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Single dose fluconazole in the treatment of pityriasis versicolor
Single dose fluconazole in the treatment of pityriasis versicolor

... trunk.1 It is an anthropophilic fungus belonging to the physiological skin flora, growing in yeast form on non-affected skin and in mycelial form causing clinical disease.2 Although PV is prevalent ...
New Zealand Datasheet  Name of Medicine Presentation
New Zealand Datasheet Name of Medicine Presentation

... the airways, inhibition of M3-receptors at the smooth muscle results in relaxation. The competitive and reversible nature of antagonism was shown with human and animal origin receptors and isolated organ preparations. In non-clinical in vitro as well as in vivo studies bronchoprotective effects were ...
Worst Pills, Best Pills News Now Available Online!
Worst Pills, Best Pills News Now Available Online!

... shown to provide a significant clinical advance over omeprazole in the first-line treatment of patients with acid-related disorders is not supported by data (emphasis supplied by the Medical Officer in the original). What was AstraZeneca's motive in developing esomeprazole, a drug that has not been ...
(PLT) Tablets - Veterinary Medicines Directorate
(PLT) Tablets - Veterinary Medicines Directorate

... corticosteroids and GI tract ulceration may be exacerbated by steroids in patients given non-steroidal anti-inflammatory drugs and in corticosteroid treated animals with spinal cord trauma. Steroids may cause enlargement of the liver (hepatomegaly) with increased serum hepatic enzymes. Gastro-intest ...
Chromoblastomycosis of the Conjunctiva Mimicking
Chromoblastomycosis of the Conjunctiva Mimicking

... Methods. The study was approved by the Institutional Review Board of the University of Miami School of Medicine Medical Sciences Subcommittee for the Protection of Human Subjects. This was a retrospective, noncomparative, consecutive case series. We reviewed the microbiological and medical records o ...
NSAIDs: Friend or Foe
NSAIDs: Friend or Foe

... Exists in 2 forms – COX-1 and COX-2 Analgesic and anti-inflammatory effect mainly dependent on COX-2 Unwanted GI side effects due to inhibition of COX-1 ...
NSAIDs: Friend or Foe
NSAIDs: Friend or Foe

... Exists in 2 forms – COX-1 and COX-2 Analgesic and anti-inflammatory effect mainly dependent on COX-2 Unwanted GI side effects due to inhibition of COX-1 ...
When to Spare Some Pharmaceutical Care
When to Spare Some Pharmaceutical Care

... Geriatric Syndromes Morbidity/Mortality ...
Chromoblastomycosis of the Conjunctiva Mimicking Melanoma of
Chromoblastomycosis of the Conjunctiva Mimicking Melanoma of

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Piperacillin-Tazobactam Toxicity Questions the Need for Pediatric

... the neutrophil count obtained at the end of treatment. Therefore, this article suggests that prolonged use of piperacillin-tazobactam at the suggested dose for the treatment of bone-related infections should be administered cautiously, particularly for younger patients. Piperacillin-tazobactam (Zosy ...
Hypertension update
Hypertension update

... HTN in ESRD BP should be controlled prior starting epoetin Bone marrow depression up to 10% in renal failure patients on captopril (sulfhydryl gp.) especially autoimmune disease, therefore close monitor of WBC, and low dose captopril. Central alpha-2 agonists as clonidine appear to be the safest in ...
Antiinfective drugs Chemotherapy: is the treatment of a disease by
Antiinfective drugs Chemotherapy: is the treatment of a disease by

... oxygen-requiring transport system which is necessory to transport antibiotics across the cell membrane.They are effective against most gram-negative and many gram-positive bacteria. Side effects: Include serious side effects, such as nephrotoxicity, ototoxicity and neuromuscular synaptic dysfunction ...
View PDF - Auspherix
View PDF - Auspherix

... could benefit from a pre-treatment to prevent post-surgical infection from these bacteria,” the executive commented. An estimated one in three people are carriers of nasal Staphylococcus aureus, one of the staphylococcal bacteria. A healthy individual is not harmed by the bacteria. But if he or she ...
Antibacterials
Antibacterials

