PRODUCT MONOGRAPH INCLUDING PATIENT MEDICATION
... pregnancy is confirmed at a follow-up visit. Infections Cases of serious bacterial infection, including very rare cases of fatal septic shock, have been reported following the use of mifepristone and misoprostol. A sustained fever of 38 oC or higher, severe abdominal pain or pelvic tenderness in the ...
... pregnancy is confirmed at a follow-up visit. Infections Cases of serious bacterial infection, including very rare cases of fatal septic shock, have been reported following the use of mifepristone and misoprostol. A sustained fever of 38 oC or higher, severe abdominal pain or pelvic tenderness in the ...
Prescribing Information
... to that of the sympathomimetic amines, it does share some pharmacologic properties with this class. Certain of these drugs have been associated with intrauterine growth restriction and spontaneous abortions. Whether the cases reported with modafinil are drug-related is unknown. In studies of modafin ...
... to that of the sympathomimetic amines, it does share some pharmacologic properties with this class. Certain of these drugs have been associated with intrauterine growth restriction and spontaneous abortions. Whether the cases reported with modafinil are drug-related is unknown. In studies of modafin ...
Slide 1
... It is not until a diagnosis of Stage 2 or 3 AMD is confirmed that the majority of optometrists refer patients to an ophthalmologist or retina specialist . Only 15% of MAP patients diagnosed with Stage 1 AMD were referred. ...
... It is not until a diagnosis of Stage 2 or 3 AMD is confirmed that the majority of optometrists refer patients to an ophthalmologist or retina specialist . Only 15% of MAP patients diagnosed with Stage 1 AMD were referred. ...
The poster sessions are an important highlight of these conferences
... Methods: Phase I study in Ph+ with resistance or intolerance to IM who may have also failed 2 nd generation TKI’s treated with INNO 406 orally at doses ranging from 30 mg QD to 480 mg BID. Part I, the dose finding portion of the study was completed. And additional ten (10) pts were enrolled on the e ...
... Methods: Phase I study in Ph+ with resistance or intolerance to IM who may have also failed 2 nd generation TKI’s treated with INNO 406 orally at doses ranging from 30 mg QD to 480 mg BID. Part I, the dose finding portion of the study was completed. And additional ten (10) pts were enrolled on the e ...
Metabolism, Excretion, and Pharmacokinetics of S-Allyl-L
... Institutional Animal Care and Use Committee. Male Sprague-Dawley rats (230– 280 g, Charles Liver Japan, Yokohama, Japan) and male beagle dogs (10–14 kg, Kitayama Labes, Nagano, Japan) were fasted overnight before the studies. All compounds of NAc-SAC, NAc-SACS, SAC, and SACS were dissolved in distil ...
... Institutional Animal Care and Use Committee. Male Sprague-Dawley rats (230– 280 g, Charles Liver Japan, Yokohama, Japan) and male beagle dogs (10–14 kg, Kitayama Labes, Nagano, Japan) were fasted overnight before the studies. All compounds of NAc-SAC, NAc-SACS, SAC, and SACS were dissolved in distil ...
Morphine Sulfate Extended-Release Tablets
... effector compartments, leading to a lag-time, or hysteresis, between rapid changes in plasma morphine concentrations and the effects of such changes. The most direct and predictable concentration-effect relationships can, therefore, be expected at distribution equilibrium and/or steady state conditi ...
... effector compartments, leading to a lag-time, or hysteresis, between rapid changes in plasma morphine concentrations and the effects of such changes. The most direct and predictable concentration-effect relationships can, therefore, be expected at distribution equilibrium and/or steady state conditi ...
Sotalol versus Amiodarone in Treatment of Atrial Fibrillation
... that evaluated the efficacy of sotalol in comparison to amiodarone were collected for inclusion in this report. Studies could employ either IV or oral route of administration for sotalol or amiodarone. Publications were limited to full text papers written in English. Selected publications must have ...
... that evaluated the efficacy of sotalol in comparison to amiodarone were collected for inclusion in this report. Studies could employ either IV or oral route of administration for sotalol or amiodarone. Publications were limited to full text papers written in English. Selected publications must have ...
Herbal Medicines
... Herbal medicines, cont. • Little to no FDA regulation: – alternative medicines are marketed without efficacy tests – companies do not have to prove their product is safe instead the FDA must prove it is unsafe – no set standards for manufacturing, no quality control – can not claim cures but can te ...
... Herbal medicines, cont. • Little to no FDA regulation: – alternative medicines are marketed without efficacy tests – companies do not have to prove their product is safe instead the FDA must prove it is unsafe – no set standards for manufacturing, no quality control – can not claim cures but can te ...
ACE Inhibitors and Angiotensin II
... often the primary parameter for choice, especially when there are generic versions of the drugs available. This is overlooked when there is the possible benefit for a specific indication, based on non-surrogate efficacy and safety data. Secondary reasons for choice can be surrogate endpoints, such a ...
