Bromazepam
... early case-control epidemiological studies have found an increased risk of oral clefts. The data indicated that the risk of having an infant with an oral cleft after maternal benzodiazepine exposure is less than 2/1000 compared with an expected rate for such defects of approximately 1/1000 in the ge ...
... early case-control epidemiological studies have found an increased risk of oral clefts. The data indicated that the risk of having an infant with an oral cleft after maternal benzodiazepine exposure is less than 2/1000 compared with an expected rate for such defects of approximately 1/1000 in the ge ...
Appropriate Drug Prescribing in Older Adults
... ethanol, some antibiotics and anti-arrhythmics), resulting in higher peak levels Increases Vd (reservoir) of drugs distributed to adipose (amiodarone, diazepam, haloperidol) Particularly important for “loading” doses Protein Binding: Often decreased in older patients Can result in higher fre ...
... ethanol, some antibiotics and anti-arrhythmics), resulting in higher peak levels Increases Vd (reservoir) of drugs distributed to adipose (amiodarone, diazepam, haloperidol) Particularly important for “loading” doses Protein Binding: Often decreased in older patients Can result in higher fre ...
Digoxin – Loading Dose Guide (Adults)
... Prescribe and administer the loading dose in 2 portions with half of the total dose given as the first portion and the second portion 6 hours later. Write “LOADING Dose” on the prescription Add dose to 50 - 100mL of Sodium chloride 0.9% or glucose 5% Administer using a rate controlled infusion pump ...
... Prescribe and administer the loading dose in 2 portions with half of the total dose given as the first portion and the second portion 6 hours later. Write “LOADING Dose” on the prescription Add dose to 50 - 100mL of Sodium chloride 0.9% or glucose 5% Administer using a rate controlled infusion pump ...
Package Insert
... Finasteride reduces both circulating and intraprostatic DHT concentrations. Within 24 hours after oral administration of finasteride, there is a significant reduction in circulating DHT levels as a result of the inhibition of 5-alpha-reductase. Pharmacokinetics: Following an oral dose of 14C-finaste ...
... Finasteride reduces both circulating and intraprostatic DHT concentrations. Within 24 hours after oral administration of finasteride, there is a significant reduction in circulating DHT levels as a result of the inhibition of 5-alpha-reductase. Pharmacokinetics: Following an oral dose of 14C-finaste ...
, NEW REASON * TO SWITCH TO CARDIZEM CD 0""
... rabbits. Administration of doses ranging from live to ten limes greater (on a mg/kg basis) than Ihe daily recommended therapeutic dose has resulted in embryo and fetal lethality. These doses, in some studies, have been reported to cause skeletal abnormalities. In the perinatal/postnatal studies, the ...
... rabbits. Administration of doses ranging from live to ten limes greater (on a mg/kg basis) than Ihe daily recommended therapeutic dose has resulted in embryo and fetal lethality. These doses, in some studies, have been reported to cause skeletal abnormalities. In the perinatal/postnatal studies, the ...
Prescribing Information - PI
... and 2,000 mg/kg/day omega-3 carboxylic acid, males were treated for 84 to 95 weeks without an increased incidence of tumors. In female rats treated for 66 to 95 weeks at 2000 mg/kg/day, an increased incidence of benign ovarian sex cord stromal tumors was observed (up to 5 times human systemic exposu ...
... and 2,000 mg/kg/day omega-3 carboxylic acid, males were treated for 84 to 95 weeks without an increased incidence of tumors. In female rats treated for 66 to 95 weeks at 2000 mg/kg/day, an increased incidence of benign ovarian sex cord stromal tumors was observed (up to 5 times human systemic exposu ...
Here are some of these formulations
... 3 times a day. Doses can be increased according to patients needs but doses above 120 milligrams per day are not recommended . N.B. If you miss a dose take it as soon as you remember it . If it is almost time for the next dose , skip the missed dose and continue your regular dosing schedule . Never ...
... 3 times a day. Doses can be increased according to patients needs but doses above 120 milligrams per day are not recommended . N.B. If you miss a dose take it as soon as you remember it . If it is almost time for the next dose , skip the missed dose and continue your regular dosing schedule . Never ...
Rizatriptan Orifarm tablet ENG SmPC
... [Product name] should not be used to treat atypical headaches, i.e. those that might be associated with potentially serious medical conditions (e.g. CVA, ruptured aneurysm) in which cerebrovascular vasoconstriction could be harmful. Rizatriptan can be associated with transient symptoms including ch ...
... [Product name] should not be used to treat atypical headaches, i.e. those that might be associated with potentially serious medical conditions (e.g. CVA, ruptured aneurysm) in which cerebrovascular vasoconstriction could be harmful. Rizatriptan can be associated with transient symptoms including ch ...