... administered orally and distributed throughout the tissues. Patients should be advised that it may tinge body fluids red. It is an inducer of the p450 system and so interacts with many other agents and can lead to hepatitis. Pyrazinamide is active only at acidic pH. After phagocytosis, the mycobacte ...
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... ketorolac tromethamine Only injectable NSAID. In addition to acid (Toradol) other PSI effects, is nephrotoxic with derivatives long-term use and causes drowsiness. Actions and Uses Prostaglandin synthetase inhibitors prevent the synthesis and release of prostaglandins. They are useful in a variety o ...
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Full Prescribing Information
Full Prescribing Information

... 2.2 Preparation and Handling Instructions 1. Visually inspect the ERWINAZE powder for foreign particulate matter and discoloration prior to reconstitution. Discard vial if present. 2. Reconstitute the contents of each vial by slowly injecting 1 or 2 mL of preservative free sterile sodium chloride (0 ...
A) ATB inhibiting bacterial cell wall synthesis
A) ATB inhibiting bacterial cell wall synthesis

... zoonoses (tularemia, brucellosis etc.) prostatitis acute exacerbation of chronic bronchitis lower respiratory tract infections in cystic fibrosis common UTI gastroenteritis, enterocolitis biliary infections (+ prophylaxis) uretritis (STD) nosocomial infections, sepsis ...
Carisoprodol (Soma®) - Texas Medicaid/CHIP Vendor Drug Program
Carisoprodol (Soma®) - Texas Medicaid/CHIP Vendor Drug Program

... Cyclobenzaprine therapy for muscle spasm should not last longer than three weeks as efficacy beyond this time period has not been demonstrated. Limited information exists regarding carisoprodol therapy duration for muscle spasm. As carisoprodol has been evaluated only for use in the treatment of ac ...
The modern management of gout
The modern management of gout

...  Sulphinpyrazone inhibits prostaglandin synthesis much like the NSAIDs and therefore its Aes are similar including gastro-intestinal ulceration,acute renal failure, fluid retention and rarely elevation of liver enzymes and blood disorders. Sulphinpyrazone 200–800mg daily in divided doses is used. ...
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Mechanism of Action

... – At higher concentrations, it also inhibits DNA synthesis. Interstrand and DNAprotein cross-links may also occur. (cell cycle phase-nonspecific) ...
Journal Club: Trimethoprim-Sulfamethoxazole verses Placebo for
Journal Club: Trimethoprim-Sulfamethoxazole verses Placebo for

...  Response to abscess treatment with I and D with TMP – SMX at rechecks scheduled at days 3-4, 8-10, and 14-21 (vs response to just I and D).  Criteria for clinical failure at day 3-4 included:  Fever attributable to the abscess  Increase in erythema > 25% from baseline  Worsening wound swelling ...
Product information: Sucroferric oxyhydroxide
Product information: Sucroferric oxyhydroxide

... disorders, and patients with major gastrointestinal surgery have not been included in clinical studies with Velphoro. Velphoro should only be used in these patients following careful assessment of benefit/risk. Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabso ...
Mei 2003
Mei 2003

... originated from the marketing authorisation holder. Two cases of death were reported. One 66-year-old female patient with chronic heart failure and an ejection fraction of 20%, died 10 days after start of tiotropium bromide. The reporting general practitioner considered causality unlikely. In the sa ...
Shared care protocol with Oxfordshire for sulfasalazine SCP 2015
Shared care protocol with Oxfordshire for sulfasalazine SCP 2015

... Sulfasalazine is an established drug with a known side effect profile. Its use in this protocol is limited to: Rheumatology  Rheumatoid arthritis (licensed).  Seronegative spondylarthropathies, including psoriatic arthritis (unlicensed).  It can be used in combination with other DMARDs, such as m ...
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Ofloxacin



Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.
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