... often the primary parameter for choice, especially when there are generic versions of the drugs available. This is overlooked when there is the possible benefit for a specific indication, based on non-surrogate efficacy and safety data. Secondary reasons for choice can be surrogate endpoints, such a ...
Distinguishing a Choroidal Nevus From a Choroidal Melanoma
... lesion. Thus, early detection is important. In addition, making the correct diagnosis of choroidal nevi in a timely fashion protects patients against the visually damaging effects of unnecessary treatment. Symptoms Choroidal nevi, which typically are found on routine dilated fundus examination, usua ...
... lesion. Thus, early detection is important. In addition, making the correct diagnosis of choroidal nevi in a timely fashion protects patients against the visually damaging effects of unnecessary treatment. Symptoms Choroidal nevi, which typically are found on routine dilated fundus examination, usua ...
PRESCRIBING INFORMATION CODEINE 15
... constipation and/or urinary retention. Cimetidine: Concurrent administration of cimetidine may lead to increased effect or toxicity of opioid analgesics. CNS Agents: Concomitant administration of other CNS drugs such as sedatives, hypnotics, phenothiazines, anesthetics and alcohol may increase the s ...
... constipation and/or urinary retention. Cimetidine: Concurrent administration of cimetidine may lead to increased effect or toxicity of opioid analgesics. CNS Agents: Concomitant administration of other CNS drugs such as sedatives, hypnotics, phenothiazines, anesthetics and alcohol may increase the s ...
Chronic Kidney Disease - Delaware Valley Academy of Veterinary
... Terms and Concepts Related to Kidney Disease, Kidney Failure, and Uremia Use of the terms kidney disease, kidney insufficiency, kidney failure, azotemia, and uremia as synonyms may result in misdiagnosis and formulation of inappropriate or even contraindicated therapy. It is recommended that the te ...
... Terms and Concepts Related to Kidney Disease, Kidney Failure, and Uremia Use of the terms kidney disease, kidney insufficiency, kidney failure, azotemia, and uremia as synonyms may result in misdiagnosis and formulation of inappropriate or even contraindicated therapy. It is recommended that the te ...
Differential Cardiovascular and Renal Responses Produced by
... Quincy, MA). Heart rate was determined from the arterial pressure signal by a Grass model 7P4 Tachograph. After implantation of these catheters, certain rats (still anesthetized with sodium methohexital) were also implanted with a recording electrode on a renal nerve bundle for direct measurement of ...
... Quincy, MA). Heart rate was determined from the arterial pressure signal by a Grass model 7P4 Tachograph. After implantation of these catheters, certain rats (still anesthetized with sodium methohexital) were also implanted with a recording electrode on a renal nerve bundle for direct measurement of ...
Methylphenidate Hydrochloride Oral Solution
... Do not start any new medicine while taking methylphenidate hydrochloride oral solution without talking to your doctor first. How should methylphenidate hydrochloride oral solution be taken? • Take methylphenidate hydrochloride oral solution exactly as prescribed. Your doctor may adjust the dose unti ...
... Do not start any new medicine while taking methylphenidate hydrochloride oral solution without talking to your doctor first. How should methylphenidate hydrochloride oral solution be taken? • Take methylphenidate hydrochloride oral solution exactly as prescribed. Your doctor may adjust the dose unti ...
View Full Prescribing Information
... ANTHIM is indicated in adult and pediatric patients for the treatment of inhalational anthrax due to Bacillus anthracis in combination with appropriate antibacterial drugs. ANTHIM is indicated for prophylaxis of inhalational anthrax due to B. anthracis when alternative therapies are not available or ...
... ANTHIM is indicated in adult and pediatric patients for the treatment of inhalational anthrax due to Bacillus anthracis in combination with appropriate antibacterial drugs. ANTHIM is indicated for prophylaxis of inhalational anthrax due to B. anthracis when alternative therapies are not available or ...
TCCC Change Prop 1403 Ondansetron 150403 JSOM
... Although the published literature reports no incidents of adverse events, such as those noted above, in combat casualties in Afghanistan and Iraq, the potential exists for these events to occur. Combined with the more advantageous current pricing of generic ondansetron, its potential benefits versus ...
... Although the published literature reports no incidents of adverse events, such as those noted above, in combat casualties in Afghanistan and Iraq, the potential exists for these events to occur. Combined with the more advantageous current pricing of generic ondansetron, its potential benefits versus ...
product monograph
... not been established and therefore, it should not be used in women of childbearing potential or in nursing mothers unless, in the opinion of the physician, the potential benefits to the patient outweigh the possible hazards to the fetus or the infant. Teratology studies conducted in pregnant rats at ...
... not been established and therefore, it should not be used in women of childbearing potential or in nursing mothers unless, in the opinion of the physician, the potential benefits to the patient outweigh the possible hazards to the fetus or the infant. Teratology studies conducted in pregnant rats at ...
ighlights of prescribing information
... While there are useful tables of opioid equivalents readily available, there is substantial inter-patient variability in the relative potency of different opioid drugs and products. As such, it is safer to underestimate a patient's 24-hour oral morphine requirements and provide rescue medication (e. ...