Information for Patients
... Nitisinone has been studied in patients ranging in age from birth to 21.7 years. The median age of enrolment in a study of 207 patients with HT-1 was 9 months. Geriatric Use ...
... Nitisinone has been studied in patients ranging in age from birth to 21.7 years. The median age of enrolment in a study of 207 patients with HT-1 was 9 months. Geriatric Use ...
Anti-Emetic Guidelines For Chemotherapy Patients
... consultation with medical staff. Anti-emetics should be given prior to chemotherapy and for at least 3-days following treatment if delayed nausea and vomiting are expected (as with cisplatin). 3. Give psychological support to prevent and reduce the stress of anticipatory nausea and vomiting. The use ...
... consultation with medical staff. Anti-emetics should be given prior to chemotherapy and for at least 3-days following treatment if delayed nausea and vomiting are expected (as with cisplatin). 3. Give psychological support to prevent and reduce the stress of anticipatory nausea and vomiting. The use ...
immunosuppressed patients - Enlighten: Publications
... With the advent of highly active antiretroviral therapy (HAART), the prognosis of patients with HIV and AIDS has improved enormously. Compared with other ICU groups with similar severity of illness, HIV patients no longer have a worse outcome. Patients are increasingly admitted to the ICU with HIV a ...
... With the advent of highly active antiretroviral therapy (HAART), the prognosis of patients with HIV and AIDS has improved enormously. Compared with other ICU groups with similar severity of illness, HIV patients no longer have a worse outcome. Patients are increasingly admitted to the ICU with HIV a ...
Factors that may cause Bleeding with Enoxaparin
... failure (P=0.012) than patients with normal renal function. The ...
... failure (P=0.012) than patients with normal renal function. The ...
Orlistat (Alli, Xenical)
... Year of approval: 1999 (Xenical – prescription 120 mg TID), 2007 (Alli – OTC 60 mg) FDA approved indication: as an adjunct to a reduced-calorie and low-fat diet for weight loss or to lower the risk of regaining weight after prior weight loss Efficacy: 2.9 kg mean weight loss (Xenical) beyond that ac ...
... Year of approval: 1999 (Xenical – prescription 120 mg TID), 2007 (Alli – OTC 60 mg) FDA approved indication: as an adjunct to a reduced-calorie and low-fat diet for weight loss or to lower the risk of regaining weight after prior weight loss Efficacy: 2.9 kg mean weight loss (Xenical) beyond that ac ...
Pleiotropic Effects of Antimicrobial Agents
... Although unintended effects of antimicrobial agents occur, some effects may produce therapeutic advantages. Many anti-infective agents have effects that stem beyond their anti-infectiveness. These advantages include anti-inflammatory and immunomodulatory properties. The other therapeutic advantages ...
... Although unintended effects of antimicrobial agents occur, some effects may produce therapeutic advantages. Many anti-infective agents have effects that stem beyond their anti-infectiveness. These advantages include anti-inflammatory and immunomodulatory properties. The other therapeutic advantages ...
09. antiamoebic drug..
... Metabolized & Excreted slowly via kidney so it has a cumulative effect. Trace amounts could be detected in urine 12 month after last dose. Should not be used for more than 10 days (usually 3-5 days). ...
... Metabolized & Excreted slowly via kidney so it has a cumulative effect. Trace amounts could be detected in urine 12 month after last dose. Should not be used for more than 10 days (usually 3-5 days). ...
Antibiotic use in critical care
... In humans, AUC/MIC value >350 was an independent factor associated with clinical success in patients with S.aureus proven lower respiratory tract infection ...
... In humans, AUC/MIC value >350 was an independent factor associated with clinical success in patients with S.aureus proven lower respiratory tract infection ...
the Dosing Guide
... patients treated with Corlanor® compared to placebo was 5% vs. 3.9% per patient-year, respectively. Regularly monitor cardiac rhythm. Discontinue Corlanor® if atrial fibrillation develops. Bradycardia and Conduction Disturbances: Bradycardia, sinus arrest and heart block have occurred with Corlanor® ...
... patients treated with Corlanor® compared to placebo was 5% vs. 3.9% per patient-year, respectively. Regularly monitor cardiac rhythm. Discontinue Corlanor® if atrial fibrillation develops. Bradycardia and Conduction Disturbances: Bradycardia, sinus arrest and heart block have occurred with Corlanor® ...
Samples of exam questions and answers
... 16. The mechanism of antibacterial action of tetracyclines involves A) inhibition of the conversion of lanosterol to ergosterol B) inhibition of DNA – dependent RNA polymerase C) blockade of binding of aminoacyl – RNA to bacterial ribosomes D) selective inhibition of ribosomal peptidyltransferases 1 ...
