narrative literature review examines recent data on ibuprofen and paracetamol in feverish children to determine any clinically relevant differences between these agents. The data suggest that these agents have similar safety profiles in thi ...
METRONIDAZOLE INTRAVENOUS INFUSION
... dosage of lithium has been reported to increase serum lithium concentrations, resulting in signs of lithium toxicity in several patients. Serum lithium and serum creatinine levels should be obtained several days after commencing metronidazole therapy to detect any increase that may precede clinical ...
... dosage of lithium has been reported to increase serum lithium concentrations, resulting in signs of lithium toxicity in several patients. Serum lithium and serum creatinine levels should be obtained several days after commencing metronidazole therapy to detect any increase that may precede clinical ...
Imatinib - BC Cancer Agency
... female patients are not pregnant prior to treatment with imatinib. Effective contraception should be used during ...
... female patients are not pregnant prior to treatment with imatinib. Effective contraception should be used during ...
Rosiver - Galderma
... ivermectin peaked within 10 ± 8 hours post-dose (Cmax: 2.10 ± 1.04 ng/mL range: 0.69 - 4.02 ng/mL) and the highest mean (± standard deviation) AUC0-24hr was 36.14 ± 15.56 ng.hr/mL (range: 13.69-75.16 ng.hr/mL). In addition, systemic exposure assessment in longer treatment duration (Phase 3 studies) ...
... ivermectin peaked within 10 ± 8 hours post-dose (Cmax: 2.10 ± 1.04 ng/mL range: 0.69 - 4.02 ng/mL) and the highest mean (± standard deviation) AUC0-24hr was 36.14 ± 15.56 ng.hr/mL (range: 13.69-75.16 ng.hr/mL). In addition, systemic exposure assessment in longer treatment duration (Phase 3 studies) ...
Guideline for the Management of Postoperative Nausea and Vomiting
... Prophylactic doses and timing for the administration of antiemetics are shown in Table 2. Serotonin (5-HT3) receptor antagonists exert their effects in the chemoreceptor trigger zone and at vagal afferents in the gastrointestinal tract. Ondansetron was the first of this class of drug to be marketed; ...
... Prophylactic doses and timing for the administration of antiemetics are shown in Table 2. Serotonin (5-HT3) receptor antagonists exert their effects in the chemoreceptor trigger zone and at vagal afferents in the gastrointestinal tract. Ondansetron was the first of this class of drug to be marketed; ...
PRODUCT MONOGRAPH Pr LAMISIL® Terbinafine tablets 250 mg
... patients taking LAMISIL tablets concomitantly with oral contraceptives, although the incidence of these disorders remains within the background incidence of patients taking oral contraceptives alone. There are no data to suggest special recommendations for women of child-bearing potential. Pregnant ...
... patients taking LAMISIL tablets concomitantly with oral contraceptives, although the incidence of these disorders remains within the background incidence of patients taking oral contraceptives alone. There are no data to suggest special recommendations for women of child-bearing potential. Pregnant ...
Determine by Doctor
... achieved with corresponding dosages of the conventional (immediaterelease) tablets every 6 hours. Although one manufacturer states that peak plasma concentrations may be higher with chewable tablets than with conventional tablets, a crossover study employing this manufacturer’s tablets in adults wit ...
... achieved with corresponding dosages of the conventional (immediaterelease) tablets every 6 hours. Although one manufacturer states that peak plasma concentrations may be higher with chewable tablets than with conventional tablets, a crossover study employing this manufacturer’s tablets in adults wit ...
Ofloxacin
Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.