... While there are useful tables of opioid equivalents readily available, there is substantial inter-patient variability in the relative potency of different opioid drugs and products. As such, it is safer to underestimate a patient's 24-hour oral morphine requirements and provide rescue medication (e. ...
Exelon WS-119-121-G PI highlighted EN
... administration. Activity of the enzyme returns to baseline levels about 9 hours after the maximum inhibitory effect has been achieved. In patients with Alzheimer’s disease, inhibition of AChE in CSF by rivastigmine was dose-dependent up to 6 mg given twice daily, the highest dose tested. Inhibition ...
... administration. Activity of the enzyme returns to baseline levels about 9 hours after the maximum inhibitory effect has been achieved. In patients with Alzheimer’s disease, inhibition of AChE in CSF by rivastigmine was dose-dependent up to 6 mg given twice daily, the highest dose tested. Inhibition ...
Core Data Sheet
... Budesonide has not been observed to interact with any drug used for the treatment of rhinitis. The metabolism of budesonide is primarily mediated by CYP3A4. Inhibitors of this enzyme, eg, ketoconazole and itraconazole, can therefore increase systemic exposure to budesonide several times. Since there ...
... Budesonide has not been observed to interact with any drug used for the treatment of rhinitis. The metabolism of budesonide is primarily mediated by CYP3A4. Inhibitors of this enzyme, eg, ketoconazole and itraconazole, can therefore increase systemic exposure to budesonide several times. Since there ...
Desmopressin Acetate Nasal Spray, 10 mcg per 0.1 mL
... Desmopressin Acetate Nasal Spray is indicated as antidiuretic replacement therapy in the management of central cranial diabetes insipidus and for management of the temporary polyuria and polydipsia following head trauma or surgery in the pituitary region. It is ineffective for the treatment of nephr ...
... Desmopressin Acetate Nasal Spray is indicated as antidiuretic replacement therapy in the management of central cranial diabetes insipidus and for management of the temporary polyuria and polydipsia following head trauma or surgery in the pituitary region. It is ineffective for the treatment of nephr ...
AVANDAMET ® Product Monograph - GlaxoSmithKline
... healthy volunteers who received rosiglitazone 8 mg once daily as monotherapy for 8 weeks, there was a statistically significant increase in median plasma volume (1.8 mL/kg) compared to placebo. In controlled clinical trials of patients with Type 2 diabetes, mild to moderate edema was observed at a g ...
... healthy volunteers who received rosiglitazone 8 mg once daily as monotherapy for 8 weeks, there was a statistically significant increase in median plasma volume (1.8 mL/kg) compared to placebo. In controlled clinical trials of patients with Type 2 diabetes, mild to moderate edema was observed at a g ...
DUAC Gel - GSK Source
... another formulation containing 1% clindamycin and 5% benzoyl peroxide at doses of 100, 500, or 2,000 mg per kg per day caused a dose-dependent increase in the incidence of keratoacanthoma at the treated skin site of male rats in a 2-year dermal carcinogenicity study in rats. In a 52-week photocarcin ...
... another formulation containing 1% clindamycin and 5% benzoyl peroxide at doses of 100, 500, or 2,000 mg per kg per day caused a dose-dependent increase in the incidence of keratoacanthoma at the treated skin site of male rats in a 2-year dermal carcinogenicity study in rats. In a 52-week photocarcin ...
Epinephrine_1871-01_PI_Art3 without Legend
... Treatment consists of a rapidly acting vasodilators or alpha-adrenergic blocking drugs and/or respiratory support. Epinephrine overdosage can also cause transient bradycardia followed by tachycardia, and these may be accompanied by potentially fatal cardiac arrhythmias. Premature ventricular contrac ...
... Treatment consists of a rapidly acting vasodilators or alpha-adrenergic blocking drugs and/or respiratory support. Epinephrine overdosage can also cause transient bradycardia followed by tachycardia, and these may be accompanied by potentially fatal cardiac arrhythmias. Premature ventricular contrac ...
MODULATION OF CARBON TETRACHLORIDE (CCL4) AND
... selected organ weights (heart, spleen, liver and kidney). In the pentobarbitone-induced sleeping time assessment, pentobarbitone at 50 mg/kg, administered one hour after the oral administration of MLE (250, 1000 and 4000 mg/kg) caused a dose dependent decrease (P < 0.05) in the rat sleeping time. Th ...
... selected organ weights (heart, spleen, liver and kidney). In the pentobarbitone-induced sleeping time assessment, pentobarbitone at 50 mg/kg, administered one hour after the oral administration of MLE (250, 1000 and 4000 mg/kg) caused a dose dependent decrease (P < 0.05) in the rat sleeping time. Th ...
Ofloxacin
Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.