... 16. The mechanism of antibacterial action of tetracyclines involves A) inhibition of the conversion of lanosterol to ergosterol B) inhibition of DNA – dependent RNA polymerase C) blockade of binding of aminoacyl – RNA to bacterial ribosomes D) selective inhibition of ribosomal peptidyltransferases 1 ...
meperidine - DavisPlus
... the patient reports satisfactory pain relief. A repeat dose can be safely administered at the time of the peak if previous dose is ineffective and side effects are minimal. An equianalgesic chart (see Appendix B) should be used when changing routes or when changing from one opioid to another. Assess ...
... the patient reports satisfactory pain relief. A repeat dose can be safely administered at the time of the peak if previous dose is ineffective and side effects are minimal. An equianalgesic chart (see Appendix B) should be used when changing routes or when changing from one opioid to another. Assess ...
Antiamoebic Drugs
... 6- Emetine is metabolized and excreted slowly via the kidneys; it has a cumulative effect. 7- Trace amounts could be detected in urine 1-2 months after the last dose. 8- Emetine should not be used for more than 10 days (usually 3-5 days). Pharmacological Actions: 1- Emetine acts on trophozoites ca ...
... 6- Emetine is metabolized and excreted slowly via the kidneys; it has a cumulative effect. 7- Trace amounts could be detected in urine 1-2 months after the last dose. 8- Emetine should not be used for more than 10 days (usually 3-5 days). Pharmacological Actions: 1- Emetine acts on trophozoites ca ...
baclofen
... • It is the pain that causes the major disability, and unfortunately, this is very difficult to treat. A few patients have responded to sympathetic blockade, but in the majority, this is ineffective. A course of guanethidine blocks into the affected limb is worth trying. Transcutaneous electrical ne ...
... • It is the pain that causes the major disability, and unfortunately, this is very difficult to treat. A few patients have responded to sympathetic blockade, but in the majority, this is ineffective. A course of guanethidine blocks into the affected limb is worth trying. Transcutaneous electrical ne ...
DE56A271P - Buclizine hydrochloride
... symptoms and had often failed to obtain relief by other measures, including injections of allergeu The patients who were receiving injections (22 per cent ) continned to do so, but were urged to avoid other antihistaminic drugs- Seventyfive milligrams of buclizine per day was prescribed, to be taken ...
... symptoms and had often failed to obtain relief by other measures, including injections of allergeu The patients who were receiving injections (22 per cent ) continned to do so, but were urged to avoid other antihistaminic drugs- Seventyfive milligrams of buclizine per day was prescribed, to be taken ...
AEDs - BC Epilepsy Society
... inhibitor), or ethinyl estradiol + levonorgestrel-containing oral contraceptives. – Caution should be exercised when VIMPAT is given with other drugs that prolong the PR interval (eg. carbamazepine, pregabalin, lamotrigine or beta-blockers), and in patients treated with class I anti-arrhythmic drugs ...
... inhibitor), or ethinyl estradiol + levonorgestrel-containing oral contraceptives. – Caution should be exercised when VIMPAT is given with other drugs that prolong the PR interval (eg. carbamazepine, pregabalin, lamotrigine or beta-blockers), and in patients treated with class I anti-arrhythmic drugs ...
Treatment of nausea and vomiting during pregnancy
... to cause restlessness, drowsiness and fatigue in up to 10% of patients and, less commonly, dystonic reactions (0.2%). Women with hyperemesis gravidarum may need therapy with more than one antiemetic with different mechanisms of action. Second-line agents include ondansetron (antagonises serotonin [5 ...
... to cause restlessness, drowsiness and fatigue in up to 10% of patients and, less commonly, dystonic reactions (0.2%). Women with hyperemesis gravidarum may need therapy with more than one antiemetic with different mechanisms of action. Second-line agents include ondansetron (antagonises serotonin [5 ...
Pharmacist Activist T
... Therapeutics) is the first drug to be approved for the treatment of chronic angina in more than a decade, and its structural and pharmacologic characteristics differ from those of the long-acting nitrates (e.g., isosorbide mononitrate [e.g., Imdur]), beta-blockers (e.g., atenolol [e.g., Tenormin]) an ...
... Therapeutics) is the first drug to be approved for the treatment of chronic angina in more than a decade, and its structural and pharmacologic characteristics differ from those of the long-acting nitrates (e.g., isosorbide mononitrate [e.g., Imdur]), beta-blockers (e.g., atenolol [e.g., Tenormin]) an ...
Ofloxacin
Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.